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The map label for this gene is aroQ

Identifier: 85058132

GI number: 85058132

Start: 273291

End: 273743

Strand: Reverse

Name: aroQ

Synonym: SG0154

Alternate gene names: 85058132

Gene position: 273743-273291 (Counterclockwise)

Preceding gene: 85058140

Following gene: 85058131

Centisome position: 6.56

GC content: 54.97

Gene sequence:

>453_bases
ATGGCCGATAAGTTCCACATTTTGCTTCTCAATGGGCCGAACCTGAATTTGCTCGGCACCCGCGAACCGGACAAGTATGG
TCATACCACGCTTGCCGACATTACCGCGGACCTGAGCGCGCTGGCCGGCAGCTTGGGGGCAGAATTCAGCCATTTTCAAT
CCAATGCGGAGCATGCGCTGATCGACCGTATCCATCAGGCCCGGGGCAATACCGATTTTATCGTTATCAACCCCGCGGCG
TTTACCCATACCAGCGTCGCCCTGCGCGATGCGCTGTTAGCGGTAAACATCCCGTTCATTGAGATTCACCTCTCCAATGT
CCATGCGCGGGAACCTTTCCGTCATCACTCCTATCTGTCCGATATTGCGATTGGCGTTATATGCGGCCTCGGCGCCGATG
GGTATCACTTTGCTTTACAGACGGCGGTCAAACGCCTGTCCACATCCAATTAA

Upstream 100 bases:

>100_bases
ATGGCAAATCAGCACCGAAATGTCAGCAAAAAGATGACAAATCGTTTACCGTTGGTTATTTTCTACGTGGTAACGTAAAT
TGAAGGGAGATCGCCGCACA

Downstream 100 bases:

>100_bases
TTAGAGTATGGAACCCCACTCATGGATATTCGTAAGATCAAGAAACTGATTGAACTGGTTGAAGAATCCGGCATTTCCGA
GCTGGAAATTTCTGAAGGTG

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MADKFHILLLNGPNLNLLGTREPDKYGHTTLADITADLSALAGSLGAEFSHFQSNAEHALIDRIHQARGNTDFIVINPAA
FTHTSVALRDALLAVNIPFIEIHLSNVHAREPFRHHSYLSDIAIGVICGLGADGYHFALQTAVKRLSTSN

Sequences:

>Translated_150_residues
MADKFHILLLNGPNLNLLGTREPDKYGHTTLADITADLSALAGSLGAEFSHFQSNAEHALIDRIHQARGNTDFIVINPAA
FTHTSVALRDALLAVNIPFIEIHLSNVHAREPFRHHSYLSDIAIGVICGLGADGYHFALQTAVKRLSTSN
>Mature_149_residues
ADKFHILLLNGPNLNLLGTREPDKYGHTTLADITADLSALAGSLGAEFSHFQSNAEHALIDRIHQARGNTDFIVINPAAF
THTSVALRDALLAVNIPFIEIHLSNVHAREPFRHHSYLSDIAIGVICGLGADGYHFALQTAVKRLSTSN

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_SODGM (Q2NWP6)

Other databases:

- EMBL:   AP008232
- RefSeq:   YP_453834.1
- HSSP:   P15474
- ProteinModelPortal:   Q2NWP6
- SMR:   Q2NWP6
- STRING:   Q2NWP6
- GeneID:   3868520
- GenomeReviews:   AP008232_GR
- KEGG:   sgl:SG0154
- NMPDR:   fig|343509.6.peg.327
- eggNOG:   COG0757
- HOGENOM:   HBG284657
- OMA:   TFQSNHE
- ProtClustDB:   PRK05395
- BioCyc:   SGLO343509:SG0154-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16289; Mature: 16157

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 26-26 ACT_SITE 103-103 BINDING 77-77 BINDING 83-83 BINDING 90-90 BINDING 114-114

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKFHILLLNGPNLNLLGTREPDKYGHTTLADITADLSALAGSLGAEFSHFQSNAEHAL
CCCCEEEEEEECCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHCCCHHHH
IDRIHQARGNTDFIVINPAAFTHTSVALRDALLAVNIPFIEIHLSNVHAREPFRHHSYLS
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCHHHHHHHH
DIAIGVICGLGADGYHFALQTAVKRLSTSN
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ADKFHILLLNGPNLNLLGTREPDKYGHTTLADITADLSALAGSLGAEFSHFQSNAEHAL
CCCEEEEEEECCCEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHCCHHHHHHCCCHHHH
IDRIHQARGNTDFIVINPAAFTHTSVALRDALLAVNIPFIEIHLSNVHAREPFRHHSYLS
HHHHHHHCCCCCEEEECCCHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCHHHHHHHH
DIAIGVICGLGADGYHFALQTAVKRLSTSN
HHHHHHHHCCCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA