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The map label for this gene is gpmA [H]

Identifier: 84623019

GI number: 84623019

Start: 1485003

End: 1485752

Strand: Direct

Name: gpmA [H]

Synonym: XOO_1362

Alternate gene names: 84623019

Gene position: 1485003-1485752 (Clockwise)

Preceding gene: 84623015

Following gene: 84623020

Centisome position: 30.06

GC content: 64.4

Gene sequence:

>750_bases
GTGACCCGCAAACTCGTACTGCTGCGCCATGGCCAGAGCCAATGGAATCTGGACAACCGTTTCACCGGCTGGGTGGATGT
GGAACTCACCGACCAGGGCCGCCAGGAAGCTGTGGCGGCCGGCAAGCTGATGAAGGACGAAGGGCTGCAGTTCGATGTCG
CCCACACCTCGGTGCTCAAGCGCGCCATCCACACGCTGCAGGGCGCGTTGAAGGAACTCGACCAGGACTGGTTGCCGGTG
TCCAAGAGCTGGCGCCTCAACGAGCGCCACTACGGCGGCCTGCAAGGCCTGGACAAGGCCGAAACCGCGGCCAAGCACGG
CGAGGAGCAGGTCAAGATCTGGCGCCGTTCGTACGACATCCCGCCGCCGGCGATGGACGTCGACGACCCGGGGCACCCGT
GTCACGACCGTCGCTACGCCACGCTCGATCGCAATGCGTTGCCGGGCACCGAGTCGCTGGCGACCACGCTGGTGCGCGTG
TTGCCGTATTGGCACGACGCGATTGCGCCGCAGTTGAAGGCCGGGCAGACCGTGCTGGTGACCGCGCACGGCAACTCGCT
GCGTGCGCTATACAAGTACCTCAACGATGTCTCCAACGAACAGATTCTGGAGCTCAATATCCCCACCGGCATCCCGCTGT
TGTTCGAGCTGGACGACAATCTGCAGGTGCGCAGCTTCCGTTATCTGGGCGATCCGGAAGCGGCCAAGCGTGCGGCCGAG
GCAGTAGCCAACCAGGGCAAGGCGAAGTAA

Upstream 100 bases:

>100_bases
CATAGCATCGCGCGTTGTCCGTGGCGATCTCGTGCACGCCTGCGATGCACGCGCTGCCGCTACAATCGCAGGCTGATCGG
CCCCCAATCGGAGAACCGTA

Downstream 100 bases:

>100_bases
ACGCCGCTGATGGTTGCAGCGCTGCGTGCGTCGCGCGCAGCGCCTGTCTTCGTGTGGCACGCGGCTGCAACGCGCCGCGT
GCTGCGTTGAATGGAAGCGG

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-dependent PGAM; PGAM; Phosphoglyceromutase; dPGM [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MTRKLVLLRHGQSQWNLDNRFTGWVDVELTDQGRQEAVAAGKLMKDEGLQFDVAHTSVLKRAIHTLQGALKELDQDWLPV
SKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVDDPGHPCHDRRYATLDRNALPGTESLATTLVRV
LPYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDVSNEQILELNIPTGIPLLFELDDNLQVRSFRYLGDPEAAKRAAE
AVANQGKAK

Sequences:

>Translated_249_residues
MTRKLVLLRHGQSQWNLDNRFTGWVDVELTDQGRQEAVAAGKLMKDEGLQFDVAHTSVLKRAIHTLQGALKELDQDWLPV
SKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVDDPGHPCHDRRYATLDRNALPGTESLATTLVRV
LPYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDVSNEQILELNIPTGIPLLFELDDNLQVRSFRYLGDPEAAKRAAE
AVANQGKAK
>Mature_248_residues
TRKLVLLRHGQSQWNLDNRFTGWVDVELTDQGRQEAVAAGKLMKDEGLQFDVAHTSVLKRAIHTLQGALKELDQDWLPVS
KSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDIPPPAMDVDDPGHPCHDRRYATLDRNALPGTESLATTLVRVL
PYWHDAIAPQLKAGQTVLVTAHGNSLRALYKYLNDVSNEQILELNIPTGIPLLFELDDNLQVRSFRYLGDPEAAKRAAEA
VANQGKAK

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI50593010, Length=251, Percent_Identity=56.1752988047809, Blast_Score=299, Evalue=2e-81,
Organism=Homo sapiens, GI4505753, Length=249, Percent_Identity=57.429718875502, Blast_Score=285, Evalue=2e-77,
Organism=Homo sapiens, GI71274132, Length=249, Percent_Identity=55.421686746988, Blast_Score=272, Evalue=3e-73,
Organism=Homo sapiens, GI4502445, Length=251, Percent_Identity=49.003984063745, Blast_Score=254, Evalue=6e-68,
Organism=Homo sapiens, GI40353764, Length=251, Percent_Identity=49.003984063745, Blast_Score=254, Evalue=6e-68,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=59.6273291925466, Blast_Score=185, Evalue=4e-47,
Organism=Escherichia coli, GI1786970, Length=246, Percent_Identity=61.7886178861789, Blast_Score=315, Evalue=2e-87,
Organism=Saccharomyces cerevisiae, GI6322697, Length=244, Percent_Identity=56.9672131147541, Blast_Score=271, Evalue=5e-74,
Organism=Saccharomyces cerevisiae, GI6324516, Length=302, Percent_Identity=33.4437086092715, Blast_Score=145, Evalue=5e-36,
Organism=Saccharomyces cerevisiae, GI6320183, Length=299, Percent_Identity=31.438127090301, Blast_Score=139, Evalue=5e-34,
Organism=Saccharomyces cerevisiae, GI6324857, Length=108, Percent_Identity=32.4074074074074, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24646216, Length=250, Percent_Identity=54.4, Blast_Score=290, Evalue=5e-79,
Organism=Drosophila melanogaster, GI85725270, Length=250, Percent_Identity=54.8, Blast_Score=267, Evalue=6e-72,
Organism=Drosophila melanogaster, GI85725272, Length=250, Percent_Identity=54.8, Blast_Score=267, Evalue=6e-72,
Organism=Drosophila melanogaster, GI24650981, Length=250, Percent_Identity=54.8, Blast_Score=267, Evalue=6e-72,
Organism=Drosophila melanogaster, GI28571815, Length=251, Percent_Identity=38.6454183266932, Blast_Score=170, Evalue=8e-43,
Organism=Drosophila melanogaster, GI28571817, Length=251, Percent_Identity=38.6454183266932, Blast_Score=170, Evalue=8e-43,
Organism=Drosophila melanogaster, GI24648979, Length=251, Percent_Identity=38.6454183266932, Blast_Score=170, Evalue=1e-42,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 27986; Mature: 27855

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS00175 PG_MUTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRKLVLLRHGQSQWNLDNRFTGWVDVELTDQGRQEAVAAGKLMKDEGLQFDVAHTSVLK
CCCEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHH
RAIHTLQGALKELDQDWLPVSKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCC
PPPAMDVDDPGHPCHDRRYATLDRNALPGTESLATTLVRVLPYWHDAIAPQLKAGQTVLV
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEE
TAHGNSLRALYKYLNDVSNEQILELNIPTGIPLLFELDDNLQVRSFRYLGDPEAAKRAAE
EECCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHH
AVANQGKAK
HHHHCCCCC
>Mature Secondary Structure 
TRKLVLLRHGQSQWNLDNRFTGWVDVELTDQGRQEAVAAGKLMKDEGLQFDVAHTSVLK
CCEEEEEECCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCEEEHHHHHHHH
RAIHTLQGALKELDQDWLPVSKSWRLNERHYGGLQGLDKAETAAKHGEEQVKIWRRSYDI
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCHHHHHHHHHHCCC
PPPAMDVDDPGHPCHDRRYATLDRNALPGTESLATTLVRVLPYWHDAIAPQLKAGQTVLV
CCCCCCCCCCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHCCCCEEEE
TAHGNSLRALYKYLNDVSNEQILELNIPTGIPLLFELDDNLQVRSFRYLGDPEAAKRAAE
EECCCHHHHHHHHHHCCCCCEEEEEECCCCCEEEEEECCCCEEEEEEECCCHHHHHHHHH
AVANQGKAK
HHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]