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The map label for this gene is lipB

Identifier: 85058771

GI number: 85058771

Start: 1346196

End: 1346855

Strand: Reverse

Name: lipB

Synonym: SG0793

Alternate gene names: 85058771

Gene position: 1346855-1346196 (Counterclockwise)

Preceding gene: 85058772

Following gene: 85058770

Centisome position: 32.29

GC content: 61.21

Gene sequence:

>660_bases
GTGTCAGAGAGCCTGGTTATCCGCCAGCTTGGCCTGCAGCCCTATGAGCGGGTCTCGTTTGCGATGCACCGCTTCACCGA
TGCGCGTAGCACCGCCAGCGCTGATGAAATTTGGCTGGTACAGCATCCGCAGGTCTTTACTCAAGGTCAGGCCGGTAAAG
CCGAGCACCTGCTGCAGCCAGGTGCTATCCCGGTGGTACAAAGCGATCGCGGCGGTCAGGTGACCTTCCACGGTCCGGGC
CAGCAGGTAATGTATGTCCTGCTGGACCTGCGTCGTCGCCGGCTGGGCGTGCGTTCTCTTGTCACCCTGCTGGAGCAAAC
GATCGTCGCCACCCTGGCGTGCTTTTCAATTAGCGCCCATGCCCGCACCGACGCGCCGGGCGTCTACATCGGTGCCGATA
AGATCTGCTCGCTCGGTTTACGTATCCGCAAAGGCTGCTCATTCCACGGCCTGGCGCTGAACGTTGCCATGGATCTCTCG
CCCTTTTTGCGTATCAATCCCTGCGGCTATGCCGGCCTGCGCATGACGCAGGTGAGCGATTTAGCCCCCGGCACCGGCAT
CGACGACGTCGCGCCGGTATTACTTGCAGAATGCCTGCGGCTGATGAAGGCCTCCGCTGGTGAGATTCAAGGCTGGGATC
CGGCGTATTATGGCACCTGA

Upstream 100 bases:

>100_bases
TTACCATTACTGCTACCCACATCGAGCAGGTAGAAACGCTGTACGAAGAGCTGGGTAAAATCGATATTGTGCGTATGGTG
CTGTAAGCCGGGAGATAAAC

Downstream 100 bases:

>100_bases
GCCGCGGCAGACGGGCTGCACGGGTAGGTATTGGCCTTCAGGCCACGTTTTGCATTCACCCGCTGTGAACAACATGTTAT
AATTTTTAAAATTTTTTTGA

Product: lipoate-protein ligase B

Products: NA

Alternate protein names: Lipoate-protein ligase B; Lipoyl/octanoyl transferase; Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSESLVIRQLGLQPYERVSFAMHRFTDARSTASADEIWLVQHPQVFTQGQAGKAEHLLQPGAIPVVQSDRGGQVTFHGPG
QQVMYVLLDLRRRRLGVRSLVTLLEQTIVATLACFSISAHARTDAPGVYIGADKICSLGLRIRKGCSFHGLALNVAMDLS
PFLRINPCGYAGLRMTQVSDLAPGTGIDDVAPVLLAECLRLMKASAGEIQGWDPAYYGT

Sequences:

>Translated_219_residues
MSESLVIRQLGLQPYERVSFAMHRFTDARSTASADEIWLVQHPQVFTQGQAGKAEHLLQPGAIPVVQSDRGGQVTFHGPG
QQVMYVLLDLRRRRLGVRSLVTLLEQTIVATLACFSISAHARTDAPGVYIGADKICSLGLRIRKGCSFHGLALNVAMDLS
PFLRINPCGYAGLRMTQVSDLAPGTGIDDVAPVLLAECLRLMKASAGEIQGWDPAYYGT
>Mature_218_residues
SESLVIRQLGLQPYERVSFAMHRFTDARSTASADEIWLVQHPQVFTQGQAGKAEHLLQPGAIPVVQSDRGGQVTFHGPGQ
QVMYVLLDLRRRRLGVRSLVTLLEQTIVATLACFSISAHARTDAPGVYIGADKICSLGLRIRKGCSFHGLALNVAMDLSP
FLRINPCGYAGLRMTQVSDLAPGTGIDDVAPVLLAECLRLMKASAGEIQGWDPAYYGT

Specific function: Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate

COG id: COG0321

COG function: function code H; Lipoate-protein ligase B

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lipB family

Homologues:

Organism=Escherichia coli, GI87081767, Length=201, Percent_Identity=69.1542288557214, Blast_Score=301, Evalue=2e-83,
Organism=Saccharomyces cerevisiae, GI6323268, Length=153, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21355483, Length=113, Percent_Identity=38.0530973451327, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LIPB_SODGM (Q2NUV7)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_454473.1
- ProteinModelPortal:   Q2NUV7
- SMR:   Q2NUV7
- STRING:   Q2NUV7
- GeneID:   3868476
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0793
- NMPDR:   fig|343509.6.peg.1715
- eggNOG:   COG0321
- HOGENOM:   HBG716160
- OMA:   HPPVFTL
- PhylomeDB:   Q2NUV7
- BioCyc:   SGLO343509:SG0793-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00013
- InterPro:   IPR004143
- InterPro:   IPR000544
- InterPro:   IPR020605
- PIRSF:   PIRSF016262
- TIGRFAMs:   TIGR00214

Pfam domain/function: PF03099 BPL_LipA_LipB

EC number: =2.3.1.181

Molecular weight: Translated: 23763; Mature: 23632

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS01313 LIPB

Important sites: ACT_SITE 168-168

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESLVIRQLGLQPYERVSFAMHRFTDARSTASADEIWLVQHPQVFTQGQAGKAEHLLQP
CCCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHCCCCCCCCHHHHCCC
GAIPVVQSDRGGQVTFHGPGQQVMYVLLDLRRRRLGVRSLVTLLEQTIVATLACFSISAH
CCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
ARTDAPGVYIGADKICSLGLRIRKGCSFHGLALNVAMDLSPFLRINPCGYAGLRMTQVSD
CCCCCCEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCEEEHHHHH
LAPGTGIDDVAPVLLAECLRLMKASAGEIQGWDPAYYGT
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SESLVIRQLGLQPYERVSFAMHRFTDARSTASADEIWLVQHPQVFTQGQAGKAEHLLQP
CCCHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCHHCCCCCCCCHHHHCCC
GAIPVVQSDRGGQVTFHGPGQQVMYVLLDLRRRRLGVRSLVTLLEQTIVATLACFSISAH
CCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
ARTDAPGVYIGADKICSLGLRIRKGCSFHGLALNVAMDLSPFLRINPCGYAGLRMTQVSD
CCCCCCEEEECHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCEEECCCCCCCEEEHHHHH
LAPGTGIDDVAPVLLAECLRLMKASAGEIQGWDPAYYGT
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA