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The map label for this gene is fixC [C]

Identifier: 84489857

GI number: 84489857

Start: 1203693

End: 1204874

Strand: Direct

Name: fixC [C]

Synonym: Msp_1062

Alternate gene names: 84489857

Gene position: 1203693-1204874 (Clockwise)

Preceding gene: 84489856

Following gene: 84489858

Centisome position: 68.11

GC content: 32.23

Gene sequence:

>1182_bases
ATGATTGAAACTGATATTTTAGTAGTTGGAGCAGGACCTTCAGGATCACTAGCAGCAAAAGAAGCAGCATTACATGGTGC
TGATGTTATATTAATAGATAGAAAATCTGAAATAGGATCACCAAAACGTTGTGCTGAAGGAGTTTCCAAGGATGGATTAG
CACAATTAGGTATTAAACCTGATCCTAGATGGATTGCACGGGATTTATATGGGGTAAGATTAGTATCACCAAATAATACA
AGTGTATGGATGGATAATAATACTATTAAAATACCTGAAGCAGGATATATACTTGAAAGAAAAGTATTTGATAAACATAT
GGCAATGGATGCTGCACGTGCTGGTGCTAAAATAATGATAAAAACAAATGCTACTTCCCTAAAAAGAGTAGATGATGGAA
TTATTGTTAGTACAAACCATATGGGTAAAGACATAGATATACATGCTAAAATTGTAATTGCCGCTGATGGACCTGAATCT
CGTATAGGTAGATGGGCTGGACTTGAATGTAACACAGAATTTAAATATATGGAATCCTGTATACAATTTGAAATGGCTGG
AGTTAATATGGAAAACAATAGGGATATTGCATTGTTCTTTGGAAGTGTTGCTCCAGGAGGATATGTATGGATATTCCCTA
AAGGTGATGACATAGCAAATGTTGGTATTGGAGTTCTTAAAAATAAAACCAATAAAACAGCATATGAACATTTAATGGAA
TTTATAAAAACTTGTCCTGAAACTAAAGATGCTCAACCTGTTGAAATAAATGTTGGTGGAGATCCTGTTGGTGGAATTAT
TAAAGATAGAATTGGAGATAACATTCTTGTTGTTGGAGATGCTGCAGGTTTTGTAAATTCTTTAACTGGTGGTGGAATTA
ATTCTGCACTTGAATCTGGTGTATATGCTGGAATTGTTGCAGCTCAAGCTATTAAAGATGGAGATTATAGTAAAAACAAT
CTTAAAGAATATGTTTCATTAACTGATGAACATATTGGTAAACATTATAAGAAATATAATAAAGCTAAAGAATATCTTTT
ATCATTAGAAGATGAAGAACTTGATGAAATTGCTGAAGAATTTGCAAAAGCTGACTTTGAAGAAGTAAATCCAAGAACAT
TAATTAAAATGTTAATTAAGGTTTCACCTAAAGCTTTAGTTAAATTAGGTAAATTATTCTAA

Upstream 100 bases:

>100_bases
GAACTTAAAATCATAATCGATGAAGAAAAATGTACTAAATGTGGATTATGTGTAAAAACATGTCCTGTTGAAGCTTTAAA
ATTAGAATAGGATGATATTC

Downstream 100 bases:

>100_bases
AACTCTTATTTACCCCTTTTTTAAGGAAGATAATATGAAAAATGCAAAAATACCCTGTATAACAGAATTATCCTTACATA
GACCTGAAGTTGTTAGATGG

Product: dehydrogenase

Products: NA

Alternate protein names: DGGGPL reductase 2; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 2; Geranylgeranyl reductase 2; GGR 2

Number of amino acids: Translated: 393; Mature: 393

Protein sequence:

>393_residues
MIETDILVVGAGPSGSLAAKEAALHGADVILIDRKSEIGSPKRCAEGVSKDGLAQLGIKPDPRWIARDLYGVRLVSPNNT
SVWMDNNTIKIPEAGYILERKVFDKHMAMDAARAGAKIMIKTNATSLKRVDDGIIVSTNHMGKDIDIHAKIVIAADGPES
RIGRWAGLECNTEFKYMESCIQFEMAGVNMENNRDIALFFGSVAPGGYVWIFPKGDDIANVGIGVLKNKTNKTAYEHLME
FIKTCPETKDAQPVEINVGGDPVGGIIKDRIGDNILVVGDAAGFVNSLTGGGINSALESGVYAGIVAAQAIKDGDYSKNN
LKEYVSLTDEHIGKHYKKYNKAKEYLLSLEDEELDEIAEEFAKADFEEVNPRTLIKMLIKVSPKALVKLGKLF

Sequences:

>Translated_393_residues
MIETDILVVGAGPSGSLAAKEAALHGADVILIDRKSEIGSPKRCAEGVSKDGLAQLGIKPDPRWIARDLYGVRLVSPNNT
SVWMDNNTIKIPEAGYILERKVFDKHMAMDAARAGAKIMIKTNATSLKRVDDGIIVSTNHMGKDIDIHAKIVIAADGPES
RIGRWAGLECNTEFKYMESCIQFEMAGVNMENNRDIALFFGSVAPGGYVWIFPKGDDIANVGIGVLKNKTNKTAYEHLME
FIKTCPETKDAQPVEINVGGDPVGGIIKDRIGDNILVVGDAAGFVNSLTGGGINSALESGVYAGIVAAQAIKDGDYSKNN
LKEYVSLTDEHIGKHYKKYNKAKEYLLSLEDEELDEIAEEFAKADFEEVNPRTLIKMLIKVSPKALVKLGKLF
>Mature_393_residues
MIETDILVVGAGPSGSLAAKEAALHGADVILIDRKSEIGSPKRCAEGVSKDGLAQLGIKPDPRWIARDLYGVRLVSPNNT
SVWMDNNTIKIPEAGYILERKVFDKHMAMDAARAGAKIMIKTNATSLKRVDDGIIVSTNHMGKDIDIHAKIVIAADGPES
RIGRWAGLECNTEFKYMESCIQFEMAGVNMENNRDIALFFGSVAPGGYVWIFPKGDDIANVGIGVLKNKTNKTAYEHLME
FIKTCPETKDAQPVEINVGGDPVGGIIKDRIGDNILVVGDAAGFVNSLTGGGINSALESGVYAGIVAAQAIKDGDYSKNN
LKEYVSLTDEHIGKHYKKYNKAKEYLLSLEDEELDEIAEEFAKADFEEVNPRTLIKMLIKVSPKALVKLGKLF

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGR2_METST (Q2NFF7)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_448089.1
- ProteinModelPortal:   Q2NFF7
- SMR:   Q2NFF7
- STRING:   Q2NFF7
- GeneID:   3854995
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_1062
- NMPDR:   fig|339860.6.peg.1016
- eggNOG:   arNOG04976
- HOGENOM:   HBG626912
- OMA:   DCGLMAG
- ProtClustDB:   CLSK797878
- BioCyc:   MSTA339860:MSP_1062-MONOMER
- HAMAP:   MF_01287
- InterPro:   IPR011777
- InterPro:   IPR002938
- InterPro:   IPR003042
- PRINTS:   PR00420
- TIGRFAMs:   TIGR02032

Pfam domain/function: PF01494 FAD_binding_3

EC number: NA

Molecular weight: Translated: 42685; Mature: 42685

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETDILVVGAGPSGSLAAKEAALHGADVILIDRKSEIGSPKRCAEGVSKDGLAQLGIKP
CCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEECCHHCCCHHHHHCCCCCCCHHHCCCCC
DPRWIARDLYGVRLVSPNNTSVWMDNNTIKIPEAGYILERKVFDKHMAMDAARAGAKIMI
CCHHHHHHCCEEEEECCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
KTNATSLKRVDDGIIVSTNHMGKDIDIHAKIVIAADGPESRIGRWAGLECNTEFKYMESC
EECCCHHHHCCCCEEEEECCCCCCEEEEEEEEEEECCCHHHCCCEECCCCCCHHHHHHHH
IQFEMAGVNMENNRDIALFFGSVAPGGYVWIFPKGDDIANVGIGVLKNKTNKTAYEHLME
HHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHCCCEEEECCCCHHHHHHHHH
FIKTCPETKDAQPVEINVGGDPVGGIIKDRIGDNILVVGDAAGFVNSLTGGGINSALESG
HHHHCCCCCCCCEEEEECCCCCCCCHHHHHCCCCEEEEECCHHHHHHCCCCCHHHHHHCC
VYAGIVAAQAIKDGDYSKNNLKEYVSLTDEHIGKHYKKYNKAKEYLLSLEDEELDEIAEE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FAKADFEEVNPRTLIKMLIKVSPKALVKLGKLF
HHHCCHHHCCHHHHHHHHHHCCHHHHHHHHCCC
>Mature Secondary Structure
MIETDILVVGAGPSGSLAAKEAALHGADVILIDRKSEIGSPKRCAEGVSKDGLAQLGIKP
CCCCEEEEEECCCCCCCHHHHHHHCCCCEEEEECCHHCCCHHHHHCCCCCCCHHHCCCCC
DPRWIARDLYGVRLVSPNNTSVWMDNNTIKIPEAGYILERKVFDKHMAMDAARAGAKIMI
CCHHHHHHCCEEEEECCCCCEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHCCCEEEE
KTNATSLKRVDDGIIVSTNHMGKDIDIHAKIVIAADGPESRIGRWAGLECNTEFKYMESC
EECCCHHHHCCCCEEEEECCCCCCEEEEEEEEEEECCCHHHCCCEECCCCCCHHHHHHHH
IQFEMAGVNMENNRDIALFFGSVAPGGYVWIFPKGDDIANVGIGVLKNKTNKTAYEHLME
HHHHHCCCCCCCCCEEEEEEECCCCCCEEEEEECCCCCHHCCCEEEECCCCHHHHHHHHH
FIKTCPETKDAQPVEINVGGDPVGGIIKDRIGDNILVVGDAAGFVNSLTGGGINSALESG
HHHHCCCCCCCCEEEEECCCCCCCCHHHHHCCCCEEEEECCHHHHHHCCCCCHHHHHHCC
VYAGIVAAQAIKDGDYSKNNLKEYVSLTDEHIGKHYKKYNKAKEYLLSLEDEELDEIAEE
HHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FAKADFEEVNPRTLIKMLIKVSPKALVKLGKLF
HHHCCHHHCCHHHHHHHHHHCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA