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The map label for this gene is 84490038

Identifier: 84490038

GI number: 84490038

Start: 1418133

End: 1418801

Strand: Direct

Name: 84490038

Synonym: Msp_1250

Alternate gene names: NA

Gene position: 1418133-1418801 (Clockwise)

Preceding gene: 84490037

Following gene: 84490039

Centisome position: 80.24

GC content: 26.31

Gene sequence:

>669_bases
ATGATATTTGTAGAAAATAAAGAAATAGTACTACCAGGTAGTTTATTAACAGACAATAATTATAAACTAGGTAGAGGTAC
TTATAAAGAAAATGGAAAGATATATTCCAGTATAACTGGATTAGTATACTTTGAAAGTGAACAAATAAAAGTAATTCCAC
TAAAAGATACATACAGTCCAAATTATGGTGATTTAGTTATTGGACGAGTAACTGGTTCATCATATTCTTCATGGTCTATT
GATATTAACAGCACATATCATGGTTTTCTACCAACAACAGAATTATATGATAAAAATGAGCCCAATATTAACAACATAAT
CAATATTAAAGATATGTTACTTCTTAGAGTAGCCAATGTTGATGAAATAAATAGAGTGAAGTTAACTCTAAGATCTAGAG
GTCTTGGTAAATTCAATCAAGGAACAATTATAAAAGTTAAACAACCAACAATACATTTTTTAAGTGAAGAAAATGCATTT
TTAACAACTATGATACAAGAATATACATATACTGATGTAATTATTGGAAAAAATGGACTTATATGGATAAATGGATTGAA
AGAAAATATTGAACGTATCATAGAAATAATAGAGCTTATTGAAAAAGAAGAACCACTAAAACATAACCTTATCAAACATA
TTCAAAGTATGATATTAAATCCAAAATAG

Upstream 100 bases:

>100_bases
AAATCCCTGGAGGACTACAAGATGAATTTTACACAGCACTAAGTGGTCTAACACATGGAGAGGTTGAAACCAAATTAATT
AAATAGATTGAAGTGTATCT

Downstream 100 bases:

>100_bases
AGGGATATAGTGACTAATGAATTTATAAGAAAAGATGGAAGAGCATATAATACTCTTAGAAACATGAAAATGGAAGTAGG
AGTTCTTAACAATGCTGATG

Product: exosome complex RNA-binding protein Rrp4

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MIFVENKEIVLPGSLLTDNNYKLGRGTYKENGKIYSSITGLVYFESEQIKVIPLKDTYSPNYGDLVIGRVTGSSYSSWSI
DINSTYHGFLPTTELYDKNEPNINNIINIKDMLLLRVANVDEINRVKLTLRSRGLGKFNQGTIIKVKQPTIHFLSEENAF
LTTMIQEYTYTDVIIGKNGLIWINGLKENIERIIEIIELIEKEEPLKHNLIKHIQSMILNPK

Sequences:

>Translated_222_residues
MIFVENKEIVLPGSLLTDNNYKLGRGTYKENGKIYSSITGLVYFESEQIKVIPLKDTYSPNYGDLVIGRVTGSSYSSWSI
DINSTYHGFLPTTELYDKNEPNINNIINIKDMLLLRVANVDEINRVKLTLRSRGLGKFNQGTIIKVKQPTIHFLSEENAF
LTTMIQEYTYTDVIIGKNGLIWINGLKENIERIIEIIELIEKEEPLKHNLIKHIQSMILNPK
>Mature_222_residues
MIFVENKEIVLPGSLLTDNNYKLGRGTYKENGKIYSSITGLVYFESEQIKVIPLKDTYSPNYGDLVIGRVTGSSYSSWSI
DINSTYHGFLPTTELYDKNEPNINNIINIKDMLLLRVANVDEINRVKLTLRSRGLGKFNQGTIIKVKQPTIHFLSEENAF
LTTMIQEYTYTDVIIGKNGLIWINGLKENIERIIEIIELIEKEEPLKHNLIKHIQSMILNPK

Specific function: Probably involved in degradation of a variety of RNA species; could act a RNA-binding component of the exosome (Potential) [H]

COG id: COG1097

COG function: function code J; RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI19923403, Length=202, Percent_Identity=28.7128712871287, Blast_Score=70, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6321860, Length=189, Percent_Identity=29.6296296296296, Blast_Score=72, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24762324, Length=199, Percent_Identity=28.643216080402, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004087
- InterPro:   IPR004088
- InterPro:   IPR018111
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967 [H]

Pfam domain/function: PF00013 KH_1 [H]

EC number: NA

Molecular weight: Translated: 25422; Mature: 25422

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50126 S1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFVENKEIVLPGSLLTDNNYKLGRGTYKENGKIYSSITGLVYFESEQIKVIPLKDTYSP
CEEECCCCEEECCCEEECCCEEECCCEECCCCEEEEEEEEEEEEECCCEEEEEECCCCCC
NYGDLVIGRVTGSSYSSWSIDINSTYHGFLPTTELYDKNEPNINNIINIKDMLLLRVANV
CCCCEEEEEEECCCCCEEEEEECCEECCCCCCHHHCCCCCCCCCCEEEHHHEEEEEECCC
DEINRVKLTLRSRGLGKFNQGTIIKVKQPTIHFLSEENAFLTTMIQEYTYTDVIIGKNGL
CCCEEEEEEEECCCCCCCCCCCEEEEECCEEEEECCCCCCEEHHHHHCCEEEEEECCCCE
IWINGLKENIERIIEIIELIEKEEPLKHNLIKHIQSMILNPK
EEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MIFVENKEIVLPGSLLTDNNYKLGRGTYKENGKIYSSITGLVYFESEQIKVIPLKDTYSP
CEEECCCCEEECCCEEECCCEEECCCEECCCCEEEEEEEEEEEEECCCEEEEEECCCCCC
NYGDLVIGRVTGSSYSSWSIDINSTYHGFLPTTELYDKNEPNINNIINIKDMLLLRVANV
CCCCEEEEEEECCCCCEEEEEECCEECCCCCCHHHCCCCCCCCCCEEEHHHEEEEEECCC
DEINRVKLTLRSRGLGKFNQGTIIKVKQPTIHFLSEENAFLTTMIQEYTYTDVIIGKNGL
CCCEEEEEEEECCCCCCCCCCCEEEEECCEEEEECCCCCCEEHHHHHCCEEEEEECCCCE
IWINGLKENIERIIEIIELIEKEEPLKHNLIKHIQSMILNPK
EEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA