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The map label for this gene is aspC

Identifier: 84488964

GI number: 84488964

Start: 154806

End: 156125

Strand: Direct

Name: aspC

Synonym: Msp_0135

Alternate gene names: 84488964

Gene position: 154806-156125 (Clockwise)

Preceding gene: 84488963

Following gene: 84488967

Centisome position: 8.76

GC content: 32.12

Gene sequence:

>1320_bases
GTGACAGACATATTTGAAAAATGTAAAAGAACCCATTACTCAAATGAAATAGGTCCAGAACTTGCTGGTGAAACAGTTAA
AGTAACTGGATGGGTACATGAAATAAGAGATCTTGGTGGAATTGTATTTGTATTAATCAGAGATAAAAATGGTATAACAC
AATTAACAGCACCAAGTAAAAAATTATCTGAAGAAATGATGGCAGATGTACGTGCAGCAAGAAAAGAAACAATAATTACC
CTAACAGGTACTGTACAAGAATCAGCAAAAGCACCTAATGGTGTTGAAATAATTCCAAGTAACATTGATGTAATTAATGT
TTCACAATTACCTCTACCATTAGATACTACAGAAAAAGTAGAAGCAGAAATGGATACAAGATTAGATTCAAGATTCATGG
ATTTAAGAAAACATGATGTAAGTGCAATATTTAAAATAAAAAGTCAAATGTTACACACAGCACGTAACTACTTCTATGAC
AATGATTTTACAGAAATCACAACACCAAAACTTGTAGCTTCAGCAACTGAAGGTGGAACAGAATTATTCCCAATAACCTA
CTTTGAAAAAGAAGCATTTCTTGGACAAAGTCCTCAACTATATAAACAAATGATGATGGCAACAGGTCTTGACAATGTAT
TTGAAATAGGACAAATATTCAGAGCAGAAGAACATGATACATTAAGACATTTAAATGAAGCATTATCCATTGATGCAGAA
ATGTCATTTAAAAGTCAAACAGATGCAATGAACACATTAGAAGAATTAATTAAAAGAATATTATCAGACATATCTACTAA
TTGTCAAAAAGAATTATCTGACTTAGATCATGAATTAGATATTCCTACAGAACCATTCCCAATAGTTACATATGAAGAAG
TAATTGATATTGTAAATAGTAGGGATGTTGAAATGAATTATGGTGAAGATTTAAATAGGGCAGCAGAAAAAGTATTAGGA
GAAACTATGGGTAGTTACTACTTTATTACAGAATGGCCAACAGCAATTAAACCATTCTATGTAATGCCTAACAGTGATGA
TGCTGAAAAAAGCACTGCATTTGATTTAATGTACAGAGATCTTGAATTGTCAAGTGGTGCACAACGTATCCATGATTATG
ATCTTTTATACAGTCAAATAGAAGCAAAAGATTTAAATCCTGATTCATTTGAAAAATACTTACAAGCATTTAAGTATGGT
ATGCCACCACACTCTGGTTGGGGTATGGGTGCAGACAGATTAACAATGGTTATTACAGGTGCAAAAAATATTAGGGAAAC
TGTATTATTCCCAAGAGACAGAAGACGACTTACACCTTAG

Upstream 100 bases:

>100_bases
TTTTCTATTAAATAAATTTATCAATTAAGAAAAATATAAATATATATTAATATTTTATTAATTTTAACTAAAATCATAAA
ATGAATACATAGGTGAAAAA

Downstream 100 bases:

>100_bases
TTGTTCTTCTTTATTTTTTTTTAAATTAATTTCTTTTTCTAAAATAAGTATGATAAAATAAGTTTGTCTATTTTTAATAA
ATTTAATAAAAAAAGAGGTA

Product: aspartyl-tRNA synthetase

Products: NA

Alternate protein names: Aspartate--tRNA ligase; AspRS

Number of amino acids: Translated: 439; Mature: 438

Protein sequence:

>439_residues
MTDIFEKCKRTHYSNEIGPELAGETVKVTGWVHEIRDLGGIVFVLIRDKNGITQLTAPSKKLSEEMMADVRAARKETIIT
LTGTVQESAKAPNGVEIIPSNIDVINVSQLPLPLDTTEKVEAEMDTRLDSRFMDLRKHDVSAIFKIKSQMLHTARNYFYD
NDFTEITTPKLVASATEGGTELFPITYFEKEAFLGQSPQLYKQMMMATGLDNVFEIGQIFRAEEHDTLRHLNEALSIDAE
MSFKSQTDAMNTLEELIKRILSDISTNCQKELSDLDHELDIPTEPFPIVTYEEVIDIVNSRDVEMNYGEDLNRAAEKVLG
ETMGSYYFITEWPTAIKPFYVMPNSDDAEKSTAFDLMYRDLELSSGAQRIHDYDLLYSQIEAKDLNPDSFEKYLQAFKYG
MPPHSGWGMGADRLTMVITGAKNIRETVLFPRDRRRLTP

Sequences:

>Translated_439_residues
MTDIFEKCKRTHYSNEIGPELAGETVKVTGWVHEIRDLGGIVFVLIRDKNGITQLTAPSKKLSEEMMADVRAARKETIIT
LTGTVQESAKAPNGVEIIPSNIDVINVSQLPLPLDTTEKVEAEMDTRLDSRFMDLRKHDVSAIFKIKSQMLHTARNYFYD
NDFTEITTPKLVASATEGGTELFPITYFEKEAFLGQSPQLYKQMMMATGLDNVFEIGQIFRAEEHDTLRHLNEALSIDAE
MSFKSQTDAMNTLEELIKRILSDISTNCQKELSDLDHELDIPTEPFPIVTYEEVIDIVNSRDVEMNYGEDLNRAAEKVLG
ETMGSYYFITEWPTAIKPFYVMPNSDDAEKSTAFDLMYRDLELSSGAQRIHDYDLLYSQIEAKDLNPDSFEKYLQAFKYG
MPPHSGWGMGADRLTMVITGAKNIRETVLFPRDRRRLTP
>Mature_438_residues
TDIFEKCKRTHYSNEIGPELAGETVKVTGWVHEIRDLGGIVFVLIRDKNGITQLTAPSKKLSEEMMADVRAARKETIITL
TGTVQESAKAPNGVEIIPSNIDVINVSQLPLPLDTTEKVEAEMDTRLDSRFMDLRKHDVSAIFKIKSQMLHTARNYFYDN
DFTEITTPKLVASATEGGTELFPITYFEKEAFLGQSPQLYKQMMMATGLDNVFEIGQIFRAEEHDTLRHLNEALSIDAEM
SFKSQTDAMNTLEELIKRILSDISTNCQKELSDLDHELDIPTEPFPIVTYEEVIDIVNSRDVEMNYGEDLNRAAEKVLGE
TMGSYYFITEWPTAIKPFYVMPNSDDAEKSTAFDLMYRDLELSSGAQRIHDYDLLYSQIEAKDLNPDSFEKYLQAFKYGM
PPHSGWGMGADRLTMVITGAKNIRETVLFPRDRRRLTP

Specific function: Unknown

COG id: COG0017

COG function: function code J; Aspartyl/asparaginyl-tRNA synthetases

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II aminoacyl-tRNA synthetase family

Homologues:

Organism=Homo sapiens, GI45439306, Length=448, Percent_Identity=33.0357142857143, Blast_Score=268, Evalue=8e-72,
Organism=Homo sapiens, GI4758762, Length=431, Percent_Identity=29.6983758700696, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI226491502, Length=441, Percent_Identity=26.984126984127, Blast_Score=155, Evalue=6e-38,
Organism=Homo sapiens, GI5031815, Length=486, Percent_Identity=26.3374485596708, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI194272210, Length=486, Percent_Identity=26.3374485596708, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI40789249, Length=309, Percent_Identity=27.831715210356, Blast_Score=112, Evalue=6e-25,
Organism=Escherichia coli, GI1787161, Length=446, Percent_Identity=25.5605381165919, Blast_Score=128, Evalue=9e-31,
Organism=Escherichia coli, GI1788173, Length=315, Percent_Identity=29.2063492063492, Blast_Score=125, Evalue=4e-30,
Organism=Escherichia coli, GI1789256, Length=478, Percent_Identity=24.6861924686192, Blast_Score=118, Evalue=6e-28,
Organism=Escherichia coli, GI1790571, Length=453, Percent_Identity=24.7240618101545, Blast_Score=106, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17551876, Length=471, Percent_Identity=33.1210191082803, Blast_Score=270, Evalue=1e-72,
Organism=Caenorhabditis elegans, GI71984122, Length=431, Percent_Identity=30.6264501160093, Blast_Score=200, Evalue=1e-51,
Organism=Caenorhabditis elegans, GI17556372, Length=406, Percent_Identity=24.6305418719212, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI71994340, Length=467, Percent_Identity=25.2676659528908, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17535925, Length=467, Percent_Identity=25.2676659528908, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17535927, Length=467, Percent_Identity=25.2676659528908, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI32566633, Length=294, Percent_Identity=25.5102040816327, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6323011, Length=451, Percent_Identity=33.2594235033259, Blast_Score=243, Evalue=4e-65,
Organism=Saccharomyces cerevisiae, GI6321807, Length=436, Percent_Identity=31.651376146789, Blast_Score=218, Evalue=2e-57,
Organism=Saccharomyces cerevisiae, GI6319872, Length=457, Percent_Identity=26.2582056892779, Blast_Score=139, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6325153, Length=260, Percent_Identity=28.8461538461538, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17136276, Length=453, Percent_Identity=32.8918322295806, Blast_Score=257, Evalue=1e-68,
Organism=Drosophila melanogaster, GI19921528, Length=433, Percent_Identity=29.3302540415704, Blast_Score=188, Evalue=6e-48,
Organism=Drosophila melanogaster, GI19922416, Length=449, Percent_Identity=24.2761692650334, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24640851, Length=472, Percent_Identity=26.6949152542373, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24640849, Length=471, Percent_Identity=26.7515923566879, Blast_Score=112, Evalue=5e-25,
Organism=Drosophila melanogaster, GI24584738, Length=317, Percent_Identity=27.7602523659306, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 80 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): SYD_METST (Q2NHT0)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447196.1
- ProteinModelPortal:   Q2NHT0
- SMR:   Q2NHT0
- STRING:   Q2NHT0
- GeneID:   3855027
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0135
- NMPDR:   fig|339860.6.peg.133
- eggNOG:   arNOG04316
- HOGENOM:   HBG745843
- OMA:   ASAFPRD
- PhylomeDB:   Q2NHT0
- ProtClustDB:   PRK05159
- BioCyc:   MSTA339860:MSP_0135-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00044_A
- InterPro:   IPR004364
- InterPro:   IPR018150
- InterPro:   IPR006195
- InterPro:   IPR020780
- InterPro:   IPR004523
- InterPro:   IPR002312
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR004365
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR22594
- PRINTS:   PR01042
- TIGRFAMs:   TIGR00458

Pfam domain/function: PF00152 tRNA-synt_2; PF01336 tRNA_anti; SSF50249 Nucleic_acid_OB

EC number: =6.1.1.12

Molecular weight: Translated: 49924; Mature: 49793

Theoretical pI: Translated: 4.53; Mature: 4.53

Prosite motif: PS50862 AA_TRNA_LIGASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIFEKCKRTHYSNEIGPELAGETVKVTGWVHEIRDLGGIVFVLIRDKNGITQLTAPSK
CCHHHHHHHHHCCCCCCCHHHCCCEEEEHHHHHHHHHCCCEEEEEEECCCCCEEECCCHH
KLSEEMMADVRAARKETIITLTGTVQESAKAPNGVEIIPSNIDVINVSQLPLPLDTTEKV
HHHHHHHHHHHHHHHCEEEEEECCHHHHCCCCCCCEEECCCCCEEEECCCCCCCCCHHHH
EAEMDTRLDSRFMDLRKHDVSAIFKIKSQMLHTARNYFYDNDFTEITTPKLVASATEGGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
ELFPITYFEKEAFLGQSPQLYKQMMMATGLDNVFEIGQIFRAEEHDTLRHLNEALSIDAE
EEEEEEEECHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
MSFKSQTDAMNTLEELIKRILSDISTNCQKELSDLDHELDIPTEPFPIVTYEEVIDIVNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHCC
RDVEMNYGEDLNRAAEKVLGETMGSYYFITEWPTAIKPFYVMPNSDDAEKSTAFDLMYRD
CCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHH
LELSSGAQRIHDYDLLYSQIEAKDLNPDSFEKYLQAFKYGMPPHSGWGMGADRLTMVITG
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
AKNIRETVLFPRDRRRLTP
CHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TDIFEKCKRTHYSNEIGPELAGETVKVTGWVHEIRDLGGIVFVLIRDKNGITQLTAPSK
CHHHHHHHHHCCCCCCCHHHCCCEEEEHHHHHHHHHCCCEEEEEEECCCCCEEECCCHH
KLSEEMMADVRAARKETIITLTGTVQESAKAPNGVEIIPSNIDVINVSQLPLPLDTTEKV
HHHHHHHHHHHHHHHCEEEEEECCHHHHCCCCCCCEEECCCCCEEEECCCCCCCCCHHHH
EAEMDTRLDSRFMDLRKHDVSAIFKIKSQMLHTARNYFYDNDFTEITTPKLVASATEGGT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCC
ELFPITYFEKEAFLGQSPQLYKQMMMATGLDNVFEIGQIFRAEEHDTLRHLNEALSIDAE
EEEEEEEECHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCC
MSFKSQTDAMNTLEELIKRILSDISTNCQKELSDLDHELDIPTEPFPIVTYEEVIDIVNS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEHHHHHHHHCC
RDVEMNYGEDLNRAAEKVLGETMGSYYFITEWPTAIKPFYVMPNSDDAEKSTAFDLMYRD
CCCCCCCCCHHHHHHHHHHHHHHCCEEEEECCCCCCCCEEECCCCCCCHHHHHHHHHHHH
LELSSGAQRIHDYDLLYSQIEAKDLNPDSFEKYLQAFKYGMPPHSGWGMGADRLTMVITG
HHHCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEC
AKNIRETVLFPRDRRRLTP
CHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA