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The map label for this gene is cobL [H]

Identifier: 83721407

GI number: 83721407

Start: 2725365

End: 2726885

Strand: Reverse

Name: cobL [H]

Synonym: BTH_I2397

Alternate gene names: 83721407

Gene position: 2726885-2725365 (Counterclockwise)

Preceding gene: 83721624

Following gene: 83720768

Centisome position: 71.59

GC content: 75.21

Gene sequence:

>1521_bases
ATGAAGGCTGGCACGAACGAAACGTCCCGGCAGGTCTCCTGGCTGGCAGGTCGTCATCCGCAGCGGGCCTTCCCGGCAGC
CGCGAAAAGGGCGGCGTGGCCAGTGGCGTGGATCGGATGCGGACTCGCTGCTCACAGTTGCGGGGGCAGCCGCAGCGGCG
CGGCGCGCCCTGCGTTCCCTCTTGGGCCCCGTGGGGCGCCGGTCGACGGACGCTGTATTATGCCTTTTTTCGCGACGCCC
GAGCGCGCAGATGCGCGATGCGGGCGTCGCTTTCAGGATCGACGGGAACACGATGGAGTACGACGGATGACCGCGTGGCT
GACGGTGGTTGGCATCGGCGACGACGGCTACGCGGGGCTCGGCCGGCCGGCGCGGCGCGCGCTCGCCGACGCGGCGGTGG
TGATGGGCGGCGAGCGGCATCTCGCGATGCTGCCCGCGCGGCACGGCGCCGAGCGCGTGCCGTGGCCGAAGCCGTTCGAT
CTCGCGCCGCTCTTCGCGCGGGCTCCGGCGCGCGTGTGCGTGCTGGCGAGCGGCGATCCGATGCTGTTCGGCGTCGGCGC
GACGCTCGCCAGCACGCTCGCGCCGAACGAGTGGCGCGTGCTGCCCGCGCCGTCGTCGCTGTCGCTCGCGGCCGCGCGCA
TCGGCTGGCCGTTGCAGGACGTCGATGCGGTGTCGCTCGTCGGCCGCCCGCTCGCGTCGCTTCACCGGCATCTGTATCCG
GGCCGGCGCCTGTTCGTGCTGAGCGCGGACGGCGCGACGCCCGCCGCGATCGCCGGCGCGCTCGCCGCGCGCGGCTTCGG
GCCGAGCGCGATGACGGTGTTCGAGCATCTCGGCGGCCCGCTCGAGCGGCGCGCCGACGCGCGCGCCGACGCGTGGGGCG
ACGCGCGTGCGGCGGCGCTGAACGTCGTCGCGATCGAATGCCGCGCGAGCGCCGATGCGCCGCGCCTGGCGCTCACGCCC
GGCTTGCCGGACGATGCGTACCGCCACGACGGCCAGCTGACGAAGCGCGATCTGCGCGCGCTCGCGCTCGGGCGGCTCGC
GCCCGCGCCGGGCGAATTGCTGTGGGACGTCGGCGCGGGCTCCGGCTCGATCGGCATCGAATGGATGCGCGCGCATCCGA
GTTGCCGGACGATCGCGATCGAAGCGCATCCGGCGCGGCAGCGCATCATCGAGCACAACCGAGATGCGCTCGGTGTGCCC
GCGCTCGAGCTCGTCGCGGGCCGCGCGCCCGAAGCGCTCGCGGGCCTGCCCGCTCCCGACGCGGTGTTCGTCGGCGGCGG
CGTGAGCCGTGAGGGCGTGCTCGACGCGTGCTGGGCCGGGCTGAAGCCGGGCGGCCGCCTCGTCGCGCACGCGGTCACGC
TGCAGGGCGAGGCGGCGCTCGTCGCATGGCGCGAGCGGCACGGCGGCGCGCTCGCGCGCGTGTCGGTCGCGCACGCGCAG
CCGCTCGGCGGCTTCGACGCGTGGCGGCAGGCGCTGCCCGTCATGCTGTACGACGCCCGCAAGCCGCAGGAGCACGAATG
A

Upstream 100 bases:

>100_bases
AACAGCGCTCCGGATCAAGCGTCGCGCGGCGGCCCGAGACGGCCGATCCCGCGCGGCAAGCGCGCGGGCGGCGGGCTACG
GCATCGGTACACCCCGCCCG

Downstream 100 bases:

>100_bases
TGCGCGACGAAACCCCCGAGCAGCCGGCGCCGCTGCGCTTCGGCTATACGACGGGCAGCTGCGCGACCGCGACGTCGCTC
GCGGCCGCGCGCCTGCTGCT

Product: precorrin-6Y C5,15-methyltransferase

Products: NA

Alternate protein names: Precorrin-6 methyltransferase; Precorrin-6Y methylase [H]

Number of amino acids: Translated: 506; Mature: 506

Protein sequence:

>506_residues
MKAGTNETSRQVSWLAGRHPQRAFPAAAKRAAWPVAWIGCGLAAHSCGGSRSGAARPAFPLGPRGAPVDGRCIMPFFATP
ERADARCGRRFQDRREHDGVRRMTAWLTVVGIGDDGYAGLGRPARRALADAAVVMGGERHLAMLPARHGAERVPWPKPFD
LAPLFARAPARVCVLASGDPMLFGVGATLASTLAPNEWRVLPAPSSLSLAAARIGWPLQDVDAVSLVGRPLASLHRHLYP
GRRLFVLSADGATPAAIAGALAARGFGPSAMTVFEHLGGPLERRADARADAWGDARAAALNVVAIECRASADAPRLALTP
GLPDDAYRHDGQLTKRDLRALALGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCRTIAIEAHPARQRIIEHNRDALGVP
ALELVAGRAPEALAGLPAPDAVFVGGGVSREGVLDACWAGLKPGGRLVAHAVTLQGEAALVAWRERHGGALARVSVAHAQ
PLGGFDAWRQALPVMLYDARKPQEHE

Sequences:

>Translated_506_residues
MKAGTNETSRQVSWLAGRHPQRAFPAAAKRAAWPVAWIGCGLAAHSCGGSRSGAARPAFPLGPRGAPVDGRCIMPFFATP
ERADARCGRRFQDRREHDGVRRMTAWLTVVGIGDDGYAGLGRPARRALADAAVVMGGERHLAMLPARHGAERVPWPKPFD
LAPLFARAPARVCVLASGDPMLFGVGATLASTLAPNEWRVLPAPSSLSLAAARIGWPLQDVDAVSLVGRPLASLHRHLYP
GRRLFVLSADGATPAAIAGALAARGFGPSAMTVFEHLGGPLERRADARADAWGDARAAALNVVAIECRASADAPRLALTP
GLPDDAYRHDGQLTKRDLRALALGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCRTIAIEAHPARQRIIEHNRDALGVP
ALELVAGRAPEALAGLPAPDAVFVGGGVSREGVLDACWAGLKPGGRLVAHAVTLQGEAALVAWRERHGGALARVSVAHAQ
PLGGFDAWRQALPVMLYDARKPQEHE
>Mature_506_residues
MKAGTNETSRQVSWLAGRHPQRAFPAAAKRAAWPVAWIGCGLAAHSCGGSRSGAARPAFPLGPRGAPVDGRCIMPFFATP
ERADARCGRRFQDRREHDGVRRMTAWLTVVGIGDDGYAGLGRPARRALADAAVVMGGERHLAMLPARHGAERVPWPKPFD
LAPLFARAPARVCVLASGDPMLFGVGATLASTLAPNEWRVLPAPSSLSLAAARIGWPLQDVDAVSLVGRPLASLHRHLYP
GRRLFVLSADGATPAAIAGALAARGFGPSAMTVFEHLGGPLERRADARADAWGDARAAALNVVAIECRASADAPRLALTP
GLPDDAYRHDGQLTKRDLRALALGRLAPAPGELLWDVGAGSGSIGIEWMRAHPSCRTIAIEAHPARQRIIEHNRDALGVP
ALELVAGRAPEALAGLPAPDAVFVGGGVSREGVLDACWAGLKPGGRLVAHAVTLQGEAALVAWRERHGGALARVSVAHAQ
PLGGFDAWRQALPVMLYDARKPQEHE

Specific function: Catalyzes the methylation of both C-5 and C-15 in precorrin-6Y to form precorrin-8X [H]

COG id: COG2242

COG function: function code H; Precorrin-6B methylase 2

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012818
- InterPro:   IPR014008
- InterPro:   IPR006365 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.132 [H]

Molecular weight: Translated: 53291; Mature: 53291

Theoretical pI: Translated: 10.45; Mature: 10.45

Prosite motif: PS00211 ABC_TRANSPORTER_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAGTNETSRQVSWLAGRHPQRAFPAAAKRAAWPVAWIGCGLAAHSCGGSRSGAARPAFP
CCCCCCCHHHHHHHHHCCCCCHHCCHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCCCC
LGPRGAPVDGRCIMPFFATPERADARCGRRFQDRREHDGVRRMTAWLTVVGIGDDGYAGL
CCCCCCCCCCEEEECEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCC
GRPARRALADAAVVMGGERHLAMLPARHGAERVPWPKPFDLAPLFARAPARVCVLASGDP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCC
MLFGVGATLASTLAPNEWRVLPAPSSLSLAAARIGWPLQDVDAVSLVGRPLASLHRHLYP
EEEECHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
GRRLFVLSADGATPAAIAGALAARGFGPSAMTVFEHLGGPLERRADARADAWGDARAAAL
CCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCHHHEEE
NVVAIECRASADAPRLALTPGLPDDAYRHDGQLTKRDLRALALGRLAPAPGELLWDVGAG
EEEEEEEECCCCCCCEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCC
SGSIGIEWMRAHPSCRTIAIEAHPARQRIIEHNRDALGVPALELVAGRAPEALAGLPAPD
CCCCCEEEEECCCCCEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHCCCCCC
AVFVGGGVSREGVLDACWAGLKPGGRLVAHAVTLQGEAALVAWRERHGGALARVSVAHAQ
EEEECCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCEEEEEEHHHCCCEEEEEEEHHCC
PLGGFDAWRQALPVMLYDARKPQEHE
CCCCHHHHHHHCCEEEEECCCCCCCC
>Mature Secondary Structure
MKAGTNETSRQVSWLAGRHPQRAFPAAAKRAAWPVAWIGCGLAAHSCGGSRSGAARPAFP
CCCCCCCHHHHHHHHHCCCCCHHCCHHHHHCCCCHHHHHCCHHHHCCCCCCCCCCCCCCC
LGPRGAPVDGRCIMPFFATPERADARCGRRFQDRREHDGVRRMTAWLTVVGIGDDGYAGL
CCCCCCCCCCEEEECEECCCCHHHHHHHHHHHHHHHHHHHHHEEEEEEEEEECCCCCCCC
GRPARRALADAAVVMGGERHLAMLPARHGAERVPWPKPFDLAPLFARAPARVCVLASGDP
CHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCC
MLFGVGATLASTLAPNEWRVLPAPSSLSLAAARIGWPLQDVDAVSLVGRPLASLHRHLYP
EEEECHHHHHHHCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCC
GRRLFVLSADGATPAAIAGALAARGFGPSAMTVFEHLGGPLERRADARADAWGDARAAAL
CCEEEEEECCCCCHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHCCCCCCCCCHHHEEE
NVVAIECRASADAPRLALTPGLPDDAYRHDGQLTKRDLRALALGRLAPAPGELLWDVGAG
EEEEEEEECCCCCCCEEECCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCCEEEEECCC
SGSIGIEWMRAHPSCRTIAIEAHPARQRIIEHNRDALGVPALELVAGRAPEALAGLPAPD
CCCCCEEEEECCCCCEEEEEECCHHHHHHHHCCCCCCCCCHHHHHHCCCCHHHHCCCCCC
AVFVGGGVSREGVLDACWAGLKPGGRLVAHAVTLQGEAALVAWRERHGGALARVSVAHAQ
EEEECCCCCCCCHHHHHHHCCCCCCEEEEEEEEECCCEEEEEEHHHCCCEEEEEEEHHCC
PLGGFDAWRQALPVMLYDARKPQEHE
CCCCHHHHHHHCCEEEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]