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The map label for this gene is dcp [H]

Identifier: 84623877

GI number: 84623877

Start: 2459321

End: 2460550

Strand: Direct

Name: dcp [H]

Synonym: XOO_2220

Alternate gene names: 84623877

Gene position: 2459321-2460550 (Clockwise)

Preceding gene: 84623875

Following gene: 84623878

Centisome position: 49.78

GC content: 61.63

Gene sequence:

>1230_bases
ATGCCGTCCTACAGCATCGCCGCACCCACCAGCACGCAGGCCGCTACCCAAGCCAACCCCTTCTTTGCCGACAGCACGCT
GCCGCTGCATTACCCGCCGTTCGACAAGATCATCGACAGCGATTTCGCACCCGCCTTCGATGTCGGCATGGCCGAGCAAT
TGAAGGAAGTGGAAAAAATCGCCAACCAGAACGCCAAGCCGAGCTTCGACAACACCATCGTCGCGCTGGAAAAGAGCGGC
AGCACGCTCGACCGCGCCACCACGGTATTCTTCAATCTGGTCGGTGCCGACACCAACGACGCACGCAAGAAGCTGCAGGC
CGACTACTCGGCCAGGTTTGCAGCGCACCGCGATGCGATTTCGCTCAACGGCAAGCTGTTCGCGCGCATCCAGACCTTGT
ACGACCAACGCACCAAGCTGGGCCTGGATGCGCAAGGCGTGCGCCTGGTCGAGAAGTACGACAGCGACTTCGTGCGCGAC
GGCGCCAAGCTCTCCGACGCCGACAAGACCACGCTCAAGGCAATGAACGCCGAGCCGGCCAACCTGGGCACCACCTTCAG
CCAGAACGTACTGGCAGAAGTGAATGCCGCCGCCGTCGTGGTCGATGAGCTCAAGCAACTGGACGGCTTGTCGGAGGAGC
AGATCGCCGCTGCCGCCGAAGCCGCCAAGGCACGCAACCTCGACGGCAAATACGTCATCGCGCTGCTCAATACCACCGGC
CAACCGCCGCTGACTCAGCTGAAGAATCGCGAGCTGCGCAAGAAGATCTACAACGCTTCGGTGTCGCACGGCAGCCACGG
CGGCCAGTACGACAACACCGCGCTGGTGGCGCGCATCATGAAGCTGCGTGCCGACAAGGCCAAGCTGCTCGGCTTCCCCA
CCTACGCAGTCTATCGGCTGGAAAACCAGACCGCCAAGACGCCCGAAGCGGTCAACGCGATGCTGGGCAAACTGGCGCCG
GCTGCGGTGGCCAATGCCAAGCGCGAAGCCGCCGATCTGCAGGCCATGATCGACAAGGAACAAAAGGCCGCGCGCAAGCC
GACCTTCAAGCTGGAAGCCTGGGATTGGGCCTACTACAGCGAGAAGGTGCGCCAGGCCAATTACAACTTCGACCAATCGC
AGGTCAAGCCCTACTTCGAGTTGAAGAACGTGCTGGAAAACGGCGTTTTCTATGCAGCCAATCAGGAATACGGCCTGACC
TTCAAGCAGCGTACCGACCTGCCGACCTAG

Upstream 100 bases:

>100_bases
TGTCCCGCGTGGCTGGATTAGCCTCGGCGGTTCGCACTTTGGAGCAACGCTCTTGACCACCCGTCTCGCTTTTGCCCTGG
CCGCTTCCCTGGGACTCGCC

Downstream 100 bases:

>100_bases
CGCGACGACATCACCGTCTACGACATGTTCGACGCCGACGGCAAGCAGTTGGCGATCTTCATCGCCGACATGTATGCGCG
CCAATCCAAGCGCGGTGGCG

Product: putative peptidyl-dipeptidase

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MPSYSIAAPTSTQAATQANPFFADSTLPLHYPPFDKIIDSDFAPAFDVGMAEQLKEVEKIANQNAKPSFDNTIVALEKSG
STLDRATTVFFNLVGADTNDARKKLQADYSARFAAHRDAISLNGKLFARIQTLYDQRTKLGLDAQGVRLVEKYDSDFVRD
GAKLSDADKTTLKAMNAEPANLGTTFSQNVLAEVNAAAVVVDELKQLDGLSEEQIAAAAEAAKARNLDGKYVIALLNTTG
QPPLTQLKNRELRKKIYNASVSHGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAVYRLENQTAKTPEAVNAMLGKLAP
AAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYSEKVRQANYNFDQSQVKPYFELKNVLENGVFYAANQEYGLT
FKQRTDLPT

Sequences:

>Translated_409_residues
MPSYSIAAPTSTQAATQANPFFADSTLPLHYPPFDKIIDSDFAPAFDVGMAEQLKEVEKIANQNAKPSFDNTIVALEKSG
STLDRATTVFFNLVGADTNDARKKLQADYSARFAAHRDAISLNGKLFARIQTLYDQRTKLGLDAQGVRLVEKYDSDFVRD
GAKLSDADKTTLKAMNAEPANLGTTFSQNVLAEVNAAAVVVDELKQLDGLSEEQIAAAAEAAKARNLDGKYVIALLNTTG
QPPLTQLKNRELRKKIYNASVSHGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAVYRLENQTAKTPEAVNAMLGKLAP
AAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYSEKVRQANYNFDQSQVKPYFELKNVLENGVFYAANQEYGLT
FKQRTDLPT
>Mature_408_residues
PSYSIAAPTSTQAATQANPFFADSTLPLHYPPFDKIIDSDFAPAFDVGMAEQLKEVEKIANQNAKPSFDNTIVALEKSGS
TLDRATTVFFNLVGADTNDARKKLQADYSARFAAHRDAISLNGKLFARIQTLYDQRTKLGLDAQGVRLVEKYDSDFVRDG
AKLSDADKTTLKAMNAEPANLGTTFSQNVLAEVNAAAVVVDELKQLDGLSEEQIAAAAEAAKARNLDGKYVIALLNTTGQ
PPLTQLKNRELRKKIYNASVSHGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAVYRLENQTAKTPEAVNAMLGKLAPA
AVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYSEKVRQANYNFDQSQVKPYFELKNVLENGVFYAANQEYGLTF
KQRTDLPT

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=285, Percent_Identity=25.6140350877193, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI14149738, Length=296, Percent_Identity=27.027027027027, Blast_Score=79, Evalue=7e-15,
Organism=Escherichia coli, GI1787819, Length=394, Percent_Identity=43.9086294416244, Blast_Score=348, Evalue=4e-97,
Organism=Escherichia coli, GI1789913, Length=392, Percent_Identity=28.3163265306122, Blast_Score=126, Evalue=3e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 45009; Mature: 44878

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSYSIAAPTSTQAATQANPFFADSTLPLHYPPFDKIIDSDFAPAFDVGMAEQLKEVEKI
CCCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHCCHHHHHHHHHHH
ANQNAKPSFDNTIVALEKSGSTLDRATTVFFNLVGADTNDARKKLQADYSARFAAHRDAI
HCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCE
SLNGKLFARIQTLYDQRTKLGLDAQGVRLVEKYDSDFVRDGAKLSDADKTTLKAMNAEPA
ECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHCCCCCC
NLGTTFSQNVLAEVNAAAVVVDELKQLDGLSEEQIAAAAEAAKARNLDGKYVIALLNTTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
QPPLTQLKNRELRKKIYNASVSHGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAVYRL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEE
ENQTAKTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
EKVRQANYNFDQSQVKPYFELKNVLENGVFYAANQEYGLTFKQRTDLPT
HHHHHCCCCCCHHHCCHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCC
>Mature Secondary Structure 
PSYSIAAPTSTQAATQANPFFADSTLPLHYPPFDKIIDSDFAPAFDVGMAEQLKEVEKI
CCCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCHHHHHCCCCCCHHHCCHHHHHHHHHHH
ANQNAKPSFDNTIVALEKSGSTLDRATTVFFNLVGADTNDARKKLQADYSARFAAHRDAI
HCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHCCCE
SLNGKLFARIQTLYDQRTKLGLDAQGVRLVEKYDSDFVRDGAKLSDADKTTLKAMNAEPA
ECCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCHHHHHCCCCCCCCCHHHHHHCCCCCC
NLGTTFSQNVLAEVNAAAVVVDELKQLDGLSEEQIAAAAEAAKARNLDGKYVIALLNTTG
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCC
QPPLTQLKNRELRKKIYNASVSHGSHGGQYDNTALVARIMKLRADKAKLLGFPTYAVYRL
CCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHCCCCCEEEEEE
ENQTAKTPEAVNAMLGKLAPAAVANAKREAADLQAMIDKEQKAARKPTFKLEAWDWAYYS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCHHHHH
EKVRQANYNFDQSQVKPYFELKNVLENGVFYAANQEYGLTFKQRTDLPT
HHHHHCCCCCCHHHCCHHHHHHHHHHCCEEEEECCCCCCEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]