Click here to switch to the map view.

The map label for this gene is glmM

Identifier: 84490088

GI number: 84490088

Start: 1463928

End: 1465286

Strand: Direct

Name: glmM

Synonym: Msp_1300

Alternate gene names: 84490088

Gene position: 1463928-1465286 (Clockwise)

Preceding gene: 84490087

Following gene: 84490089

Centisome position: 82.83

GC content: 32.6

Gene sequence:

>1359_bases
ATGAAAAGCATACCAAAACTATTTGGAACCTCAGGAATTAGAGGAAAATATCAGGAAGAAATTACATTAGAACTAGCATT
AGATGTTGCTAGAGCTTTAGCTAAATATATTGGTGGAAAAAATAAGAAAGTTGTAATAGGAAGAGATACAAGAACTTCTG
GTAAAATCATTGAGAATGTAATGTCTGCAGGATTACAACAATCAGGATGTGATGTATTACTTCTTGGTATGGTTCCAACA
CCAGTTGTAGGATATGCAACCTTAAAAAAAGAAGCTGATGCAGGAATTATGATAACAGCTTCACATAATCCTTCACAATA
CAATGGAATTAAACTATGGAACAGTGATGGATTAGCATATAAACAAGACCAAGAAAGAACAATTGAAAAATTAGTCTATG
AAAAAGATTTTAATATTGTTAAATGGAATGAAATTGGAAAAGAATACGATATTAGTTCATTCAAAGATAAATATATCGAT
GATATCGTTGCTAAATCTGGAATTAATCCTTTAAAACCATTGAAAGTTGTTGTTGACTGTGCATGTGGTGCAGGTTCTTA
TTTATCCCCAGAAGCTTTAAGAAGAGCTGGTATGAATGTGATTACACTTAATGCACAACCTGATGGATCGTTCCCAGGAC
GTAGACCAGAACCAAATGAGGCTAACTTAGGAGAATTAATGAAAACAGTGAAAGCATTAAATGCTGATGTGGGTTTAGCC
CATGATGGGGATGCTGATAGAATGATTGCTGTGGATGAAAATGGAAATTTATCTGATTTTGATAAATTACTTACTATTAT
GGCAAAAGAGTTTGGTGGTACTGTTGTAACCACAGTTGATGCTTCAGCTTGTTTAGATATTCAGATGCAAAAAATCGGTG
GAAATGTTCTTAGAACACCTGTTGGTGATGTTCACGTAGCTGAATCTATAAATAAAAATAAAGGAACATTTGGTGGAGAA
CCTTCTGGTACATGGTTACATCCTGATTTCTGTATGTGTCCAGATGGACTTCTTTCTGGTTTAAGAATAGTTAGAACAAT
ACAGAAAAATGGTAAGTTATCAAAGCAATTAGATGCTATTGAAAATTATCCTACTATAAGACAAAAAGTTACTTGTGAAA
ATAGTAAAAAGAAAACTGTTATGAGTATTGTTGAAGAGAAATTTGAAGAGGAATTTGATGATGTTAAAGAAATTCTTACA
ATTGATGGTGTTCGTATTTCCTTTGAAGATGATAGTTGGGTTTTAATAAGACCTTCTGGAACTGAACCATACATTAGAAT
TACTGCTGAAGGTAAAACTCAGGAACATCTTAATAGTATTGAAAAAATATCCAATGAATTCCTAAACAACATCATATAA

Upstream 100 bases:

>100_bases
ATGTATATGTAAATAAGAAAATATTAAACTATGAAATTAACAACTATTCTTTTAAAGATTAAATGATAAATATGTTAACA
GATATAAGGAGTTATAATAT

Downstream 100 bases:

>100_bases
TTCACCTCCTTTTTTCTCTATTTTTAAAAAAAAACCATATATACAACTTATTTTATATCATTGATTAAAAATAGTATTCA
TTAAACTATATTAAAAATGT

Product: phosphomannomutase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKSIPKLFGTSGIRGKYQEEITLELALDVARALAKYIGGKNKKVVIGRDTRTSGKIIENVMSAGLQQSGCDVLLLGMVPT
PVVGYATLKKEADAGIMITASHNPSQYNGIKLWNSDGLAYKQDQERTIEKLVYEKDFNIVKWNEIGKEYDISSFKDKYID
DIVAKSGINPLKPLKVVVDCACGAGSYLSPEALRRAGMNVITLNAQPDGSFPGRRPEPNEANLGELMKTVKALNADVGLA
HDGDADRMIAVDENGNLSDFDKLLTIMAKEFGGTVVTTVDASACLDIQMQKIGGNVLRTPVGDVHVAESINKNKGTFGGE
PSGTWLHPDFCMCPDGLLSGLRIVRTIQKNGKLSKQLDAIENYPTIRQKVTCENSKKKTVMSIVEEKFEEEFDDVKEILT
IDGVRISFEDDSWVLIRPSGTEPYIRITAEGKTQEHLNSIEKISNEFLNNII

Sequences:

>Translated_452_residues
MKSIPKLFGTSGIRGKYQEEITLELALDVARALAKYIGGKNKKVVIGRDTRTSGKIIENVMSAGLQQSGCDVLLLGMVPT
PVVGYATLKKEADAGIMITASHNPSQYNGIKLWNSDGLAYKQDQERTIEKLVYEKDFNIVKWNEIGKEYDISSFKDKYID
DIVAKSGINPLKPLKVVVDCACGAGSYLSPEALRRAGMNVITLNAQPDGSFPGRRPEPNEANLGELMKTVKALNADVGLA
HDGDADRMIAVDENGNLSDFDKLLTIMAKEFGGTVVTTVDASACLDIQMQKIGGNVLRTPVGDVHVAESINKNKGTFGGE
PSGTWLHPDFCMCPDGLLSGLRIVRTIQKNGKLSKQLDAIENYPTIRQKVTCENSKKKTVMSIVEEKFEEEFDDVKEILT
IDGVRISFEDDSWVLIRPSGTEPYIRITAEGKTQEHLNSIEKISNEFLNNII
>Mature_452_residues
MKSIPKLFGTSGIRGKYQEEITLELALDVARALAKYIGGKNKKVVIGRDTRTSGKIIENVMSAGLQQSGCDVLLLGMVPT
PVVGYATLKKEADAGIMITASHNPSQYNGIKLWNSDGLAYKQDQERTIEKLVYEKDFNIVKWNEIGKEYDISSFKDKYID
DIVAKSGINPLKPLKVVVDCACGAGSYLSPEALRRAGMNVITLNAQPDGSFPGRRPEPNEANLGELMKTVKALNADVGLA
HDGDADRMIAVDENGNLSDFDKLLTIMAKEFGGTVVTTVDASACLDIQMQKIGGNVLRTPVGDVHVAESINKNKGTFGGE
PSGTWLHPDFCMCPDGLLSGLRIVRTIQKNGKLSKQLDAIENYPTIRQKVTCENSKKKTVMSIVEEKFEEEFDDVKEILT
IDGVRISFEDDSWVLIRPSGTEPYIRITAEGKTQEHLNSIEKISNEFLNNII

Specific function: Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family

Homologues:

Organism=Homo sapiens, GI31377548, Length=294, Percent_Identity=28.5714285714286, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1789566, Length=446, Percent_Identity=32.5112107623318, Blast_Score=191, Evalue=6e-50,
Organism=Escherichia coli, GI1788361, Length=440, Percent_Identity=27.7272727272727, Blast_Score=159, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI71993878, Length=293, Percent_Identity=27.6450511945392, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71993870, Length=280, Percent_Identity=28.2142857142857, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI17864244, Length=495, Percent_Identity=24.6464646464646, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GLMM_METST (Q2NES6)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448320.1
- ProteinModelPortal:   Q2NES6
- SMR:   Q2NES6
- STRING:   Q2NES6
- GeneID:   3856133
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1300
- NMPDR:   fig|339860.6.peg.1247
- eggNOG:   arNOG04251
- HOGENOM:   HBG644964
- OMA:   WIFPKIS
- PhylomeDB:   Q2NES6
- ProtClustDB:   CLSK798213
- BioCyc:   MSTA339860:MSP_1300-MONOMER
- HAMAP:   MF_01554_A
- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841
- Gene3D:   G3DSA:3.40.120.10
- PRINTS:   PR00509

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV; SSF53738 A-D-PHexomutase_a/b/a-I/II/III

EC number: =5.4.2.10

Molecular weight: Translated: 49605; Mature: 49605

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS00710 PGM_PMM

Important sites: ACT_SITE 101-101

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSIPKLFGTSGIRGKYQEEITLELALDVARALAKYIGGKNKKVVIGRDTRTSGKIIENV
CCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
MSAGLQQSGCDVLLLGMVPTPVVGYATLKKEADAGIMITASHNPSQYNGIKLWNSDGLAY
HHCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCCC
KQDQERTIEKLVYEKDFNIVKWNEIGKEYDISSFKDKYIDDIVAKSGINPLKPLKVVVDC
CCHHHHHHHHHHHHCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHEEC
ACGAGSYLSPEALRRAGMNVITLNAQPDGSFPGRRPEPNEANLGELMKTVKALNADVGLA
CCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
HDGDADRMIAVDENGNLSDFDKLLTIMAKEFGGTVVTTVDASACLDIQMQKIGGNVLRTP
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHEEEHHHCCCEEECC
VGDVHVAESINKNKGTFGGEPSGTWLHPDFCMCPDGLLSGLRIVRTIQKNGKLSKQLDAI
CCCCHHHHHCCCCCCCCCCCCCCCEECCCHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ENYPTIRQKVTCENSKKKTVMSIVEEKFEEEFDDVKEILTIDGVRISFEDDSWVLIRPSG
HCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCC
TEPYIRITAEGKTQEHLNSIEKISNEFLNNII
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKSIPKLFGTSGIRGKYQEEITLELALDVARALAKYIGGKNKKVVIGRDTRTSGKIIENV
CCCCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
MSAGLQQSGCDVLLLGMVPTPVVGYATLKKEADAGIMITASHNPSQYNGIKLWNSDGLAY
HHCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCCEEEECCCCCCC
KQDQERTIEKLVYEKDFNIVKWNEIGKEYDISSFKDKYIDDIVAKSGINPLKPLKVVVDC
CCHHHHHHHHHHHHCCCCEEEHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHEEC
ACGAGSYLSPEALRRAGMNVITLNAQPDGSFPGRRPEPNEANLGELMKTVKALNADVGLA
CCCCCCCCCHHHHHHCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCC
HDGDADRMIAVDENGNLSDFDKLLTIMAKEFGGTVVTTVDASACLDIQMQKIGGNVLRTP
CCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCCEEEEEECCCHHHHEEEHHHCCCEEECC
VGDVHVAESINKNKGTFGGEPSGTWLHPDFCMCPDGLLSGLRIVRTIQKNGKLSKQLDAI
CCCCHHHHHCCCCCCCCCCCCCCCEECCCHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
ENYPTIRQKVTCENSKKKTVMSIVEEKFEEEFDDVKEILTIDGVRISFEDDSWVLIRPSG
HCCCCHHHEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEEECCC
TEPYIRITAEGKTQEHLNSIEKISNEFLNNII
CCCEEEEEECCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA