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The map label for this gene is ahpC [C]

Identifier: 85058620

GI number: 85058620

Start: 1103717

End: 1104319

Strand: Reverse

Name: ahpC [C]

Synonym: SG0642

Alternate gene names: 85058620

Gene position: 1104319-1103717 (Counterclockwise)

Preceding gene: 85058621

Following gene: 85058615

Centisome position: 26.48

GC content: 53.07

Gene sequence:

>603_bases
ATGGTCCTGGTCACTCGTCAAGCCCCCGATTTTACGGCTGCCGCCGTGCTCGGCAACGGTGAAATCGTTGACAATTTCAA
TCTTAAATCGCATATCCAGGGTAAACCGGCAGTCATTTTTTTCTGGCCGATGGACTTCACCTTTGTCTGCCCGTCCGAAT
TGATTGCGTTTGACAAACGCTACGCAGAATTTCAGAAGCGCGGCGTTGAAATCATCGGCGTGTCTTTCGATTCTGAGTTT
GTACACAACGCCTGGCGGCAAGTACCTACCGATAAAGGCGGTATCGGACCGGTTCAGTACCCCATGGTGGCGGATATCAA
ACGCGAAATCATTAAAGCTTACGGCATTGAACATTCAGACGCCGGCGTCGCTCTGCGCGGTTCGTTCTTAATCGACAAAG
ACGGGCTCGTCCGCCATCAGGTTGTTAACGATCTGCCGCTGGGCCGCAATGTCGACGAAATGATGCGCATGGTCGACGCA
CTGCAATTCCACGAAGAACACGGTGAAGTTTGCCCGGCACAGTGGGAAAAGGGACAGGAAGGGATGGGCGCTTCTCCGGA
AGGGGTTGCCAAATATCTGTCCGAGAACCTGACCAGGCTGTAA

Upstream 100 bases:

>100_bases
ACCAATCGGTACAGGTGACTTTATTCCCCCCCCGGTACGGCCTTATACTAGGTTGGCTCAAATCCTATCAATCCGCAAAC
GCTATTTTACAGGAGTTAAT

Downstream 100 bases:

>100_bases
GCGCCTTGCGTTCGTGCAGATAAGGCAGTCAAGGCAGTGACTCTGCCCGTATCACGCCGGTAGGCAACCCGACCGGCTTT
ATTTATGCCGAATGGTCAGG

Product: putative peroxidase

Products: NA

Alternate protein names: Thioredoxin reductase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MVLVTRQAPDFTAAAVLGNGEIVDNFNLKSHIQGKPAVIFFWPMDFTFVCPSELIAFDKRYAEFQKRGVEIIGVSFDSEF
VHNAWRQVPTDKGGIGPVQYPMVADIKREIIKAYGIEHSDAGVALRGSFLIDKDGLVRHQVVNDLPLGRNVDEMMRMVDA
LQFHEEHGEVCPAQWEKGQEGMGASPEGVAKYLSENLTRL

Sequences:

>Translated_200_residues
MVLVTRQAPDFTAAAVLGNGEIVDNFNLKSHIQGKPAVIFFWPMDFTFVCPSELIAFDKRYAEFQKRGVEIIGVSFDSEF
VHNAWRQVPTDKGGIGPVQYPMVADIKREIIKAYGIEHSDAGVALRGSFLIDKDGLVRHQVVNDLPLGRNVDEMMRMVDA
LQFHEEHGEVCPAQWEKGQEGMGASPEGVAKYLSENLTRL
>Mature_200_residues
MVLVTRQAPDFTAAAVLGNGEIVDNFNLKSHIQGKPAVIFFWPMDFTFVCPSELIAFDKRYAEFQKRGVEIIGVSFDSEF
VHNAWRQVPTDKGGIGPVQYPMVADIKREIIKAYGIEHSDAGVALRGSFLIDKDGLVRHQVVNDLPLGRNVDEMMRMVDA
LQFHEEHGEVCPAQWEKGQEGMGASPEGVAKYLSENLTRL

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=188, Percent_Identity=46.8085106382979, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI32455266, Length=188, Percent_Identity=46.8085106382979, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI32455264, Length=188, Percent_Identity=46.8085106382979, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI32189392, Length=193, Percent_Identity=45.0777202072539, Blast_Score=189, Evalue=1e-48,
Organism=Homo sapiens, GI5453549, Length=193, Percent_Identity=43.5233160621762, Blast_Score=177, Evalue=4e-45,
Organism=Homo sapiens, GI5802974, Length=192, Percent_Identity=42.7083333333333, Blast_Score=174, Evalue=7e-44,
Organism=Homo sapiens, GI32483377, Length=191, Percent_Identity=42.4083769633508, Blast_Score=172, Evalue=3e-43,
Organism=Homo sapiens, GI33188454, Length=84, Percent_Identity=47.6190476190476, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI4758638, Length=208, Percent_Identity=29.3269230769231, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1786822, Length=192, Percent_Identity=32.8125, Blast_Score=117, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17554494, Length=171, Percent_Identity=43.859649122807, Blast_Score=166, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI193204376, Length=194, Percent_Identity=42.2680412371134, Blast_Score=163, Evalue=5e-41,
Organism=Caenorhabditis elegans, GI32565831, Length=194, Percent_Identity=42.2680412371134, Blast_Score=163, Evalue=6e-41,
Organism=Caenorhabditis elegans, GI25153706, Length=180, Percent_Identity=28.8888888888889, Blast_Score=74, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=190, Percent_Identity=39.4736842105263, Blast_Score=161, Evalue=8e-41,
Organism=Saccharomyces cerevisiae, GI6320661, Length=175, Percent_Identity=38.8571428571429, Blast_Score=146, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319407, Length=185, Percent_Identity=29.1891891891892, Blast_Score=88, Evalue=9e-19,
Organism=Drosophila melanogaster, GI24656348, Length=194, Percent_Identity=46.3917525773196, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17864676, Length=194, Percent_Identity=46.3917525773196, Blast_Score=189, Evalue=1e-48,
Organism=Drosophila melanogaster, GI17738015, Length=197, Percent_Identity=42.1319796954315, Blast_Score=176, Evalue=1e-44,
Organism=Drosophila melanogaster, GI17157991, Length=193, Percent_Identity=43.0051813471503, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24641739, Length=193, Percent_Identity=43.0051813471503, Blast_Score=173, Evalue=7e-44,
Organism=Drosophila melanogaster, GI21357347, Length=193, Percent_Identity=41.9689119170984, Blast_Score=172, Evalue=2e-43,
Organism=Drosophila melanogaster, GI24581278, Length=182, Percent_Identity=32.4175824175824, Blast_Score=97, Evalue=7e-21,
Organism=Drosophila melanogaster, GI17975518, Length=156, Percent_Identity=32.0512820512821, Blast_Score=74, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24652436, Length=156, Percent_Identity=32.0512820512821, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24652434, Length=156, Percent_Identity=32.0512820512821, Blast_Score=74, Evalue=8e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 22321; Mature: 22321

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVTRQAPDFTAAAVLGNGEIVDNFNLKSHIQGKPAVIFFWPMDFTFVCPSELIAFDKR
CEEEECCCCCCEEEEEECCCCEEECCCCHHHCCCCCEEEEEECCCEEEECHHHHHHHHHH
YAEFQKRGVEIIGVSFDSEFVHNAWRQVPTDKGGIGPVQYPMVADIKREIIKAYGIEHSD
HHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
AGVALRGSFLIDKDGLVRHQVVNDLPLGRNVDEMMRMVDALQFHEEHGEVCPAQWEKGQE
CCEEEECEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
GMGASPEGVAKYLSENLTRL
CCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVLVTRQAPDFTAAAVLGNGEIVDNFNLKSHIQGKPAVIFFWPMDFTFVCPSELIAFDKR
CEEEECCCCCCEEEEEECCCCEEECCCCHHHCCCCCEEEEEECCCEEEECHHHHHHHHHH
YAEFQKRGVEIIGVSFDSEFVHNAWRQVPTDKGGIGPVQYPMVADIKREIIKAYGIEHSD
HHHHHHCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCC
AGVALRGSFLIDKDGLVRHQVVNDLPLGRNVDEMMRMVDALQFHEEHGEVCPAQWEKGQE
CCEEEECEEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHCCCCC
GMGASPEGVAKYLSENLTRL
CCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]