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The map label for this gene is dcp [H]

Identifier: 84623878

GI number: 84623878

Start: 2460575

End: 2461447

Strand: Direct

Name: dcp [H]

Synonym: XOO_2221

Alternate gene names: 84623878

Gene position: 2460575-2461447 (Clockwise)

Preceding gene: 84623877

Following gene: 84623882

Centisome position: 49.81

GC content: 61.51

Gene sequence:

>873_bases
ATGTTCGACGCCGACGGCAAGCAGTTGGCGATCTTCATCGCCGACATGTATGCGCGCCAATCCAAGCGCGGTGGCGCATG
GATGAACGCCTATGTGTCGCAGTCCGAGCTGACCGGATTCAAGCCGGTGGTGGCCAATCACCTCAACATCCCCAAACCGC
CGGCCGGCCAGCCCACGCTGCTGACCTGGGACGAAGTGACCACCATGTTCCATGAGTTCGGGCATGCGTTGCACGGCATG
TTCTCCGACGTCAAATACCCGTATTTCTCCGGCACCAGCGTGCCGCGCGACTTCGTCGAGTTTCCCTCGCAGGTCAACGA
AATGTGGGCCGACGAACCATCCATCCTGAAGCACGACGCCAAGCATTATCAGAACGGCTCGCCGATGCCGCAGGCATTGC
TGGACAAGGTGATTGCCACGTCCAAGTTCAACCAGGGCTTTGCCACCACCGAGTATCTGGGTGCGGCGATGCTGGATCAG
AACTGGCATCAGGTCAGCGCCAACCAGGTGCCGGACGCCGCCGGCGTGATGGCCTTCGAAGCCAAGGCGCTGCAGCAGGA
CGGCATTGCCTATGCGCCGGTGCCGCAGCGCTACAAGACCCCGTATTTCAGCCACATCATGGGCGGTTACGCGGCAGGCT
ATTACGCCTACATCTGGTCGGAAGTGCTGGACGCCAACACCCAGCAGTGGTTCAAGCAGCACGGTGGCCTGAGCCGCGCC
AATGGCGATCGTTTCCGCAAGACCCTGCTCTCGCGCGGCGGTAGCGTGGATGCAATGGAGCTGTTCCAGAACTTCGCCGG
GCATGCGCCGCAGATCGAGCCGCTGCTCGAAAAGCGTGGCCTGACCGAGACAGCGGAAACGCCAAAACGCTAA

Upstream 100 bases:

>100_bases
GGAAAACGGCGTTTTCTATGCAGCCAATCAGGAATACGGCCTGACCTTCAAGCAGCGTACCGACCTGCCGACCTAGCGCG
ACGACATCACCGTCTACGAC

Downstream 100 bases:

>100_bases
GTGCACTCCGGCGGGCGATGACGCATCGTTCGCTCGTCTGCTATCGACGCGCGCTCCCCTTTCCCGCCTGTGGGAGACGG
GCATCCAGCAGATACAACGG

Product: hypothetical protein

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 290; Mature: 290

Protein sequence:

>290_residues
MFDADGKQLAIFIADMYARQSKRGGAWMNAYVSQSELTGFKPVVANHLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGM
FSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKHDAKHYQNGSPMPQALLDKVIATSKFNQGFATTEYLGAAMLDQ
NWHQVSANQVPDAAGVMAFEAKALQQDGIAYAPVPQRYKTPYFSHIMGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRA
NGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLTETAETPKR

Sequences:

>Translated_290_residues
MFDADGKQLAIFIADMYARQSKRGGAWMNAYVSQSELTGFKPVVANHLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGM
FSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKHDAKHYQNGSPMPQALLDKVIATSKFNQGFATTEYLGAAMLDQ
NWHQVSANQVPDAAGVMAFEAKALQQDGIAYAPVPQRYKTPYFSHIMGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRA
NGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLTETAETPKR
>Mature_290_residues
MFDADGKQLAIFIADMYARQSKRGGAWMNAYVSQSELTGFKPVVANHLNIPKPPAGQPTLLTWDEVTTMFHEFGHALHGM
FSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKHDAKHYQNGSPMPQALLDKVIATSKFNQGFATTEYLGAAMLDQ
NWHQVSANQVPDAAGVMAFEAKALQQDGIAYAPVPQRYKTPYFSHIMGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRA
NGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLTETAETPKR

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=283, Percent_Identity=35.3356890459364, Blast_Score=155, Evalue=4e-38,
Organism=Homo sapiens, GI14149738, Length=282, Percent_Identity=34.7517730496454, Blast_Score=144, Evalue=7e-35,
Organism=Homo sapiens, GI156105687, Length=234, Percent_Identity=29.4871794871795, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1787819, Length=283, Percent_Identity=48.7632508833922, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1789913, Length=287, Percent_Identity=39.7212543554007, Blast_Score=198, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6319793, Length=276, Percent_Identity=30.7971014492754, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6322715, Length=250, Percent_Identity=28.8, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI20129717, Length=224, Percent_Identity=29.0178571428571, Blast_Score=111, Evalue=6e-25,
Organism=Drosophila melanogaster, GI21356111, Length=304, Percent_Identity=24.6710526315789, Blast_Score=94, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 32366; Mature: 32366

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDADGKQLAIFIADMYARQSKRGGAWMNAYVSQSELTGFKPVVANHLNIPKPPAGQPTL
CCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCE
LTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKHDA
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
KHYQNGSPMPQALLDKVIATSKFNQGFATTEYLGAAMLDQNWHQVSANQVPDAAGVMAFE
HHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHH
AKALQQDGIAYAPVPQRYKTPYFSHIMGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRA
HHHHHHCCCEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
NGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLTETAETPKR
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MFDADGKQLAIFIADMYARQSKRGGAWMNAYVSQSELTGFKPVVANHLNIPKPPAGQPTL
CCCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCE
LTWDEVTTMFHEFGHALHGMFSDVKYPYFSGTSVPRDFVEFPSQVNEMWADEPSILKHDA
EEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
KHYQNGSPMPQALLDKVIATSKFNQGFATTEYLGAAMLDQNWHQVSANQVPDAAGVMAFE
HHHCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHCCCCCCCCHHHHHHHH
AKALQQDGIAYAPVPQRYKTPYFSHIMGGYAAGYYAYIWSEVLDANTQQWFKQHGGLSRA
HHHHHHCCCEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCC
NGDRFRKTLLSRGGSVDAMELFQNFAGHAPQIEPLLEKRGLTETAETPKR
CHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]