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The map label for this gene is arsB [H]

Identifier: 84490124

GI number: 84490124

Start: 1503285

End: 1504232

Strand: Direct

Name: arsB [H]

Synonym: Msp_1336

Alternate gene names: 84490124

Gene position: 1503285-1504232 (Clockwise)

Preceding gene: 84490123

Following gene: 84490125

Centisome position: 85.06

GC content: 24.26

Gene sequence:

>948_bases
ATGAATATGATAGAAAAATTAGAGCCAATTTTAATTTTTGGAGCTATTATACTAGGATTACTATTTAAGGATATTTCCTT
ATTAAATAATATAAGCCCCTTACTTATAACTGTTTTTCTAGCATTAATGTTATTTGCACTGTTTTTAGATATTCCCCTCG
AGGATATTAGAAGTAGTTTTTCAAATAGAAAATTCACAATAATTAGTATTTTAATTAATTTTATATGGACACCACTTTTT
GGATATTTTCTAGGAAGCTTATTTTTATATGGACATGTTGATATTTTTATAGGATTTTTCATGTTAATATTAACTCCATG
TACTGATTGGTATTTGTTATTTACTAAAATATCCAAGGGAAATGTTCCACTTAGTTTATCTATACTACCAATTAACTTAC
TGTTACAGATAATATTACTACCAGTATATTTAGTGTTATTTTTCTCAAATTCTAATAATATTGTAATGTTGGATTTAGTA
GATGGGTTGTTGACATTTATTATTATCCCATTTATTGGATCAGAAGTTGTTAAATTTATTCTTAGAAATAAAAATAAGAC
TAAAGAAAAAATTACTGGATTTTTTTCAAGTTGTCAAATACTATTTTTATGTATTGCAATATTTGGATTGTTTAATACTG
AAGCAAGTAGTCTTTTTGAAAACTTAGATGTAATTGGTCTTATATTTATTCCATTAATGATATTTTTCATAGTTAATTTC
ATATTAGATTTTATTTTATCTAGACAACTGGATTTTAATTATGAAAATTATGTAAGTTTAACTCTTACAACATTAGCACG
TAATTCCCCACTTGCACTTGCTATTGCTATAAAATCCTTTCCAAACAATGAATTAATTGCAATAGCATTAGTAGTTGGAC
CATTAATTGAATTACCTGTTTTATATATTGTATCAAGAGTGTTGTTATATATACAAAAAAAATATTAG

Upstream 100 bases:

>100_bases
TACAGAAGCAAATTACCTTGAAAGAAGAGGATTCCTAAAAATATAATAAAATATAAAACAATCCTAATAATAGCTCTTAT
AATAATTAGAGGTTAATAAT

Downstream 100 bases:

>100_bases
GTAATAAAAATACAAAAGAATAATAAGAAGTAGAAGAGGGTTGTTACTTGAATAAACACTATATTGATGCAGATAAGCAA
ATGAGAAAATTAGAAGAAAC

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 315; Mature: 315

Protein sequence:

>315_residues
MNMIEKLEPILIFGAIILGLLFKDISLLNNISPLLITVFLALMLFALFLDIPLEDIRSSFSNRKFTIISILINFIWTPLF
GYFLGSLFLYGHVDIFIGFFMLILTPCTDWYLLFTKISKGNVPLSLSILPINLLLQIILLPVYLVLFFSNSNNIVMLDLV
DGLLTFIIIPFIGSEVVKFILRNKNKTKEKITGFFSSCQILFLCIAIFGLFNTEASSLFENLDVIGLIFIPLMIFFIVNF
ILDFILSRQLDFNYENYVSLTLTTLARNSPLALAIAIKSFPNNELIAIALVVGPLIELPVLYIVSRVLLYIQKKY

Sequences:

>Translated_315_residues
MNMIEKLEPILIFGAIILGLLFKDISLLNNISPLLITVFLALMLFALFLDIPLEDIRSSFSNRKFTIISILINFIWTPLF
GYFLGSLFLYGHVDIFIGFFMLILTPCTDWYLLFTKISKGNVPLSLSILPINLLLQIILLPVYLVLFFSNSNNIVMLDLV
DGLLTFIIIPFIGSEVVKFILRNKNKTKEKITGFFSSCQILFLCIAIFGLFNTEASSLFENLDVIGLIFIPLMIFFIVNF
ILDFILSRQLDFNYENYVSLTLTTLARNSPLALAIAIKSFPNNELIAIALVVGPLIELPVLYIVSRVLLYIQKKY
>Mature_315_residues
MNMIEKLEPILIFGAIILGLLFKDISLLNNISPLLITVFLALMLFALFLDIPLEDIRSSFSNRKFTIISILINFIWTPLF
GYFLGSLFLYGHVDIFIGFFMLILTPCTDWYLLFTKISKGNVPLSLSILPINLLLQIILLPVYLVLFFSNSNNIVMLDLV
DGLLTFIIIPFIGSEVVKFILRNKNKTKEKITGFFSSCQILFLCIAIFGLFNTEASSLFENLDVIGLIFIPLMIFFIVNF
ILDFILSRQLDFNYENYVSLTLTTLARNSPLALAIAIKSFPNNELIAIALVVGPLIELPVLYIVSRVLLYIQKKY

Specific function: Seems to confer resistance to arsenite by allowing cells to extrude this compound. Could be part of an arsenite extrusion pump [H]

COG id: COG0798

COG function: function code P; Arsenite efflux pump ACR3 and related permeases

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ACR3 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004706
- InterPro:   IPR002657 [H]

Pfam domain/function: PF01758 SBF [H]

EC number: NA

Molecular weight: Translated: 35810; Mature: 35810

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNMIEKLEPILIFGAIILGLLFKDISLLNNISPLLITVFLALMLFALFLDIPLEDIRSSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SNRKFTIISILINFIWTPLFGYFLGSLFLYGHVDIFIGFFMLILTPCTDWYLLFTKISKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCC
NVPLSLSILPINLLLQIILLPVYLVLFFSNSNNIVMLDLVDGLLTFIIIPFIGSEVVKFI
CCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
LRNKNKTKEKITGFFSSCQILFLCIAIFGLFNTEASSLFENLDVIGLIFIPLMIFFIVNF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDFILSRQLDFNYENYVSLTLTTLARNSPLALAIAIKSFPNNELIAIALVVGPLIELPV
HHHHHHHHCCCCCCHHHHHEEEHHHHCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHH
LYIVSRVLLYIQKKY
HHHHHHHHHHHHHCC
>Mature Secondary Structure
MNMIEKLEPILIFGAIILGLLFKDISLLNNISPLLITVFLALMLFALFLDIPLEDIRSSF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
SNRKFTIISILINFIWTPLFGYFLGSLFLYGHVDIFIGFFMLILTPCTDWYLLFTKISKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHEEECCC
NVPLSLSILPINLLLQIILLPVYLVLFFSNSNNIVMLDLVDGLLTFIIIPFIGSEVVKFI
CCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
LRNKNKTKEKITGFFSSCQILFLCIAIFGLFNTEASSLFENLDVIGLIFIPLMIFFIVNF
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILDFILSRQLDFNYENYVSLTLTTLARNSPLALAIAIKSFPNNELIAIALVVGPLIELPV
HHHHHHHHCCCCCCHHHHHEEEHHHHCCCCEEEEEEEECCCCCCCEEHHHHHHHHHHHHH
LYIVSRVLLYIQKKY
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7704261; 8969508; 9384377; 7489895; 9537360 [H]