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The map label for this gene is hutI

Identifier: 84623934

GI number: 84623934

Start: 2533914

End: 2535119

Strand: Direct

Name: hutI

Synonym: XOO_2277

Alternate gene names: 84623934

Gene position: 2533914-2535119 (Clockwise)

Preceding gene: 84623931

Following gene: 84623935

Centisome position: 51.29

GC content: 67.83

Gene sequence:

>1206_bases
ATGCATTGCGACGTTCTCTGGCACAACGCGCAACTGATGACCCTGGATGCCGCCGACGGCGGCCTGGGCATCGTGGACGA
CGGCACCGTCGCCTGCCAGCAGGGCCGCATCGTCTACGCCGGCCCGGCCGCACAGGCACCAGCACTGCAGCCACACGCCA
CGCACGACTGCCAGCGTCGCTGGATCAGCCCGGGTCTGATCGATTGCCATACCCATCTGGTGTACGCCGGCAATCGCGCC
AACGAATTCGAGCAACGCCTGCGCGGTGCCAGCTACGCCGACATCGCCGCAGCTGGCGGTGGCATCGTGGCGACGGTGCG
CGCCACCCGCGCCGCCGACGACGCGGCACTGCTGGCCGCCAGCCTGCCGCGCCTGGACGCGATGCTTGGCGAAGGTGTGA
CCACGCTGGAAATCAAATCCGGCTACGGGCTCACGCTGGACGATGAAATCAAGCAACTGCGCGTGGCGCGCCAACTCGCC
GCGCTGCGCAAGGTGGAAGTGGTGCCGACCTTCCTCGGCGCACATGCAGTGCCGCCTGGCGGCGATGCGCAGCGCTACAC
CGACCAGGTCTGCACGCAGATGATTCCGGCGATCGCCGCGCAAGGGCTGGCCGAGGCCGTGGACGTATTCTGCGAGCATC
TGGCGTTCTCGCACGCGCAGGCCGAACAGGTCTTCATCGCGGCGCAAGCGCATGGCTTGCACATCAAGATCCACGCCGAA
CAGCTGAGCAATCAGCACGGTGCCGAACTGGCTGCACGCTACGGCGCGTTGTCGGCCGATCACATCGAATACCTGGACCA
GGCCGGCATCGCAGCGATGGCTGGCGCCGGCACGGTGGCAGTGCTGTTGCCGGGCGCGTTTTATTTCACTCGCGACACCC
AGGTGCCGCCGATTGCCGCATTGCGCGCGGCCGGCGTGCCACTGGCGCTGGCCACCGACTGCAACCCAGGCACTTCGCCG
CTGACCAGCCCGCTGCTGGCGATGAACATGGCGGCGACGCTGTTCCGCATGACCGTGGACGAATGCATCGCCGGCTTCAC
CCGCGAGGCTGCGCGCGCGCTCGGGCGCAGCGAGCGCCTGGGCCGGTTGCGCGCCGGCATGGACTGCGATCTGGCGATCT
GGGACATCGATGCGCCGGCCGATCTGGTCTACCGCATGGGCTTCAACCCTCTTCATGCCCGCGTGTTGCGCGGGCATCTT
TGCTGA

Upstream 100 bases:

>100_bases
CCCGGGCGGCCCAGAACACCTGCATCTGTTGGTCAGCCACTGGACACCCTCGATTGCCGAACTTATTGTATATACATATC
AGACACCACGAGCCTGCGCC

Downstream 100 bases:

>100_bases
ATCCGGAGTCGTCATGCCTGTTTCTGTTGTCTTGCAGCCCGGCCAGGTCACACTGACGCAATGGCGTGCGCTGTATCGCG
GTGCCGAGGTCGCAGTGGAC

Product: imidazolonepropionase

Products: NA

Alternate protein names: Imidazolone-5-propionate hydrolase

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MHCDVLWHNAQLMTLDAADGGLGIVDDGTVACQQGRIVYAGPAAQAPALQPHATHDCQRRWISPGLIDCHTHLVYAGNRA
NEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEIKQLRVARQLA
ALRKVEVVPTFLGAHAVPPGGDAQRYTDQVCTQMIPAIAAQGLAEAVDVFCEHLAFSHAQAEQVFIAAQAHGLHIKIHAE
QLSNQHGAELAARYGALSADHIEYLDQAGIAAMAGAGTVAVLLPGAFYFTRDTQVPPIAALRAAGVPLALATDCNPGTSP
LTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGRLRAGMDCDLAIWDIDAPADLVYRMGFNPLHARVLRGHL
C

Sequences:

>Translated_401_residues
MHCDVLWHNAQLMTLDAADGGLGIVDDGTVACQQGRIVYAGPAAQAPALQPHATHDCQRRWISPGLIDCHTHLVYAGNRA
NEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEIKQLRVARQLA
ALRKVEVVPTFLGAHAVPPGGDAQRYTDQVCTQMIPAIAAQGLAEAVDVFCEHLAFSHAQAEQVFIAAQAHGLHIKIHAE
QLSNQHGAELAARYGALSADHIEYLDQAGIAAMAGAGTVAVLLPGAFYFTRDTQVPPIAALRAAGVPLALATDCNPGTSP
LTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGRLRAGMDCDLAIWDIDAPADLVYRMGFNPLHARVLRGHL
C
>Mature_401_residues
MHCDVLWHNAQLMTLDAADGGLGIVDDGTVACQQGRIVYAGPAAQAPALQPHATHDCQRRWISPGLIDCHTHLVYAGNRA
NEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAASLPRLDAMLGEGVTTLEIKSGYGLTLDDEIKQLRVARQLA
ALRKVEVVPTFLGAHAVPPGGDAQRYTDQVCTQMIPAIAAQGLAEAVDVFCEHLAFSHAQAEQVFIAAQAHGLHIKIHAE
QLSNQHGAELAARYGALSADHIEYLDQAGIAAMAGAGTVAVLLPGAFYFTRDTQVPPIAALRAAGVPLALATDCNPGTSP
LTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERLGRLRAGMDCDLAIWDIDAPADLVYRMGFNPLHARVLRGHL
C

Specific function: Unknown

COG id: COG1228

COG function: function code Q; Imidazolonepropionase and related amidohydrolases

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hutI family

Homologues:

Organism=Homo sapiens, GI223972677, Length=337, Percent_Identity=36.7952522255193, Blast_Score=193, Evalue=2e-49,
Organism=Caenorhabditis elegans, GI17555004, Length=342, Percent_Identity=34.7953216374269, Blast_Score=197, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HUTI_XANOR (Q5H071)

Other databases:

- EMBL:   AE013598
- RefSeq:   YP_201035.6
- HSSP:   Q8U8Z6
- ProteinModelPortal:   Q5H071
- SMR:   Q5H071
- GeneID:   3261538
- GenomeReviews:   AE013598_GR
- KEGG:   xoo:XOO2396
- NMPDR:   fig|291331.3.peg.4363
- ProtClustDB:   PRK09356
- BioCyc:   XORY291331:XOO2396-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00372
- InterPro:   IPR006680
- InterPro:   IPR005920
- InterPro:   IPR011059
- TIGRFAMs:   TIGR01224

Pfam domain/function: PF01979 Amidohydro_1; SSF51338 Metalo_hydrolase

EC number: =3.5.2.7

Molecular weight: Translated: 42426; Mature: 42426

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: BINDING 557-557 BINDING 570-570 BINDING 620-620 BINDING 653-653 BINDING 719-719

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHCDVLWHNAQLMTLDAADGGLGIVDDGTVACQQGRIVYAGPAAQAPALQPHATHDCQRR
CCCEEEEECCEEEEEECCCCCEEEECCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHH
WISPGLIDCHTHLVYAGNRANEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAA
HCCCCEEECEEEEEEECCCHHHHHHHHCCCCCHHHHHCCCCEEEEEEHHCCCCHHHHHHH
SLPRLDAMLGEGVTTLEIKSGYGLTLDDEIKQLRVARQLAALRKVEVVPTFLGAHAVPPG
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDAQRYTDQVCTQMIPAIAAQGLAEAVDVFCEHLAFSHAQAEQVFIAAQAHGLHIKIHAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEHH
QLSNQHGAELAARYGALSADHIEYLDQAGIAAMAGAGTVAVLLPGAFYFTRDTQVPPIAA
HHCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCEEEEEECCEEEEECCCCCCCHHH
LRAAGVPLALATDCNPGTSPLTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERL
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GRLRAGMDCDLAIWDIDAPADLVYRMGFNPLHARVLRGHLC
HHHHCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHCCCC
>Mature Secondary Structure
MHCDVLWHNAQLMTLDAADGGLGIVDDGTVACQQGRIVYAGPAAQAPALQPHATHDCQRR
CCCEEEEECCEEEEEECCCCCEEEECCCCEEEECCEEEEECCCCCCCCCCCCCCHHHHHH
WISPGLIDCHTHLVYAGNRANEFEQRLRGASYADIAAAGGGIVATVRATRAADDAALLAA
HCCCCEEECEEEEEEECCCHHHHHHHHCCCCCHHHHHCCCCEEEEEEHHCCCCHHHHHHH
SLPRLDAMLGEGVTTLEIKSGYGLTLDDEIKQLRVARQLAALRKVEVVPTFLGAHAVPPG
HHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GDAQRYTDQVCTQMIPAIAAQGLAEAVDVFCEHLAFSHAQAEQVFIAAQAHGLHIKIHAE
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEEEHH
QLSNQHGAELAARYGALSADHIEYLDQAGIAAMAGAGTVAVLLPGAFYFTRDTQVPPIAA
HHCCCHHHHHHHHHCCCCHHHHHHHHHCCHHHHCCCCEEEEEECCEEEEECCCCCCCHHH
LRAAGVPLALATDCNPGTSPLTSPLLAMNMAATLFRMTVDECIAGFTREAARALGRSERL
HHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GRLRAGMDCDLAIWDIDAPADLVYRMGFNPLHARVLRGHLC
HHHHCCCCCCEEEEECCCCHHHHHHCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA