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The map label for this gene is gcp

Identifier: 84488844

GI number: 84488844

Start: 15048

End: 16652

Strand: Direct

Name: gcp

Synonym: Msp_0013

Alternate gene names: 84488844

Gene position: 15048-16652 (Clockwise)

Preceding gene: 84488832

Following gene: 84488848

Centisome position: 0.85

GC content: 30.97

Gene sequence:

>1605_bases
TTGATTTGTCTAGGAATAGAGGGTACAGCAGAAAAGTGTGGTATTGGTATTGTGGACTCTGATGGAAATATATTAGCTAC
TTGTGGATGTCAACTTTATCCAGAAGTAGGTGGAATTCATCCAAGGGAAGCAGCAAATTTTCATGCAGAACACATTGTAC
CTTTAATTAGAGAGGCACTTGAAGAGTCAAATTTATCTATTAATGATATTGACTTAGTGTCTTTTGCAAAGGGTCCTGGT
CTTGGACCAGCTTTAAGAACTGTTGCAACTGCTGCAAGAAGTTTATCTCAAAATATTGGGGTGCCGTTAATCGGTGTAAA
TCATTGTATAGGGCATGTGGAGATTGGGAAATTAACAACTGGAGCTAAAGATCCTTTAACATTATATACAAGTGGTGGTA
ATACTCAAATAATTAGTTATGAATCTGGAAGATATAGGATTATTGGAGAAACATTGGACATTGCAATTGGTAACTGTTTA
GATCAGTTTTCAAGGGATATTGGTTTAGGACATCCTGGAGGACCTATTGTTGAAAAACATGCAGAAAATACTAATAAAAC
AATAGAATTACCCTATGTTGTTAAAGGTATGGATTTATCCTTCTCTGGAATTTTAACTAGTGCTATTAATAAGTATAAAC
AAGGTGTTGACTTAGATGTAATATGTAATAGTTTTCAACAAACATGTTTTGCAATGCTTTGTGAGGTAACAGAAAGGGCA
ATAAGTTACACTGGAAAGAATGAAGTGTTGTTATGTGGAGGTGTTGCTGCAAATAGTAAGTTACGTCAGATGCTACAAGT
TATGTGTGAGGATCATTATGTTGACTTTTACATGCCTCCTATGAAGTATTGTGGTGATAATGGTTCTATGATAGCAAGAG
TGGGTCTTTTATCATATGATGAGAATAAATGTGGTATAGAAAATAGTTATATTAATCCAAAGTATAGAACAGATCAAGTA
GAAGTTACATGGATAAAAGATAACTTTCAGCATAATATAAATCTCCCTGATAATATTAAAGAAAAAGGTGCTGAAGCCGA
TATAATTGAAGGTATTTGGGATGAGAGAGAAGTTATTATAAAACATCGTGTTAAAAAGAAATATCGTGTAGATAAACTAG
ATGAAAAATTAAGATTAGAGAGAACTAAAGAAGAAGCAAAATTACTCTCTGATTGTAAAAAATATGGAGTAACAACACCC
TATATCTATTCAATAGATCTTAATAGAAAAGATATTATTCTAGAAAAAATAGATGCTCCTAAGTTACATGAAATAATAAA
TACTGATAAAGATATAAAGAAAATATTTACAAATATTGGAGAAATGGTTTTTAAAATGCATGAAGGTGAAATAATTCATG
GGGATCTAACAACAGCTAACATACTCATAAAAGATGATAAACCAATATTCATTGATTTTGGACTAGGAAAGTATAGTAAT
CTCTTAGAAGATAAAGGAACAGATCTACTTGTATTTAAAAAATCATTAAATACAATAATTCCAGAAAAATCAGAAGAACT
ATTTAATTACTTCTTAAATGGTTATGATAATGAAGATGTAATTAAAAAAATAGATGAAATTGAAAAAAGAGGAAGATACC
TCTAA

Upstream 100 bases:

>100_bases
CATTACTTATCTATACGATTATATTATTAAATATAGTATCAAGATATAATAATAGTTATTAATTATTTTTAAAGAATAAT
TTAAATGGAGAGAACATTAA

Downstream 100 bases:

>100_bases
ATTTTTTTTATAATACCACTGATAATATAATTGTTATAATACCTATTATTGTACAATAGTATGCAAAAATATCTAAACTC
CAACCTTTAATCATTTTCAT

Product: O-sialoglycoprotein endopeptidase/protein kinase

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MICLGIEGTAEKCGIGIVDSDGNILATCGCQLYPEVGGIHPREAANFHAEHIVPLIREALEESNLSINDIDLVSFAKGPG
LGPALRTVATAARSLSQNIGVPLIGVNHCIGHVEIGKLTTGAKDPLTLYTSGGNTQIISYESGRYRIIGETLDIAIGNCL
DQFSRDIGLGHPGGPIVEKHAENTNKTIELPYVVKGMDLSFSGILTSAINKYKQGVDLDVICNSFQQTCFAMLCEVTERA
ISYTGKNEVLLCGGVAANSKLRQMLQVMCEDHYVDFYMPPMKYCGDNGSMIARVGLLSYDENKCGIENSYINPKYRTDQV
EVTWIKDNFQHNINLPDNIKEKGAEADIIEGIWDEREVIIKHRVKKKYRVDKLDEKLRLERTKEEAKLLSDCKKYGVTTP
YIYSIDLNRKDIILEKIDAPKLHEIINTDKDIKKIFTNIGEMVFKMHEGEIIHGDLTTANILIKDDKPIFIDFGLGKYSN
LLEDKGTDLLVFKKSLNTIIPEKSEELFNYFLNGYDNEDVIKKIDEIEKRGRYL

Sequences:

>Translated_534_residues
MICLGIEGTAEKCGIGIVDSDGNILATCGCQLYPEVGGIHPREAANFHAEHIVPLIREALEESNLSINDIDLVSFAKGPG
LGPALRTVATAARSLSQNIGVPLIGVNHCIGHVEIGKLTTGAKDPLTLYTSGGNTQIISYESGRYRIIGETLDIAIGNCL
DQFSRDIGLGHPGGPIVEKHAENTNKTIELPYVVKGMDLSFSGILTSAINKYKQGVDLDVICNSFQQTCFAMLCEVTERA
ISYTGKNEVLLCGGVAANSKLRQMLQVMCEDHYVDFYMPPMKYCGDNGSMIARVGLLSYDENKCGIENSYINPKYRTDQV
EVTWIKDNFQHNINLPDNIKEKGAEADIIEGIWDEREVIIKHRVKKKYRVDKLDEKLRLERTKEEAKLLSDCKKYGVTTP
YIYSIDLNRKDIILEKIDAPKLHEIINTDKDIKKIFTNIGEMVFKMHEGEIIHGDLTTANILIKDDKPIFIDFGLGKYSN
LLEDKGTDLLVFKKSLNTIIPEKSEELFNYFLNGYDNEDVIKKIDEIEKRGRYL
>Mature_534_residues
MICLGIEGTAEKCGIGIVDSDGNILATCGCQLYPEVGGIHPREAANFHAEHIVPLIREALEESNLSINDIDLVSFAKGPG
LGPALRTVATAARSLSQNIGVPLIGVNHCIGHVEIGKLTTGAKDPLTLYTSGGNTQIISYESGRYRIIGETLDIAIGNCL
DQFSRDIGLGHPGGPIVEKHAENTNKTIELPYVVKGMDLSFSGILTSAINKYKQGVDLDVICNSFQQTCFAMLCEVTERA
ISYTGKNEVLLCGGVAANSKLRQMLQVMCEDHYVDFYMPPMKYCGDNGSMIARVGLLSYDENKCGIENSYINPKYRTDQV
EVTWIKDNFQHNINLPDNIKEKGAEADIIEGIWDEREVIIKHRVKKKYRVDKLDEKLRLERTKEEAKLLSDCKKYGVTTP
YIYSIDLNRKDIILEKIDAPKLHEIINTDKDIKKIFTNIGEMVFKMHEGEIIHGDLTTANILIKDDKPIFIDFGLGKYSN
LLEDKGTDLLVFKKSLNTIIPEKSEELFNYFLNGYDNEDVIKKIDEIEKRGRYL

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 protein kinase domain

Homologues:

Organism=Homo sapiens, GI8923380, Length=330, Percent_Identity=44.5454545454545, Blast_Score=282, Evalue=6e-76,
Organism=Homo sapiens, GI41327715, Length=209, Percent_Identity=33.9712918660287, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI116812636, Length=341, Percent_Identity=27.8592375366569, Blast_Score=107, Evalue=2e-23,
Organism=Escherichia coli, GI1789445, Length=332, Percent_Identity=34.6385542168675, Blast_Score=171, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI71995670, Length=336, Percent_Identity=43.1547619047619, Blast_Score=271, Evalue=7e-73,
Organism=Caenorhabditis elegans, GI17557464, Length=324, Percent_Identity=26.5432098765432, Blast_Score=83, Evalue=4e-16,
Organism=Saccharomyces cerevisiae, GI6322891, Length=368, Percent_Identity=39.945652173913, Blast_Score=257, Evalue=3e-69,
Organism=Saccharomyces cerevisiae, GI6320099, Length=375, Percent_Identity=28, Blast_Score=110, Evalue=7e-25,
Organism=Saccharomyces cerevisiae, GI6321701, Length=212, Percent_Identity=29.7169811320755, Blast_Score=84, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21357207, Length=348, Percent_Identity=45.4022988505747, Blast_Score=299, Evalue=3e-81,
Organism=Drosophila melanogaster, GI24658177, Length=215, Percent_Identity=36.2790697674419, Blast_Score=115, Evalue=9e-26,
Organism=Drosophila melanogaster, GI20129063, Length=341, Percent_Identity=24.633431085044, Blast_Score=93, Evalue=4e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_METST (Q2NIA4)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447076.1
- ProteinModelPortal:   Q2NIA4
- SMR:   Q2NIA4
- STRING:   Q2NIA4
- MEROPS:   M22.003
- GeneID:   3855639
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0013
- NMPDR:   fig|339860.6.peg.14
- eggNOG:   arNOG04080
- HOGENOM:   HBG304663
- OMA:   GNCLDQF
- PhylomeDB:   Q2NIA4
- ProtClustDB:   PRK09605
- BioCyc:   MSTA339860:MSP_0013-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01447
- InterPro:   IPR022449
- InterPro:   IPR022495
- InterPro:   IPR011009
- InterPro:   IPR009220
- InterPro:   IPR000905
- InterPro:   IPR017861
- InterPro:   IPR000719
- InterPro:   IPR018934
- InterPro:   IPR008266
- PANTHER:   PTHR11735
- PIRSF:   PIRSF036401
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03724
- TIGRFAMs:   TIGR03722
- TIGRFAMs:   TIGR00329

Pfam domain/function: PF00814 Peptidase_M22; PF01163 RIO1; SSF56112 Kinase_like

EC number: =3.4.24.57

Molecular weight: Translated: 59652; Mature: 59652

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS01016 GLYCOPROTEASE; PS50011 PROTEIN_KINASE_DOM; PS00109 PROTEIN_KINASE_TYR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MICLGIEGTAEKCGIGIVDSDGNILATCGCQLYPEVGGIHPREAANFHAEHIVPLIREAL
CEEECCCCCHHHCCEEEEECCCCEEEEECCEECCCCCCCCCCHHCCCCHHHHHHHHHHHH
EESNLSINDIDLVSFAKGPGLGPALRTVATAARSLSQNIGVPLIGVNHCIGHVEIGKLTT
HHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEECCCCC
GAKDPLTLYTSGGNTQIISYESGRYRIIGETLDIAIGNCLDQFSRDIGLGHPGGPIVEKH
CCCCCEEEEECCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AENTNKTIELPYVVKGMDLSFSGILTSAINKYKQGVDLDVICNSFQQTCFAMLCEVTERA
CCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
ISYTGKNEVLLCGGVAANSKLRQMLQVMCEDHYVDFYMPPMKYCGDNGSMIARVGLLSYD
HHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCEEEEEEEEEEC
ENKCGIENSYINPKYRTDQVEVTWIKDNFQHNINLPDNIKEKGAEADIIEGIWDEREVII
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHCCCCCHHHHHHCCHHHHHH
KHRVKKKYRVDKLDEKLRLERTKEEAKLLSDCKKYGVTTPYIYSIDLNRKDIILEKIDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCC
KLHEIINTDKDIKKIFTNIGEMVFKMHEGEIIHGDLTTANILIKDDKPIFIDFGLGKYSN
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCEEEEEECCCHHHH
LLEDKGTDLLVFKKSLNTIIPEKSEELFNYFLNGYDNEDVIKKIDEIEKRGRYL
HHHCCCCEEEEEECHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MICLGIEGTAEKCGIGIVDSDGNILATCGCQLYPEVGGIHPREAANFHAEHIVPLIREAL
CEEECCCCCHHHCCEEEEECCCCEEEEECCEECCCCCCCCCCHHCCCCHHHHHHHHHHHH
EESNLSINDIDLVSFAKGPGLGPALRTVATAARSLSQNIGVPLIGVNHCIGHVEIGKLTT
HHCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCEEEHHHCCCCEEECCCCC
GAKDPLTLYTSGGNTQIISYESGRYRIIGETLDIAIGNCLDQFSRDIGLGHPGGPIVEKH
CCCCCEEEEECCCCEEEEEECCCCEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
AENTNKTIELPYVVKGMDLSFSGILTSAINKYKQGVDLDVICNSFQQTCFAMLCEVTERA
CCCCCCEEECCEEEECCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHH
ISYTGKNEVLLCGGVAANSKLRQMLQVMCEDHYVDFYMPPMKYCGDNGSMIARVGLLSYD
HHCCCCCCEEEECCCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCEEEEEEEEEEC
ENKCGIENSYINPKYRTDQVEVTWIKDNFQHNINLPDNIKEKGAEADIIEGIWDEREVII
CCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCHHHCCCCCHHHHHHCCHHHHHH
KHRVKKKYRVDKLDEKLRLERTKEEAKLLSDCKKYGVTTPYIYSIDLNRKDIILEKIDAP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCEEEECCCCC
KLHEIINTDKDIKKIFTNIGEMVFKMHEGEIIHGDLTTANILIKDDKPIFIDFGLGKYSN
HHHHHHCCCHHHHHHHHHHHHHHHHHCCCEEEECCCCEEEEEEECCCEEEEEECCCHHHH
LLEDKGTDLLVFKKSLNTIIPEKSEELFNYFLNGYDNEDVIKKIDEIEKRGRYL
HHHCCCCEEEEEECHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA