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The map label for this gene is map

Identifier: 84490276

GI number: 84490276

Start: 1677956

End: 1678933

Strand: Direct

Name: map

Synonym: Msp_1496

Alternate gene names: 84490276

Gene position: 1677956-1678933 (Clockwise)

Preceding gene: 84490273

Following gene: 84490278

Centisome position: 94.94

GC content: 32.41

Gene sequence:

>978_bases
ATGTTTGAAAAATATGAAAAAGCAGGAAAAATTGCATCAAAAGTTAGAAAAGAGGCTGTAAAGAAAATTACTGCAGGTAT
GAAAGTAATTGATCTTGTGGAGTGGATTGAATCAGAAATTAAAAGTACTGGTGCTGGATTATCTTTCCCATGTAATGTTT
CTATCAACCAAATAGCTGCTCATTATACTTCTGCTCCTAGTGATGATACACGATTTTGTTATGGTGATATTGTAAAGATT
GATCTTGGAGCTGAAGTTGATGGTTATATTTCTGATACTGCTGTTACTGTTATTGTTGAGGGCGATAATGGAGAACTTGT
TGATGAGGAGGGTAAAGCTTATAATATGCCAGGTCGATTAGATGATGGTAATCCTGTTGTTAGCGAGGATGAAATTGAAG
AAAGACATGCTATTATTAATGCTTCTAGTTGTGCATTAGAAAATGCTATTAGTATTATAAAAGAGGGAGTTACTTTAAAT
GAAATTGGTTACGAAGTTCAAAAAACTATGAATGATCTTGGATATAATCCTATTGTTAATCTTACTGGCCATAGTTTAGA
GCAGAATAATTTACATGCTGGTCTTTCCATTCCTAATTATCCAGATGGTAGTAATCATGAGTTAAAAGAGGGAGATCATA
TTGCTGTTGAACCTTTTGCTACTAATGGTGTTGGTTTGGTAAATGATATTCCCCAGCATTATATTTATTCTTTCCTTAGA
AATAGGCCTATGAGACAACCTGATTCTAAACATTTACTTAATTATATTGGAAATAATTTATGTTATTTCCCTTTTGCTAG
AAGACATTTACTTGAAGTTTATGATGAACATAGATTAAATAGGGCTATACGTCCTTTAATTTCTTCTAGATCTATTTATC
CATACAATGCTTTGAAAGAAAAAACTGATGGTATGGTTGCTCAGACTGAGCATACTATTATTGTTGAAAAGGATGGATGT
TGTGTTACTACTTTGTAA

Upstream 100 bases:

>100_bases
ATTATTTATCTAATTAATTATACTTTTATAAGAGTATATATTTAAATTAATAAATATAGTAAAAATATAATTAGTTTTAA
AAATTTAGACCGTGATATTA

Downstream 100 bases:

>100_bases
CACTTATTTTTTTTATTCTTGTGTTTTCCATCCTGCTATTGCACATTGTCCCATTGATACACTTCCATCTCCTGGACATG
TTTGTTTGTGTTGTATGTAT

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MFEKYEKAGKIASKVRKEAVKKITAGMKVIDLVEWIESEIKSTGAGLSFPCNVSINQIAAHYTSAPSDDTRFCYGDIVKI
DLGAEVDGYISDTAVTVIVEGDNGELVDEEGKAYNMPGRLDDGNPVVSEDEIEERHAIINASSCALENAISIIKEGVTLN
EIGYEVQKTMNDLGYNPIVNLTGHSLEQNNLHAGLSIPNYPDGSNHELKEGDHIAVEPFATNGVGLVNDIPQHYIYSFLR
NRPMRQPDSKHLLNYIGNNLCYFPFARRHLLEVYDEHRLNRAIRPLISSRSIYPYNALKEKTDGMVAQTEHTIIVEKDGC
CVTTL

Sequences:

>Translated_325_residues
MFEKYEKAGKIASKVRKEAVKKITAGMKVIDLVEWIESEIKSTGAGLSFPCNVSINQIAAHYTSAPSDDTRFCYGDIVKI
DLGAEVDGYISDTAVTVIVEGDNGELVDEEGKAYNMPGRLDDGNPVVSEDEIEERHAIINASSCALENAISIIKEGVTLN
EIGYEVQKTMNDLGYNPIVNLTGHSLEQNNLHAGLSIPNYPDGSNHELKEGDHIAVEPFATNGVGLVNDIPQHYIYSFLR
NRPMRQPDSKHLLNYIGNNLCYFPFARRHLLEVYDEHRLNRAIRPLISSRSIYPYNALKEKTDGMVAQTEHTIIVEKDGC
CVTTL
>Mature_325_residues
MFEKYEKAGKIASKVRKEAVKKITAGMKVIDLVEWIESEIKSTGAGLSFPCNVSINQIAAHYTSAPSDDTRFCYGDIVKI
DLGAEVDGYISDTAVTVIVEGDNGELVDEEGKAYNMPGRLDDGNPVVSEDEIEERHAIINASSCALENAISIIKEGVTLN
EIGYEVQKTMNDLGYNPIVNLTGHSLEQNNLHAGLSIPNYPDGSNHELKEGDHIAVEPFATNGVGLVNDIPQHYIYSFLR
NRPMRQPDSKHLLNYIGNNLCYFPFARRHLLEVYDEHRLNRAIRPLISSRSIYPYNALKEKTDGMVAQTEHTIIVEKDGC
CVTTL

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI5803092, Length=324, Percent_Identity=31.7901234567901, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI124494254, Length=289, Percent_Identity=23.8754325259516, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17544396, Length=326, Percent_Identity=30.9815950920245, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17542840, Length=338, Percent_Identity=23.9644970414201, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6319380, Length=330, Percent_Identity=28.7878787878788, Blast_Score=117, Evalue=2e-27,
Organism=Drosophila melanogaster, GI17137568, Length=324, Percent_Identity=27.7777777777778, Blast_Score=113, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24658585, Length=343, Percent_Identity=23.9067055393586, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002468
- InterPro:   IPR018349
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 36073; Mature: 36073

Theoretical pI: Translated: 4.85; Mature: 4.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKYEKAGKIASKVRKEAVKKITAGMKVIDLVEWIESEIKSTGAGLSFPCNVSINQIAA
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
HYTSAPSDDTRFCYGDIVKIDLGAEVDGYISDTAVTVIVEGDNGELVDEEGKAYNMPGRL
HHCCCCCCCCEEEECCEEEEEECCCCCCEECCEEEEEEEECCCCCEECCCCCEECCCCCC
DDGNPVVSEDEIEERHAIINASSCALENAISIIKEGVTLNEIGYEVQKTMNDLGYNPIVN
CCCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEE
LTGHSLEQNNLHAGLSIPNYPDGSNHELKEGDHIAVEPFATNGVGLVNDIPQHYIYSFLR
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
NRPMRQPDSKHLLNYIGNNLCYFPFARRHLLEVYDEHRLNRAIRPLISSRSIYPYNALKE
CCCCCCCCHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
KTDGMVAQTEHTIIVEKDGCCVTTL
HHCCCEEECCEEEEEECCCCEEECC
>Mature Secondary Structure
MFEKYEKAGKIASKVRKEAVKKITAGMKVIDLVEWIESEIKSTGAGLSFPCNVSINQIAA
CCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHH
HYTSAPSDDTRFCYGDIVKIDLGAEVDGYISDTAVTVIVEGDNGELVDEEGKAYNMPGRL
HHCCCCCCCCEEEECCEEEEEECCCCCCEECCEEEEEEEECCCCCEECCCCCEECCCCCC
DDGNPVVSEDEIEERHAIINASSCALENAISIIKEGVTLNEIGYEVQKTMNDLGYNPIVN
CCCCCCCCHHHHHHHHHEECCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEEE
LTGHSLEQNNLHAGLSIPNYPDGSNHELKEGDHIAVEPFATNGVGLVNDIPQHYIYSFLR
CCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHH
NRPMRQPDSKHLLNYIGNNLCYFPFARRHLLEVYDEHRLNRAIRPLISSRSIYPYNALKE
CCCCCCCCHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHH
KTDGMVAQTEHTIIVEKDGCCVTTL
HHCCCEEECCEEEEEECCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]