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The map label for this gene is dapA-1 [H]

Identifier: 83719807

GI number: 83719807

Start: 353927

End: 354814

Strand: Reverse

Name: dapA-1 [H]

Synonym: BTH_I0323

Alternate gene names: 83719807

Gene position: 354814-353927 (Counterclockwise)

Preceding gene: 83720168

Following gene: 83721544

Centisome position: 9.31

GC content: 70.72

Gene sequence:

>888_bases
ATGCAATCACGTTTCGAAGGTATCTGGCTGCCGATCGTCACGCCGTTTCGCGCGGGCGAAATCGACCATCCGTCGCTCGC
GCGCCTCGCCCGGCACTATGCGGACGAAGGCATCGCGGGCTTCGTCGCAGGCGCGACGACGGGCGAAGGCGCGCTCCTCG
ACGCGGGCGAACAGGAAGCGATTTTCGCGACGCTGCGCGACGCCGCGCCGACGCATCCGATCGTGCTCGGCATCTCCGCG
AGCGCGACGCACGCGGCCGCCAAGCGCGCGCGCGAACTCGCGGCGCTCGGCCCGAACGGGCTGCTCGTCACGCCGCCCGT
CTACGTCCGGCCGACGCAGGCAGGCGTGCGGCGGCACTTCGAAGCAATCGTCGAAGCGGCGGATCTGCCCGTGCTCGTCT
ACAACATTCCGTACCGCACCGGCGTAAGCGTCGAGCTCGACACGCTGCAGGCGCTGTCGCGCGATGCACGCGTCGTCGGC
GTGAAGGAGTGCGGCGGGACGATCGAGCGGATGCTGCGTCTCGTGCACGAAACGCCGCTGCGCATCCTCTCCGGCGACGA
CAACCAGAATTTCGCGGCGCTGTGCGCGGGCGCGCATGGCGCGATCGCGAGCGCCGCGCACGTGCTGCCCGCATGGCACG
TGCGCGTGCAAGCACTGCTGCGCGAAGGCCGGCTCGACGATGCGCGGCGGATCGCGGTCGCACTGCGGCCGCTCGTCGCC
GATCTGTTCGCGGAGCCGAATCCCGCGCCCGTGAAGGCGCTGCTCGCCGCGCAAGGCTGGTGCGACAACGCGCTGCGGTT
GCCGTTCCTGCCGGTGAGCGATGCGCTCGCGGCGCGGTTGATCGCGCATTGGGAAGCGCTGCGGCAGAGCGAGACCGCCG
ACGTCTGA

Upstream 100 bases:

>100_bases
GGACGGGATGCCCGCGTGTTGACTCACTCTTCGCATACCTCGATCCGGCGCCGGCCGGCAGGACGGTTCCCCCTCCACCC
GTTTCACCTAGAGGATGCAC

Downstream 100 bases:

>100_bases
GCGAATCGGATTGCGTCGATCAGGGGCATGTGCGCGATGTGGCGTGGCGACGGTTCGAATGTGTCGATTCGGGCGTCGCT
TTATCGAGCGATGCGTGGTT

Product: dihydrodipicolinate synthase

Products: NA

Alternate protein names: DHDPS [H]

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MQSRFEGIWLPIVTPFRAGEIDHPSLARLARHYADEGIAGFVAGATTGEGALLDAGEQEAIFATLRDAAPTHPIVLGISA
SATHAAAKRARELAALGPNGLLVTPPVYVRPTQAGVRRHFEAIVEAADLPVLVYNIPYRTGVSVELDTLQALSRDARVVG
VKECGGTIERMLRLVHETPLRILSGDDNQNFAALCAGAHGAIASAAHVLPAWHVRVQALLREGRLDDARRIAVALRPLVA
DLFAEPNPAPVKALLAAQGWCDNALRLPFLPVSDALAARLIAHWEALRQSETADV

Sequences:

>Translated_295_residues
MQSRFEGIWLPIVTPFRAGEIDHPSLARLARHYADEGIAGFVAGATTGEGALLDAGEQEAIFATLRDAAPTHPIVLGISA
SATHAAAKRARELAALGPNGLLVTPPVYVRPTQAGVRRHFEAIVEAADLPVLVYNIPYRTGVSVELDTLQALSRDARVVG
VKECGGTIERMLRLVHETPLRILSGDDNQNFAALCAGAHGAIASAAHVLPAWHVRVQALLREGRLDDARRIAVALRPLVA
DLFAEPNPAPVKALLAAQGWCDNALRLPFLPVSDALAARLIAHWEALRQSETADV
>Mature_295_residues
MQSRFEGIWLPIVTPFRAGEIDHPSLARLARHYADEGIAGFVAGATTGEGALLDAGEQEAIFATLRDAAPTHPIVLGISA
SATHAAAKRARELAALGPNGLLVTPPVYVRPTQAGVRRHFEAIVEAADLPVLVYNIPYRTGVSVELDTLQALSRDARVVG
VKECGGTIERMLRLVHETPLRILSGDDNQNFAALCAGAHGAIASAAHVLPAWHVRVQALLREGRLDDARRIAVALRPLVA
DLFAEPNPAPVKALLAAQGWCDNALRLPFLPVSDALAARLIAHWEALRQSETADV

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; first step. [C]

COG id: COG0329

COG function: function code EM; Dihydrodipicolinate synthase/N-acetylneuraminate lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DHDPS family [H]

Homologues:

Organism=Homo sapiens, GI31543060, Length=288, Percent_Identity=26.7361111111111, Blast_Score=104, Evalue=9e-23,
Organism=Escherichia coli, GI1788823, Length=276, Percent_Identity=34.0579710144928, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789620, Length=294, Percent_Identity=25.5102040816327, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1786463, Length=227, Percent_Identity=25.5506607929515, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI87082415, Length=233, Percent_Identity=23.6051502145923, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR005263
- InterPro:   IPR002220
- InterPro:   IPR020625
- InterPro:   IPR020624 [H]

Pfam domain/function: PF00701 DHDPS [H]

EC number: =4.2.1.52 [H]

Molecular weight: Translated: 31489; Mature: 31489

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00666 DHDPS_2 ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQSRFEGIWLPIVTPFRAGEIDHPSLARLARHYADEGIAGFVAGATTGEGALLDAGEQEA
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCHH
IFATLRDAAPTHPIVLGISASATHAAAKRARELAALGPNGLLVTPPVYVRPTQAGVRRHF
HHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEECCHHHHHHHH
EAIVEAADLPVLVYNIPYRTGVSVELDTLQALSRDARVVGVKECGGTIERMLRLVHETPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHCCC
RILSGDDNQNFAALCAGAHGAIASAAHVLPAWHVRVQALLREGRLDDARRIAVALRPLVA
EEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DLFAEPNPAPVKALLAAQGWCDNALRLPFLPVSDALAARLIAHWEALRQSETADV
HHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MQSRFEGIWLPIVTPFRAGEIDHPSLARLARHYADEGIAGFVAGATTGEGALLDAGEQEA
CCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCEECCCCCHH
IFATLRDAAPTHPIVLGISASATHAAAKRARELAALGPNGLLVTPPVYVRPTQAGVRRHF
HHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEEECCCCEEECCHHHHHHHH
EAIVEAADLPVLVYNIPYRTGVSVELDTLQALSRDARVVGVKECGGTIERMLRLVHETPL
HHHHHHCCCCEEEEECCCCCCCCEEHHHHHHHCCCCEEEEHHHCCHHHHHHHHHHHHCCC
RILSGDDNQNFAALCAGAHGAIASAAHVLPAWHVRVQALLREGRLDDARRIAVALRPLVA
EEEECCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
DLFAEPNPAPVKALLAAQGWCDNALRLPFLPVSDALAARLIAHWEALRQSETADV
HHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]