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The map label for this gene is gudP [H]

Identifier: 83721570

GI number: 83721570

Start: 217652

End: 219007

Strand: Direct

Name: gudP [H]

Synonym: BTH_I0187

Alternate gene names: 83721570

Gene position: 217652-219007 (Clockwise)

Preceding gene: 83720460

Following gene: 83720349

Centisome position: 5.71

GC content: 65.71

Gene sequence:

>1356_bases
ATGGACATCAAGGCTCCCGCCGTGGGTGCGCGCAGCACGCCGCGCGTGGAGCGCATGAGCCGCGTGCGCTTCACGATTCT
CGCGATGCTGTTCGTCGTGACGACGATCAACTACGCGGACCGCGCGACGATCTCGATCGCCGGCTCGGCGATGCAAAAGG
ACCTCGGCATCGACGCGGTATCGCTCGGCTACATCTTCTCCGCGTTCGGCTGGGCGTATGTGATCGCGCAGATTCCGGGC
GGATGGCTTCTCGATCGTTTCGGGTCACGACGCGTTTATGCGGCGAGCATCCTGACGTGGTCGGTCTTCACGCTCGCGCA
AGGCGCGATCGGCCTGTTCACCGGCATGGCCGCGATCGTGGCGGTGTTCTCGCTGCGCTTTCTCGTCGGCATCGCGGAAG
CGCCTTCGTTTCCGGCGAACAGCCGGATCGTCGCCGCGTGGTTTCCGGCGAACGAGCGCGGCACGGCTTCCGCGATCTTC
AACTCCGCGCAATACGCGGCGACGGTGATCTTCGCGCCGCTGATGGCGTGGCTCGTGCATCGCTTCGGCTGGCACGAAGT
GTTCGTCGTGATGGGGGCGATCGGCATCGCGGCGGCGTTCGCGTGGCGCGCCGTCGTACGCGATCCGAAGGATCATCCGC
GCATGAACCGCGCGGAGATCGAGTACATCGAGAACGGCGGCGGCCTCGTCAACATGGATCGCGCGGGCGTCGCGAACGCG
CAGGGCCCCGACCTCGGCTACATCGGGCAGTTGCTGAAGAACCGGATGATGATGGGCGTCTACGTCGCGCAATACTGCAT
CAACGCGCTCACGTACTTCTTCATCACGTGGTTCCCGGTGTACCTCGTGCAGGCGCGCGGGATGTCGATCCTGAAGGCGG
GCTTCGTCGCGTCGGTGCCCGCCGTGTGCGGCTTCCTCGGCGGCATTCTGGGCGGCATCGTCTCCGATGCGCTGCTGCGC
CGCGGCGCGTCGCTGTCGGTTGCACGCAAGGTGCCGATCGTGCTCGGCATGCTGCTGTCGGTCAGCATGGTGGTGTGCAA
TTACGTCGACACGCAGGGCATCGTCGTCGCGGTCATGGCGCTCGCGTTCTTTGGCAAGGGCATGGGCGCGCTCGGCTGGG
CGGTCAATTCGGATACCGCGCCGAAGCAGATCGCGGGCCTGTCGGGGGCATTGATGAACACGTTCGGCAACCTGTCGAGC
ATCACCACGCCGATCGCGATCGGCTACATCGTCAACCGGACCGGCTCGTTCAACGGCGCGCTGGCCTACGTGGGGCTTCA
TGCGCTCGTCGCGTGCGTCTGCTACCTGTTCGTGGTCGGCGAGATCAAGCGCGTCGAGCTGAAGCCGGCATCGTGA

Upstream 100 bases:

>100_bases
GGTCTGATCGCGATGGTCTCGCGAAGCCGGGCCGCAGCGGGCCCGGCGCCGAAAGCTGAAACGACCGGCGCATAATGGAT
GCCGGCGGAAGGAGGAGACA

Downstream 100 bases:

>100_bases
AGCGAGGCATGTCGAACATGACGTCGAATGCGATCGAAGCCGCCGCGCAAGCGCACGCGAACACGCACACGCCGAGCCCG
AGCGTCGCGCAACGGTGCGA

Product: major facilitator superfamily transporter phthalate permease

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 451; Mature: 451

Protein sequence:

>451_residues
MDIKAPAVGARSTPRVERMSRVRFTILAMLFVVTTINYADRATISIAGSAMQKDLGIDAVSLGYIFSAFGWAYVIAQIPG
GWLLDRFGSRRVYAASILTWSVFTLAQGAIGLFTGMAAIVAVFSLRFLVGIAEAPSFPANSRIVAAWFPANERGTASAIF
NSAQYAATVIFAPLMAWLVHRFGWHEVFVVMGAIGIAAAFAWRAVVRDPKDHPRMNRAEIEYIENGGGLVNMDRAGVANA
QGPDLGYIGQLLKNRMMMGVYVAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFLGGILGGIVSDALLR
RGASLSVARKVPIVLGMLLSVSMVVCNYVDTQGIVVAVMALAFFGKGMGALGWAVNSDTAPKQIAGLSGALMNTFGNLSS
ITTPIAIGYIVNRTGSFNGALAYVGLHALVACVCYLFVVGEIKRVELKPAS

