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The map label for this gene is ruvB [H]

Identifier: 84623204

GI number: 84623204

Start: 1704035

End: 1705072

Strand: Direct

Name: ruvB [H]

Synonym: XOO_1547

Alternate gene names: 84623204

Gene position: 1704035-1705072 (Clockwise)

Preceding gene: 84623203

Following gene: 84623205

Centisome position: 34.49

GC content: 65.7

Gene sequence:

>1038_bases
ATGGACCAGCGCATCATCGCCAGCAGCTCCACCCGCGAAGACGATGCCGCCGATGCGAGCATTCGTCCCAAGCGTTTGGC
CGATTATCTCGGCCAGCAGCCGGTGCGCGAGCAGATGGAGATCTACATCCAGGCGGCCAAGGCGCGCGGCGAGGCGATGG
ATCATGTGCTGATCTTCGGCCCGCCCGGGTTGGGCAAGACCACGCTCAGCCACGTCATCGCCAACGAGTTGGGCGTGAGC
CTGCGCGTGACCTCCGGCCCGGTGATCGAAAAGGCCGGCGATCTGGCCGCGCTGCTGACCAACCTGCAGCCGCACGATGT
GTTGTTCATCGACGAAATCCACCGCCTCTCGCCGGTGGTGGAAGAAGTGCTGTACCCGGCGATGGAAGATTTCCAGATCG
ACATCATGATCGGCGACGGCCCGGCCGCGCGTTCGATCAAGATCGATTTGCCGCCGTTCACCCTGATCGGCGCCACCACC
CGTGCCGGGTTGCTGACCGCGCCACTGCGCGACCGCTTCGGCATCGTGCAGCGGCTGGAGTTCTATTCGCCGCAGGAGCT
GACCCGCATCGTGATCCGCTCGGCGGCAATTCTAGGCATCGACTGCACGCCCGAGGGCGCTGCGGAAATCGCACGCCGCG
CGCGTGGAACCCCGCGTATCGCCAACCGGCTGTTGCGCCGCGTGCGCGACTACGCCCAGGTCAAGGCGGCCGGGCATATC
GATTTGCCGGTGGCGCAGGCGGCCATGCAGATGCTCAAGGTCGACCCGGAAGGGTTCGACGAGCTCGACCGTCGCATGTT
GCGCACCATCGTCGAGCATTTCGATGGCGGCCCAGTCGGTGTTGAATCGCTCGCCGCCTCGCTGTCGGAAGAGCGGGGCA
CGCTGGAAGACGTGATCGAACCCTATCTGATCCAGCAGGGCTTTCTGATCCGCACCGCGCGCGGCCGCATGGTCACCACC
AAGGCCTATCTGCATCTGGGCCTGAAGCCGCCGCGCGACCGCGCTCCGGGCATCGGCGAACCGGGAGACTTGTTCTGA

Upstream 100 bases:

>100_bases
GCTGGAGATTCGGGATTGGTAAGCGCGTAGCGCTGAACGCGCCCGCGTCCGATACTATTCGGTTCCAATTCCCGCTCCCG
AATCTTCCACTCCCGCTCTC

Downstream 100 bases:

>100_bases
TGACGCTGCGTTCGTTGCTCGCCTGGGGCATTTCGATCGACATTCCTGGCTCATGACCACCGCATCCCGCATCCCACATC
CCGCATCCCCGTCCATATTC

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 345; Mature: 345

Protein sequence:

>345_residues
MDQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVS
LRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATT
RAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTT
KAYLHLGLKPPRDRAPGIGEPGDLF

Sequences:

>Translated_345_residues
MDQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVS
LRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATT
RAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTT
KAYLHLGLKPPRDRAPGIGEPGDLF
>Mature_345_residues
MDQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFGPPGLGKTTLSHVIANELGVS
LRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVVEEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATT
RAGLLTAPLRDRFGIVQRLEFYSPQELTRIVIRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIEPYLIQQGFLIRTARGRMVTT
KAYLHLGLKPPRDRAPGIGEPGDLF

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family [H]

Homologues:

Organism=Escherichia coli, GI1788167, Length=328, Percent_Identity=69.2073170731707, Blast_Score=471, Evalue=1e-134,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- ProDom:   PD005323 [H]

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 37845; Mature: 37845

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFG
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
PPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVV
CCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
EEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRLE
HHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCEEECCHHHHHHHHHHHH
FYSPQELTRIVIRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
HCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIE
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHH
PYLIQQGFLIRTARGRMVTTKAYLHLGLKPPRDRAPGIGEPGDLF
HHHHHCCCEEEECCCCEEEEEEHEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDQRIIASSSTREDDAADASIRPKRLADYLGQQPVREQMEIYIQAAKARGEAMDHVLIFG
CCCCEECCCCCCCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCEEEEEC
PPGLGKTTLSHVIANELGVSLRVTSGPVIEKAGDLAALLTNLQPHDVLFIDEIHRLSPVV
CCCCCHHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
EEVLYPAMEDFQIDIMIGDGPAARSIKIDLPPFTLIGATTRAGLLTAPLRDRFGIVQRLE
HHHHHCCCCCEEEEEEECCCCCCCEEEEECCCEEEEECCHHCCEEECCHHHHHHHHHHHH
FYSPQELTRIVIRSAAILGIDCTPEGAAEIARRARGTPRIANRLLRRVRDYAQVKAAGHI
HCCHHHHHHHHHHHHHEEEECCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
DLPVAQAAMQMLKVDPEGFDELDRRMLRTIVEHFDGGPVGVESLAASLSEERGTLEDVIE
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHH
PYLIQQGFLIRTARGRMVTTKAYLHLGLKPPRDRAPGIGEPGDLF
HHHHHCCCEEEECCCCEEEEEEHEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]