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The map label for this gene is degQ [H]

Identifier: 85058191

GI number: 85058191

Start: 390966

End: 392336

Strand: Reverse

Name: degQ [H]

Synonym: SG0213

Alternate gene names: 85058191

Gene position: 392336-390966 (Counterclockwise)

Preceding gene: 85058192

Following gene: 85058190

Centisome position: 9.41

GC content: 57.26

Gene sequence:

>1371_bases
ATGAAAACGACACCACTCTTCAGCGCACTGGCACTCAGCATCGGGCTGAGCCTGATTCCTTTTTCGGCGCCGCAGGCGGC
GCTGCCGGCCGAAGTGGCGGGGCAATCCATGCCAAGCCTGGCGCCCATGCTGACTAAAGTTCTGCCAGCGGTAGTAAGCG
TTCACGTCGAAGGCTCCCAACCGGTCCGACGTCCCGCACTACCCAAGGAGTTCAAATATTTCTTCGGGCCCGACACCCCG
GGCGGTAACGGTGGATCGCGCCCGTTTGAAGGGTTGGGTTCAGGGGTCATCATCAACGCCGCAAAAGGCTATGTAATTAC
CAATAATCACGTGGTCAACGGCGCAGACAAGATTAAAGTGCAGCTTAATGACGGCCGTGAATTCGATGCCAAGCTGGTGG
GGCACGATGAGCAGACCGATCTGGCGCTATTGCAATTGCCTGCGCCGAAAAACCTCAGCGAGGTGACCATGGCCGACTCC
GATACGCTGAAAGTCGGCGATTTTGCCGTCGCGGTAGGCAATCCGTTCGGTCTCGGCCAGACCGCCACGTCCGGTATTGT
TTCCGCTCTGGGCCGCAGCGGCCTCAATCTGGAAGGCCTGGAAAACTTCATCCAGACCGATGCGTCCATTAACCGCGGCA
ATTCCGGCGGCGCGCTGGTCAATCTTAACGGCGAGCTGATTGGTATCAATACCGCCATTCTGGCACCGGGGGGTGGTAAC
ATCGGTATCGGCTTCGCTATCCCCAGCAATATCGTCAAAAACTTGAGTCAGCAATTAATTGAATATGGCGAAGTCAAACG
CGGTCAATTGGGTATCAAAGGCACCGAGCTGACCGCCGATATTGCCAAAGCCTTCAATATCGATGCTCAGAGTGGCGCCT
TCGTCAGCGAAGTGCTGCCGAATTCCGCCGCCGCCAAAGCCGGTATCAAAGCCGGCGATATCATTGTTTCGGTGGAAGGC
AAACCGATTCAGAGTTTCGCCGAACTGCGGGTGAAGGTCGGTACTACCGCACCCGGTAAAACCGTCAAGCTTGGCCTGCT
GCGCAACGGCAAAGTGCAAACGGCCTCGGTGGTCCTGGATGACAACGCATCCGCCACCACAAGCGAAGAGATCCTCACCC
AGGCGCTACAAGGGGCTTCCCTCAGCAATGGCCAACTGAAAAATGGCACCAAGGGCGTTCAGGTGGAGGAAGTGGTGAAA
GACTCCCCCGCCGCCGCAATCGGTCTGCAAAAGGGCGATGTGATTGTCGGTTTGAACCGCGAACGGGTACAAAGCGTCGC
GCAGCTGCGTAAAGTGCTGGAGGCCAAACCGGCGGTCATGGCGCTGAACATCGTGCGCGGTGACGCGGATATTTACCTGT
TATTGCGCTAA

Upstream 100 bases:

>100_bases
ACTTTTCCCCTCCCGGCAGGGTCATAATGGCGATTATGATGCCATCACCGGATGCCTGGACCAGGGTATCTGATACGAAA
ACGAGCGAGTTAAGGTTACA

Downstream 100 bases:

>100_bases
GCATTTAAAAAACGGACGCCGGCGCTGCGGTGTCCGTTTAACTCGTGCTATCCTGCCGCTATTTTCCACTATCCCTGCGA
GTCCCATGCTCCTAAAGTTG

Product: serine protease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 456; Mature: 456

Protein sequence:

>456_residues
MKTTPLFSALALSIGLSLIPFSAPQAALPAEVAGQSMPSLAPMLTKVLPAVVSVHVEGSQPVRRPALPKEFKYFFGPDTP
GGNGGSRPFEGLGSGVIINAAKGYVITNNHVVNGADKIKVQLNDGREFDAKLVGHDEQTDLALLQLPAPKNLSEVTMADS
DTLKVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPGGGN
IGIGFAIPSNIVKNLSQQLIEYGEVKRGQLGIKGTELTADIAKAFNIDAQSGAFVSEVLPNSAAAKAGIKAGDIIVSVEG
KPIQSFAELRVKVGTTAPGKTVKLGLLRNGKVQTASVVLDDNASATTSEEILTQALQGASLSNGQLKNGTKGVQVEEVVK
DSPAAAIGLQKGDVIVGLNRERVQSVAQLRKVLEAKPAVMALNIVRGDADIYLLLR

Sequences:

>Translated_456_residues
MKTTPLFSALALSIGLSLIPFSAPQAALPAEVAGQSMPSLAPMLTKVLPAVVSVHVEGSQPVRRPALPKEFKYFFGPDTP
GGNGGSRPFEGLGSGVIINAAKGYVITNNHVVNGADKIKVQLNDGREFDAKLVGHDEQTDLALLQLPAPKNLSEVTMADS
DTLKVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPGGGN
IGIGFAIPSNIVKNLSQQLIEYGEVKRGQLGIKGTELTADIAKAFNIDAQSGAFVSEVLPNSAAAKAGIKAGDIIVSVEG
KPIQSFAELRVKVGTTAPGKTVKLGLLRNGKVQTASVVLDDNASATTSEEILTQALQGASLSNGQLKNGTKGVQVEEVVK
DSPAAAIGLQKGDVIVGLNRERVQSVAQLRKVLEAKPAVMALNIVRGDADIYLLLR
>Mature_456_residues
MKTTPLFSALALSIGLSLIPFSAPQAALPAEVAGQSMPSLAPMLTKVLPAVVSVHVEGSQPVRRPALPKEFKYFFGPDTP
GGNGGSRPFEGLGSGVIINAAKGYVITNNHVVNGADKIKVQLNDGREFDAKLVGHDEQTDLALLQLPAPKNLSEVTMADS
DTLKVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPGGGN
IGIGFAIPSNIVKNLSQQLIEYGEVKRGQLGIKGTELTADIAKAFNIDAQSGAFVSEVLPNSAAAKAGIKAGDIIVSVEG
KPIQSFAELRVKVGTTAPGKTVKLGLLRNGKVQTASVVLDDNASATTSEEILTQALQGASLSNGQLKNGTKGVQVEEVVK
DSPAAAIGLQKGDVIVGLNRERVQSVAQLRKVLEAKPAVMALNIVRGDADIYLLLR

Specific function: Protease with a shared specificity with degP [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI22129776, Length=317, Percent_Identity=37.8548895899054, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI4506141, Length=248, Percent_Identity=39.5161290322581, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI24308541, Length=255, Percent_Identity=36.078431372549, Blast_Score=143, Evalue=3e-34,
Organism=Homo sapiens, GI7019477, Length=316, Percent_Identity=31.9620253164557, Blast_Score=128, Evalue=1e-29,
Organism=Escherichia coli, GI1789629, Length=456, Percent_Identity=68.640350877193, Blast_Score=613, Evalue=1e-176,
Organism=Escherichia coli, GI1786356, Length=458, Percent_Identity=59.1703056768559, Blast_Score=528, Evalue=1e-151,
Organism=Escherichia coli, GI1789630, Length=359, Percent_Identity=40.9470752089136, Blast_Score=217, Evalue=1e-57,
Organism=Drosophila melanogaster, GI24646839, Length=318, Percent_Identity=33.0188679245283, Blast_Score=130, Evalue=2e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 47041; Mature: 47041

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTPLFSALALSIGLSLIPFSAPQAALPAEVAGQSMPSLAPMLTKVLPAVVSVHVEGSQ
CCCCHHHHHHHHHHCCCEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHEEEEECCCC
PVRRPALPKEFKYFFGPDTPGGNGGSRPFEGLGSGVIINAAKGYVITNNHVVNGADKIKV
CCCCCCCCCHHHEEECCCCCCCCCCCCCHHHCCCCEEEEECCCEEEECCEEECCCEEEEE
QLNDGREFDAKLVGHDEQTDLALLQLPAPKNLSEVTMADSDTLKVGDFAVAVGNPFGLGQ
EECCCCCCCEEEECCCCCCCEEEEECCCCCCCCCEEECCCCCEEECCEEEEECCCCCCCC
TATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPGGGN
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCC
IGIGFAIPSNIVKNLSQQLIEYGEVKRGQLGIKGTELTADIAKAFNIDAQSGAFVSEVLP
EEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCC
NSAAAKAGIKAGDIIVSVEGKPIQSFAELRVKVGTTAPGKTVKLGLLRNGKVQTASVVLD
CCHHHHCCCCCCCEEEEECCCCHHHHHHEEEEECCCCCCCEEEEEEEECCCEEEEEEEEE
DNASATTSEEILTQALQGASLSNGQLKNGTKGVQVEEVVKDSPAAAIGLQKGDVIVGLNR
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCEEEECCH
ERVQSVAQLRKVLEAKPAVMALNIVRGDADIYLLLR
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEC
>Mature Secondary Structure
MKTTPLFSALALSIGLSLIPFSAPQAALPAEVAGQSMPSLAPMLTKVLPAVVSVHVEGSQ
CCCCHHHHHHHHHHCCCEEECCCCCCCCCHHHHCCCCCHHHHHHHHHHHHHEEEEECCCC
PVRRPALPKEFKYFFGPDTPGGNGGSRPFEGLGSGVIINAAKGYVITNNHVVNGADKIKV
CCCCCCCCCHHHEEECCCCCCCCCCCCCHHHCCCCEEEEECCCEEEECCEEECCCEEEEE
QLNDGREFDAKLVGHDEQTDLALLQLPAPKNLSEVTMADSDTLKVGDFAVAVGNPFGLGQ
EECCCCCCCEEEECCCCCCCEEEEECCCCCCCCCEEECCCCCEEECCEEEEECCCCCCCC
TATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALVNLNGELIGINTAILAPGGGN
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCEEEEECCEEEEEEEEEEECCCCC
IGIGFAIPSNIVKNLSQQLIEYGEVKRGQLGIKGTELTADIAKAFNIDAQSGAFVSEVLP
EEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHCC
NSAAAKAGIKAGDIIVSVEGKPIQSFAELRVKVGTTAPGKTVKLGLLRNGKVQTASVVLD
CCHHHHCCCCCCCEEEEECCCCHHHHHHEEEEECCCCCCCEEEEEEEECCCEEEEEEEEE
DNASATTSEEILTQALQGASLSNGQLKNGTKGVQVEEVVKDSPAAAIGLQKGDVIVGLNR
CCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCEEEECCH
ERVQSVAQLRKVLEAKPAVMALNIVRGDADIYLLLR
HHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8576051; 9278503 [H]