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The map label for this gene is fixC [C]

Identifier: 84489673

GI number: 84489673

Start: 1004366

End: 1005577

Strand: Direct

Name: fixC [C]

Synonym: Msp_0874

Alternate gene names: 84489673

Gene position: 1004366-1005577 (Clockwise)

Preceding gene: 84489659

Following gene: 84489678

Centisome position: 56.83

GC content: 32.01

Gene sequence:

>1212_bases
ATGCTAAAAACAGATGTAGTAGTTATTGGAGCAGGTCCTGCAGGATCTATGGCAGCAAAACATGCAGCACTAGGAGGGGC
AAATGTAGTTTTAATAGACAAGAAATCAGAAATTGGAACTCCAAAAAGATGTGCAGAAGGTGTGTATGATGAAGGATTTA
AATGGCTAAATATAGAACCTGATGAAAGATGGATAGCACAGCGTATATATGGTGCAACACTACACTCACCAGATGGAAAT
AGTTTTACAGTAACATCAGAAGATGTACCAGTACAAGGATTTATACTAGAGAGAAAAGTATTTGATAAACACATGGCAAT
GGATGCAGCACGTGCTGGTGCAAAGATAATGATAAAAACATTAGTAACTGATATTAAAAGAAATGAAAATGGATTCATAC
TATCATGTGATTCAATTGAAGGCACAATTGAAGTAGAAGCAAAAATAGCAATCTGTGCAGATGGACCAGAATCAATAATG
GCAAAAAAATTAGGAATTAATTCAACAACACCACAAAACATGATGTCCTGTGCACAATTTGAAATGTGTAATGTAGATTA
TAATGATGATGAAAAAATAGAATTCTACCTAGGACAAGATGTTGCTCTTAAAGGATATGCATGGATATTTCCAAAGGGAA
ATGGTGTTGCAAATGTAGGTCTTGGAGTTACAGGCAATACTGATAAAACAGCATATGAATATATAATGGATTTTATAGAA
AAATGTCCTGCCACAAAGAATGCTCAACCAATAGAAATGAATATAGGTGGAGATCCTATAAATGGACTTATTGAAAAAAT
ATACGATGATAATCTATTAATATGTGGAGATGCTGCAGGTCAAGTAAATCCAATAGAAGGAGGAGGAATTATTGAAGGAA
TGCTTGGTGGTATGGCTGCTGGAGATGTGGCAGCAAAGGCTATTAAAGAAGAAAATTATTCAAAAGAAAGACTTCATGAA
TACTATGAAAAATACAGTGAACTTTCATTTAATTTAATAGAAACACTACCTGCTGCAAGAGATATTGTTTATTCATTTAC
TGATGATGAATATAATAAAATAATAAGTGTAGCAAATACTATAGATTTAAAAAATATATCAAAACGTGATGTATTAAAAG
TAGTATTTAAACTTCCACCAACACTAACAACAAAATTAATTAAATTACTTAAAATTGTATTTCCAAAACAAATGAAAAGT
ATATTGTTTTAG

Upstream 100 bases:

>100_bases
AATAAGTCTACATTATTATAATTAGTAATATTTTTCTATAAAAAAGATATAATATATAATAAATAAAAAAAATATACTAA
GAAAAAAATCGTGATTTATT

Downstream 100 bases:

>100_bases
GTTATGTTTTTAATAAACATCACCTATAATCTTATCTTTAAGTTAATAGGAAGTATGAGTTTTACATATTATTTTATAAA
TATGTTGTTTTAATAAAATT

Product: dehydrogenase

Products: NA

Alternate protein names: DGGGPL reductase 1; 2,3-di-O-geranylgeranylglyceryl phosphate reductase 1; Geranylgeranyl reductase 1; GGR 1

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGTPKRCAEGVYDEGFKWLNIEPDERWIAQRIYGATLHSPDGN
SFTVTSEDVPVQGFILERKVFDKHMAMDAARAGAKIMIKTLVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIM
AKKLGINSTTPQNMMSCAQFEMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEYIMDFIE
KCPATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEGMLGGMAAGDVAAKAIKEENYSKERLHE
YYEKYSELSFNLIETLPAARDIVYSFTDDEYNKIISVANTIDLKNISKRDVLKVVFKLPPTLTTKLIKLLKIVFPKQMKS
ILF

Sequences:

>Translated_403_residues
MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGTPKRCAEGVYDEGFKWLNIEPDERWIAQRIYGATLHSPDGN
SFTVTSEDVPVQGFILERKVFDKHMAMDAARAGAKIMIKTLVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIM
AKKLGINSTTPQNMMSCAQFEMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEYIMDFIE
KCPATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEGMLGGMAAGDVAAKAIKEENYSKERLHE
YYEKYSELSFNLIETLPAARDIVYSFTDDEYNKIISVANTIDLKNISKRDVLKVVFKLPPTLTTKLIKLLKIVFPKQMKS
ILF
>Mature_403_residues
MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGTPKRCAEGVYDEGFKWLNIEPDERWIAQRIYGATLHSPDGN
SFTVTSEDVPVQGFILERKVFDKHMAMDAARAGAKIMIKTLVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIM
AKKLGINSTTPQNMMSCAQFEMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEYIMDFIE
KCPATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEGMLGGMAAGDVAAKAIKEENYSKERLHE
YYEKYSELSFNLIETLPAARDIVYSFTDDEYNKIISVANTIDLKNISKRDVLKVVFKLPPTLTTKLIKLLKIVFPKQMKS
ILF

Specific function: Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2

COG id: COG0644

COG function: function code C; Dehydrogenases (flavoproteins)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the geranylgeranyl reductase family. DGGGPL reductase subfamily

Homologues:

Organism=Escherichia coli, GI1786227, Length=370, Percent_Identity=24.0540540540541, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GGR1_METST (Q2NFZ1)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447905.1
- ProteinModelPortal:   Q2NFZ1
- SMR:   Q2NFZ1
- GeneID:   3854860
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0874
- NMPDR:   fig|339860.6.peg.840
- eggNOG:   arNOG04976
- HOGENOM:   HBG626912
- ProtClustDB:   CLSK797878
- BioCyc:   MSTA339860:MSP_0874-MONOMER
- HAMAP:   MF_01287
- InterPro:   IPR013027
- InterPro:   IPR011777
- InterPro:   IPR003042
- PRINTS:   PR00420
- TIGRFAMs:   TIGR02032

Pfam domain/function: PF07992 Pyr_redox_2

EC number: NA

Molecular weight: Translated: 44093; Mature: 44093

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGTPKRCAEGVYDEGFKWLNIEP
CCCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCHHHCCCEEEECCC
DERWIAQRIYGATLHSPDGNSFTVTSEDVPVQGFILERKVFDKHMAMDAARAGAKIMIKT
HHHHHHHHHHCCEEECCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHH
LVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIMAKKLGINSTTPQNMMSCAQF
HHHHHHCCCCCEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHH
EMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEYIMDFIE
HEECCCCCCCCEEEEEECCCEEECCEEEEEECCCCEEEECEEECCCCCHHHHHHHHHHHH
KCPATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEGMLGGMAA
HCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCHH
GDVAAKAIKEENYSKERLHEYYEKYSELSFNLIETLPAARDIVYSFTDDEYNKIISVANT
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHEEEECCCHHHHHHHHHHHH
IDLKNISKRDVLKVVFKLPPTLTTKLIKLLKIVFPKQMKSILF
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKTDVVVIGAGPAGSMAAKHAALGGANVVLIDKKSEIGTPKRCAEGVYDEGFKWLNIEP
CCCCCEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCHHHHHCCHHHCCCEEEECCC
DERWIAQRIYGATLHSPDGNSFTVTSEDVPVQGFILERKVFDKHMAMDAARAGAKIMIKT
HHHHHHHHHHCCEEECCCCCEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHCCHHHHHHH
LVTDIKRNENGFILSCDSIEGTIEVEAKIAICADGPESIMAKKLGINSTTPQNMMSCAQF
HHHHHHCCCCCEEEEECCCCCEEEEEEEEEEECCCHHHHHHHHCCCCCCCHHHHHHHHHH
EMCNVDYNDDEKIEFYLGQDVALKGYAWIFPKGNGVANVGLGVTGNTDKTAYEYIMDFIE
HEECCCCCCCCEEEEEECCCEEECCEEEEEECCCCEEEECEEECCCCCHHHHHHHHHHHH
KCPATKNAQPIEMNIGGDPINGLIEKIYDDNLLICGDAAGQVNPIEGGGIIEGMLGGMAA
HCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEEECCCCCCCCCCCCCHHHHHHCCCHH
GDVAAKAIKEENYSKERLHEYYEKYSELSFNLIETLPAARDIVYSFTDDEYNKIISVANT
HHHHHHHHHHCCCCHHHHHHHHHHHHHCCHHHHHHCCCHHHEEEECCCHHHHHHHHHHHH
IDLKNISKRDVLKVVFKLPPTLTTKLIKLLKIVFPKQMKSILF
CCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on NADH or NADPH; With a quinone or similar compound as acceptor [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA