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The map label for this gene is namA [H]

Identifier: 84625752

GI number: 84625752

Start: 4618623

End: 4619741

Strand: Reverse

Name: namA [H]

Synonym: XOO_4095

Alternate gene names: 84625752

Gene position: 4619741-4618623 (Counterclockwise)

Preceding gene: 84625753

Following gene: 84625751

Centisome position: 93.51

GC content: 65.15

Gene sequence:

>1119_bases
ATGTCAGCTGTGGATGCCGCTTTGAGCCAGTTGTTCTCTCCCATCACCTTCGGTCCGCTCGCGCTCGCCAACCGGATTGT
CATTGCGCCGATGTGCCAGTACTCGGCACAGGACGGCTGCGCCACCGATTGGCATCGCATCCACCTGGGCACGTTGTCGC
AATCCGGCGCCGGATTGCTGATTCTCGAAGCGGCTGCGGTGGTGCCGGAAGGGCGCATCAGTTACGCCGATCTTGGTTTG
TACGACGATGCGACCGAGCAGGCCCTGGCCGAGGTACTGCAATCGGTACGACGCTGGTCGCCGATGCCGATTGGCATCCA
GCTGGCGCATGCCGGCCGCAAGGCGTCGACCGATCTGCCGTGGAAAGGCAGCGAGGCCATCGCACCCGATCATGCGCATG
GCTGGCAGACCGTGTCCGCATCGGCGATGCCGTTTCGCGCAGGGCAGCCGGCGCCACAGGCGCTGGATCAGGCGGGGATC
GATGCTGTGGTTGACGCCTTCGTCGCATCGGCACAACGTGCCGAGCGCCTGGGCCTGGAGTTGATCGAATTGCATGCCGC
GCATGGCTATTTGATGCATCAATTCCTGTCGCCCTTGAGCAACCAGCGCAGCGATGCGTATGGCGGGTCGCTGGAAAATC
GCATGCGGTTGACGCTGCGCATCTTCGATGCGGTGCGTGCGGCAGTCTCCGAAAAAATCGCCATTGGCGTGCGCATCTCG
GCCACCGACTGGGTCGAAGGCGGGTGGGATGTGCAGCAGAGCATCGCCTTGTCGCAGGCGCTGGATGCACGCGGTGCGCA
CTACATCCATGTCTCCAGCGGCGGGCTCGATCCACGCCAGCAGATTCCGCTGCAGGCGGGCTATCAGATTCCGTTCGCGC
AGGAGATTCGCGCGCAGGTGAGCAGGCCGGTGATCGGCGTAGGCTTGATCACCGAGCCAGCGCAGGCCGAAGCGATTGTG
CAGGAAGGCCAGGCCGATGCGATCGCGCTGGCGCGTGGCATCCTGTACGACCCACGCTGGCCGTGGCATGCCGCCGCGGC
ACTGGGCGCGTCGGTCACGCCGGCACCGCAATACCTGCGCTGCGAACCGCGCGACGCGCGCGGCGTGTTCGCCAACTGA

Upstream 100 bases:

>100_bases
CGTGCACGTCGCGTCAATGACGCCAGTGCGCGTTCTGCATGACGCAGCGATCCATCGCAGCGGTTGTGCCGGCGCGCGCA
GCGCAGTGCAATAGGCACCC

Downstream 100 bases:

>100_bases
TCCGTACCCCCGACGTCATACCGAACAAGGACAACGCATGCCGATAGGATTTCTGGGCTTGGGCACGATGGGCCTGCCGA
TGGCGCACAACCTGCTGCGT

Product: FMN oxidoreductase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSAVDAALSQLFSPITFGPLALANRIVIAPMCQYSAQDGCATDWHRIHLGTLSQSGAGLLILEAAAVVPEGRISYADLGL
YDDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGSEAIAPDHAHGWQTVSASAMPFRAGQPAPQALDQAGI
DAVVDAFVASAQRAERLGLELIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAIGVRIS
ATDWVEGGWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVSRPVIGVGLITEPAQAEAIV
QEGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDARGVFAN

Sequences:

>Translated_372_residues
MSAVDAALSQLFSPITFGPLALANRIVIAPMCQYSAQDGCATDWHRIHLGTLSQSGAGLLILEAAAVVPEGRISYADLGL
YDDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGSEAIAPDHAHGWQTVSASAMPFRAGQPAPQALDQAGI
DAVVDAFVASAQRAERLGLELIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAIGVRIS
ATDWVEGGWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVSRPVIGVGLITEPAQAEAIV
QEGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDARGVFAN
>Mature_371_residues
SAVDAALSQLFSPITFGPLALANRIVIAPMCQYSAQDGCATDWHRIHLGTLSQSGAGLLILEAAAVVPEGRISYADLGLY
DDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLPWKGSEAIAPDHAHGWQTVSASAMPFRAGQPAPQALDQAGID
AVVDAFVASAQRAERLGLELIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAIGVRISA
TDWVEGGWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQVSRPVIGVGLITEPAQAEAIVQ
EGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLRCEPRDARGVFAN

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787939, Length=347, Percent_Identity=30.2593659942363, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1789463, Length=331, Percent_Identity=25.0755287009063, Blast_Score=111, Evalue=7e-26,
Organism=Caenorhabditis elegans, GI17559802, Length=259, Percent_Identity=31.2741312741313, Blast_Score=129, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI72001454, Length=249, Percent_Identity=32.1285140562249, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI17559804, Length=249, Percent_Identity=30.9236947791165, Blast_Score=124, Evalue=9e-29,
Organism=Caenorhabditis elegans, GI17564188, Length=249, Percent_Identity=31.3253012048193, Blast_Score=124, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI17565138, Length=259, Percent_Identity=28.5714285714286, Blast_Score=111, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17540738, Length=260, Percent_Identity=28.4615384615385, Blast_Score=110, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17566914, Length=191, Percent_Identity=26.1780104712042, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6321973, Length=247, Percent_Identity=29.1497975708502, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=250, Percent_Identity=26, Blast_Score=83, Evalue=8e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 39747; Mature: 39616

Theoretical pI: Translated: 5.94; Mature: 5.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVDAALSQLFSPITFGPLALANRIVIAPMCQYSAQDGCATDWHRIHLGTLSQSGAGLL
CCHHHHHHHHHHCCCCCCHHHHHCCEEEEHHHHCCCCCCCCCCCEEEEEECCCCCCCCEE
ILEAAAVVPEGRISYADLGLYDDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLP
EEEHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
WKGSEAIAPDHAHGWQTVSASAMPFRAGQPAPQALDQAGIDAVVDAFVASAQRAERLGLE
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHCHH
LIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAIGVRIS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEE
ATDWVEGGWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQV
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHH
SRPVIGVGLITEPAQAEAIVQEGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLR
CCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCEE
CEPRDARGVFAN
CCCCCCCCCCCC
>Mature Secondary Structure 
SAVDAALSQLFSPITFGPLALANRIVIAPMCQYSAQDGCATDWHRIHLGTLSQSGAGLL
CHHHHHHHHHHCCCCCCHHHHHCCEEEEHHHHCCCCCCCCCCCEEEEEECCCCCCCCEE
ILEAAAVVPEGRISYADLGLYDDATEQALAEVLQSVRRWSPMPIGIQLAHAGRKASTDLP
EEEHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCC
WKGSEAIAPDHAHGWQTVSASAMPFRAGQPAPQALDQAGIDAVVDAFVASAQRAERLGLE
CCCCCCCCCCCCCCCCEECCCCCCCCCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHCHH
LIELHAAHGYLMHQFLSPLSNQRSDAYGGSLENRMRLTLRIFDAVRAAVSEKIAIGVRIS
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHEEEEEEEE
ATDWVEGGWDVQQSIALSQALDARGAHYIHVSSGGLDPRQQIPLQAGYQIPFAQEIRAQV
CCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHCCCCCCCCCCHHHHHHHHH
SRPVIGVGLITEPAQAEAIVQEGQADAIALARGILYDPRWPWHAAAALGASVTPAPQYLR
CCCEEEEEECCCCHHHHHHHHCCCCHHHHHHHHHCCCCCCCHHHHHHHCCCCCCCCCCEE
CEPRDARGVFAN
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA