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The map label for this gene is lrp [H]

Identifier: 83721544

GI number: 83721544

Start: 351216

End: 351674

Strand: Reverse

Name: lrp [H]

Synonym: BTH_I0319

Alternate gene names: 83721544

Gene position: 351674-351216 (Counterclockwise)

Preceding gene: 83719807

Following gene: 83720177

Centisome position: 9.23

GC content: 62.96

Gene sequence:

>459_bases
ATGAAACTTGACGCCATCGACCGGCGCATCCTGCAAGCGCTGCAACGCGACGGCCGGCTGCAGAACGTGGAGCTCGCCAA
GGAAGTCGGCCTGTCGCCTTCGCCGTGCCTCAGACGGGTCCGGCTGCTCGAGGAAGCCGGCGTGATCGAACGGTACGTCG
CGGTGCTCAATCCCGCGAAGGTCGGCCGAGGATTGACCGTGTTCACGCGCGTCTGGCTCAAAGAGCAGGATGCGGACACC
GTCGATCACTTCGCCGCCGCGGTCCAGCAGTTGCCGCAGGTCGTCGAGTGCCACCTGATGGCGGGCGACTGCGATTTCCT
GTTGCGCGTCGTCGCCGCCGACATCGACGACTATAGGCAGTTCCAGATGCATCACCTGACGCGGATCAAGGGCGTGCAAA
GCGTGAAAACCGAGATTCCGCTGCAAAAGGTGAAGTTGACGTCGGAAGTGCCGGTTTGA

Upstream 100 bases:

>100_bases
TCTGCCAAAATCGATGAAATCGGGTTGCGTTGTTGCCATATGCCGATGTTGAATTGGCACGAACAACCTATTTCTCTCAT
ATTCCTGGAATTGAATTCCA

Downstream 100 bases:

>100_bases
AGGTTTGAAGGTCCGATGCCCCGGGCGCGCCGCGCGCTCGCCCCAGGCCTCGCACCGCGCCATGACGTGAGCATCGGCGG
CGTCGACGTTCCCCCCTCTC

Product: transcription regulator AsnC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 152; Mature: 152

Protein sequence:

>152_residues
MKLDAIDRRILQALQRDGRLQNVELAKEVGLSPSPCLRRVRLLEEAGVIERYVAVLNPAKVGRGLTVFTRVWLKEQDADT
VDHFAAAVQQLPQVVECHLMAGDCDFLLRVVAADIDDYRQFQMHHLTRIKGVQSVKTEIPLQKVKLTSEVPV

Sequences:

>Translated_152_residues
MKLDAIDRRILQALQRDGRLQNVELAKEVGLSPSPCLRRVRLLEEAGVIERYVAVLNPAKVGRGLTVFTRVWLKEQDADT
VDHFAAAVQQLPQVVECHLMAGDCDFLLRVVAADIDDYRQFQMHHLTRIKGVQSVKTEIPLQKVKLTSEVPV
>Mature_152_residues
MKLDAIDRRILQALQRDGRLQNVELAKEVGLSPSPCLRRVRLLEEAGVIERYVAVLNPAKVGRGLTVFTRVWLKEQDADT
VDHFAAAVQQLPQVVECHLMAGDCDFLLRVVAADIDDYRQFQMHHLTRIKGVQSVKTEIPLQKVKLTSEVPV

Specific function: Mediates a global response to leucine. Exogenous leucine affects the expression of a number of different operons; lrp mediates this effect for at least some of these operons. For example it is regulator of the branched-chain amino acid transport genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787116, Length=148, Percent_Identity=44.5945945945946, Blast_Score=136, Evalue=7e-34,
Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=33.3333333333333, Blast_Score=103, Evalue=3e-24,
Organism=Escherichia coli, GI1790182, Length=141, Percent_Identity=29.0780141843972, Blast_Score=64, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg [H]

EC number: NA

Molecular weight: Translated: 17165; Mature: 17165

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLDAIDRRILQALQRDGRLQNVELAKEVGLSPSPCLRRVRLLEEAGVIERYVAVLNPAK
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
VGRGLTVFTRVWLKEQDADTVDHFAAAVQQLPQVVECHLMAGDCDFLLRVVAADIDDYRQ
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FQMHHLTRIKGVQSVKTEIPLQKVKLTSEVPV
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC
>Mature Secondary Structure
MKLDAIDRRILQALQRDGRLQNVELAKEVGLSPSPCLRRVRLLEEAGVIERYVAVLNPAK
CCCHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCHHH
VGRGLTVFTRVWLKEQDADTVDHFAAAVQQLPQVVECHLMAGDCDFLLRVVAADIDDYRQ
HCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
FQMHHLTRIKGVQSVKTEIPLQKVKLTSEVPV
HHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]