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The map label for this gene is ada [H]

Identifier: 83721464

GI number: 83721464

Start: 90583

End: 91614

Strand: Direct

Name: ada [H]

Synonym: BTH_I0086

Alternate gene names: 83721464

Gene position: 90583-91614 (Clockwise)

Preceding gene: 83720827

Following gene: 83719941

Centisome position: 2.38

GC content: 74.13

Gene sequence:

>1032_bases
TTGGGGCTTGCCGCGCAAGGCGGCGCTCCTCGATGCCGAAGCGCAGCGCGCGGCGCGCGAATCCGTCGAGCCCGCCGTGG
ACGACGCCGCTTGAGCGCCGCCGTCGAATCGGCCGTCGTGCCGTCCGGCAGCGTCGTGTTCGAGCTGCCGTTCAAACCTC
CATATGATTGGCCGCGCGTGCTGCGCTTCTTCGCGGGGCGCGCGATCCCGGGCGTCGAGGCGGTCGAGGGCGGCGCGTAC
CGGCGCACGGTCGACTATCGCGGCGCGGTCGGGGCGTTGACGGTGCGCAAGCATCCGCGCAAGCGCTGTCTCGTCGCCAC
CGTCGAAGGCGACGCAGCGCGGCACGCGGACGCAGCATTCGCCGCGCGGCTTGCGACGATGTTCGATCTGCATGCCGATC
CCGCCGCGATCGGCGCGCATCTCGCGCGCGACGCATGGCTCGCGCCGCTCGTCGACGCCGCGCCTGGCCTGCGCGTGCCG
GGCGCGTGGTCGAGCTTCGAGCTGATCGTGCGCGCGATCGTCGGCCAGCAGGTGAGCGTGAAGGCCGCGACGACGATCGT
CGGGCGGCTTGTCGAGCGCGCGGGCGAGCGGCTTGTCGGGCACGCACCGGGCGCGACCGGCTGGCGGTTTCCCGAGCCTG
CCGCGCTTGCCGCGTGCGACTTGTCGCGAATCGGGATGCCGGGCAAGCGCGCCGCGGCGCTGCAGGGCGTTGCGCGCGCG
GTCGCCGCGGGCGACGTGCCGCTCGATGCGTACGCGACCGATCCGGCCGGCGTGCGCGCCGCGCTGCTCGCGCTGCCGGG
AATCGGCCCGTGGACCGTCGAATATGTCGCGATGCGCGCATGGCGCGATGCCGACGCTTGGCCCGCGACCGATCTCGTGC
TGATGCAGGCGATCGTCGCGCGCGACCCGGCGCTCGACCGGCCGGCGAGCCAGCGTCTGCGCGCCGATGCGTGGCGGCCG
TGGCGCGCGTATGCGGCGATGCATCTGTGGAACGAGATCGCCGATCGCGCCGGTTCGGCGCGCGGCGGATAG

Upstream 100 bases:

>100_bases
CGGTGCGGGCGGTCGCGAGCGCGTGCGCGTCGAATCCGGTGGCGCTCGCGATCCCGTGCCACCGCGTCGTGCAGAAGGGC
GGCTCGCTTGCCGGCTACCG

Downstream 100 bases:

>100_bases
GCGCGCCCGCGCGCCTCGCGCGAGTCCCCGCGCGCCTCGCGCGAGTCGTCAGGCAGCGCCGAAGGGCAGGTCAAGCGAGC
CTTTCGGCGAGATGTTAAAG

Product: DNA-3-methyladenine glycosylase II

Products: NA

Alternate protein names: Regulatory protein of adaptative response; Methylated-DNA--protein-cysteine methyltransferase; O-6-methylguanine-DNA alkyltransferase [H]

Number of amino acids: Translated: 343; Mature: 342

Protein sequence:

>343_residues
MGLAAQGGAPRCRSAARGARIRRARRGRRRLSAAVESAVVPSGSVVFELPFKPPYDWPRVLRFFAGRAIPGVEAVEGGAY
RRTVDYRGAVGALTVRKHPRKRCLVATVEGDAARHADAAFAARLATMFDLHADPAAIGAHLARDAWLAPLVDAAPGLRVP
GAWSSFELIVRAIVGQQVSVKAATTIVGRLVERAGERLVGHAPGATGWRFPEPAALAACDLSRIGMPGKRAAALQGVARA
VAAGDVPLDAYATDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRP
WRAYAAMHLWNEIADRAGSARGG

Sequences:

>Translated_343_residues
MGLAAQGGAPRCRSAARGARIRRARRGRRRLSAAVESAVVPSGSVVFELPFKPPYDWPRVLRFFAGRAIPGVEAVEGGAY
RRTVDYRGAVGALTVRKHPRKRCLVATVEGDAARHADAAFAARLATMFDLHADPAAIGAHLARDAWLAPLVDAAPGLRVP
GAWSSFELIVRAIVGQQVSVKAATTIVGRLVERAGERLVGHAPGATGWRFPEPAALAACDLSRIGMPGKRAAALQGVARA
VAAGDVPLDAYATDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRP
WRAYAAMHLWNEIADRAGSARGG
>Mature_342_residues
GLAAQGGAPRCRSAARGARIRRARRGRRRLSAAVESAVVPSGSVVFELPFKPPYDWPRVLRFFAGRAIPGVEAVEGGAYR
RTVDYRGAVGALTVRKHPRKRCLVATVEGDAARHADAAFAARLATMFDLHADPAAIGAHLARDAWLAPLVDAAPGLRVPG
AWSSFELIVRAIVGQQVSVKAATTIVGRLVERAGERLVGHAPGATGWRFPEPAALAACDLSRIGMPGKRAAALQGVARAV
AAGDVPLDAYATDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVARDPALDRPASQRLRADAWRPW
RAYAAMHLWNEIADRAGSARGG

Specific function: The methylated ADA protein acts as a positive regulator of its own synthesis, as well as that of other proteins. The transcription-activating function of the ADA protein resides in its N-terminus [H]

COG id: COG0122

COG function: function code L; 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788383, Length=295, Percent_Identity=37.6271186440678, Blast_Score=154, Evalue=7e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004026
- InterPro:   IPR010316
- InterPro:   IPR011257
- InterPro:   IPR003265
- InterPro:   IPR003583
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR018060
- InterPro:   IPR023170
- InterPro:   IPR012294 [H]

Pfam domain/function: PF02805 Ada_Zn_binding; PF06029 AlkA_N; PF00730 HhH-GPD [H]

EC number: =2.1.1.63 [H]

Molecular weight: Translated: 36420; Mature: 36289

Theoretical pI: Translated: 11.51; Mature: 11.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLAAQGGAPRCRSAARGARIRRARRGRRRLSAAVESAVVPSGSVVFELPFKPPYDWPRV
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHH
LRFFAGRAIPGVEAVEGGAYRRTVDYRGAVGALTVRKHPRKRCLVATVEGDAARHADAAF
HHHHHCCCCCCCHHHCCCCEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHH
AARLATMFDLHADPAAIGAHLARDAWLAPLVDAAPGLRVPGAWSSFELIVRAIVGQQVSV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHH
KAATTIVGRLVERAGERLVGHAPGATGWRFPEPAALAACDLSRIGMPGKRAAALQGVARA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
VAAGDVPLDAYATDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVA
HHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RDPALDRPASQRLRADAWRPWRAYAAMHLWNEIADRAGSARGG
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GLAAQGGAPRCRSAARGARIRRARRGRRRLSAAVESAVVPSGSVVFELPFKPPYDWPRV
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHH
LRFFAGRAIPGVEAVEGGAYRRTVDYRGAVGALTVRKHPRKRCLVATVEGDAARHADAAF
HHHHHCCCCCCCHHHCCCCEEEEECCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHH
AARLATMFDLHADPAAIGAHLARDAWLAPLVDAAPGLRVPGAWSSFELIVRAIVGQQVSV
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCHH
KAATTIVGRLVERAGERLVGHAPGATGWRFPEPAALAACDLSRIGMPGKRAAALQGVARA
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHH
VAAGDVPLDAYATDPAGVRAALLALPGIGPWTVEYVAMRAWRDADAWPATDLVLMQAIVA
HHCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
RDPALDRPASQRLRADAWRPWRAYAAMHLWNEIADRAGSARGG
CCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]