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The map label for this gene is gluQ

Identifier: 84624229

GI number: 84624229

Start: 2866450

End: 2867349

Strand: Direct

Name: gluQ

Synonym: XOO_2572

Alternate gene names: 84624229

Gene position: 2866450-2867349 (Clockwise)

Preceding gene: 84624227

Following gene: 84624230

Centisome position: 58.02

GC content: 71.33

Gene sequence:

>900_bases
ATGCCATCGCCCTCCTATCTCGGCCGCTTCGCGCCCTCGCCTACCGGCCCGCTGCACTTCGGCTCCCTGCTCGCTGCGTT
CGGCAGCTGGCTGCTCGCCCGGCATGCCGGCGGACAATGGTGCGTCCGCATCGAAGACATCGACCCGCCGCGCGCCGAAC
CCGGCGCTTCCGAACGGCAACTACGCACCCTGACCGCCTTCGGGCTGCACTCGGATCTTCCCGTGATCCGGCAGTCCGAG
CGCGACGCCGCCTACACTGCCGCCATCAACCGGCTGCTGGAGACCGGCCAGGCATTCGAGTGCAGCTGCAGCCGCGCAGA
CCTGGCCGGCATGGGCGGTATCCACCATGCCTGCGTCGCGCCACTCGGCGCGCGCCGTGCGGTGCGCCTGCGGGTGCCGC
CGCAATCGCCGGTCGGCTTCGACGACGCGCTGCACGGCCGCGTGCTGCAGGATGTCTACGCAGATGTGGGCGATGTGGTG
CTGCGCCGCGCCGATGGCTACTGGGCTTACCAACTGGCGGTGGTGGTGGACGATGCGGCGCAGGGCATCACCGATGTGGT
GCGCGGCGCCGACCTGCTCGACTCCACTCCGCGCCAGATGCTGCTGCAGCGCGCACTGGGCGTGCCGCAGCCGCGTTACC
TGCATCTGCCACTGATGCTGGATGGCGATGGCCGCAAGCTGTCCAAATCGCACGGCGCACCCGCGCTGGACGATACCGAC
CCACTGCCGGCCCTGCACGCCGCCTGGGCCGGGCTGGGCCAGCGCCCGGACGCGCTGCCGCGGCGCGCGACGGTCACGAC
CCTGCTGCAGCAGGCCGTGCGGCATTTTTCGCCGCAGTTGCTGCCGCGCCAACGCCAGCGGGACCGCGCTACCTGCGCAT
ACGAGCGCCAGCGTGACTAG

Upstream 100 bases:

>100_bases
CATGGCGCGATGGCTCCACGGATGCGGGGTGAACTGTTGCGGATCTGCGGGTGCGGCGGCTTGAAATCAAGCGAGCAGCT
GACCGACGATTCAGCTGCCC

Downstream 100 bases:

>100_bases
AATTGCGCCCCAGCACCGGCATCCAGGCGTGGCCGCGCCGGCACGCTCCTGGATCGCCCTCAGCCTTACTTGTTGATTGG
AGTCGTCATGACATCTCGCG

Product: aminoacyl-tRNA synthetase:glutamyl-like protein

Products: NA

Alternate protein names: Glu-Q-RSs

Number of amino acids: Translated: 299; Mature: 298

Protein sequence:

>299_residues
MPSPSYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGASERQLRTLTAFGLHSDLPVIRQSE
RDAAYTAAINRLLETGQAFECSCSRADLAGMGGIHHACVAPLGARRAVRLRVPPQSPVGFDDALHGRVLQDVYADVGDVV
LRRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMLLQRALGVPQPRYLHLPLMLDGDGRKLSKSHGAPALDDTD
PLPALHAAWAGLGQRPDALPRRATVTTLLQQAVRHFSPQLLPRQRQRDRATCAYERQRD

Sequences:

>Translated_299_residues
MPSPSYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGASERQLRTLTAFGLHSDLPVIRQSE
RDAAYTAAINRLLETGQAFECSCSRADLAGMGGIHHACVAPLGARRAVRLRVPPQSPVGFDDALHGRVLQDVYADVGDVV
LRRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMLLQRALGVPQPRYLHLPLMLDGDGRKLSKSHGAPALDDTD
PLPALHAAWAGLGQRPDALPRRATVTTLLQQAVRHFSPQLLPRQRQRDRATCAYERQRD
>Mature_298_residues
PSPSYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGASERQLRTLTAFGLHSDLPVIRQSER
DAAYTAAINRLLETGQAFECSCSRADLAGMGGIHHACVAPLGARRAVRLRVPPQSPVGFDDALHGRVLQDVYADVGDVVL
RRADGYWAYQLAVVVDDAAQGITDVVRGADLLDSTPRQMLLQRALGVPQPRYLHLPLMLDGDGRKLSKSHGAPALDDTDP
LPALHAAWAGLGQRPDALPRRATVTTLLQQAVRHFSPQLLPRQRQRDRATCAYERQRD

Specific function: Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble positi

COG id: COG0008

COG function: function code J; Glutamyl- and glutaminyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. GluQ subfamily

Homologues:

Organism=Homo sapiens, GI134288884, Length=257, Percent_Identity=36.5758754863813, Blast_Score=130, Evalue=2e-30,
Organism=Escherichia coli, GI226510925, Length=286, Percent_Identity=47.2027972027972, Blast_Score=231, Evalue=4e-62,
Organism=Escherichia coli, GI1788743, Length=247, Percent_Identity=36.8421052631579, Blast_Score=155, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI71993394, Length=249, Percent_Identity=32.9317269076305, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6324540, Length=264, Percent_Identity=35.6060606060606, Blast_Score=149, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24665321, Length=252, Percent_Identity=36.5079365079365, Blast_Score=145, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLUQ_XANOR (Q5GZ90)

Other databases:

- EMBL:   AE013598
- RefSeq:   YP_201366.1
- ProteinModelPortal:   Q5GZ90
- SMR:   Q5GZ90
- GeneID:   3262015
- GenomeReviews:   AE013598_GR
- KEGG:   xoo:XOO2727
- NMPDR:   fig|291331.3.peg.2849
- HOGENOM:   HBG628189
- OMA:   DWPRDPD
- ProtClustDB:   PRK05710
- BioCyc:   XORY291331:XOO2727-MONOMER
- GO:   GO:0005737
- GO:   GO:0006412
- HAMAP:   MF_01428
- InterPro:   IPR022380
- InterPro:   IPR000924
- InterPro:   IPR020058
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR10119
- PRINTS:   PR00987
- TIGRFAMs:   TIGR03838

Pfam domain/function: PF00749 tRNA-synt_1c

EC number: NA

Molecular weight: Translated: 32599; Mature: 32468

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 45-45 BINDING 170-170 BINDING 188-188 BINDING 229-229

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSPSYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGASERQ
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHH
LRTLTAFGLHSDLPVIRQSERDAAYTAAINRLLETGQAFECSCSRADLAGMGGIHHACVA
HHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHCCCCHHHHHHC
PLGARRAVRLRVPPQSPVGFDDALHGRVLQDVYADVGDVVLRRADGYWAYQLAVVVDDAA
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHH
QGITDVVRGADLLDSTPRQMLLQRALGVPQPRYLHLPLMLDGDGRKLSKSHGAPALDDTD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHCCCCCCCCCCC
PLPALHAAWAGLGQRPDALPRRATVTTLLQQAVRHFSPQLLPRQRQRDRATCAYERQRD
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
PSPSYLGRFAPSPTGPLHFGSLLAAFGSWLLARHAGGQWCVRIEDIDPPRAEPGASERQ
CCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHH
LRTLTAFGLHSDLPVIRQSERDAAYTAAINRLLETGQAFECSCSRADLAGMGGIHHACVA
HHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHCCCCEECCCCCCCHHCCCCHHHHHHC
PLGARRAVRLRVPPQSPVGFDDALHGRVLQDVYADVGDVVLRRADGYWAYQLAVVVDDAA
CCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEECHHH
QGITDVVRGADLLDSTPRQMLLQRALGVPQPRYLHLPLMLDGDGRKLSKSHGAPALDDTD
HHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCEEEEEEEECCCCCCHHHCCCCCCCCCCC
PLPALHAAWAGLGQRPDALPRRATVTTLLQQAVRHFSPQLLPRQRQRDRATCAYERQRD
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA