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The map label for this gene is trpB

Identifier: 84489868

GI number: 84489868

Start: 1213857

End: 1215038

Strand: Direct

Name: trpB

Synonym: Msp_1074

Alternate gene names: 84489868

Gene position: 1213857-1215038 (Clockwise)

Preceding gene: 84489867

Following gene: 84489869

Centisome position: 68.68

GC content: 32.83

Gene sequence:

>1182_bases
ATGAAATATGAAGGAAAATTTGGAAAATATGGTGGTATCTTTGTACCAGAATTATTAATACCTGCAATTGAAGAATTAGA
AGAAGCATTCTACAAATTCAAAGATGATGAAGAATTTATGAATGAATTACATTTTTATCTTAAAGAATTTGCTTCTAGAC
CTACAGGCCTATATTATGCAGAAAATCTTTCAAATGAATTGGGATGTAAAATATATCTTAAAAGAGAAGATTTACTCCAC
ACTGGTGCTCATAAAATAAACAATGCTATTGGACAAGGATTACTAGCAAAGTACATGGGTAAAACCGAATTAATAGCAGA
AACTGGTGCTGGACAACATGGAATTGCAACTGCAGTAATTGGAGCTAAATTAGGATTGAAAGTAAAAATATTCATGGGAT
CTAAGGATGTTGAACGTCAAAAACTAAATGTATTCCGTATGGAATTATCAGGAGCCGAAGTAATTCCTGTTGATATGGGA
TCTAAAACCTTAAAAGATTCAATTAATGAAGCTTTCAGATACTGGATTTCCAACCTTGATACTAGTCATTATCTGATTGG
AACAACAATGGGACCACATCCATATCCTTCAATGGTGAAATTTTTCCAAAGTGTTATAGGAAAAGAAGCACGTGAACAAA
TACTTGAAAAAGAAAATAAACTTCCAGATACTGTTATAGCATGTGTTGGTGGAGGAAGTAATTCCATAGGTATTTTTAGT
GGATTTGTTGATGATGAAGATGTGGATCTTATTGGTGTTGAAGCAGCAGGTGATGGAATAGATACCAATGAACATGGAGC
TACTTTAACTAAGGGAACTGAAGGTATACTTCATGGATCATTATCTATTGTATTACAAGATGAAGATGGACAAATTAATG
ATACAAGTAGTGTTTCTGCAGGTTTAGACTATCCTGGAGTTGGACCAGAACATGCTTATTTACAAAGTAGTGGTAGAGCA
AAATATGTTCCTATTACAGATAAAGAAGCTTTAAATGCCTTTAGATTATTATGTGAAACTGAAGGAATTATACCTGCATT
AGAAAGTTCACATGCAGTAGCATATGCTGTTAAATATGCAAAACAAGAAGAAAATAAAGGAAAAACTATCATTGTAAACT
TATCAGGTCGTGGAGATAAGGATATGTTTACTGTAGCAAAAGAATTAGGGGTATCAATATGA

Upstream 100 bases:

>100_bases
AGAATAGATCTAAATAGTGGAGTAGAAGAAAAGCCTGGAAAGAAAAATATAAAAAAAATTAAAGAGATTATTAAATTAAT
TGAAGAATGAATGTGATATG

Downstream 100 bases:

>100_bases
GTATGAAAACATATACAGAAGTTTTTAAAAAATCTAAGGAAAATAATGAAGGAATATTCATACCATTTCTAGTGGCAGGA
GATCCTGACTATGACACATC

Product: tryptophan synthase subunit beta

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MKYEGKFGKYGGIFVPELLIPAIEELEEAFYKFKDDEEFMNELHFYLKEFASRPTGLYYAENLSNELGCKIYLKREDLLH
TGAHKINNAIGQGLLAKYMGKTELIAETGAGQHGIATAVIGAKLGLKVKIFMGSKDVERQKLNVFRMELSGAEVIPVDMG
SKTLKDSINEAFRYWISNLDTSHYLIGTTMGPHPYPSMVKFFQSVIGKEAREQILEKENKLPDTVIACVGGGSNSIGIFS
GFVDDEDVDLIGVEAAGDGIDTNEHGATLTKGTEGILHGSLSIVLQDEDGQINDTSSVSAGLDYPGVGPEHAYLQSSGRA
KYVPITDKEALNAFRLLCETEGIIPALESSHAVAYAVKYAKQEENKGKTIIVNLSGRGDKDMFTVAKELGVSI

Sequences:

>Translated_393_residues
MKYEGKFGKYGGIFVPELLIPAIEELEEAFYKFKDDEEFMNELHFYLKEFASRPTGLYYAENLSNELGCKIYLKREDLLH
TGAHKINNAIGQGLLAKYMGKTELIAETGAGQHGIATAVIGAKLGLKVKIFMGSKDVERQKLNVFRMELSGAEVIPVDMG
SKTLKDSINEAFRYWISNLDTSHYLIGTTMGPHPYPSMVKFFQSVIGKEAREQILEKENKLPDTVIACVGGGSNSIGIFS
GFVDDEDVDLIGVEAAGDGIDTNEHGATLTKGTEGILHGSLSIVLQDEDGQINDTSSVSAGLDYPGVGPEHAYLQSSGRA
KYVPITDKEALNAFRLLCETEGIIPALESSHAVAYAVKYAKQEENKGKTIIVNLSGRGDKDMFTVAKELGVSI
>Mature_393_residues
MKYEGKFGKYGGIFVPELLIPAIEELEEAFYKFKDDEEFMNELHFYLKEFASRPTGLYYAENLSNELGCKIYLKREDLLH
TGAHKINNAIGQGLLAKYMGKTELIAETGAGQHGIATAVIGAKLGLKVKIFMGSKDVERQKLNVFRMELSGAEVIPVDMG
SKTLKDSINEAFRYWISNLDTSHYLIGTTMGPHPYPSMVKFFQSVIGKEAREQILEKENKLPDTVIACVGGGSNSIGIFS
GFVDDEDVDLIGVEAAGDGIDTNEHGATLTKGTEGILHGSLSIVLQDEDGQINDTSSVSAGLDYPGVGPEHAYLQSSGRA
KYVPITDKEALNAFRLLCETEGIIPALESSHAVAYAVKYAKQEENKGKTIIVNLSGRGDKDMFTVAKELGVSI

Specific function: The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine [H]

COG id: COG0133

COG function: function code E; Tryptophan synthase beta chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpB family [H]

Homologues:

Organism=Escherichia coli, GI1787515, Length=379, Percent_Identity=58.8390501319261, Blast_Score=474, Evalue=1e-135,
Organism=Saccharomyces cerevisiae, GI6321412, Length=390, Percent_Identity=55.3846153846154, Blast_Score=434, Evalue=1e-122,

Paralogues:

None

Copy number: 360 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR006653
- InterPro:   IPR006654
- InterPro:   IPR023026 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.1.20 [H]

Molecular weight: Translated: 42851; Mature: 42851

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00168 TRP_SYNTHASE_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYEGKFGKYGGIFVPELLIPAIEELEEAFYKFKDDEEFMNELHFYLKEFASRPTGLYYA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEH
ENLSNELGCKIYLKREDLLHTGAHKINNAIGQGLLAKYMGKTELIAETGAGQHGIATAVI
HCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHH
GAKLGLKVKIFMGSKDVERQKLNVFRMELSGAEVIPVDMGSKTLKDSINEAFRYWISNLD
HHCCCEEEEEEECCCCHHHHHHHEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
TSHYLIGTTMGPHPYPSMVKFFQSVIGKEAREQILEKENKLPDTVIACVGGGSNSIGIFS
CCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEE
GFVDDEDVDLIGVEAAGDGIDTNEHGATLTKGTEGILHGSLSIVLQDEDGQINDTSSVSA
CCCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCCEEECEEEEEEECCCCCCCCCCCCCC
GLDYPGVGPEHAYLQSSGRAKYVPITDKEALNAFRLLCETEGIIPALESSHAVAYAVKYA
CCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KQEENKGKTIIVNLSGRGDKDMFTVAKELGVSI
HHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure
MKYEGKFGKYGGIFVPELLIPAIEELEEAFYKFKDDEEFMNELHFYLKEFASRPTGLYYA
CCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCEEEH
ENLSNELGCKIYLKREDLLHTGAHKINNAIGQGLLAKYMGKTELIAETGAGQHGIATAVI
HCCCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEECCCCCCCHHHHHH
GAKLGLKVKIFMGSKDVERQKLNVFRMELSGAEVIPVDMGSKTLKDSINEAFRYWISNLD
HHCCCEEEEEEECCCCHHHHHHHEEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHCCC
TSHYLIGTTMGPHPYPSMVKFFQSVIGKEAREQILEKENKLPDTVIACVGGGSNSIGIFS
CCEEEEEECCCCCCCHHHHHHHHHHHCHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEE
GFVDDEDVDLIGVEAAGDGIDTNEHGATLTKGTEGILHGSLSIVLQDEDGQINDTSSVSA
CCCCCCCCCEEEEEECCCCCCCCCCCCEEECCCCCEEECEEEEEEECCCCCCCCCCCCCC
GLDYPGVGPEHAYLQSSGRAKYVPITDKEALNAFRLLCETEGIIPALESSHAVAYAVKYA
CCCCCCCCCCHHHHHCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
KQEENKGKTIIVNLSGRGDKDMFTVAKELGVSI
HHHCCCCCEEEEEECCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9371463 [H]