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The map label for this gene is fae-hps

Identifier: 84490278

GI number: 84490278

Start: 1681475

End: 1682695

Strand: Direct

Name: fae-hps

Synonym: Msp_1498

Alternate gene names: 84490278

Gene position: 1681475-1682695 (Clockwise)

Preceding gene: 84490276

Following gene: 84490280

Centisome position: 95.14

GC content: 33.5

Gene sequence:

>1221_bases
ATGTCTGATATATATGAGATAGGTGAAGCTTTAATTGGTGATGGACCTGAATTAGCACATATTGATCTTATAGTTGGTAG
TAAACAAGGACCTGTTGGTACTGCTTTTGCAACTAACATGGCAAGTATGAGTGTTGGTCATACTCCTTTATTATCTGTTA
TTAGACCAAACTTACCTACTAAACCTGCTACTCTTATTGTACCTAAAGTAACTGTACAAAATCTAGATGATGCAAGTAAA
ATATTTGGTCCAGCTCAAACTGCTGTTGGTCGTGCTGTAGCAGATGCTGTTGAAGAAGAAATAATTCCAAAGGATATTGT
GGAAGATATTGTATTGATGGTTAATGTATTTATTGATCCTTCTGCTAAGGATTACCGTAAAATATACCAATACAATTATG
GTGCTACTAAATTAGCTATTAAACGTGCATTTGATAAATATCCTTCTGTTGATAAGGTTTTAGCTGAAAAAGACAGAGGA
ACACATCCAATTATGGGATTCAAAGCTATGAAATTATGGAACCCACCTTACTTACAAGTTGCATTAGATCTTGATAATGA
AGATAGAATGCGTAGTATTATAAGAGATTTACCTAAACGTGAAAGAATTCTTATTGAAGCAGGTACACCTTTAGTTAAAA
AATTTGGTGTTGAAATTATCAGTAAAATAAGAGAAGAAAGACCGGGTGCTTTCATTATTGCTGATCTTAAAACTTTAGAC
GTTGGTAGAGTAGAAGTTAAAATGGCTGCTGATGAAACAGCTGATGCTGTTGCTATTTCTGGTCTTGGAACCAATGAATC
CATTGAGAAAGCTATCCATGAATGTTCTAAACAAGGAATTTACTCTATTCTTGATATGATGAATGTAAGTGATATTCCTT
CCAAACTTGAAGAACTTAAATTAAAACCTAATATAGTTTTATTACACAGAAATATTGATTCTGAGACTATGAGAGATAAT
GATGGTGAACAACAATCTGAATGGGGTAACATCAAAGATATTAAATCTAAACTTGGTAAACGAGGTTTAATTGCTGTTGC
TGGTGGAGTAACTCCTGAAAAAGTTGATACTGCCTTAGCTAATGGTGCTAATATTATTATTGCTGGAAGATATATTATTG
GTTCATCTGATGTTAGAAGAGCTGCTGAAGATTTCCTCAGATACTTACCTCAAGATTCTGATACAATGAGATTAGCTCTC
GATGAGGATGAAAAAATTTAG

Upstream 100 bases:

>100_bases
AAATATATAAATATAATATTATTGAAAAACTTTTTTTTATAATTCATACATCTTGTGATGGAAAAAAGATTATAATTGAA
TAAAATGGAGAATATAATTA

Downstream 100 bases:

>100_bases
ATTTTCTTTTTTTTTCTTCTTTTTATTTTTTGTAATTGTTTTTGTATAGTTGAATTTATTTTTTAGTATATGTTATAAGT
TATTTGTAATAAGTTATAAG

Product: bifunctional formaldehyde-activating enzyme/3-hexulose-6-phosphate synthase

Products: NA

Alternate protein names: Formaldehyde-activating enzyme; Fae; 3-hexulose-6-phosphate synthase; HPS; D-arabino-3-hexulose-6-phosphate formaldehyde lyase

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MSDIYEIGEALIGDGPELAHIDLIVGSKQGPVGTAFATNMASMSVGHTPLLSVIRPNLPTKPATLIVPKVTVQNLDDASK
IFGPAQTAVGRAVADAVEEEIIPKDIVEDIVLMVNVFIDPSAKDYRKIYQYNYGATKLAIKRAFDKYPSVDKVLAEKDRG
THPIMGFKAMKLWNPPYLQVALDLDNEDRMRSIIRDLPKRERILIEAGTPLVKKFGVEIISKIREERPGAFIIADLKTLD
VGRVEVKMAADETADAVAISGLGTNESIEKAIHECSKQGIYSILDMMNVSDIPSKLEELKLKPNIVLLHRNIDSETMRDN
DGEQQSEWGNIKDIKSKLGKRGLIAVAGGVTPEKVDTALANGANIIIAGRYIIGSSDVRRAAEDFLRYLPQDSDTMRLAL
DEDEKI

Sequences:

>Translated_406_residues
MSDIYEIGEALIGDGPELAHIDLIVGSKQGPVGTAFATNMASMSVGHTPLLSVIRPNLPTKPATLIVPKVTVQNLDDASK
IFGPAQTAVGRAVADAVEEEIIPKDIVEDIVLMVNVFIDPSAKDYRKIYQYNYGATKLAIKRAFDKYPSVDKVLAEKDRG
THPIMGFKAMKLWNPPYLQVALDLDNEDRMRSIIRDLPKRERILIEAGTPLVKKFGVEIISKIREERPGAFIIADLKTLD
VGRVEVKMAADETADAVAISGLGTNESIEKAIHECSKQGIYSILDMMNVSDIPSKLEELKLKPNIVLLHRNIDSETMRDN
DGEQQSEWGNIKDIKSKLGKRGLIAVAGGVTPEKVDTALANGANIIIAGRYIIGSSDVRRAAEDFLRYLPQDSDTMRLAL
DEDEKI
>Mature_405_residues
SDIYEIGEALIGDGPELAHIDLIVGSKQGPVGTAFATNMASMSVGHTPLLSVIRPNLPTKPATLIVPKVTVQNLDDASKI
FGPAQTAVGRAVADAVEEEIIPKDIVEDIVLMVNVFIDPSAKDYRKIYQYNYGATKLAIKRAFDKYPSVDKVLAEKDRGT
HPIMGFKAMKLWNPPYLQVALDLDNEDRMRSIIRDLPKRERILIEAGTPLVKKFGVEIISKIREERPGAFIIADLKTLDV
GRVEVKMAADETADAVAISGLGTNESIEKAIHECSKQGIYSILDMMNVSDIPSKLEELKLKPNIVLLHRNIDSETMRDND
GEQQSEWGNIKDIKSKLGKRGLIAVAGGVTPEKVDTALANGANIIIAGRYIIGSSDVRRAAEDFLRYLPQDSDTMRLALD
EDEKI

Specific function: Catalyzes the formation of ribulose-5-phosphate and formaldehyde from 3-hexulose-6-phosphate

COG id: COG0269

COG function: function code G; 3-hexulose-6-phosphate synthase and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HPS/KGPDC family. HPS subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FAEHP_METST (Q2NE86)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448510.1
- ProteinModelPortal:   Q2NE86
- STRING:   Q2NE86
- GeneID:   3854897
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1498
- NMPDR:   fig|339860.6.peg.1432
- eggNOG:   arNOG04867
- HOGENOM:   HBG541183
- OMA:   YNYGATK
- ProtClustDB:   PRK13307
- BioCyc:   MSTA339860:MSP_1498-MONOMER
- HAMAP:   MF_01268
- InterPro:   IPR013785
- InterPro:   IPR020868
- InterPro:   IPR014826
- InterPro:   IPR001754
- InterPro:   IPR020568
- InterPro:   IPR000056
- InterPro:   IPR011060
- Gene3D:   G3DSA:3.20.20.70
- Gene3D:   G3DSA:3.30.230.60
- PANTHER:   PTHR11749
- SMART:   SM00934
- TIGRFAMs:   TIGR03126

Pfam domain/function: PF08714 Fae; PF00215 OMPdecase; SSF54211 Ribosomal_S5_D2-typ_fold; SSF51366 RibP_bind_barrel

EC number: =4.1.2.43

Molecular weight: Translated: 44586; Mature: 44455

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: ACT_SITE 20-20 BINDING 22-22 BINDING 51-51 BINDING 69-69 BINDING 71-71 BINDING 86-86

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDIYEIGEALIGDGPELAHIDLIVGSKQGPVGTAFATNMASMSVGHTPLLSVIRPNLPT
CCHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCC
KPATLIVPKVTVQNLDDASKIFGPAQTAVGRAVADAVEEEIIPKDIVEDIVLMVNVFIDP
CCCEEEEECHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
SAKDYRKIYQYNYGATKLAIKRAFDKYPSVDKVLAEKDRGTHPIMGFKAMKLWNPPYLQV
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEHEECCCCEEEE
ALDLDNEDRMRSIIRDLPKRERILIEAGTPLVKKFGVEIISKIREERPGAFIIADLKTLD
EEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECEEEC
VGRVEVKMAADETADAVAISGLGTNESIEKAIHECSKQGIYSILDMMNVSDIPSKLEELK
CCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
LKPNIVLLHRNIDSETMRDNDGEQQSEWGNIKDIKSKLGKRGLIAVAGGVTPEKVDTALA
CCCCEEEEEECCCCHHHCCCCCCCHHHCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
NGANIIIAGRYIIGSSDVRRAAEDFLRYLPQDSDTMRLALDEDEKI
CCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC
>Mature Secondary Structure 
SDIYEIGEALIGDGPELAHIDLIVGSKQGPVGTAFATNMASMSVGHTPLLSVIRPNLPT
CHHHHHHHHHHCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHCCCCCHHHHHHCCCCCC
KPATLIVPKVTVQNLDDASKIFGPAQTAVGRAVADAVEEEIIPKDIVEDIVLMVNVFIDP
CCCEEEEECHHHCCCCHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
SAKDYRKIYQYNYGATKLAIKRAFDKYPSVDKVLAEKDRGTHPIMGFKAMKLWNPPYLQV
CHHHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCCCCEEHEECCCCEEEE
ALDLDNEDRMRSIIRDLPKRERILIEAGTPLVKKFGVEIISKIREERPGAFIIADLKTLD
EEECCCHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHCCCCEEEEEECEEEC
VGRVEVKMAADETADAVAISGLGTNESIEKAIHECSKQGIYSILDMMNVSDIPSKLEELK
CCCEEEEEECCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHC
LKPNIVLLHRNIDSETMRDNDGEQQSEWGNIKDIKSKLGKRGLIAVAGGVTPEKVDTALA
CCCCEEEEEECCCCHHHCCCCCCCHHHCCCHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
NGANIIIAGRYIIGSSDVRRAAEDFLRYLPQDSDTMRLALDEDEKI
CCCEEEEEEEEEECCHHHHHHHHHHHHHCCCCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA