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The map label for this gene is fliI

Identifier: 85058028

GI number: 85058028

Start: 66483

End: 67859

Strand: Reverse

Name: fliI

Synonym: SG0050

Alternate gene names: 85058028

Gene position: 67859-66483 (Counterclockwise)

Preceding gene: 85058029

Following gene: 85058027

Centisome position: 1.63

GC content: 60.86

Gene sequence:

>1377_bases
ATGACCGTGCAGTTGGAACGCTGGATTAACGCGATGGCGCGCCAGGAACGCATGATTACCACCCTGCCGGACTGCCGCCA
CTACGGGCGGCTAACGCGGACGACCGGCATGGTGATGGAGGCGGTGGGGCTGCAATTACCCCTTGGCGCCACCTGTCTTA
TCGAACGCTATAACGGCAAGGCGGTAGGGCTGGTCGAAACGGAAGTCGTCGGGTTCAAGGGCCGGCAACTGTTTCTGATG
CCGCTGGAAAATGTGGAGGGCATCCTGCCCAGCGCCCGCGTCTATGCGCCGGGTTCAGCTAACAGCAAAGTCCCCGCCCG
CTTGCTTCCACTGGGTCCGGCGCTGTTGGGCCGCGTCCTCTGCGGCAGCGGGCAGCCGCTGGACAACCTGCCACCGCCGG
AAACCGGTTATCGCGCCTCACTCTACAGCCCGCCTCTTAATCCTCTCGCGCGCAGTCCCATCACGGATGTGCTCGATGTC
GGCGTGCGTGCGATTAATGGCCTGCTAACGGTAGGCCGCGGGCAACGTATGGGCTTATTTGCTGGCTCCGGCGTGGGCAA
AAGTATGCTGCTCGGCATGATGGCGCGCTATACCCAGGCTGATGTCATTGTCGTCGGCCTGATAGGCGAGCGTGGGCGCG
AGGTGAAAGATTTTATCGAAAATATCCTCGGCGAGGAGGGCATCGCCCGTGCGGTCATTATCGCCGCGCCGGCGGATGTT
TCACCCATGCTACGTATGCAGGGCGCCGCTTACGCCACGCGTATCGCCGAAGATTTTCGCGATCGCGGCAAGCATGTGCT
GCTCATTATGGACTCCCTGACGCGCTATGCGATGGCACAGCGCGAAATCGGTCTGGCCATCGGCGAGCCGCCAGCCACCA
AAGGCTATCCGCCGTCGGTATTCGCCAAATTGCCCACACTGGTGGAGCGTGCCGGCAACGGCGCGGACGGCGGCGGCTCG
ATCACAGCCTTTTATACCGTACTGACGGAAGGAGACGACCAGCAAGATCCCATCGCCGACGCTGCCCGGGCCATTCTGGA
TGGTCATGTGGTGTTGTCACGTCAGCTTGCCGAGTCAGGGCATTACCCTGCCATCGACATTGAGACGTCCATCAGTCGGG
CAATGACCGCCCTGGTAGATACAGCCCATTTTCAGCAAGTTCAACAGGTGAAGCAGTGGCTCGCCAGCTATCAGCGCAAT
CGCGATCTGCTCTCGGTAGGCGCCTACGCTGCCGGCAGCGACCCGCTGCTCGATCAGGCAATTGCCCATTATCCCCAGTT
GGAAAGCTATTTGCGCCAGGATGTCTCGCAACCTTGTAGTTACACCCAATCCTGTCAACAGCTGTCCGATCTCCTCATCC
CCCCTTCAACCGCATAA

Upstream 100 bases:

>100_bases
CGCGGCGGTTGCCGCATCATCGCCGAGGACGGCGAGGTGGATGCCACTCTGGAAACACGCTGGCAGCAGCTATGCCAGAT
GCTCAAGGAGGGCCTGCCGC

Downstream 100 bases:

>100_bases
GGAATCCTTCATGACCAGTACATCGCCTATCGAAACCTTGAGGGAGCATGCTGAACGGGCTTTGGAAGAAGCCCTGCTTC
AGCTCGGCGCCTGCCGCAGC

Product: flagellum-specific ATP synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 457

Protein sequence:

>458_residues
MTVQLERWINAMARQERMITTLPDCRHYGRLTRTTGMVMEAVGLQLPLGATCLIERYNGKAVGLVETEVVGFKGRQLFLM
PLENVEGILPSARVYAPGSANSKVPARLLPLGPALLGRVLCGSGQPLDNLPPPETGYRASLYSPPLNPLARSPITDVLDV
GVRAINGLLTVGRGQRMGLFAGSGVGKSMLLGMMARYTQADVIVVGLIGERGREVKDFIENILGEEGIARAVIIAAPADV
SPMLRMQGAAYATRIAEDFRDRGKHVLLIMDSLTRYAMAQREIGLAIGEPPATKGYPPSVFAKLPTLVERAGNGADGGGS
ITAFYTVLTEGDDQQDPIADAARAILDGHVVLSRQLAESGHYPAIDIETSISRAMTALVDTAHFQQVQQVKQWLASYQRN
RDLLSVGAYAAGSDPLLDQAIAHYPQLESYLRQDVSQPCSYTQSCQQLSDLLIPPSTA

Sequences:

>Translated_458_residues
MTVQLERWINAMARQERMITTLPDCRHYGRLTRTTGMVMEAVGLQLPLGATCLIERYNGKAVGLVETEVVGFKGRQLFLM
PLENVEGILPSARVYAPGSANSKVPARLLPLGPALLGRVLCGSGQPLDNLPPPETGYRASLYSPPLNPLARSPITDVLDV
GVRAINGLLTVGRGQRMGLFAGSGVGKSMLLGMMARYTQADVIVVGLIGERGREVKDFIENILGEEGIARAVIIAAPADV
SPMLRMQGAAYATRIAEDFRDRGKHVLLIMDSLTRYAMAQREIGLAIGEPPATKGYPPSVFAKLPTLVERAGNGADGGGS
ITAFYTVLTEGDDQQDPIADAARAILDGHVVLSRQLAESGHYPAIDIETSISRAMTALVDTAHFQQVQQVKQWLASYQRN
RDLLSVGAYAAGSDPLLDQAIAHYPQLESYLRQDVSQPCSYTQSCQQLSDLLIPPSTA
>Mature_457_residues
TVQLERWINAMARQERMITTLPDCRHYGRLTRTTGMVMEAVGLQLPLGATCLIERYNGKAVGLVETEVVGFKGRQLFLMP
LENVEGILPSARVYAPGSANSKVPARLLPLGPALLGRVLCGSGQPLDNLPPPETGYRASLYSPPLNPLARSPITDVLDVG
VRAINGLLTVGRGQRMGLFAGSGVGKSMLLGMMARYTQADVIVVGLIGERGREVKDFIENILGEEGIARAVIIAAPADVS
PMLRMQGAAYATRIAEDFRDRGKHVLLIMDSLTRYAMAQREIGLAIGEPPATKGYPPSVFAKLPTLVERAGNGADGGGSI
TAFYTVLTEGDDQQDPIADAARAILDGHVVLSRQLAESGHYPAIDIETSISRAMTALVDTAHFQQVQQVKQWLASYQRNR
DLLSVGAYAAGSDPLLDQAIAHYPQLESYLRQDVSQPCSYTQSCQQLSDLLIPPSTA

Specific function: Probable catalytic subunit of a protein translocase for flagellum-specific export, or a proton translocase involved in local circuits at the flagellum. May be involved in a specialized protein export pathway that proceeds without signal peptide cleavage [

COG id: COG1157

COG function: function code NU; Flagellar biosynthesis/type III secretory pathway ATPase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=338, Percent_Identity=28.698224852071, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI50345984, Length=390, Percent_Identity=26.4102564102564, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI4757810, Length=390, Percent_Identity=26.4102564102564, Blast_Score=121, Evalue=2e-27,
Organism=Homo sapiens, GI19913428, Length=351, Percent_Identity=25.0712250712251, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=351, Percent_Identity=24.2165242165242, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI19913424, Length=250, Percent_Identity=29.2, Blast_Score=102, Evalue=6e-22,
Organism=Escherichia coli, GI1788251, Length=438, Percent_Identity=74.6575342465753, Blast_Score=633, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=334, Percent_Identity=30.2395209580838, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790172, Length=359, Percent_Identity=25.3481894150418, Blast_Score=106, Evalue=3e-24,
Organism=Escherichia coli, GI1790217, Length=277, Percent_Identity=27.0758122743682, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25144756, Length=311, Percent_Identity=28.2958199356913, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71988080, Length=337, Percent_Identity=27.0029673590504, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71988063, Length=337, Percent_Identity=27.0029673590504, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=333, Percent_Identity=27.3273273273273, Blast_Score=112, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17510931, Length=327, Percent_Identity=26.9113149847095, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988074, Length=322, Percent_Identity=26.0869565217391, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17565854, Length=232, Percent_Identity=31.0344827586207, Blast_Score=102, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6322581, Length=368, Percent_Identity=27.9891304347826, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6319370, Length=346, Percent_Identity=28.3236994219653, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6319603, Length=292, Percent_Identity=27.7397260273973, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6320016, Length=197, Percent_Identity=31.9796954314721, Blast_Score=91, Evalue=5e-19,
Organism=Drosophila melanogaster, GI24638766, Length=390, Percent_Identity=26.4102564102564, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28574560, Length=340, Percent_Identity=29.4117647058824, Blast_Score=126, Evalue=4e-29,
Organism=Drosophila melanogaster, GI24658560, Length=339, Percent_Identity=28.023598820059, Blast_Score=119, Evalue=5e-27,
Organism=Drosophila melanogaster, GI281361666, Length=352, Percent_Identity=26.4204545454545, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646341, Length=352, Percent_Identity=26.4204545454545, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136796, Length=352, Percent_Identity=26.4204545454545, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI20129479, Length=309, Percent_Identity=27.1844660194175, Blast_Score=102, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583992, Length=240, Percent_Identity=30, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24583988, Length=242, Percent_Identity=29.7520661157025, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583986, Length=242, Percent_Identity=29.7520661157025, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24583984, Length=242, Percent_Identity=29.7520661157025, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005714
- InterPro:   IPR020005 [H]

Pfam domain/function: PF00006 ATP-synt_ab [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 49321; Mature: 49189

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQLERWINAMARQERMITTLPDCRHYGRLTRTTGMVMEAVGLQLPLGATCLIERYNGK
CCEEHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
AVGLVETEVVGFKGRQLFLMPLENVEGILPSARVYAPGSANSKVPARLLPLGPALLGRVL
EEEEEEEEEECCCCCEEEEEEHHCCCCCCCCCEEECCCCCCCCCCCCEECCCHHHHHHHH
CGSGQPLDNLPPPETGYRASLYSPPLNPLARSPITDVLDVGVRAINGLLTVGRGQRMGLF
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHEECCCCEEEEE
AGSGVGKSMLLGMMARYTQADVIVVGLIGERGREVKDFIENILGEEGIARAVIIAAPADV
ECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCC
SPMLRMQGAAYATRIAEDFRDRGKHVLLIMDSLTRYAMAQREIGLAIGEPPATKGYPPSV
CHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCEECCCCCCCCCCHHH
FAKLPTLVERAGNGADGGGSITAFYTVLTEGDDQQDPIADAARAILDGHVVLSRQLAESG
HHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HYPAIDIETSISRAMTALVDTAHFQQVQQVKQWLASYQRNRDLLSVGAYAAGSDPLLDQA
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHH
IAHYPQLESYLRQDVSQPCSYTQSCQQLSDLLIPPSTA
HHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TVQLERWINAMARQERMITTLPDCRHYGRLTRTTGMVMEAVGLQLPLGATCLIERYNGK
CEEHHHHHHHHHHHHHHHHCCCCHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEECCCCC
AVGLVETEVVGFKGRQLFLMPLENVEGILPSARVYAPGSANSKVPARLLPLGPALLGRVL
EEEEEEEEEECCCCCEEEEEEHHCCCCCCCCCEEECCCCCCCCCCCCEECCCHHHHHHHH
CGSGQPLDNLPPPETGYRASLYSPPLNPLARSPITDVLDVGVRAINGLLTVGRGQRMGLF
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHEECCCCEEEEE
AGSGVGKSMLLGMMARYTQADVIVVGLIGERGREVKDFIENILGEEGIARAVIIAAPADV
ECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCEEEEEECCCCC
SPMLRMQGAAYATRIAEDFRDRGKHVLLIMDSLTRYAMAQREIGLAIGEPPATKGYPPSV
CHHHHHCCHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHCCEECCCCCCCCCCHHH
FAKLPTLVERAGNGADGGGSITAFYTVLTEGDDQQDPIADAARAILDGHVVLSRQLAESG
HHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
HYPAIDIETSISRAMTALVDTAHFQQVQQVKQWLASYQRNRDLLSVGAYAAGSDPLLDQA
CCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCHHHHHH
IAHYPQLESYLRQDVSQPCSYTQSCQQLSDLLIPPSTA
HHHCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]