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The map label for this gene is eif1a

Identifier: 84490123

GI number: 84490123

Start: 1502895

End: 1503230

Strand: Direct

Name: eif1a

Synonym: Msp_1335

Alternate gene names: 84490123

Gene position: 1502895-1503230 (Clockwise)

Preceding gene: 84490122

Following gene: 84490124

Centisome position: 85.03

GC content: 31.55

Gene sequence:

>336_bases
TTGAAGAAATCTAACAATAAAAATAATCATAAAAATAACCATAATAACAATCAAGGTGGAGAAAACATACGTGTAAGATC
ACCTAGACGTGGTGAAATTCCAGGAGTTGTTGAACAAATATTAGGACATGGAAAACTTAAAGTAAGATGTAATGATAAAC
AAATCAGATTATGTCGTATTCCTGGTAAAATGAAAAAACGTATATGGATTCGTGAAGGTGATGTTGTACTTGTAAAACCA
TGGGATTTCCAAAGTGATGAAAAAGCAGATGTTATTTGGAGATACACCCGTACAGAAGCAAATTACCTTGAAAGAAGAGG
ATTCCTAAAAATATAA

Upstream 100 bases:

>100_bases
AGTAATATAAAGTTAGTATTTCTAAGGAAGATACTAAAATAAGAAGATGAGATTTTAGGATAATTAATTCATAAAGGAAA
ATTATGGGAGGACATATATT

Downstream 100 bases:

>100_bases
TAAAATATAAAACAATCCTAATAATAGCTCTTATAATAATTAGAGGTTAATAATATGAATATGATAGAAAAATTAGAGCC
AATTTTAATTTTTGGAGCTA

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A

Number of amino acids: Translated: 111; Mature: 111

Protein sequence:

>111_residues
MKKSNNKNNHKNNHNNNQGGENIRVRSPRRGEIPGVVEQILGHGKLKVRCNDKQIRLCRIPGKMKKRIWIREGDVVLVKP
WDFQSDEKADVIWRYTRTEANYLERRGFLKI

Sequences:

>Translated_111_residues
MKKSNNKNNHKNNHNNNQGGENIRVRSPRRGEIPGVVEQILGHGKLKVRCNDKQIRLCRIPGKMKKRIWIREGDVVLVKP
WDFQSDEKADVIWRYTRTEANYLERRGFLKI
>Mature_111_residues
MKKSNNKNNHKNNHNNNQGGENIRVRSPRRGEIPGVVEQILGHGKLKVRCNDKQIRLCRIPGKMKKRIWIREGDVVLVKP
WDFQSDEKADVIWRYTRTEANYLERRGFLKI

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain

Homologues:

Organism=Homo sapiens, GI4503499, Length=79, Percent_Identity=43.0379746835443, Blast_Score=63, Evalue=4e-11,
Organism=Homo sapiens, GI33356163, Length=79, Percent_Identity=43.0379746835443, Blast_Score=63, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17540984, Length=79, Percent_Identity=43.0379746835443, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323916, Length=79, Percent_Identity=35.4430379746835, Blast_Score=60, Evalue=5e-11,
Organism=Drosophila melanogaster, GI45553405, Length=71, Percent_Identity=47.887323943662, Blast_Score=69, Evalue=8e-13,
Organism=Drosophila melanogaster, GI24647907, Length=71, Percent_Identity=47.887323943662, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF1A_METST (Q2NEP1)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448355.1
- ProteinModelPortal:   Q2NEP1
- SMR:   Q2NEP1
- STRING:   Q2NEP1
- GeneID:   3855658
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1335
- NMPDR:   fig|339860.6.peg.1281
- eggNOG:   arNOG11452
- HOGENOM:   HBG521228
- OMA:   IWIREGD
- ProtClustDB:   PRK04012
- BioCyc:   MSTA339860:MSP_1335-MONOMER
- HAMAP:   MF_00216
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR21668
- ProDom:   PD005579
- SMART:   SM00652
- TIGRFAMs:   TIGR00523

Pfam domain/function: PF01176 eIF-1a; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 13133; Mature: 13133

Theoretical pI: Translated: 11.10; Mature: 11.10

Prosite motif: PS01262 IF1A; PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKSNNKNNHKNNHNNNQGGENIRVRSPRRGEIPGVVEQILGHGKLKVRCNDKQIRLCRI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCEEEEEECCCEEEEEEC
PGKMKKRIWIREGDVVLVKPWDFQSDEKADVIWRYTRTEANYLERRGFLKI
CCCCCEEEEEECCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHCCCCCCC
>Mature Secondary Structure
MKKSNNKNNHKNNHNNNQGGENIRVRSPRRGEIPGVVEQILGHGKLKVRCNDKQIRLCRI
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHHHHHCCCEEEEEECCCEEEEEEC
PGKMKKRIWIREGDVVLVKPWDFQSDEKADVIWRYTRTEANYLERRGFLKI
CCCCCEEEEEECCCEEEEECCCCCCCCCCEEEEEEECCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA