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The map label for this gene is cdc6-1

Identifier: 84488832

GI number: 84488832

Start: 718

End: 1872

Strand: Direct

Name: cdc6-1

Synonym: Msp_0001

Alternate gene names: 84488832

Gene position: 718-1872 (Clockwise)

Preceding gene: NA

Following gene: 84488844

Centisome position: 0.04

GC content: 28.14

Gene sequence:

>1155_bases
ATGAATAATATATTTAAAACAATCAACAATAAAGATTCGATATTTTTAACAAAAAAATACCTTGATCATAGATTTATACC
TGAAACTCTACCTCACAGAGATGAAAAAATTAAATCCATTGCTCAATATTGGGTAGAATCACTTGATAAAATAACACCTC
CTGACATTACCATTTACGGTAAAACAGGAACTGGTAAAACAGCTGTTACACTCTATGCTAAAAAACAGTTAGAAGAAGTA
GCTGCTGAACAAAATCTAAATATTCGTGTCGAATACATTCGTTGTACTGATTATAATACAGAATATCAGATACTTGCACG
TTTATGTCAACAATTAGGAAAACCTGTTCCATATAGAGGATGGACAAAAGCAGAAGTAGTAAATGCTTTTAGAAATTTAT
TTAAGAAAAATATTCTTGGTGAAGATTTAATTTTAATAGTAATTTTAGATGAAGTGGATGTTATTCTTAAAAATGATGGA
GACAATATATTATACACATTAACACGTACTGATAACGTAGCAATTACATCAATAAGTAATTATATTGACTTTAAACAATT
CATTAAACCTAAAGTAAAAAGTAGTTTAAGAGATAGGGAAATTGTATTTCCTCCATACAATGCACAACAATTAATAGATA
TTCTAAAAGAAAGATCAAAAGTATCCTTCAGTGAAGGAGCAATATCTGAAGGTGTAATAGCATTATGTTCTGCACTTGCT
GCAAAAGAAGAAGGAGATGCACGTTATGCTCTTGATTTATTAAAAACATCTGGGGAAATTGCAGATGAAAAAGAATCTTC
TGTTATTGAAGAAAGTTTCGTAAAAGAAGCAAAAGATCGTATTGAACATAGTAAAATAATAGATGTTGTTGTAACACTTC
CAATTCAACAACAAAAAGTTCTTGAATCAATAACTTACTTAACAAAAAAACGAGAAGAAATAACTTCTGGAAGATTATAT
GAAGTTTATCAAGATCTAGCTAAGAATGATAAAGTATCTTATAGAAGAATCTTTGATTTTATTAATGAATTAGAAATGTT
AGGTTTAATTTCTACAAATACAATCTCTAGGGGAAGAGGTAAGGGACGAACAAATATTATCACACTTCAATGTGATATAG
AATTAATAGATAAAGCATTAATATATAAAGATTAA

Upstream 100 bases:

>100_bases
ATTAAATAGAAAATATTAATTATTTAATTTTTCACTTGAATTTATATTACTACCAATATAAATATACTTGAAATACATCT
AAGATTCTTTGGAGGATAAA

Downstream 100 bases:

>100_bases
TTCTTTATCTACTATTTTTTATTATACTATTTTTATTATTAATTATCTATTGTTTAATTTGATTTAATCATTGTTAATAC
CATTTTAAATCTTTCTTTTG

Product: cell division control protein 6-like 1

Products: NA

Alternate protein names: CDC6 homolog

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MNNIFKTINNKDSIFLTKKYLDHRFIPETLPHRDEKIKSIAQYWVESLDKITPPDITIYGKTGTGKTAVTLYAKKQLEEV
AAEQNLNIRVEYIRCTDYNTEYQILARLCQQLGKPVPYRGWTKAEVVNAFRNLFKKNILGEDLILIVILDEVDVILKNDG
DNILYTLTRTDNVAITSISNYIDFKQFIKPKVKSSLRDREIVFPPYNAQQLIDILKERSKVSFSEGAISEGVIALCSALA
AKEEGDARYALDLLKTSGEIADEKESSVIEESFVKEAKDRIEHSKIIDVVVTLPIQQQKVLESITYLTKKREEITSGRLY
EVYQDLAKNDKVSYRRIFDFINELEMLGLISTNTISRGRGKGRTNIITLQCDIELIDKALIYKD

Sequences:

>Translated_384_residues
MNNIFKTINNKDSIFLTKKYLDHRFIPETLPHRDEKIKSIAQYWVESLDKITPPDITIYGKTGTGKTAVTLYAKKQLEEV
AAEQNLNIRVEYIRCTDYNTEYQILARLCQQLGKPVPYRGWTKAEVVNAFRNLFKKNILGEDLILIVILDEVDVILKNDG
DNILYTLTRTDNVAITSISNYIDFKQFIKPKVKSSLRDREIVFPPYNAQQLIDILKERSKVSFSEGAISEGVIALCSALA
AKEEGDARYALDLLKTSGEIADEKESSVIEESFVKEAKDRIEHSKIIDVVVTLPIQQQKVLESITYLTKKREEITSGRLY
EVYQDLAKNDKVSYRRIFDFINELEMLGLISTNTISRGRGKGRTNIITLQCDIELIDKALIYKD
>Mature_384_residues
MNNIFKTINNKDSIFLTKKYLDHRFIPETLPHRDEKIKSIAQYWVESLDKITPPDITIYGKTGTGKTAVTLYAKKQLEEV
AAEQNLNIRVEYIRCTDYNTEYQILARLCQQLGKPVPYRGWTKAEVVNAFRNLFKKNILGEDLILIVILDEVDVILKNDG
DNILYTLTRTDNVAITSISNYIDFKQFIKPKVKSSLRDREIVFPPYNAQQLIDILKERSKVSFSEGAISEGVIALCSALA
AKEEGDARYALDLLKTSGEIADEKESSVIEESFVKEAKDRIEHSKIIDVVVTLPIQQQKVLESITYLTKKREEITSGRLY
EVYQDLAKNDKVSYRRIFDFINELEMLGLISTNTISRGRGKGRTNIITLQCDIELIDKALIYKD

Specific function: Might be involved in the initiation of DNA replication

COG id: COG1474

COG function: function code LO; Cdc6-related protein, AAA superfamily ATPase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDC6/cdc18 family

Homologues:

Organism=Homo sapiens, GI4502703, Length=363, Percent_Identity=22.8650137741047, Blast_Score=81, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555708, Length=317, Percent_Identity=27.1293375394322, Blast_Score=72, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17506005, Length=236, Percent_Identity=27.1186440677966, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21355681, Length=400, Percent_Identity=22.75, Blast_Score=84, Evalue=2e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CDC6_METST (Q2NIC5)

Other databases:

- EMBL:   CP000102
- RefSeq:   YP_447064.1
- ProteinModelPortal:   Q2NIC5
- SMR:   Q2NIC5
- STRING:   Q2NIC5
- GeneID:   3855931
- GenomeReviews:   CP000102_GR
- KEGG:   mst:Msp_0001
- NMPDR:   fig|339860.6.peg.1
- eggNOG:   arNOG04006
- HOGENOM:   HBG553472
- OMA:   IPMTGWP
- ProtClustDB:   CLSK798166
- BioCyc:   MSTA339860:MSP_0001-MONOMER
- HAMAP:   MF_01407
- InterPro:   IPR003959
- InterPro:   IPR015163
- InterPro:   IPR014277
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PANTHER:   PTHR10763:SF8
- TIGRFAMs:   TIGR02928

Pfam domain/function: PF00004 AAA; PF09079 Cdc6_C

EC number: NA

Molecular weight: Translated: 43978; Mature: 43978

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.5 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNNIFKTINNKDSIFLTKKYLDHRFIPETLPHRDEKIKSIAQYWVESLDKITPPDITIYG
CCCHHHHCCCCCCEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
KTGTGKTAVTLYAKKQLEEVAAEQNLNIRVEYIRCTDYNTEYQILARLCQQLGKPVPYRG
CCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
WTKAEVVNAFRNLFKKNILGEDLILIVILDEVDVILKNDGDNILYTLTRTDNVAITSISN
CHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEEHHH
YIDFKQFIKPKVKSSLRDREIVFPPYNAQQLIDILKERSKVSFSEGAISEGVIALCSALA
HHHHHHHHCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AKEEGDARYALDLLKTSGEIADEKESSVIEESFVKEAKDRIEHSKIIDVVVTLPIQQQKV
HCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHH
LESITYLTKKREEITSGRLYEVYQDLAKNDKVSYRRIFDFINELEMLGLISTNTISRGRG
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KGRTNIITLQCDIELIDKALIYKD
CCCCEEEEEEECHHHHHHHHHCCC
>Mature Secondary Structure
MNNIFKTINNKDSIFLTKKYLDHRFIPETLPHRDEKIKSIAQYWVESLDKITPPDITIYG
CCCHHHHCCCCCCEEEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEE
KTGTGKTAVTLYAKKQLEEVAAEQNLNIRVEYIRCTDYNTEYQILARLCQQLGKPVPYRG
CCCCCCEEEEHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
WTKAEVVNAFRNLFKKNILGEDLILIVILDEVDVILKNDGDNILYTLTRTDNVAITSISN
CHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCEEEEECCCCCEEEEEEECCCEEEEEHHH
YIDFKQFIKPKVKSSLRDREIVFPPYNAQQLIDILKERSKVSFSEGAISEGVIALCSALA
HHHHHHHHCHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AKEEGDARYALDLLKTSGEIADEKESSVIEESFVKEAKDRIEHSKIIDVVVTLPIQQQKV
HCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHH
LESITYLTKKREEITSGRLYEVYQDLAKNDKVSYRRIFDFINELEMLGLISTNTISRGRG
HHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
KGRTNIITLQCDIELIDKALIYKD
CCCCEEEEEEECHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA