Click here to switch to the map view.

The map label for this gene is ykoW [H]

Identifier: 84624227

GI number: 84624227

Start: 2863305

End: 2865374

Strand: Direct

Name: ykoW [H]

Synonym: XOO_2570

Alternate gene names: 84624227

Gene position: 2863305-2865374 (Clockwise)

Preceding gene: 84624226

Following gene: 84624229

Centisome position: 57.96

GC content: 63.33

Gene sequence:

>2070_bases
ATGCAAAAAGGCAAAGATCTCACCCTCCGCCTGATGATCGTCGACGACAGCGTGGAGAGTGCCGAGACCATCGTCACCGC
GCTGCGTAACGGCGGCATTGCGGTGCGCCCTTCGCGGCCGCAAAACCATGAGGAACTGGCCAACATGCTGTCGGGCCAGA
TCGATCTGGCCATCCTGGGTCAGGCGCAGCAAATCCCCATGAGCGCCCTGCAGACGCAGATCGCCGGCAGCGGCAATGAC
ATACCGGTCATCTTGCTGGCCGAGCGAATCGAAGAGAACGCCCTGGTCGAGGCCGCTTCGCATGGCGTGCGTGCCATTGC
CTTGCGTAACCGCCCCGCACACTTGCTCGCGCTGGTGCGCTCGGAATGGAACGACCTGCAGGCCCGTCGCGGGCTGCGCC
GCATCGAAGCGCAGATGCGCGAAACCGAGCGCCGCTGCGACGCCCTCATCGCGTCCTCGCGCGACCCGATCGCCTACGTG
CATGAAGGCATGCACATCCGCGCCAATGACGCCTATCTGGAAATGTTCGGCTTCGAGTCGTTCGACGATGTCGAAGGCAT
CTCGTTGCTGGACATGATCGCCGCGCAGTACGTCGACGATTTCAAACAGCTGCTCAAGGCGATGTCCAAGGGTGAGCCGC
CGCCGGCGCAGTACAAACTCGACGCGCGCCGCGTGGAAGGCGACACCTTCCCGGCCACGATGGAATTTGCCACCGCCACC
TACGAAGGCGAGCCGTGCATCCAGGTGGTGTTCCGCCGCCGGGAGGAGTTCGACCCGGAATTGGCACGCGAAGTCGAAGA
CCTGCGTCAACGCGACCAGGTCACCGGTCTACTCAATCGTCCTACCTTCATGGTGGCGCTGGAACAGGCCGTGGCGCAGG
CCGGTCGTAGCGAAGGCCAGTCGGGCTTCCTGTTGATCGAGCCGGATCATTACGCCCGCATCCTCCCGGAATTTGGCCTG
GATTCGGCCGATGCACTGATCGCCGCGCTCGCCGCGCATGTCGCCAGCGTGCTGGACGACAGCGTGGTTGCCGCACGCTT
CGGCGAACACAGTTTCGCCCTACTGATGAACGGCAATTACGCGCGCACGCACGCACTGGCGGAAATCGTGCGAGATGCGT
TCGCTCAGCACGTCTTCAGCGTGGGCGTGCGTTCGGCCACGGTGACGGTCAGCATCGGCGGCGTACAGATTGGCGAAAAG
ATCGCCAGTATTGGTCAGGTACTCAATCGCGGCACCGAAGCGGTGCGCACCACCGCCGAGCTCGGTGGCAATGCGATCAG
CATCTACGACCCGGCCGCGGCCGATCGGGCGGAAGAAGAACGGATAGAGCGCTGGGTCAAGCAGTTGCGCGAGGCCCTGG
TTGGCGACGGCTTCGTGCTGTATTACCAGCCGGTGCTCAATCTACAAGGCGAGCCGCTGGAGCTGTATCAGGCCTTCCTG
CGCCTGGAACGCAATGGCGAAATGATGTCGCCGAATGCGTTCATGGCGATTGCCGAAGAGCACGATCTGGTCACCGAGAT
CGACCGCTGGGTGGTGGCGCGCGCGATCCGGCAACTGGGCGAGCGGCAACGTGCCGGGCACAAGACGCACCTGCTGGTAC
GCATCGGGCCCAATTCGTTCTCCGACCCGCAGATGATCGACACCATCCGTGAGCAGTTGGCCGTGTACGGCGTGCCCGGT
GAACGGCTGTGGCTGCAGACGCCAGAGTCGAAGGTGTTTACCCATTTGCGCAACGCGCAGCAGTTCCTGAGCGCGGTGTC
GGCGATGGGCTGCAAGGTCGGGCTGGAACAGTTCGGGTCGGGCCTGGATTCGTTTCAGTTGCTGGCGCATTTCCAGCCCG
CCTTCCTCAAACTGGATCGCGGCATCACCGGCGACATCGCCTCGGCCCGGGAAAGCCAGGAGAAGATCCGCGAGATCACC
TCGCGCGCGCAGCCGGCCGGCATTTTGACAATGGCCGAATTCGTCGCCGATGCGCAGTCGATGAGCAGCTTCTTCACTGC
AGGCGTGGATTACGTACAGGGCGATTTCGTGGCACCGACCGGGCCGTTGATGAACTACGAGTTCGGCTGA

Upstream 100 bases:

>100_bases
TAAATATTGCTCCACATCTCACACTCGATGCGGCATGCTCCACACACGTGGACGCGCCCAACCCCTTGGTGTATTAAATC
CCGTCTCTAGGGAGCCGCAC

Downstream 100 bases:

>100_bases
GCCGGTACCGTTCCGCTCGTTCCACACTATCGCGCGACAACAAAAAACCCGCATTCCGCGGGTTTTTTGTTGTCTAAAAG
CGACGACCAACTCGACAACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 689; Mature: 689

Protein sequence:

>689_residues
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQNHEELANMLSGQIDLAILGQAQQIPMSALQTQIAGSGND
IPVILLAERIEENALVEAASHGVRAIALRNRPAHLLALVRSEWNDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANDAYLEMFGFESFDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEFGL
DSADALIAALAAHVASVLDDSVVAARFGEHSFALLMNGNYARTHALAEIVRDAFAQHVFSVGVRSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAISIYDPAAADRAEEERIERWVKQLREALVGDGFVLYYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLSAVSAMGCKVGLEQFGSGLDSFQLLAHFQPAFLKLDRGITGDIASARESQEKIREIT
SRAQPAGILTMAEFVADAQSMSSFFTAGVDYVQGDFVAPTGPLMNYEFG

Sequences:

>Translated_689_residues
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQNHEELANMLSGQIDLAILGQAQQIPMSALQTQIAGSGND
IPVILLAERIEENALVEAASHGVRAIALRNRPAHLLALVRSEWNDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANDAYLEMFGFESFDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEFGL
DSADALIAALAAHVASVLDDSVVAARFGEHSFALLMNGNYARTHALAEIVRDAFAQHVFSVGVRSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAISIYDPAAADRAEEERIERWVKQLREALVGDGFVLYYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLSAVSAMGCKVGLEQFGSGLDSFQLLAHFQPAFLKLDRGITGDIASARESQEKIREIT
SRAQPAGILTMAEFVADAQSMSSFFTAGVDYVQGDFVAPTGPLMNYEFG
>Mature_689_residues
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQNHEELANMLSGQIDLAILGQAQQIPMSALQTQIAGSGND
IPVILLAERIEENALVEAASHGVRAIALRNRPAHLLALVRSEWNDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYV
HEGMHIRANDAYLEMFGFESFDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQSGFLLIEPDHYARILPEFGL
DSADALIAALAAHVASVLDDSVVAARFGEHSFALLMNGNYARTHALAEIVRDAFAQHVFSVGVRSATVTVSIGGVQIGEK
IASIGQVLNRGTEAVRTTAELGGNAISIYDPAAADRAEEERIERWVKQLREALVGDGFVLYYQPVLNLQGEPLELYQAFL
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSFSDPQMIDTIREQLAVYGVPG
ERLWLQTPESKVFTHLRNAQQFLSAVSAMGCKVGLEQFGSGLDSFQLLAHFQPAFLKLDRGITGDIASARESQEKIREIT
SRAQPAGILTMAEFVADAQSMSSFFTAGVDYVQGDFVAPTGPLMNYEFG

Specific function: Probable signaling protein whose physiological role is not yet known [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=423, Percent_Identity=24.3498817966903, Blast_Score=113, Evalue=5e-26,
Organism=Escherichia coli, GI1788849, Length=242, Percent_Identity=26.0330578512397, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI87081921, Length=427, Percent_Identity=22.7166276346604, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=23.6286919831224, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1788381, Length=432, Percent_Identity=22.9166666666667, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI226510982, Length=436, Percent_Identity=23.8532110091743, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082096, Length=238, Percent_Identity=22.2689075630252, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1789650, Length=279, Percent_Identity=23.6559139784946, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081980, Length=242, Percent_Identity=26.0330578512397, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330
- InterPro:   IPR000014 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 76044; Mature: 76044

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQNHEELANMLSGQIDLAILG
CCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCEEEEEC
QAQQIPMSALQTQIAGSGNDIPVILLAERIEENALVEAASHGVRAIALRNRPAHLLALVR
CCHHCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
SEWNDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYVHEGMHIRANDAYLEMFGFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCEEEEECCCC
FDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCCHHHEEEE
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SGFLLIEPDHYARILPEFGLDSADALIAALAAHVASVLDDSVVAARFGEHSFALLMNGNY
CCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCH
ARTHALAEIVRDAFAQHVFSVGVRSATVTVSIGGVQIGEKIASIGQVLNRGTEAVRTTAE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGNAISIYDPAAADRAEEERIERWVKQLREALVGDGFVLYYQPVLNLQGEPLELYQAFL
HCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHH
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSF
HHHCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLSAVSAMGCKVGLEQFGS
CCCHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
GLDSFQLLAHFQPAFLKLDRGITGDIASARESQEKIREITSRAQPAGILTMAEFVADAQS
CCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MSSFFTAGVDYVQGDFVAPTGPLMNYEFG
HHHHHHHCHHHHCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQKGKDLTLRLMIVDDSVESAETIVTALRNGGIAVRPSRPQNHEELANMLSGQIDLAILG
CCCCCCEEEEEEEEECCHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHCCCCEEEEEC
QAQQIPMSALQTQIAGSGNDIPVILLAERIEENALVEAASHGVRAIALRNRPAHLLALVR
CCHHCCHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHCCEEEEEECCCCHHHHHHHH
SEWNDLQARRGLRRIEAQMRETERRCDALIASSRDPIAYVHEGMHIRANDAYLEMFGFES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCEEEECCCEEEEECCCC
FDDVEGISLLDMIAAQYVDDFKQLLKAMSKGEPPPAQYKLDARRVEGDTFPATMEFATAT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHCCCCCCCCCHHHEEEE
YEGEPCIQVVFRRREEFDPELAREVEDLRQRDQVTGLLNRPTFMVALEQAVAQAGRSEGQ
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
SGFLLIEPDHYARILPEFGLDSADALIAALAAHVASVLDDSVVAARFGEHSFALLMNGNY
CCEEEECCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCEEEEECCCH
ARTHALAEIVRDAFAQHVFSVGVRSATVTVSIGGVQIGEKIASIGQVLNRGTEAVRTTAE
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCHHHHHHHHHHHHHHHCCHHHHHHHHH
LGGNAISIYDPAAADRAEEERIERWVKQLREALVGDGFVLYYQPVLNLQGEPLELYQAFL
HCCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHCCCCCHHHHHHHHH
RLERNGEMMSPNAFMAIAEEHDLVTEIDRWVVARAIRQLGERQRAGHKTHLLVRIGPNSF
HHHCCCCEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCC
SDPQMIDTIREQLAVYGVPGERLWLQTPESKVFTHLRNAQQFLSAVSAMGCKVGLEQFGS
CCCHHHHHHHHHHHEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
GLDSFQLLAHFQPAFLKLDRGITGDIASARESQEKIREITSRAQPAGILTMAEFVADAQS
CCHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
MSSFFTAGVDYVQGDFVAPTGPLMNYEFG
HHHHHHHCHHHHCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 11728710 [H]