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The map label for this gene is dapL

Identifier: 84489723

GI number: 84489723

Start: 1063608

End: 1064843

Strand: Direct

Name: dapL

Synonym: Msp_0924

Alternate gene names: 84489723

Gene position: 1063608-1064843 (Clockwise)

Preceding gene: 84489722

Following gene: 84489726

Centisome position: 60.18

GC content: 31.39

Gene sequence:

>1236_bases
ATGGCAGTGAAAGTAAATGAATACTATAGTTTAATACAAAACAACTACTTATTTGTAGAAATTGCAAGAAGAGTAGATGA
ATATCAAAAAGAAAATCCAGATGCAAATCTCATAAAAATGGGAATTGGAGATGTAACAAGACCACTTGCAAAATCAGTAG
TTGAAGCATTTAAAAGGGCTGTTGATGAATTAGGTGATGCTGATACATTTAGAGGATATGGTCCAGAACAAGGATATGAC
TTCTTAATTGAAGATGTTATAGAAAATGATTATAAACCATTAGGAGTAGAACTTAAAAACTCTGAAGTATTTATAAGTGA
TGGAGCAAAATGTGATACTGGAAATTTCCAGGAACTCTTTTCTAAAGATAATATAATTGCAGTAACAGATCCTGTATATC
CTGTATATGTTGATAGTAATGTAATGGCAGGACGTAGTGGTAAAATGGGTGAAGATGGATTCTATGAAAACATAGTATAT
CTTCCAGCAACTAGTGAAAATGACTTTGTACCATCACTTCCTAGTGAAAAAGTAGATATTATCTATCTATGTTATCCTAA
CAATCCTACAGGAACAACTCTTACAAAAGAACAATTAAAAGAATGGGTAGATTATGCACATGAAAACGATGCATTAATAT
TATTTGATGCTGCATATGAATCATTTATTAAAACTCCTGGAATTCCACATAGTATCTTTGAAATTGAAGGTGCAAAAGAT
GTTGCAGTTGAATTTAGAAGTTATTCAAAAGTAGCAGGATTTACTGGTACTCGTTGTGCTTACTGTGTTGTACCAGAAGA
GGTTTATGTTAAAGATGCTAATGGTAATAAAGTACAATTAAATCCATTATGGAATAGAAGACAATCAACTAAATTTAATG
GTGTATCATATCCTGTTCAAAGGGCTGCACAGGCAATTTACACACCTGAAGGTAAGAAAGAAATTCAAGAAAATCTTGAT
TATTATGTTAAAAATGCACAAGTTATTCGAGAAAGTCTTGAAAAAATGGGATTAAAAGTTTATGGAGGAGTAGATTCACC
ATATATTTGGTTTAAAACACCTAATGATATTGATTCCTGGAGTTTCTTTGATATTTTACTTAAAGAAGCTCATGTTGTAA
GTACTCCTGGTGCTGGATTTGGTCCAAGTGGAGAAGGTTATCTTAGATTAACTGCATTTAATACTTATGAAAATACTGTT
GAAGCTATGGATAGAATTTCAAAATTAGAATTCTAA

Upstream 100 bases:

>100_bases
GATATGGTACAACTTGAAAGATTTGGATTTGCAAGAGTAGATAAAATAAATGATAATGAAATAACATTCTATTATACACA
TAACTAAAAAGGTGAAATAT

Downstream 100 bases:

>100_bases
TTTTTCTACCATAACTTTTTTTATAAAAAAAAATATTTTACCTAAATTGAGGTGTTTTATGATAAATAAAGCCCTATTTT
TAAGTAAAATTAAGTATTTT

Product: L,L-diaminopimelate aminotransferase

Products: NA

Alternate protein names: DAP-AT; DAP-aminotransferase; LL-DAP-aminotransferase

Number of amino acids: Translated: 411; Mature: 410

Protein sequence:

>411_residues
MAVKVNEYYSLIQNNYLFVEIARRVDEYQKENPDANLIKMGIGDVTRPLAKSVVEAFKRAVDELGDADTFRGYGPEQGYD
FLIEDVIENDYKPLGVELKNSEVFISDGAKCDTGNFQELFSKDNIIAVTDPVYPVYVDSNVMAGRSGKMGEDGFYENIVY
LPATSENDFVPSLPSEKVDIIYLCYPNNPTGTTLTKEQLKEWVDYAHENDALILFDAAYESFIKTPGIPHSIFEIEGAKD
VAVEFRSYSKVAGFTGTRCAYCVVPEEVYVKDANGNKVQLNPLWNRRQSTKFNGVSYPVQRAAQAIYTPEGKKEIQENLD
YYVKNAQVIRESLEKMGLKVYGGVDSPYIWFKTPNDIDSWSFFDILLKEAHVVSTPGAGFGPSGEGYLRLTAFNTYENTV
EAMDRISKLEF

Sequences:

>Translated_411_residues
MAVKVNEYYSLIQNNYLFVEIARRVDEYQKENPDANLIKMGIGDVTRPLAKSVVEAFKRAVDELGDADTFRGYGPEQGYD
FLIEDVIENDYKPLGVELKNSEVFISDGAKCDTGNFQELFSKDNIIAVTDPVYPVYVDSNVMAGRSGKMGEDGFYENIVY
LPATSENDFVPSLPSEKVDIIYLCYPNNPTGTTLTKEQLKEWVDYAHENDALILFDAAYESFIKTPGIPHSIFEIEGAKD
VAVEFRSYSKVAGFTGTRCAYCVVPEEVYVKDANGNKVQLNPLWNRRQSTKFNGVSYPVQRAAQAIYTPEGKKEIQENLD
YYVKNAQVIRESLEKMGLKVYGGVDSPYIWFKTPNDIDSWSFFDILLKEAHVVSTPGAGFGPSGEGYLRLTAFNTYENTV
EAMDRISKLEF
>Mature_410_residues
AVKVNEYYSLIQNNYLFVEIARRVDEYQKENPDANLIKMGIGDVTRPLAKSVVEAFKRAVDELGDADTFRGYGPEQGYDF
LIEDVIENDYKPLGVELKNSEVFISDGAKCDTGNFQELFSKDNIIAVTDPVYPVYVDSNVMAGRSGKMGEDGFYENIVYL
PATSENDFVPSLPSEKVDIIYLCYPNNPTGTTLTKEQLKEWVDYAHENDALILFDAAYESFIKTPGIPHSIFEIEGAKDV
AVEFRSYSKVAGFTGTRCAYCVVPEEVYVKDANGNKVQLNPLWNRRQSTKFNGVSYPVQRAAQAIYTPEGKKEIQENLDY
YVKNAQVIRESLEKMGLKVYGGVDSPYIWFKTPNDIDSWSFFDILLKEAHVVSTPGAGFGPSGEGYLRLTAFNTYENTVE
AMDRISKLEF

Specific function: Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate, a reaction that requires three enzymes in E.coli

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family. LL-diaminopimelate aminotransferase subfamily

Homologues:

Organism=Escherichia coli, GI1788722, Length=319, Percent_Identity=28.2131661442006, Blast_Score=93, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPAT_METST (Q2NFU1)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447955.1
- ProteinModelPortal:   Q2NFU1
- SMR:   Q2NFU1
- STRING:   Q2NFU1
- GeneID:   3856231
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0924
- NMPDR:   fig|339860.6.peg.888
- eggNOG:   arNOG05001
- HOGENOM:   HBG645860
- OMA:   VDLIYLC
- ProtClustDB:   PRK07590
- BioCyc:   MSTA339860:MSP_0924-MONOMER
- HAMAP:   MF_01642
- InterPro:   IPR004839
- InterPro:   IPR019942
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- Gene3D:   G3DSA:3.40.640.10
- Gene3D:   G3DSA:3.90.1150.10
- TIGRFAMs:   TIGR03542

Pfam domain/function: PF00155 Aminotran_1_2; SSF53383 PyrdxlP-dep_Trfase_major

EC number: =2.6.1.83

Molecular weight: Translated: 46292; Mature: 46161

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: BINDING 43-43 BINDING 73-73 BINDING 76-76 BINDING 110-110 BINDING 133-133 BINDING 188-188 BINDING 188-188 BINDING 216-216 BINDING 219-219 BINDING 247-247 BINDING 249-249 BINDING 258-258 BINDING 293-293 BINDING 389-389

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVKVNEYYSLIQNNYLFVEIARRVDEYQKENPDANLIKMGIGDVTRPLAKSVVEAFKRA
CEEEHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHH
VDELGDADTFRGYGPEQGYDFLIEDVIENDYKPLGVELKNSEVFISDGAKCDTGNFQELF
HHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCCCCCHHHHH
SKDNIIAVTDPVYPVYVDSNVMAGRSGKMGEDGFYENIVYLPATSENDFVPSLPSEKVDI
CCCCEEEEECCCEEEEECCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEE
IYLCYPNNPTGTTLTKEQLKEWVDYAHENDALILFDAAYESFIKTPGIPHSIFEIEGAKD
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCCEEEECCCHH
VAVEFRSYSKVAGFTGTRCAYCVVPEEVYVKDANGNKVQLNPLWNRRQSTKFNGVSYPVQ
HHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHH
RAAQAIYTPEGKKEIQENLDYYVKNAQVIRESLEKMGLKVYGGVDSPYIWFKTPNDIDSW
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCH
SFFDILLKEAHVVSTPGAGFGPSGEGYLRLTAFNTYENTVEAMDRISKLEF
HHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVKVNEYYSLIQNNYLFVEIARRVDEYQKENPDANLIKMGIGDVTRPLAKSVVEAFKRA
EEEHHHHHHHHHCCEEEEHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHH
VDELGDADTFRGYGPEQGYDFLIEDVIENDYKPLGVELKNSEVFISDGAKCDTGNFQELF
HHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEECCEEEEECCCCCCCCCHHHHH
SKDNIIAVTDPVYPVYVDSNVMAGRSGKMGEDGFYENIVYLPATSENDFVPSLPSEKVDI
CCCCEEEEECCCEEEEECCCEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCEEE
IYLCYPNNPTGTTLTKEQLKEWVDYAHENDALILFDAAYESFIKTPGIPHSIFEIEGAKD
EEEEECCCCCCCCCCHHHHHHHHHHCCCCCEEEEEHHHHHHHHCCCCCCCCEEEECCCHH
VAVEFRSYSKVAGFTGTRCAYCVVPEEVYVKDANGNKVQLNPLWNRRQSTKFNGVSYPVQ
HHHHHHHHHHHCCCCCCCEEEEEECCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCHHH
RAAQAIYTPEGKKEIQENLDYYVKNAQVIRESLEKMGLKVYGGVDSPYIWFKTPNDIDSW
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEEECCCCCCCH
SFFDILLKEAHVVSTPGAGFGPSGEGYLRLTAFNTYENTVEAMDRISKLEF
HHHHHHHHCCEEEECCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA