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The map label for this gene is exuT [H]

Identifier: 84625830

GI number: 84625830

Start: 4718653

End: 4720134

Strand: Reverse

Name: exuT [H]

Synonym: XOO_4173

Alternate gene names: 84625830

Gene position: 4720134-4718653 (Counterclockwise)

Preceding gene: 84625838

Following gene: 84625829

Centisome position: 95.55

GC content: 64.78

Gene sequence:

>1482_bases
ATGGTAGCGCTATCATCCGTGACGCAAGGCCACCCTCGTGCAGGTGCAGTGGTCGATGAATCGAATCGAAGAACGCGACA
GCGACGCGCCTGGCCGCCACCTGGTTGGCGCATGCAGAAGCGAGATCCGCCCACGCGTGCAGGCTGCCGACCATCCGGTG
CGGCCACGCAGGCCACGCGCATGAGCGAGGTGCCCACCGCTGCGTCGGCACGGCTCGGCAGGGTGCGTTGGCGCGTCTGT
GCCTTGCTGCTGGTCGCCACCACCATCAACTATGTGGACCGCCAGGTACTGGGCGTGCTGGCGCCGTTCCTGCAGACGCA
GATCGGCTGGAACGAAATCCAGTACGGCTACATCGTCACCGCATTCCAGGCGGCGTATGCGCTGGGGTTGCTGTGCAGCG
GCGCGGTGATCGACCGCTTCGGCACCTGGCTCGGCTATGCGCTGGCGATCGGCGTCTGGAGCCTGGCAGCGATGGGGCAT
GCCTTGGCCACCAGCGTCGTGGGCTTTGCGATCGCACGATTTTTCCTGGGCTTGGGCGAATCCGGGAATTTTCCTGCGGC
GCTGAAGACCGTGGCCGAATGGTTCCCGCGCCGCGAGCGCGCGCTGGCCACCGGCATCTTCAATTCCGGCTCCAATATCG
GTGCCATCGTCGCCCCGTTGCTGGTGCCGTTGATCGCCACGGCCTGGGGCTGGCAGTCGGCGTTTCTGTTTACTGGCGTG
CTCAGTGCCACCTGGCTGGCGGTGTGGTGGTTCCGGTATCACTCGCCCGAGCAACAGCCCGGATTGTCGGCCGCAGAGTT
GGCGCATATCCGCAGCGATGCGCATGAGCCGGTGCAGCGCCGGCTCTCCTGGTTGCAGGTGCTGCGGCATCGGCAGGCCT
GGGCATTTGTGCTGTGCAAGCTCATCACCGATCCGATCTGGTGGTTCTTCCTGTTCTGGCTGCCGAAGTTCCTGCATGCG
CAATACGGTTTGAGCCTGCTGCAGTTGGGCGCACCGTTGATCGAGATCTTCGTGCTGGCCGATATCGGCAGTATTGCCGG
TGGTTGGGTGGCAGGGCGTTTCATTGCGCGCGGCTGGAGCGTCAATCGCGCGCGCAAGACCGCGATGCTGATCTGCGCCA
TTTCTGTCGTGCCCATCGTGTTCGCTGCGCGTGCCGACAATCTATGGCTGGCGGTGGCATTGATCGGCCTAGCCACGGCG
GCACACCAGGGTTGGTCGGCCAATCTGTTTACGCTGCCGTCGGACATGTTTCCGCGGCATGCGGTTGCCACCGTGGTCGG
CATCGGTGGCTTCGCCGGTGCGGTGGGTGGCATGTTGATCGCCACCTTCATCGGCTTCCTGTTGCAGGCCACCGGCAGCT
ATGTGCCGGTATTTCTAATGGCGGGCTCGGCTTACCTGTTGGCGTTGGCCGTCGTACACACGCTGGTGCCGCGGCTGGAG
CCGGCGCAGTGGCATGCCGATCCAGCGCCGGCATCGTCCTGA

Upstream 100 bases:

>100_bases
CGGCCAGCAGCTACTGCGAGCGCTGCACAAGGCGCCTGGTTGTTTGCGTACGGACACGTCGTGCTGCACTGCGCGATGGA
TTTCGCGCAAGGCCGTGGTA

Downstream 100 bases:

>100_bases
GGTGAGCTGATGCACATGGGCGCAGTAACTCTGGGGTTGTGGGTGGCGGCTGGCATGGCGGCACCTGCCTACGCCGCACC
GCTGGCATCGAAGGCCGCCA

Product: putative hexuronate transporter

Products: galacturonate [Cytoplasm]; Proton [Cytoplasm]; glucuronate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MVALSSVTQGHPRAGAVVDESNRRTRQRRAWPPPGWRMQKRDPPTRAGCRPSGAATQATRMSEVPTAASARLGRVRWRVC
ALLLVATTINYVDRQVLGVLAPFLQTQIGWNEIQYGYIVTAFQAAYALGLLCSGAVIDRFGTWLGYALAIGVWSLAAMGH
ALATSVVGFAIARFFLGLGESGNFPAALKTVAEWFPRRERALATGIFNSGSNIGAIVAPLLVPLIATAWGWQSAFLFTGV
LSATWLAVWWFRYHSPEQQPGLSAAELAHIRSDAHEPVQRRLSWLQVLRHRQAWAFVLCKLITDPIWWFFLFWLPKFLHA
QYGLSLLQLGAPLIEIFVLADIGSIAGGWVAGRFIARGWSVNRARKTAMLICAISVVPIVFAARADNLWLAVALIGLATA
AHQGWSANLFTLPSDMFPRHAVATVVGIGGFAGAVGGMLIATFIGFLLQATGSYVPVFLMAGSAYLLALAVVHTLVPRLE
PAQWHADPAPASS

Sequences:

>Translated_493_residues
MVALSSVTQGHPRAGAVVDESNRRTRQRRAWPPPGWRMQKRDPPTRAGCRPSGAATQATRMSEVPTAASARLGRVRWRVC
ALLLVATTINYVDRQVLGVLAPFLQTQIGWNEIQYGYIVTAFQAAYALGLLCSGAVIDRFGTWLGYALAIGVWSLAAMGH
ALATSVVGFAIARFFLGLGESGNFPAALKTVAEWFPRRERALATGIFNSGSNIGAIVAPLLVPLIATAWGWQSAFLFTGV
LSATWLAVWWFRYHSPEQQPGLSAAELAHIRSDAHEPVQRRLSWLQVLRHRQAWAFVLCKLITDPIWWFFLFWLPKFLHA
QYGLSLLQLGAPLIEIFVLADIGSIAGGWVAGRFIARGWSVNRARKTAMLICAISVVPIVFAARADNLWLAVALIGLATA
AHQGWSANLFTLPSDMFPRHAVATVVGIGGFAGAVGGMLIATFIGFLLQATGSYVPVFLMAGSAYLLALAVVHTLVPRLE
PAQWHADPAPASS
>Mature_493_residues
MVALSSVTQGHPRAGAVVDESNRRTRQRRAWPPPGWRMQKRDPPTRAGCRPSGAATQATRMSEVPTAASARLGRVRWRVC
ALLLVATTINYVDRQVLGVLAPFLQTQIGWNEIQYGYIVTAFQAAYALGLLCSGAVIDRFGTWLGYALAIGVWSLAAMGH
ALATSVVGFAIARFFLGLGESGNFPAALKTVAEWFPRRERALATGIFNSGSNIGAIVAPLLVPLIATAWGWQSAFLFTGV
LSATWLAVWWFRYHSPEQQPGLSAAELAHIRSDAHEPVQRRLSWLQVLRHRQAWAFVLCKLITDPIWWFFLFWLPKFLHA
QYGLSLLQLGAPLIEIFVLADIGSIAGGWVAGRFIARGWSVNRARKTAMLICAISVVPIVFAARADNLWLAVALIGLATA
AHQGWSANLFTLPSDMFPRHAVATVVGIGGFAGAVGGMLIATFIGFLLQATGSYVPVFLMAGSAYLLALAVVHTLVPRLE
PAQWHADPAPASS

Specific function: Aldohexuronate transport system [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=419, Percent_Identity=25.7756563245823, Blast_Score=101, Evalue=1e-21,
Organism=Homo sapiens, GI21322234, Length=439, Percent_Identity=22.3234624145786, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI2367193, Length=430, Percent_Identity=33.7209302325581, Blast_Score=206, Evalue=3e-54,
Organism=Escherichia coli, GI87082320, Length=403, Percent_Identity=29.2803970223325, Blast_Score=174, Evalue=9e-45,
Organism=Escherichia coli, GI1789152, Length=441, Percent_Identity=26.530612244898, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789515, Length=416, Percent_Identity=28.125, Blast_Score=154, Evalue=9e-39,
Organism=Escherichia coli, GI2367379, Length=400, Percent_Identity=26.25, Blast_Score=142, Evalue=5e-35,
Organism=Escherichia coli, GI87082404, Length=358, Percent_Identity=23.7430167597765, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87082231, Length=223, Percent_Identity=26.0089686098655, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082071, Length=423, Percent_Identity=23.4042553191489, Blast_Score=70, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI115533556, Length=416, Percent_Identity=26.2019230769231, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115533554, Length=370, Percent_Identity=27.5675675675676, Blast_Score=82, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17535049, Length=425, Percent_Identity=21.6470588235294, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17552542, Length=290, Percent_Identity=27.9310344827586, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71991448, Length=251, Percent_Identity=26.2948207171315, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI71991453, Length=397, Percent_Identity=24.9370277078086, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI32565914, Length=382, Percent_Identity=21.7277486910995, Blast_Score=70, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI32565916, Length=234, Percent_Identity=24.3589743589744, Blast_Score=68, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560030, Length=216, Percent_Identity=24.0740740740741, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24583789, Length=405, Percent_Identity=24.4444444444444, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584153, Length=393, Percent_Identity=23.1552162849873, Blast_Score=83, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19920686, Length=394, Percent_Identity=21.5736040609137, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24580790, Length=295, Percent_Identity=24.406779661017, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648416, Length=388, Percent_Identity=23.1958762886598, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21356189, Length=388, Percent_Identity=23.1958762886598, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24639764, Length=336, Percent_Identity=25.8928571428571, Blast_Score=74, Evalue=3e-13,
Organism=Drosophila melanogaster, GI28573708, Length=402, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI28573707, Length=402, Percent_Identity=24.8756218905473, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24641682, Length=386, Percent_Identity=23.0569948186528, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI62484226, Length=317, Percent_Identity=23.9747634069401, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 53468; Mature: 53468

Theoretical pI: Translated: 10.99; Mature: 10.99

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCCCCCCC
>Mature Secondary Structure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CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: galacturonate [Periplasm]; Proton [Periplasm]; glucuronate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + galacturonate [Periplasm] = galacturonate [Cytoplasm] + Proton [Cytoplasm] Proton [Periplasm] + glucuronate [Periplasm] = Proton [Cytoplasm] + glucuronate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]