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The map label for this gene is lptA [H]

Identifier: 85058179

GI number: 85058179

Start: 380881

End: 381444

Strand: Reverse

Name: lptA [H]

Synonym: SG0201

Alternate gene names: 85058179

Gene position: 381444-380881 (Counterclockwise)

Preceding gene: 85058180

Following gene: 85058178

Centisome position: 9.14

GC content: 56.21

Gene sequence:

>564_bases
TTGAAAAGGTTAAGACCTCTTATGAAATCCAGAATTCACAACGTACGCCCTAGCCTGCTTCTGGCCGGCGGCTTAATGCT
GGCCAGCGCGCAGGCGCTGGCGCTGGCCAGCGACAATCAGCAGCCGATTCATATCGACTCCGCGCAGCAGGCGGTAGATA
TGGCGACCAATACCGTGACCTTCACCGGTGAGGTCGTGGTCAAGCGCGGTTCAATCGACATTCGCGCCGACAAGGTCGTC
ATCACCCGCCCCGACGGAAAGGACGGTAACGAAGTCGTGGAAAGCTACGGTAATCCAGTCACTTTCTATCAACTGCAGGA
CGACGGCAAGCCGGTGCGCGGTCATTCGCAGAAGGTGCGTTACGAAACCACCAACGATCTGGTGATTCTGACGGGCAATG
CCTATCTGGAGCAGTTGGACAGCAACGTGAAAGGCGATCGCATTACCTATTTGGTCAAGAAACAGCGGATGGAGGTGTTC
AGCGATAAAGGCAAACAGGTCACCACCGTGCTGGTACCGGCGCAGCTGCAGGATAAAAGCGGCGCCAAAGCGCCGGCGAA
ATAA

Upstream 100 bases:

>100_bases
GACGTCTCCTCGGATGATGAGGTAACCTTATATGGTACCGGCTTTAACTCCACCGGCATGAAGATGCGCGGCAATCTGCG
CAACAAGACCGCCGAGTTGA

Downstream 100 bases:

>100_bases
TCGGGTATAGGATCCATGGCAACATTAATCGCAGAAAATTTGGCTAAAGCCTATAAAGAGCGCCGCGTGGTGGAAGACGT
CAGCCTGAAGGTAAGCTCTG

Product: lipopolysaccharide transport periplasmic protein LptA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 187; Mature: 187

Protein sequence:

>187_residues
MKRLRPLMKSRIHNVRPSLLLAGGLMLASAQALALASDNQQPIHIDSAQQAVDMATNTVTFTGEVVVKRGSIDIRADKVV
ITRPDGKDGNEVVESYGNPVTFYQLQDDGKPVRGHSQKVRYETTNDLVILTGNAYLEQLDSNVKGDRITYLVKKQRMEVF
SDKGKQVTTVLVPAQLQDKSGAKAPAK

Sequences:

>Translated_187_residues
MKRLRPLMKSRIHNVRPSLLLAGGLMLASAQALALASDNQQPIHIDSAQQAVDMATNTVTFTGEVVVKRGSIDIRADKVV
ITRPDGKDGNEVVESYGNPVTFYQLQDDGKPVRGHSQKVRYETTNDLVILTGNAYLEQLDSNVKGDRITYLVKKQRMEVF
SDKGKQVTTVLVPAQLQDKSGAKAPAK
>Mature_187_residues
MKRLRPLMKSRIHNVRPSLLLAGGLMLASAQALALASDNQQPIHIDSAQQAVDMATNTVTFTGEVVVKRGSIDIRADKVV
ITRPDGKDGNEVVESYGNPVTFYQLQDDGKPVRGHSQKVRYETTNDLVILTGNAYLEQLDSNVKGDRITYLVKKQRMEVF
SDKGKQVTTVLVPAQLQDKSGAKAPAK

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=181, Percent_Identity=58.0110497237569, Blast_Score=226, Evalue=7e-61,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 20516; Mature: 20516

Theoretical pI: Translated: 10.10; Mature: 10.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRLRPLMKSRIHNVRPSLLLAGGLMLASAQALALASDNQQPIHIDSAQQAVDMATNTVT
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHHHCCEEE
FTGEVVVKRGSIDIRADKVVITRPDGKDGNEVVESYGNPVTFYQLQDDGKPVRGHSQKVR
EEEEEEEEECCEEEEECEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEE
YETTNDLVILTGNAYLEQLDSNVKGDRITYLVKKQRMEVFSDKGKQVTTVLVPAQLQDKS
EECCCCEEEEECCHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEEEECEECCCC
GAKAPAK
CCCCCCC
>Mature Secondary Structure
MKRLRPLMKSRIHNVRPSLLLAGGLMLASAQALALASDNQQPIHIDSAQQAVDMATNTVT
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHCCEEEEECCCCCCEEECCHHHHHHHHCCEEE
FTGEVVVKRGSIDIRADKVVITRPDGKDGNEVVESYGNPVTFYQLQDDGKPVRGHSQKVR
EEEEEEEEECCEEEEECEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEE
YETTNDLVILTGNAYLEQLDSNVKGDRITYLVKKQRMEVFSDKGKQVTTVLVPAQLQDKS
EECCCCEEEEECCHHHHHHCCCCCCCEEEEEHHHHHHHHHHCCCCEEEEEEEECEECCCC
GAKAPAK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]