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The map label for this gene is ntrC [H]

Identifier: 84624104

GI number: 84624104

Start: 2719364

End: 2720848

Strand: Direct

Name: ntrC [H]

Synonym: XOO_2447

Alternate gene names: 84624104

Gene position: 2719364-2720848 (Clockwise)

Preceding gene: 84624103

Following gene: 84624105

Centisome position: 55.05

GC content: 65.99

Gene sequence:

>1485_bases
ATGAGTGAGTCCCGCATTCTGTTGATCGACAGTGACGCCGTGCGCGCCGAGCGCACCGTGTCGCTGCTCGAATTTATGGA
CTTCAATCCCCGCTGGGTCACCGACGGCGCCGATATCAATCCTGGCCGTCACCGCCACGATGAGTGGATGGCGGTGATGG
TGGGCTCGGCGCAGGACGCTGCACAGGCCGACAAATTCTTCGACTGGCTGGCCGATGCCAAGTTGCCGCCGCCCGTGCTG
CTGATGGAGGGCAGCCCGACCGCGTTCGCGCAAGCGCACGGCCTGCACGAAGCCAATGTCTGGGCATTGGACACCCCCCT
GCGTCATGCGCAGCTGGAAGCCCTGCTGCGCCGTGCAAGCCTCAAGCGGCTGGATGCCGAGCATCAGGCCGGCGTGCAGC
AGGATTCGGGCCCGACCGGCAATAGCGAAGCGGTGACCCGCCTGCGCCGGCTGATCGACCAGGTGGCTGCGTTCGACACC
ACCGTGCTGGTGCTGGGCGAATCCGGTACCGGCAAAGAAGTCGTGGCACGCGCCATCCACCAGCATTCGCCGCGACGCGA
CGGGCCGTTCGTCGCAATCAATTGCGGCGCGATTCCGCCGGATCTGCTGGAAAGCGAATTGTTCGGCCACGAAAAAGGCG
CCTTCACCGGCGCGCTGACCACCCGCAAGGGCCGCTTCGAAATGGCCGAAGGCGGCACGCTGCTGCTGGACGAAATCGGC
GACATGAGCCTGCCGATGCAGGTCAAGCTGCTGCGCGTGCTGCAGGAACGCAGCTTCGAGCGCGTCGGCGGCGGGCAGAC
CATCCGCTGCAACGTGCGCGTGATCGCCGCGACGCACCGCAACCTGGAAACCCGCATCAGCGATGGCCAGTTCCGCGAGG
ACCTGTTCTATCGCCTCAACGTGTTTCCGATCGAAATGCCGGCGCTGCGCGAACGCGTGGACGATCTGGCCATGCTGGTG
CAGACGATTGCGGGCCAACTGGCACGCACCGGACGCGGCGAAGTGCGCTTCGCCGAAGAAGCCCTGCAGGCGCTGCGCAG
CTACAACTGGCCAGGCAACGTACGCGAGCTCACCAATCTGGTGGAGCGCCTGGCGGTGCTGCATCCGGGTGGGCTGGTGC
GGGTGCAGGATCTGCCGGCGCGGTATCGCGGCGATTTCGCCTCGGCCATCCTGGTCGAGTTGCCGCCGGAACCGGCACTG
CTGGCCGCGCCGGTCGAAGTCACCGACCTACCAAGCAACGTGGTGACGCTGCAGCCCAAGACGGCCGATGCCGAACCGGC
CACGGCTGCCAGCTTGCCGGATGACGGTATCGATTTGCGTGGCCACATGGCCAACATCGAGCTGGCGTTGATCAACGAAG
CACTGGAACGCACCCAGGGCGTGGTGGCGCATGCCGCCCAACTGCTCGGCCTGCGCCGTACCACATTGGTGGAGAAGCTG
CGCAAGTACGGCATCGACCGCGAGCAGACCGAGCTGGCCAACTGA

Upstream 100 bases:

>100_bases
AACACGCTCTTCGCGCGGGTGCTGACAATTTTGTCAGCAAGCTGTCCTATATCCAGGAAGTCATGCCAATCCTGGAGGGC
CTGACGGTAAGGAGCCAGGA

Downstream 100 bases:

>100_bases
GCGGTCACACGCTCCGCTTGCGCTCGCTGGCATAGCGCTTGCTTCAGCAGGATCACGCCCTTTGCAGCCGACGGCTGCGG
CGAAATCCCGACCTTCACCA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 494; Mature: 493

Protein sequence:

>494_residues
MSESRILLIDSDAVRAERTVSLLEFMDFNPRWVTDGADINPGRHRHDEWMAVMVGSAQDAAQADKFFDWLADAKLPPPVL
LMEGSPTAFAQAHGLHEANVWALDTPLRHAQLEALLRRASLKRLDAEHQAGVQQDSGPTGNSEAVTRLRRLIDQVAAFDT
TVLVLGESGTGKEVVARAIHQHSPRRDGPFVAINCGAIPPDLLESELFGHEKGAFTGALTTRKGRFEMAEGGTLLLDEIG
DMSLPMQVKLLRVLQERSFERVGGGQTIRCNVRVIAATHRNLETRISDGQFREDLFYRLNVFPIEMPALRERVDDLAMLV
QTIAGQLARTGRGEVRFAEEALQALRSYNWPGNVRELTNLVERLAVLHPGGLVRVQDLPARYRGDFASAILVELPPEPAL
LAAPVEVTDLPSNVVTLQPKTADAEPATAASLPDDGIDLRGHMANIELALINEALERTQGVVAHAAQLLGLRRTTLVEKL
RKYGIDREQTELAN

Sequences:

>Translated_494_residues
MSESRILLIDSDAVRAERTVSLLEFMDFNPRWVTDGADINPGRHRHDEWMAVMVGSAQDAAQADKFFDWLADAKLPPPVL
LMEGSPTAFAQAHGLHEANVWALDTPLRHAQLEALLRRASLKRLDAEHQAGVQQDSGPTGNSEAVTRLRRLIDQVAAFDT
TVLVLGESGTGKEVVARAIHQHSPRRDGPFVAINCGAIPPDLLESELFGHEKGAFTGALTTRKGRFEMAEGGTLLLDEIG
DMSLPMQVKLLRVLQERSFERVGGGQTIRCNVRVIAATHRNLETRISDGQFREDLFYRLNVFPIEMPALRERVDDLAMLV
QTIAGQLARTGRGEVRFAEEALQALRSYNWPGNVRELTNLVERLAVLHPGGLVRVQDLPARYRGDFASAILVELPPEPAL
LAAPVEVTDLPSNVVTLQPKTADAEPATAASLPDDGIDLRGHMANIELALINEALERTQGVVAHAAQLLGLRRTTLVEKL
RKYGIDREQTELAN
>Mature_493_residues
SESRILLIDSDAVRAERTVSLLEFMDFNPRWVTDGADINPGRHRHDEWMAVMVGSAQDAAQADKFFDWLADAKLPPPVLL
MEGSPTAFAQAHGLHEANVWALDTPLRHAQLEALLRRASLKRLDAEHQAGVQQDSGPTGNSEAVTRLRRLIDQVAAFDTT
VLVLGESGTGKEVVARAIHQHSPRRDGPFVAINCGAIPPDLLESELFGHEKGAFTGALTTRKGRFEMAEGGTLLLDEIGD
MSLPMQVKLLRVLQERSFERVGGGQTIRCNVRVIAATHRNLETRISDGQFREDLFYRLNVFPIEMPALRERVDDLAMLVQ
TIAGQLARTGRGEVRFAEEALQALRSYNWPGNVRELTNLVERLAVLHPGGLVRVQDLPARYRGDFASAILVELPPEPALL
AAPVEVTDLPSNVVTLQPKTADAEPATAASLPDDGIDLRGHMANIELALINEALERTQGVVAHAAQLLGLRRTTLVEKLR
KYGIDREQTELAN

Specific function: Member of the two-component regulatory system ntrB/ntrC involved in the activation of nitrogen assimilatory genes such as glnA. NtrC is phosphorylated by ntrB and interacts with sigma-54 [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI87082117, Length=348, Percent_Identity=47.4137931034483, Blast_Score=283, Evalue=1e-77,
Organism=Escherichia coli, GI1788550, Length=421, Percent_Identity=39.9049881235154, Blast_Score=272, Evalue=4e-74,
Organism=Escherichia coli, GI1790299, Length=415, Percent_Identity=40.9638554216867, Blast_Score=264, Evalue=1e-71,
Organism=Escherichia coli, GI1789087, Length=352, Percent_Identity=43.1818181818182, Blast_Score=263, Evalue=1e-71,
Organism=Escherichia coli, GI1790437, Length=408, Percent_Identity=40.1960784313725, Blast_Score=261, Evalue=5e-71,
Organism=Escherichia coli, GI1788905, Length=341, Percent_Identity=42.5219941348974, Blast_Score=247, Evalue=1e-66,
Organism=Escherichia coli, GI1789233, Length=347, Percent_Identity=42.3631123919308, Blast_Score=233, Evalue=2e-62,
Organism=Escherichia coli, GI87082152, Length=229, Percent_Identity=51.528384279476, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1786524, Length=242, Percent_Identity=48.3471074380165, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI87081872, Length=351, Percent_Identity=36.7521367521368, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787583, Length=397, Percent_Identity=34.2569269521411, Blast_Score=184, Evalue=8e-48,
Organism=Escherichia coli, GI1789828, Length=358, Percent_Identity=31.8435754189944, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI87081858, Length=344, Percent_Identity=29.9418604651163, Blast_Score=137, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR010114
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 54340; Mature: 54208

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESRILLIDSDAVRAERTVSLLEFMDFNPRWVTDGADINPGRHRHDEWMAVMVGSAQDA
CCCCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEECCCHHH
AQADKFFDWLADAKLPPPVLLMEGSPTAFAQAHGLHEANVWALDTPLRHAQLEALLRRAS
HHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHH
LKRLDAEHQAGVQQDSGPTGNSEAVTRLRRLIDQVAAFDTTVLVLGESGTGKEVVARAIH
HHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
QHSPRRDGPFVAINCGAIPPDLLESELFGHEKGAFTGALTTRKGRFEMAEGGTLLLDEIG
HCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCEEEEECCC
DMSLPMQVKLLRVLQERSFERVGGGQTIRCNVRVIAATHRNLETRISDGQFREDLFYRLN
CCCCCHHHHHHHHHHHHCHHHCCCCCEEEEEEEEEEEECCCCHHHCCCCHHHHHHHEEEE
VFPIEMPALRERVDDLAMLVQTIAGQLARTGRGEVRFAEEALQALRSYNWPGNVRELTNL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCHHHHHHH
VERLAVLHPGGLVRVQDLPARYRGDFASAILVELPPEPALLAAPVEVTDLPSNVVTLQPK
HHHHHHCCCCCEEEEECCCCHHCCCCCCEEEEECCCCCCEEECCCEEECCCCCEEEECCC
TADAEPATAASLPDDGIDLRGHMANIELALINEALERTQGVVAHAAQLLGLRRTTLVEKL
CCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKYGIDREQTELAN
HHHCCCHHHHHCCC
>Mature Secondary Structure 
SESRILLIDSDAVRAERTVSLLEFMDFNPRWVTDGADINPGRHRHDEWMAVMVGSAQDA
CCCEEEEEECCCHHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCEEEEEECCCHHH
AQADKFFDWLADAKLPPPVLLMEGSPTAFAQAHGLHEANVWALDTPLRHAQLEALLRRAS
HHHHHHHHHHHCCCCCCCEEEECCCCCHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHH
LKRLDAEHQAGVQQDSGPTGNSEAVTRLRRLIDQVAAFDTTVLVLGESGTGKEVVARAIH
HHHHCCHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHH
QHSPRRDGPFVAINCGAIPPDLLESELFGHEKGAFTGALTTRKGRFEMAEGGTLLLDEIG
HCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCEEEEECCC
DMSLPMQVKLLRVLQERSFERVGGGQTIRCNVRVIAATHRNLETRISDGQFREDLFYRLN
CCCCCHHHHHHHHHHHHCHHHCCCCCEEEEEEEEEEEECCCCHHHCCCCHHHHHHHEEEE
VFPIEMPALRERVDDLAMLVQTIAGQLARTGRGEVRFAEEALQALRSYNWPGNVRELTNL
EEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHCCCCCCCHHHHHHH
VERLAVLHPGGLVRVQDLPARYRGDFASAILVELPPEPALLAAPVEVTDLPSNVVTLQPK
HHHHHHCCCCCEEEEECCCCHHCCCCCCEEEEECCCCCCEEECCCEEECCCCCEEEECCC
TADAEPATAASLPDDGIDLRGHMANIELALINEALERTQGVVAHAAQLLGLRRTTLVEKL
CCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKYGIDREQTELAN
HHHCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2881918; 11481430; 8478331 [H]