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The map label for this gene is virA [H]

Identifier: 84624541

GI number: 84624541

Start: 3254485

End: 3256944

Strand: Direct

Name: virA [H]

Synonym: XOO_2884

Alternate gene names: 84624541

Gene position: 3254485-3256944 (Clockwise)

Preceding gene: 84624540

Following gene: 84624542

Centisome position: 65.88

GC content: 65.89

Gene sequence:

>2460_bases
ATGAGGTGGGCGACGATCCTCAGCGCCGTGCTGCTGGCGGGGCTGATTTTCTTCAGTCTGTGCATGGCGGCGCTGGATCG
CGACACGCAGCGTTACGGTCACGCGCTGGACGCACTCGACGCGCTGGACATGGCCGATACCAATCTCGACAACGACGTGC
TGAAGGCGCGCATTGGCCTGCTGCGCGACTACGACTCGCTGGTGACCGGCGATGCCCACGCACGCGACACCTTGCAGCAC
CTGCGCCGGCTGGCCGACCACGACCCTGCGTTGTGCCAGGCCATCGCCGCGCTGGACGCCGACTACACGGAGAAATCGCT
GCAGCGGGAGTTATTCAAATCGCAGAATTCGCTGCTGTCCAACTCGCTGGCCTACTTCTGGAGCGAGAGCAGCGCGCAGA
TCCGCCAAGGCGACGATCCCGCTGCGGCACGCGCAGCGAGCATGCTGGCAAGCGCCGTGCAACGCCTGAGTCTGGACACG
ACCGGCGAGGCGGTCGCACTGGCACGCCGGCGCCTGGACGAAGCGGCACAACGCACGACCAGCACGCCGCTGCTGCCGCA
TGGACGCATGCTGCTGAAGCTGTTGCCGGAGACCGATACCACCATCCGCCGCATGCGCCCGATCGCTTCGCTGGCCTCGT
ATGCACAGCTCAAGACGTATCTGCAAAAACAGCATGCCTGCCAGCAGGCCACCGCGCGCCAGGTCCGCTTCCTGTTGCTG
GGATTGGCCGTCGTCATGTTGGGCGCCTTGCTGTACCTGGCCACGTTGCTGCGGCAGCGCGCGCGGGTATTGCGTCGACG
CGCGGAGTTCGACCGCTTGATGGTTGCGGTGTCGCGCCGTCTTGTGGCCAACGATCGCCACCAGCTGGACGCTGGTATCG
AGGCCGGGCTGATGCGGTTGGCGAAGTGGGCGAAGCTGCCGAGTGCCCGCCTCGGCGTGGTATCCGTCGGCGCTGACGCG
CGAATCTGGCCCGATCCGCAGGACGAGGCCTTCCGCACCATGCTTGCCGCAGTGGCCGCCACCGGACCGGTCGCCGCCAG
CGACGTACTGGTCGTCCACGCCAATGGCACCGTCGAGGTGTTGGGCAAGCCCGAACGCGTGCGCGGCGCGCAGTGGCTCT
GCCTGCGGCAACACTCCGAAGCGGCGACGGTTGCACTGCTGTGCCTGCGGCTGCCGCCACTTTCCGCGCGCCGCGATCGT
GGCCTGGCGGCACCGGCCGAACTTCTGCCGCAGTTGCACATCGCGCTCGACACCTTGTTCGATGCACTGGAGCGACGGCG
ACTCGAAGACGAAGCCCGGGCGCTGGAACATCGCCTGGAACTGGCCCGGCGGATGGAAACGTTGGGGACAATGGCCAGCG
GCATTTCGCACAACTTCAACAACATCGTCGGCGCGATTCGTGGCAATGCCGAGATCGCCCTGTCCAAACTGGATCCGCAC
TCGCCGGCATCGGAGCACCTGCTCGAGATCAGCCACACCACGGCGCACGCTTACGATCTGATCGAATCCATCCTCAGTTT
CGGGCGGGTGCAGAATTACAACGTACAGCCGGTTGAGTTGAACGCCTTGCTGCAAGGCGCAGTTTCGCTGCTGTCGGTGT
CGCTGCCATCGACCGTCACGATCGCCCTGCAGCAGGAGCAGGAGCCACTGCACGCGCTGGGCAATCCAGCGCAACTGCAG
CAGGTCATCCTCAATCTGGCCAGCAACGCGGCGCAGGCGATGGACATGCGCGGGACGGTCACGATTCAACTGTCGGCCGC
CAAGGGCAGCGCAGCCGACGGCACGCCCCGTCGCATCGCGCAGCTGCGTGTCAGCGACCACGGCATCGGCATTCCTCCAG
ACCAACTGGATCGCATCTTCGATCTCTTCTTCACCACCCGCAATCGCGGCACCGGGCTGGGATTGGCAACGGTTCGCAAG
ATCATCGACAACCACGAAGGGCGGATCGACGTGGACAGCACGCTGTGTGTCGGCACGACCTTCGTGGTCGAGCTGCCACT
GCGGACAGGCATTGCAGCAGCCCCCCAGGCCGCGCCCTTGCCGAAGACGCGATCGCGGCATGCGAGCTTGCTGCTGCTGT
GCGACGACGCGGCCGAGCTCGACCGCCTGGAAGAAATGCTGGCCGCATTGGGACACGAACCGGTCGGCTTATTGGAGCTG
CCGGCAGCCGTCGCGATGGCAACGTCCGACCCGATGCGCTTCGATGGCGTGCTGCTCAAGCGCGATCGTGCCGGCGATGC
CGAACACGCGATCGACGCGCTGCATGCCGCTGCGCCGAAGCTGCCATTGATCCTCGCCACCCGTGCGATGAGCCTGGCGA
CACGCAAGGGTCTGGGCGGCGCCATCACCGAGATCATTGCGCAGCCGTTCGATCTGAGCGCGCTGGCGCTTGCGCTGGAA
CGTGCGCTGGGTCGCACGATGGACATGACAACGCAGGATGAGGGCACGCCTGCTCTGTGA

Upstream 100 bases:

>100_bases
TTGGCGTCGCACTGAGCCCTGCGGATGTCTCCGATATCGCTGCGTTTCTGAACACATTGACCGGCAAGCACCAGGGTCGG
CAGCTGACGGCGCCCCACCC

Downstream 100 bases:

>100_bases
CAAATGAAACACAGTCGCCGCAGATCGACACCGGAACGTAGCGCGGGCTGCCTAGCCTAGTGGATGCCCAGGCGCAGTAA
GCCGCCTGCATTCCACGACG

Product: two-component VirA-like sensor kinase

Products: NA

Alternate protein names: WHR virA [H]

Number of amino acids: Translated: 819; Mature: 819

Protein sequence:

>819_residues
MRWATILSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMADTNLDNDVLKARIGLLRDYDSLVTGDAHARDTLQH
LRRLADHDPALCQAIAALDADYTEKSLQRELFKSQNSLLSNSLAYFWSESSAQIRQGDDPAAARAASMLASAVQRLSLDT
TGEAVALARRRLDEAAQRTTSTPLLPHGRMLLKLLPETDTTIRRMRPIASLASYAQLKTYLQKQHACQQATARQVRFLLL
GLAVVMLGALLYLATLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLMRLAKWAKLPSARLGVVSVGADA
RIWPDPQDEAFRTMLAAVAATGPVAASDVLVVHANGTVEVLGKPERVRGAQWLCLRQHSEAATVALLCLRLPPLSARRDR
GLAAPAELLPQLHIALDTLFDALERRRLEDEARALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVTIALQQEQEPLHALGNPAQLQ
QVILNLASNAAQAMDMRGTVTIQLSAAKGSAADGTPRRIAQLRVSDHGIGIPPDQLDRIFDLFFTTRNRGTGLGLATVRK
IIDNHEGRIDVDSTLCVGTTFVVELPLRTGIAAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGLLEL
PAAVAMATSDPMRFDGVLLKRDRAGDAEHAIDALHAAAPKLPLILATRAMSLATRKGLGGAITEIIAQPFDLSALALALE
RALGRTMDMTTQDEGTPAL

Sequences:

>Translated_819_residues
MRWATILSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMADTNLDNDVLKARIGLLRDYDSLVTGDAHARDTLQH
LRRLADHDPALCQAIAALDADYTEKSLQRELFKSQNSLLSNSLAYFWSESSAQIRQGDDPAAARAASMLASAVQRLSLDT
TGEAVALARRRLDEAAQRTTSTPLLPHGRMLLKLLPETDTTIRRMRPIASLASYAQLKTYLQKQHACQQATARQVRFLLL
GLAVVMLGALLYLATLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLMRLAKWAKLPSARLGVVSVGADA
RIWPDPQDEAFRTMLAAVAATGPVAASDVLVVHANGTVEVLGKPERVRGAQWLCLRQHSEAATVALLCLRLPPLSARRDR
GLAAPAELLPQLHIALDTLFDALERRRLEDEARALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVTIALQQEQEPLHALGNPAQLQ
QVILNLASNAAQAMDMRGTVTIQLSAAKGSAADGTPRRIAQLRVSDHGIGIPPDQLDRIFDLFFTTRNRGTGLGLATVRK
IIDNHEGRIDVDSTLCVGTTFVVELPLRTGIAAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGLLEL
PAAVAMATSDPMRFDGVLLKRDRAGDAEHAIDALHAAAPKLPLILATRAMSLATRKGLGGAITEIIAQPFDLSALALALE
RALGRTMDMTTQDEGTPAL
>Mature_819_residues
MRWATILSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMADTNLDNDVLKARIGLLRDYDSLVTGDAHARDTLQH
LRRLADHDPALCQAIAALDADYTEKSLQRELFKSQNSLLSNSLAYFWSESSAQIRQGDDPAAARAASMLASAVQRLSLDT
TGEAVALARRRLDEAAQRTTSTPLLPHGRMLLKLLPETDTTIRRMRPIASLASYAQLKTYLQKQHACQQATARQVRFLLL
GLAVVMLGALLYLATLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLMRLAKWAKLPSARLGVVSVGADA
RIWPDPQDEAFRTMLAAVAATGPVAASDVLVVHANGTVEVLGKPERVRGAQWLCLRQHSEAATVALLCLRLPPLSARRDR
GLAAPAELLPQLHIALDTLFDALERRRLEDEARALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVTIALQQEQEPLHALGNPAQLQ
QVILNLASNAAQAMDMRGTVTIQLSAAKGSAADGTPRRIAQLRVSDHGIGIPPDQLDRIFDLFFTTRNRGTGLGLATVRK
IIDNHEGRIDVDSTLCVGTTFVVELPLRTGIAAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGLLEL
PAAVAMATSDPMRFDGVLLKRDRAGDAEHAIDALHAAAPKLPLILATRAMSLATRKGLGGAITEIIAQPFDLSALALALE
RALGRTMDMTTQDEGTPAL

Specific function: Activates virG, by phosphorylating it, in the presence of acetosyringone or hydroxysyringone [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=265, Percent_Identity=28.6792452830189, Blast_Score=103, Evalue=6e-23,
Organism=Escherichia coli, GI1788549, Length=238, Percent_Identity=32.3529411764706, Blast_Score=102, Evalue=9e-23,
Organism=Escherichia coli, GI145693157, Length=268, Percent_Identity=27.6119402985075, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790300, Length=247, Percent_Identity=29.9595141700405, Blast_Score=84, Evalue=5e-17,
Organism=Escherichia coli, GI48994928, Length=264, Percent_Identity=27.2727272727273, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI87081816, Length=366, Percent_Identity=27.0491803278689, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1786912, Length=303, Percent_Identity=27.3927392739274, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1788393, Length=233, Percent_Identity=29.6137339055794, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789149, Length=239, Percent_Identity=26.3598326359833, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 88772; Mature: 88772

Theoretical pI: Translated: 7.26; Mature: 7.26

Prosite motif: PS00059 ADH_ZINC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRWATILSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMADTNLDNDVLKARIGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LRDYDSLVTGDAHARDTLQHLRRLADHDPALCQAIAALDADYTEKSLQRELFKSQNSLLS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NSLAYFWSESSAQIRQGDDPAAARAASMLASAVQRLSLDTTGEAVALARRRLDEAAQRTT
HHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
STPLLPHGRMLLKLLPETDTTIRRMRPIASLASYAQLKTYLQKQHACQQATARQVRFLLL
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAVVMLGALLYLATLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLMRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AKWAKLPSARLGVVSVGADARIWPDPQDEAFRTMLAAVAATGPVAASDVLVVHANGTVEV
HHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEE
LGKPERVRGAQWLCLRQHSEAATVALLCLRLPPLSARRDRGLAAPAELLPQLHIALDTLF
CCCCHHHCCCCEEEEHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
DALERRRLEDEARALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCC
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
IALQQEQEPLHALGNPAQLQQVILNLASNAAQAMDMRGTVTIQLSAAKGSAADGTPRRIA
EEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHH
QLRVSDHGIGIPPDQLDRIFDLFFTTRNRGTGLGLATVRKIIDNHEGRIDVDSTLCVGTT
HHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEECCCCHHCCEE
FVVELPLRTGIAAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGLLEL
EEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHH
PAAVAMATSDPMRFDGVLLKRDRAGDAEHAIDALHAAAPKLPLILATRAMSLATRKGLGG
HHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
AITEIIAQPFDLSALALALERALGRTMDMTTQDEGTPAL
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRWATILSAVLLAGLIFFSLCMAALDRDTQRYGHALDALDALDMADTNLDNDVLKARIGL
CHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LRDYDSLVTGDAHARDTLQHLRRLADHDPALCQAIAALDADYTEKSLQRELFKSQNSLLS
HHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
NSLAYFWSESSAQIRQGDDPAAARAASMLASAVQRLSLDTTGEAVALARRRLDEAAQRTT
HHHHHHCCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCC
STPLLPHGRMLLKLLPETDTTIRRMRPIASLASYAQLKTYLQKQHACQQATARQVRFLLL
CCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLAVVMLGALLYLATLLRQRARVLRRRAEFDRLMVAVSRRLVANDRHQLDAGIEAGLMRL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHH
AKWAKLPSARLGVVSVGADARIWPDPQDEAFRTMLAAVAATGPVAASDVLVVHANGTVEV
HHHHCCCCCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCEEEE
LGKPERVRGAQWLCLRQHSEAATVALLCLRLPPLSARRDRGLAAPAELLPQLHIALDTLF
CCCCHHHCCCCEEEEHHCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
DALERRRLEDEARALEHRLELARRMETLGTMASGISHNFNNIVGAIRGNAEIALSKLDPH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCC
SPASEHLLEISHTTAHAYDLIESILSFGRVQNYNVQPVELNALLQGAVSLLSVSLPSTVT
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEE
IALQQEQEPLHALGNPAQLQQVILNLASNAAQAMDMRGTVTIQLSAAKGSAADGTPRRIA
EEEECCCCHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHH
QLRVSDHGIGIPPDQLDRIFDLFFTTRNRGTGLGLATVRKIIDNHEGRIDVDSTLCVGTT
HHEECCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCEECCCCHHCCEE
FVVELPLRTGIAAAPQAAPLPKTRSRHASLLLLCDDAAELDRLEEMLAALGHEPVGLLEL
EEEEECHHCCCCCCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCHHHH
PAAVAMATSDPMRFDGVLLKRDRAGDAEHAIDALHAAAPKLPLILATRAMSLATRKGLGG
HHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCH
AITEIIAQPFDLSALALALERALGRTMDMTTQDEGTPAL
HHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2796735; 2194232; 11743193; 11743194 [H]