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The map label for this gene is pol [H]

Identifier: 84490069

GI number: 84490069

Start: 1444599

End: 1445249

Strand: Direct

Name: pol [H]

Synonym: Msp_1281

Alternate gene names: 84490069

Gene position: 1444599-1445249 (Clockwise)

Preceding gene: 84490068

Following gene: 84490074

Centisome position: 81.74

GC content: 31.34

Gene sequence:

>651_bases
ATGAGCATTCCAAAAAAAATTGAAAAACAGGTTACGGAGCTACTTAGCTCCATAAACCAAAATTTACCCCAAGACATGGA
GCTTGAGTTAGAAGGCTATTATGACAGAGGATTCTTTGTAACCAAAAAAAGATATGCTGTCATATGTGATGGTGTTATTA
CTGTTAAAGGTTTAGAACTTGTTCGTCGTGATTGGGCAGCAGTAGCTAAAAATACCCAACATGAAGTATTAGAAGCTATT
CTTAAGGATGCTTCACCAAATAAAGCAAAAAAAATTGTGAAAAATGTTATTAAAAGATTAAATAATGGTGAAGTTGAATT
AGAAGATTTAGTTATCCATACTAAATTAACTAAAAAACCTGAAAACTATAAGCAAATTGCACCACATGTGATTGCTGCAG
AAAAACTAGAGTTACATGGCCAAACAGTTACTAGTGGTTCTATTATTCGTTACATTATTACAAAAGGAAAAGAACCAATT
AGTAGACGTGCAGAACCAATAGAATATATTGGAAATAAAACATATGATCCTGAGTATTACATTCAAAATCAAGTATTACC
AGCTACTTTAAGAATACTAGAAGCTATAGGATACACTGAAGAACAGATTATGAACAATGAAATACAAACAAGTTTAGATA
GTTTCTTCTAA

Upstream 100 bases:

>100_bases
ACATTATTACAAAAGGAGCTATTGTTGAAACAGAAATTGGTAAAGCAAAAATAACTTCCAGACCAGGTCAAAAAGGAATA
GTTAATGGTGTATTAATCGA

Downstream 100 bases:

>100_bases
ATAATAAATCACCGCCTAAAATAAATAATATCTTTTTTTCTTTAAAATATAACTTAATTTCTAGTAATTTTTACTTAGAA
TCATGAAAATTAAAACTACT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MSIPKKIEKQVTELLSSINQNLPQDMELELEGYYDRGFFVTKKRYAVICDGVITVKGLELVRRDWAAVAKNTQHEVLEAI
LKDASPNKAKKIVKNVIKRLNNGEVELEDLVIHTKLTKKPENYKQIAPHVIAAEKLELHGQTVTSGSIIRYIITKGKEPI
SRRAEPIEYIGNKTYDPEYYIQNQVLPATLRILEAIGYTEEQIMNNEIQTSLDSFF

Sequences:

>Translated_216_residues
MSIPKKIEKQVTELLSSINQNLPQDMELELEGYYDRGFFVTKKRYAVICDGVITVKGLELVRRDWAAVAKNTQHEVLEAI
LKDASPNKAKKIVKNVIKRLNNGEVELEDLVIHTKLTKKPENYKQIAPHVIAAEKLELHGQTVTSGSIIRYIITKGKEPI
SRRAEPIEYIGNKTYDPEYYIQNQVLPATLRILEAIGYTEEQIMNNEIQTSLDSFF
>Mature_215_residues
SIPKKIEKQVTELLSSINQNLPQDMELELEGYYDRGFFVTKKRYAVICDGVITVKGLELVRRDWAAVAKNTQHEVLEAIL
KDASPNKAKKIVKNVIKRLNNGEVELEDLVIHTKLTKKPENYKQIAPHVIAAEKLELHGQTVTSGSIIRYIITKGKEPIS
RRAEPIEYIGNKTYDPEYYIQNQVLPATLRILEAIGYTEEQIMNNEIQTSLDSFF

Specific function: Thought To Be Involved In DNA Repair And/Or Mutagenesis. [C]

COG id: COG0417

COG function: function code L; DNA polymerase elongation subunit (family B)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-B family [H]

Homologues:

Organism=Homo sapiens, GI106507301, Length=195, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=8e-15,
Organism=Homo sapiens, GI156616275, Length=192, Percent_Identity=27.6041666666667, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI32565317, Length=159, Percent_Identity=29.559748427673, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6324227, Length=165, Percent_Identity=27.2727272727273, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006172
- InterPro:   IPR017964
- InterPro:   IPR006133
- InterPro:   IPR006134
- InterPro:   IPR004578
- InterPro:   IPR023211
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00136 DNA_pol_B; PF03104 DNA_pol_B_exo [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 24686; Mature: 24555

Theoretical pI: Translated: 7.65; Mature: 7.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIPKKIEKQVTELLSSINQNLPQDMELELEGYYDRGFFVTKKRYAVICDGVITVKGLEL
CCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECEECCCEEEECCCEEEEECCCHHHHHHHH
VRRDWAAVAKNTQHEVLEAILKDASPNKAKKIVKNVIKRLNNGEVELEDLVIHTKLTKKP
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEHHHEEEEHHHCCCC
ENYKQIAPHVIAAEKLELHGQTVTSGSIIRYIITKGKEPISRRAEPIEYIGNKTYDPEYY
CCHHHHCCHHHHHHHHHHCCCEECCCHHHHHHHHCCCCCHHHCCCHHHHHCCCCCCCCHH
IQNQVLPATLRILEAIGYTEEQIMNNEIQTSLDSFF
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SIPKKIEKQVTELLSSINQNLPQDMELELEGYYDRGFFVTKKRYAVICDGVITVKGLEL
CCHHHHHHHHHHHHHHHHHCCCCCCEEEEECEECCCEEEECCCEEEEECCCHHHHHHHH
VRRDWAAVAKNTQHEVLEAILKDASPNKAKKIVKNVIKRLNNGEVELEDLVIHTKLTKKP
HHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEHHHEEEEHHHCCCC
ENYKQIAPHVIAAEKLELHGQTVTSGSIIRYIITKGKEPISRRAEPIEYIGNKTYDPEYY
CCHHHHCCHHHHHHHHHHCCCEECCCHHHHHHHHCCCCCHHHCCCHHHHHCCCCCCCCHH
IQNQVLPATLRILEAIGYTEEQIMNNEIQTSLDSFF
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7929013 [H]