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The map label for this gene is proA [H]

Identifier: 84625958

GI number: 84625958

Start: 4858682

End: 4859353

Strand: Reverse

Name: proA [H]

Synonym: XOO_4301

Alternate gene names: 84625958

Gene position: 4859353-4858682 (Counterclockwise)

Preceding gene: 84625963

Following gene: 84625957

Centisome position: 98.36

GC content: 68.9

Gene sequence:

>672_bases
ATGAGCCAGGTCGTCACCCGGATCGAGCGCACCCCGCTGGCCGTCGTCGACGGGCTGGCGCAGGCCGGGGTCGCCACCGT
GCACGAAGCGCAGGGACACAGCGGCCTGCTGCACCACCGGCTACGCCCCATCTACGCCGGCTGCCGCATCGCCGGTACCG
CGGTCACCGTGTTGATTCCGCCCGGCGACAACTGGATGATGCATGTGGCCATCGAGCAACTGCACCCAGGCGATGTGCTG
GTGGTCGCGCCGACCAGCGACTGTTGCGACGGCTACTTCGGCGACCTGCTTGCCACTTCGGCGCAAGCGCGCGGTTGCCG
CGGGCTGATCATCGATGCCGGCGTGCGCGATGTGCGCGATCTCACCGCCATGCAGTTCCCGGCCTGGAGCCGCGCCATCT
GCGCGCAGGGCACCATCAAGGAGACGCTGGGTTCGGTCAACGTGCCCTTGGTGTGCGCCGGGCAAATGATCCAGCCCGGT
GATGTGGTGGTGGCCGACGACGATGGCGTGTGCGTGGTGCCGCGTGCCAGCGCCGCCGATGCGCTGGCCGAAGCGCAGGC
GCGCGAGGCACGCAAGCTGCGCAAGCGCGAGCGCCTGGCAAACGGCGAACTGGGCCTGGATATCTATGCAATGCGCGAAC
GCCTGGCCGCCAAGGGCCTGCGTTATGTCTGA

Upstream 100 bases:

>100_bases
CATGCTCTAACTATAATCAAAACCAATATGCATAGCTCAAATTGATCCTGAGCCAGCTGGCTCGCGGCGCACACACTCAG
CACATCACTAACGAGGATGG

Downstream 100 bases:

>100_bases
GCGCGTGCGCGCGATGTGGATGCGCGGCGGCACCTCCAAGGGCGGCTTTTTTCTGGCCGACGAGTTGCCTGCCGACCCCG
CCGCGCGCGATGCGTTTTTG

Product: hypothetical protein

Products: NA

Alternate protein names: 4-hydroxy-2-oxoglutarate aldolase [H]

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSQVVTRIERTPLAVVDGLAQAGVATVHEAQGHSGLLHHRLRPIYAGCRIAGTAVTVLIPPGDNWMMHVAIEQLHPGDVL
VVAPTSDCCDGYFGDLLATSAQARGCRGLIIDAGVRDVRDLTAMQFPAWSRAICAQGTIKETLGSVNVPLVCAGQMIQPG
DVVVADDDGVCVVPRASAADALAEAQAREARKLRKRERLANGELGLDIYAMRERLAAKGLRYV

Sequences:

>Translated_223_residues
MSQVVTRIERTPLAVVDGLAQAGVATVHEAQGHSGLLHHRLRPIYAGCRIAGTAVTVLIPPGDNWMMHVAIEQLHPGDVL
VVAPTSDCCDGYFGDLLATSAQARGCRGLIIDAGVRDVRDLTAMQFPAWSRAICAQGTIKETLGSVNVPLVCAGQMIQPG
DVVVADDDGVCVVPRASAADALAEAQAREARKLRKRERLANGELGLDIYAMRERLAAKGLRYV
>Mature_222_residues
SQVVTRIERTPLAVVDGLAQAGVATVHEAQGHSGLLHHRLRPIYAGCRIAGTAVTVLIPPGDNWMMHVAIEQLHPGDVLV
VAPTSDCCDGYFGDLLATSAQARGCRGLIIDAGVRDVRDLTAMQFPAWSRAICAQGTIKETLGSVNVPLVCAGQMIQPGD
VVVADDDGVCVVPRASAADALAEAQAREARKLRKRERLANGELGLDIYAMRERLAAKGLRYV

Specific function: Plays a role in protocatechuate degradation. Has a broad substrate specificity and catalyzes the aldol cleavage of 4- hydroxy-4-methyl-2-oxoglutarate, 4-hydroxy-2-oxoglutarate and 4- carboxy-4-hydroxy-2-oxoadipate, and the decarboxylation of oxaloacetate.

COG id: COG0684

COG function: function code H; Demethylmenaquinone methyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014165
- InterPro:   IPR005493 [H]

Pfam domain/function: PF03737 Methyltransf_6 [H]

EC number: =4.1.1.3; =4.1.3.16; =4.1.3.17 [H]

Molecular weight: Translated: 23727; Mature: 23595

Theoretical pI: Translated: 7.07; Mature: 7.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQVVTRIERTPLAVVDGLAQAGVATVHEAQGHSGLLHHRLRPIYAGCRIAGTAVTVLIP
CCHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEEECEEEEEEEC
PGDNWMMHVAIEQLHPGDVLVVAPTSDCCDGYFGDLLATSAQARGCRGLIIDAGVRDVRD
CCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
LTAMQFPAWSRAICAQGTIKETLGSVNVPLVCAGQMIQPGDVVVADDDGVCVVPRASAAD
HHHHCCCCHHHHHHCCCCHHHHHCCCCCCEEECCCEECCCCEEEECCCCEEEEECCCHHH
ALAEAQAREARKLRKRERLANGELGLDIYAMRERLAAKGLRYV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SQVVTRIERTPLAVVDGLAQAGVATVHEAQGHSGLLHHRLRPIYAGCRIAGTAVTVLIP
CHHHHHHHCCCHHHHHHHHHCCHHHHHHCCCCCCHHHHHHHHHHHCCEEECEEEEEEEC
PGDNWMMHVAIEQLHPGDVLVVAPTSDCCDGYFGDLLATSAQARGCRGLIIDAGVRDVRD
CCCCEEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHH
LTAMQFPAWSRAICAQGTIKETLGSVNVPLVCAGQMIQPGDVVVADDDGVCVVPRASAAD
HHHHCCCCHHHHHHCCCCHHHHHCCCCCCEEECCCEECCCCEEEECCCCEEEEECCCHHH
ALAEAQAREARKLRKRERLANGELGLDIYAMRERLAAKGLRYV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11826967 [H]