Sequences:

>Translated_451_residues
MDIKAPAVGARSTPRVERMSRVRFTILAMLFVVTTINYADRATISIAGSAMQKDLGIDAVSLGYIFSAFGWAYVIAQIPG
GWLLDRFGSRRVYAASILTWSVFTLAQGAIGLFTGMAAIVAVFSLRFLVGIAEAPSFPANSRIVAAWFPANERGTASAIF
NSAQYAATVIFAPLMAWLVHRFGWHEVFVVMGAIGIAAAFAWRAVVRDPKDHPRMNRAEIEYIENGGGLVNMDRAGVANA
QGPDLGYIGQLLKNRMMMGVYVAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFLGGILGGIVSDALLR
RGASLSVARKVPIVLGMLLSVSMVVCNYVDTQGIVVAVMALAFFGKGMGALGWAVNSDTAPKQIAGLSGALMNTFGNLSS
ITTPIAIGYIVNRTGSFNGALAYVGLHALVACVCYLFVVGEIKRVELKPAS
>Mature_451_residues
MDIKAPAVGARSTPRVERMSRVRFTILAMLFVVTTINYADRATISIAGSAMQKDLGIDAVSLGYIFSAFGWAYVIAQIPG
GWLLDRFGSRRVYAASILTWSVFTLAQGAIGLFTGMAAIVAVFSLRFLVGIAEAPSFPANSRIVAAWFPANERGTASAIF
NSAQYAATVIFAPLMAWLVHRFGWHEVFVVMGAIGIAAAFAWRAVVRDPKDHPRMNRAEIEYIENGGGLVNMDRAGVANA
QGPDLGYIGQLLKNRMMMGVYVAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVPAVCGFLGGILGGIVSDALLR
RGASLSVARKVPIVLGMLLSVSMVVCNYVDTQGIVVAVMALAFFGKGMGALGWAVNSDTAPKQIAGLSGALMNTFGNLSS
ITTPIAIGYIVNRTGSFNGALAYVGLHALVACVCYLFVVGEIKRVELKPAS

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI9966811, Length=386, Percent_Identity=29.0155440414508, Blast_Score=125, Evalue=5e-29,
Organism=Homo sapiens, GI9945322, Length=358, Percent_Identity=28.2122905027933, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI6912666, Length=376, Percent_Identity=27.3936170212766, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI21322234, Length=389, Percent_Identity=25.706940874036, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI148743791, Length=360, Percent_Identity=24.1666666666667, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI4885441, Length=367, Percent_Identity=26.7029972752044, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI223718438, Length=202, Percent_Identity=28.7128712871287, Blast_Score=86, Evalue=7e-17,
Organism=Homo sapiens, GI154350196, Length=421, Percent_Identity=22.3277909738717, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI148728191, Length=301, Percent_Identity=23.5880398671096, Blast_Score=78, Evalue=1e-14,
Organism=Homo sapiens, GI256219598, Length=395, Percent_Identity=23.0379746835443, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4503847, Length=395, Percent_Identity=23.0379746835443, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI256219483, Length=395, Percent_Identity=23.0379746835443, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI5031955, Length=287, Percent_Identity=24.7386759581882, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI256219543, Length=314, Percent_Identity=23.2484076433121, Blast_Score=72, Evalue=9e-13,
Organism=Escherichia coli, GI1789152, Length=445, Percent_Identity=65.6179775280899, Blast_Score=612, Evalue=1e-176,
Organism=Escherichia coli, GI1789515, Length=430, Percent_Identity=58.6046511627907, Blast_Score=546, Evalue=1e-156,
Organism=Escherichia coli, GI87082320, Length=428, Percent_Identity=40.1869158878505, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI2367379, Length=442, Percent_Identity=28.5067873303167, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI2367193, Length=338, Percent_Identity=27.2189349112426, Blast_Score=132, Evalue=6e-32,
Organism=Escherichia coli, GI1788573, Length=466, Percent_Identity=22.9613733905579, Blast_Score=75, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI115533556, Length=396, Percent_Identity=27.7777777777778, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI115533554, Length=396, Percent_Identity=27.7777777777778, Blast_Score=118, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17552542, Length=448, Percent_Identity=24.1071428571429, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17560030, Length=355, Percent_Identity=23.3802816901408, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17535049, Length=413, Percent_Identity=22.2760290556901, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI32565914, Length=264, Percent_Identity=24.2424242424242, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI25151055, Length=240, Percent_Identity=23.75, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI32565916, Length=264, Percent_Identity=24.2424242424242, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193205400, Length=316, Percent_Identity=21.2025316455696, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=394, Percent_Identity=22.0812182741117, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25141316, Length=394, Percent_Identity=22.0812182741117, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17570335, Length=244, Percent_Identity=25, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554148, Length=346, Percent_Identity=22.8323699421965, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=332, Percent_Identity=22.289156626506, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI71997452, Length=353, Percent_Identity=23.7960339943343, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI86561091, Length=276, Percent_Identity=24.2753623188406, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17569727, Length=415, Percent_Identity=22.6506024096386, Blast_Score=65, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24639764, Length=436, Percent_Identity=25.6880733944954, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641682, Length=377, Percent_Identity=27.5862068965517, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24583789, Length=414, Percent_Identity=26.3285024154589, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24648416, Length=472, Percent_Identity=25, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI21356189, Length=472, Percent_Identity=25, Blast_Score=109, Evalue=4e-24,
Organism=Drosophila melanogaster, GI19922400, Length=452, Percent_Identity=25, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI62484226, Length=444, Percent_Identity=25.9009009009009, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24654215, Length=437, Percent_Identity=24.9427917620137, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI45550460, Length=410, Percent_Identity=24.6341463414634, Blast_Score=103, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28573299, Length=407, Percent_Identity=24.8157248157248, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24655255, Length=370, Percent_Identity=24.8648648648649, Blast_Score=100, Evalue=3e-21,
Organism=Drosophila melanogaster, GI20130167, Length=454, Percent_Identity=25.3303964757709, Blast_Score=97, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24584153, Length=350, Percent_Identity=24.2857142857143, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI20130135, Length=413, Percent_Identity=23.4866828087167, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24655271, Length=413, Percent_Identity=23.4866828087167, Blast_Score=90, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24580790, Length=355, Percent_Identity=25.3521126760563, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI20129235, Length=371, Percent_Identity=25.0673854447439, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI28573708, Length=436, Percent_Identity=23.6238532110092, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI28573707, Length=436, Percent_Identity=23.6238532110092, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24658658, Length=402, Percent_Identity=23.6318407960199, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI24653727, Length=315, Percent_Identity=26.6666666666667, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI221474708, Length=192, Percent_Identity=32.2916666666667, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24658666, Length=412, Percent_Identity=22.5728155339806, Blast_Score=75, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24658674, Length=382, Percent_Identity=23.0366492146597, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI281361682, Length=357, Percent_Identity=22.6890756302521, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI19920686, Length=390, Percent_Identity=23.5897435897436, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 48106; Mature: 48106

Theoretical pI: Translated: 10.01; Mature: 10.01

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDIKAPAVGARSTPRVERMSRVRFTILAMLFVVTTINYADRATISIAGSAMQKDLGIDAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHH
SLGYIFSAFGWAYVIAQIPGGWLLDRFGSRRVYAASILTWSVFTLAQGAIGLFTGMAAIV
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVFSLRFLVGIAEAPSFPANSRIVAAWFPANERGTASAIFNSAQYAATVIFAPLMAWLVH
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RFGWHEVFVVMGAIGIAAAFAWRAVVRDPKDHPRMNRAEIEYIENGGGLVNMDRAGVANA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCEEEECCCCCCCC
QGPDLGYIGQLLKNRMMMGVYVAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AVCGFLGGILGGIVSDALLRRGASLSVARKVPIVLGMLLSVSMVVCNYVDTQGIVVAVMA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LAFFGKGMGALGWAVNSDTAPKQIAGLSGALMNTFGNLSSITTPIAIGYIVNRTGSFNGA
HHHHCCCCCHHCEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCH
LAYVGLHALVACVCYLFVVGEIKRVELKPAS
HHHHHHHHHHHHHHHHHHHCCHHEEEECCCC
>Mature Secondary Structure
MDIKAPAVGARSTPRVERMSRVRFTILAMLFVVTTINYADRATISIAGSAMQKDLGIDAV
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEHHHHHHHCCCCHH
SLGYIFSAFGWAYVIAQIPGGWLLDRFGSRRVYAASILTWSVFTLAQGAIGLFTGMAAIV
HHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVFSLRFLVGIAEAPSFPANSRIVAAWFPANERGTASAIFNSAQYAATVIFAPLMAWLVH
HHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
RFGWHEVFVVMGAIGIAAAFAWRAVVRDPKDHPRMNRAEIEYIENGGGLVNMDRAGVANA
HCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHEEECCCCEEEECCCCCCCC
QGPDLGYIGQLLKNRMMMGVYVAQYCINALTYFFITWFPVYLVQARGMSILKAGFVASVP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
AVCGFLGGILGGIVSDALLRRGASLSVARKVPIVLGMLLSVSMVVCNYVDTQGIVVAVMA
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
LAFFGKGMGALGWAVNSDTAPKQIAGLSGALMNTFGNLSSITTPIAIGYIVNRTGSFNGA
HHHHCCCCCHHCEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEECCCCCCCH
LAYVGLHALVACVCYLFVVGEIKRVELKPAS
HHHHHHHHHHHHHHHHHHHCCHHEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9772162; 10762278 [H]