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The map label for this gene is putA [H]

Identifier: 83721387

GI number: 83721387

Start: 3757026

End: 3760955

Strand: Reverse

Name: putA [H]

Synonym: BTH_I3301

Alternate gene names: 83721387

Gene position: 3760955-3757026 (Counterclockwise)

Preceding gene: 83719363

Following gene: 83718998

Centisome position: 98.73

GC content: 70.31

Gene sequence:

>3930_bases
ATGGCAAGCACCACACTGGGCGTCAAAGTCGACGATCTGCTTCGCGCGCGTTTGAAGGACGCGGCGTCGCGGCTCGAGCG
CACTCCTCACTGGCTGATCAAGCAGGCGATCTTCGCGTATCTCGAGCGGATCGAGCACGGACAGCTCCCGCCGGAGCTGT
CCGGCCACACGGGCATGGCCGACCTGTCCGACGGCCACGCCGACGGCGATGAAGACGGCGCGCCGCACCCGTTCCTCGAA
TTCGCGCAGAACGTGCAGCCGCAGTCGGTGCTGCGCGCGGCGATCACGGCCGCATACCGGCGGCCGGAGCCCGAGTGCGT
GCCGTTCCTGATCGGCGAGGCGCGGCTGCCCGCGAGCCTCGCGCCGGACGTCCAGTCGATGGCGGCGGGCCTCGTCGAGG
CGCTGCGCGAGAAGAGCTCGGGCGGCGGCGTCGAGGGGCTGATCCACGAATTCTCGCTGTCGAGCCAGGAAGGCGTGGCG
CTGATGTGCCTCGCCGAGGCGCTGCTGCGGATTCCCGACCGCGCGACCCGCGACGCGCTGATCCGCGACAAGATCAGCAA
GGGCGACTGGCGCTCGCATGTCGGCCACGCGCCGTCGCTGTTCGTCAACGCGGCCACCTGGGGCCTGATGATCACGGGCA
AGCTCGTCACGACGAACAGCGAGGCGGGCCTGTCGTCGGCGCTCACGAGGCTGATCGGCAAGGGCGGCGAGCCGCTGATC
AGGAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACGGGCGAGACGATTTCCGAAGCGCTCGCGAA
CAGCCGCAAGTACGAGGCGCGCGGCTTCCGCTACTCGTACGACATGCTCGGCGAGGCGGCGACGACCGAGGAGGACGCGC
TGCGCTACTACGCTTCGTACGAGCAGGCGATCCATGCGATCGGCAAGGCGGCGGGCGGCCGCGGCATCTACGAAGGCCCG
GGTATCTCGATCAAGCTTTCGGCGCTGCACGCGCGCTACTCGCGCTCGCAGCAGGAACGCACGATGAACGAGCTGCTGCC
GCGCGTGCGCTCGCTCGCGCTGCTCGCGCGCCGCTACGACATCGGCCTGAACATCGACGCCGAGGAGGCGGACCGGCTCG
AACTGTCGCTCGATCTGCTCGAGGCGCTGTGTTTCGATTCGGAGCTCGCCGGCTGGAACGGCATCGGCTTCGTCGTGCAG
GCGTACCAGAAGCGCTGCCCGTTCGTGATCGACTACCTCGTCGATCTCGCGCGCCGCAGCCGCCATCGCCTGATGATCCG
CCTCGTGAAGGGCGCGTACTGGGATTCCGAGGTCAAGCGCGCGCAGGTGGACGGCCTCGAAGGCTATCCGGTCTACACGC
GCAAGATCTACACCGACGTGTCGTACCTCGCATGCGCGAAGAAGCTGCTCGCCGCGCCGGACGCCGTCTATCCGCAGTTC
GCGACGCACAACGCGTACACGCTCGCCGCGATCTATCACCTCGCGGGCCAGAACTATTACCCCGGCCAGTATGAATTCCA
GTGCCTGCACGGAATGGGCGAGCCGCTGTACGAGGAAGTCACCGGCCGCGACAAGCTGAACCGCCCGTGCCGCGTATACG
CGCCCGTCGGCACGCACGAGACGCTGCTCGCGTACCTCGTGCGCCGCCTGCTGGAAAACGGCGCGAACACGTCGTTCGTG
AACCGCATCGCCGACAAGACCGTGTCGGTGAAGGAGCTGGTCGCCGATCCGGTCGAGGAAGCCGCGAAGGTCGTGCCGCT
CGGCGCGCCGCACGCGAAGATTGCGCTGCCGCGCGAGCTGTACGGCGCGTCGCGCGTCAACTCGATGGGCCTCGATCTGT
CGAACGAGCACCGGCTCGCGTCGCTGTCGTCGGCGCTGCTCGCGAGCGCGCATCACCCGTGGCGCGCCGCGCCGATGCTC
GCCGACGACGCGCTCGCGCACGCCGAGCCGCGCGACGTGCGCAATCCGGCCGATCTGCGCGACGTGGTCGGCACGGTCAG
CGAGGCGACGCCCGAAGAGGTGGGCGCGGCGCTCGCGCACGCGGTCGCGGCCGCGCCGATCTGGCAGGCCACGCCGGTGG
ACGCGCGCGCCGACTGTCTCGCGCGCGCGGCGGACCTCCTCGAAGCGCAGATGCACACGCTGATGGGCCTGATCGTGCGC
GAGGCGGGCAAGTCGCTGCCGAACGCGATCGCCGAGATCCGCGAAGCGGTCGATTTCCTGCGCTACTACTCGGCGCAGAT
CCGCGACGAGTTCTCGAACGACACGCACCGCCCGCTCGGCCCCGTCGTCTGCATCAGCCCGTGGAACTTCCCGCTCGCGA
TCTTCATGGGCCAGGTGGCCGCCGCGCTTGCGGCCGGCAATACGGTGCTCGCGAAGCCGGCCGAGCAGACGCCGCTGATC
GCCGCGCAGGCGGTGCGCCTGCTGCGCGACGCCGGCGTGCCGGCGGGCGCGGTGCAACTGCTGCCCGGCAACGGCGAGAC
GGTCGGCGCGGCGCTCGTCGCCGATCCCCGCACGCGCGCGGTGATGTTCACCGGCTCGACCGAAGTCGCGCGCCTCATCA
ACAAGACGCTGTCGTCGCGCCTCGATCCGGACGGCAAGCCGATTCCGTTGATCGCCGAGACGGGCGGCCAGAACGCGATG
ATCGTCGATTCGTCGGCGCTCGCCGAGCAGGTTGTCGCCGACGTGCTGCAGTCGTCGTTCGACTCGGCCGGTCAACGCTG
TTCGGCGCTGCGCGTTCTGTGTCTGCAGGACGACGTCGCGGACCGCACGCTGACGATGCTCAAGGGCGCGATGCGCGAGC
TCGCGCTCGGCAATCCGGACCGGCTGTCGGTGGACGTCGGCCCGGTGATCGACGCCGACGCGAAGCGCACGATCGATGCG
CACATCGCGGCGATGAAGGACAAGGGGCATGCGGTCACGCAGCTCGAGATGCCGGAAGCGTGCGCGCAGGGCACGTTCGT
GCCCCCGACGATCATCGAGATCGGCAACGTCGACGAACTGAAGCGCGAGGTGTTCGGCCCGGTGCTGCACGTCGTGCGCT
ATCGCCGCAGCGGCCTCGACAAGCTGCTCGAGCAGATCCGCGCGACGGGCTACGGCCTGACGCTCGGCATCCACACGCGG
ATCGACGAGACGATCGCGCACGTGATCTCGCGCGCGCACGTCGGCAACATCTACGTGAACCGCAACGTGATCGGCGCGGT
GGTCGGCGTGCAGCCGTTCGGCGGCGAAGGGCTGTCGGGCACGGGGCCGAAGGCGGGCGGCGCGCTGTATCTGCAGCGCC
TGCTCGCGACACGCCCGGCCGGGCTGCCGCGCTCGCTCGAGGCGTCGCTCGTCGCCGATGCGCCGCAGGAAGGCGAGACG
CGCGATAATCCGTCCGCCGCGTTGACCGCGCTGCGCGACTGGCTGATCGAGCAGCGCGAGCCGGCGCTCGCCGCGCGCTG
CGACGGCTACCTGTCGCACGTGCTCGCGGGCGCAACCGCGGTGCTTTCGGGGCCGACGGGCGAGCGCAATACGTATACAC
TCGGCGCACGCGGCACGGTGCTCTGCATCGCGGCGACGGCGAGCGGCGCGCGCGCGCAGTTCGCGGCGGTGCTCGCCACG
GGCAACCGCGCGCTCTTCGCGAGCGCGGCGGGCGAGGCGCTCGCGGCGGCGCTGCCGGCGCCGCTGAAGGCGCATGCGGC
CGTGAGGAAGCAGGCGGACGCGGCGTTCGACGCGGTGCTGTTCGAGGGCGACAGCGACGAGTTGCTCGCGCTCGTGAAGG
AAGTCGCGCAGCGCCCCGGGCCGATCGTGTCGGTGCAGGGCGTCGCGGCGGGCGCGTTCGAGAACGGCGGCGACGAAGAC
TACGCGCTCGAGCGGCTCCTCACCGAGCGCTCGGTGAGCGTGAACACCGCGGCGGCAGGCGGCAATGCGAATTTGATGAC
GATTGGCTGA

Upstream 100 bases:

>100_bases
CCGGGTGCGTAATTTGGTTGCACCTTTTTATTGAGTGCCTTACGATTTTGCGATCTTTTAAAGTCCTTGGCCGGCATCGG
GCCGGCGCTAGAAGAAAATC

Downstream 100 bases:

>100_bases
GCAATCCTTGCCCTTCGATTCAAGAAACGGAAGCGGCAAGGCGAACCCGAAGTCGCTCCATTTACCCTGGTACTAGGAGA
AGATATGCAACACACGATGA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1309; Mature: 1308

Protein sequence:

>1309_residues
MASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGMADLSDGHADGDEDGAPHPFLE
FAQNVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASLAPDVQSMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDSELAGWNGIGFVVQ
AYQKRCPFVIDYLVDLARRSRHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKTVSVKELVADPVEEAAKVVPLGAPHAKIALPRELYGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
ADDALAHAEPRDVRNPADLRDVVGTVSEATPEEVGAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDA
HIAAMKDKGHAVTQLEMPEACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPRSLEASLVADAPQEGET
RDNPSAALTALRDWLIEQREPALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAVLAT
GNRALFASAAGEALAAALPAPLKAHAAVRKQADAAFDAVLFEGDSDELLALVKEVAQRPGPIVSVQGVAAGAFENGGDED
YALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1309_residues
MASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGMADLSDGHADGDEDGAPHPFLE
FAQNVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASLAPDVQSMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDSELAGWNGIGFVVQ
AYQKRCPFVIDYLVDLARRSRHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKTVSVKELVADPVEEAAKVVPLGAPHAKIALPRELYGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
ADDALAHAEPRDVRNPADLRDVVGTVSEATPEEVGAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDA
HIAAMKDKGHAVTQLEMPEACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPRSLEASLVADAPQEGET
RDNPSAALTALRDWLIEQREPALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAVLAT
GNRALFASAAGEALAAALPAPLKAHAAVRKQADAAFDAVLFEGDSDELLALVKEVAQRPGPIVSVQGVAAGAFENGGDED
YALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1308_residues
ASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGMADLSDGHADGDEDGAPHPFLEF
AQNVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASLAPDVQSMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVAL
MCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLIR
KGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASYEQAIHAIGKAAGGRGIYEGPG
ISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYDIGLNIDAEEADRLELSLDLLEALCFDSELAGWNGIGFVVQA
YQKRCPFVIDYLVDLARRSRHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQFA
THNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFVN
RIADKTVSVKELVADPVEEAAKVVPLGAPHAKIALPRELYGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLA
DDALAHAEPRDVRNPADLRDVVGTVSEATPEEVGAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVRE
AGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLIA
AQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRAVMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAMI
VDSSALAEQVVADVLQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDAH
IAAMKDKGHAVTQLEMPEACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLDKLLEQIRATGYGLTLGIHTRI
DETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPAGLPRSLEASLVADAPQEGETR
DNPSAALTALRDWLIEQREPALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAVLATG
NRALFASAAGEALAAALPAPLKAHAAVRKQADAAFDAVLFEGDSDELLALVKEVAQRPGPIVSVQGVAAGAFENGGDEDY
ALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=454, Percent_Identity=32.15859030837, Blast_Score=182, Evalue=2e-45,
Organism=Homo sapiens, GI153266822, Length=452, Percent_Identity=29.8672566371681, Blast_Score=175, Evalue=3e-43,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=30.8724832214765, Blast_Score=171, Evalue=6e-42,
Organism=Homo sapiens, GI25777730, Length=444, Percent_Identity=29.954954954955, Blast_Score=164, Evalue=6e-40,
Organism=Homo sapiens, GI25777724, Length=459, Percent_Identity=28.9760348583878, Blast_Score=164, Evalue=7e-40,
Organism=Homo sapiens, GI25777736, Length=445, Percent_Identity=30.1123595505618, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI25777734, Length=445, Percent_Identity=30.1123595505618, Blast_Score=160, Evalue=6e-39,
Organism=Homo sapiens, GI238859541, Length=447, Percent_Identity=29.9776286353468, Blast_Score=160, Evalue=8e-39,
Organism=Homo sapiens, GI25777728, Length=413, Percent_Identity=29.5399515738499, Blast_Score=157, Evalue=7e-38,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=29.0540540540541, Blast_Score=156, Evalue=1e-37,
Organism=Homo sapiens, GI21614513, Length=428, Percent_Identity=28.9719626168224, Blast_Score=155, Evalue=2e-37,
Organism=Homo sapiens, GI238814322, Length=440, Percent_Identity=27.7272727272727, Blast_Score=147, Evalue=7e-35,
Organism=Homo sapiens, GI4507229, Length=496, Percent_Identity=28.8306451612903, Blast_Score=146, Evalue=2e-34,
Organism=Homo sapiens, GI11095441, Length=426, Percent_Identity=28.8732394366197, Blast_Score=141, Evalue=4e-33,
Organism=Homo sapiens, GI25777721, Length=509, Percent_Identity=27.8978388998035, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=26.7818574514039, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=27.3318872017354, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI310128103, Length=463, Percent_Identity=26.7818574514039, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI115387104, Length=465, Percent_Identity=26.4516129032258, Blast_Score=133, Evalue=9e-31,
Organism=Homo sapiens, GI25952152, Length=438, Percent_Identity=28.0821917808219, Blast_Score=128, Evalue=3e-29,
Organism=Homo sapiens, GI310128091, Length=396, Percent_Identity=27.7777777777778, Blast_Score=120, Evalue=9e-27,
Organism=Homo sapiens, GI25777726, Length=459, Percent_Identity=25.2723311546841, Blast_Score=113, Evalue=1e-24,
Organism=Homo sapiens, GI310128087, Length=276, Percent_Identity=28.6231884057971, Blast_Score=98, Evalue=4e-20,
Organism=Homo sapiens, GI206597441, Length=440, Percent_Identity=24.5454545454545, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI206597439, Length=440, Percent_Identity=24.5454545454545, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI22907049, Length=440, Percent_Identity=24.5454545454545, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI71773324, Length=433, Percent_Identity=24.9422632794457, Blast_Score=96, Evalue=2e-19,
Organism=Homo sapiens, GI4502043, Length=390, Percent_Identity=24.8717948717949, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI238814371, Length=390, Percent_Identity=24.8717948717949, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI310128089, Length=336, Percent_Identity=26.4880952380952, Blast_Score=92, Evalue=2e-18,
Organism=Homo sapiens, GI310128095, Length=322, Percent_Identity=26.3975155279503, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI301500698, Length=432, Percent_Identity=24.537037037037, Blast_Score=83, Evalue=2e-15,
Organism=Homo sapiens, GI73695881, Length=332, Percent_Identity=24.0963855421687, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI73695879, Length=332, Percent_Identity=24.0963855421687, Blast_Score=81, Evalue=7e-15,
Organism=Homo sapiens, GI310128101, Length=223, Percent_Identity=27.8026905829596, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128099, Length=222, Percent_Identity=27.9279279279279, Blast_Score=79, Evalue=2e-14,
Organism=Homo sapiens, GI4557303, Length=336, Percent_Identity=23.2142857142857, Blast_Score=79, Evalue=4e-14,
Organism=Homo sapiens, GI73466520, Length=336, Percent_Identity=23.2142857142857, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=26.3940520446097, Blast_Score=77, Evalue=8e-14,
Organism=Escherichia coli, GI1787250, Length=1331, Percent_Identity=66.0405709992487, Blast_Score=1709, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=462, Percent_Identity=31.1688311688312, Blast_Score=183, Evalue=5e-47,
Organism=Escherichia coli, GI1787715, Length=451, Percent_Identity=32.1507760532151, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=28.695652173913, Blast_Score=157, Evalue=6e-39,
Organism=Escherichia coli, GI1788042, Length=447, Percent_Identity=31.3199105145414, Blast_Score=155, Evalue=2e-38,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=29.9270072992701, Blast_Score=143, Evalue=7e-35,
Organism=Escherichia coli, GI87081896, Length=418, Percent_Identity=28.9473684210526, Blast_Score=142, Evalue=1e-34,
Organism=Escherichia coli, GI1786504, Length=465, Percent_Identity=27.9569892473118, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI87082295, Length=466, Percent_Identity=27.6824034334764, Blast_Score=132, Evalue=2e-31,
Organism=Escherichia coli, GI87081926, Length=428, Percent_Identity=25.4672897196262, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1787653, Length=261, Percent_Identity=24.1379310344828, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=461, Percent_Identity=31.6702819956616, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25144435, Length=454, Percent_Identity=32.15859030837, Blast_Score=173, Evalue=4e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=410, Percent_Identity=32.6829268292683, Blast_Score=167, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17562198, Length=450, Percent_Identity=30.6666666666667, Blast_Score=163, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=32.2666666666667, Blast_Score=159, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI115534176, Length=470, Percent_Identity=28.0851063829787, Blast_Score=150, Evalue=3e-36,
Organism=Caenorhabditis elegans, GI25143874, Length=501, Percent_Identity=26.1477045908184, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI133930964, Length=438, Percent_Identity=27.8538812785388, Blast_Score=145, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=502, Percent_Identity=26.2948207171315, Blast_Score=144, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI32564151, Length=412, Percent_Identity=29.6116504854369, Blast_Score=143, Evalue=5e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=29.03981264637, Blast_Score=139, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17551164, Length=455, Percent_Identity=26.8131868131868, Blast_Score=130, Evalue=4e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=454, Percent_Identity=26.2114537444934, Blast_Score=122, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71995606, Length=456, Percent_Identity=26.3157894736842, Blast_Score=118, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI71995613, Length=417, Percent_Identity=25.6594724220624, Blast_Score=112, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=29.1390728476821, Blast_Score=111, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25146391, Length=412, Percent_Identity=23.7864077669903, Blast_Score=98, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=412, Percent_Identity=23.7864077669903, Blast_Score=97, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=412, Percent_Identity=23.7864077669903, Blast_Score=97, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=26.0606060606061, Blast_Score=92, Evalue=1e-18,
Organism=Saccharomyces cerevisiae, GI6320917, Length=457, Percent_Identity=32.1663019693654, Blast_Score=190, Evalue=2e-48,
Organism=Saccharomyces cerevisiae, GI6325196, Length=456, Percent_Identity=31.7982456140351, Blast_Score=175, Evalue=5e-44,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=30.0829875518672, Blast_Score=172, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6323821, Length=456, Percent_Identity=30.9210526315789, Blast_Score=165, Evalue=4e-41,
Organism=Saccharomyces cerevisiae, GI6324950, Length=413, Percent_Identity=28.8135593220339, Blast_Score=164, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=464, Percent_Identity=29.7413793103448, Blast_Score=161, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6319478, Length=460, Percent_Identity=27.8260869565217, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=536, Percent_Identity=22.5746268656716, Blast_Score=103, Evalue=1e-22,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=26.3803680981595, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281362580, Length=449, Percent_Identity=28.9532293986637, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62472918, Length=449, Percent_Identity=28.9532293986637, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62472926, Length=449, Percent_Identity=28.9532293986637, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI62472936, Length=449, Percent_Identity=28.9532293986637, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI21356737, Length=449, Percent_Identity=28.9532293986637, Blast_Score=168, Evalue=2e-41,
Organism=Drosophila melanogaster, GI20129399, Length=445, Percent_Identity=29.8876404494382, Blast_Score=163, Evalue=7e-40,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=28.5714285714286, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668425, Length=481, Percent_Identity=26.4033264033264, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668417, Length=481, Percent_Identity=26.4033264033264, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24668413, Length=481, Percent_Identity=26.4033264033264, Blast_Score=159, Evalue=1e-38,
Organism=Drosophila melanogaster, GI28574525, Length=494, Percent_Identity=27.1255060728745, Blast_Score=153, Evalue=1e-36,
Organism=Drosophila melanogaster, GI24666674, Length=452, Percent_Identity=28.7610619469027, Blast_Score=146, Evalue=1e-34,
Organism=Drosophila melanogaster, GI24585660, Length=459, Percent_Identity=26.5795206971678, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI28571802, Length=470, Percent_Identity=24.8936170212766, Blast_Score=140, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571800, Length=470, Percent_Identity=24.8936170212766, Blast_Score=140, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571806, Length=470, Percent_Identity=24.8936170212766, Blast_Score=140, Evalue=8e-33,
Organism=Drosophila melanogaster, GI28571798, Length=470, Percent_Identity=24.8936170212766, Blast_Score=140, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28571796, Length=470, Percent_Identity=24.8936170212766, Blast_Score=140, Evalue=9e-33,
Organism=Drosophila melanogaster, GI28571794, Length=470, Percent_Identity=24.8936170212766, Blast_Score=140, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24638876, Length=428, Percent_Identity=26.8691588785047, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI24638878, Length=428, Percent_Identity=26.8691588785047, Blast_Score=111, Evalue=3e-24,
Organism=Drosophila melanogaster, GI281360299, Length=335, Percent_Identity=28.6567164179104, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360297, Length=335, Percent_Identity=28.6567164179104, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360295, Length=335, Percent_Identity=28.6567164179104, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24586250, Length=335, Percent_Identity=28.6567164179104, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281360301, Length=331, Percent_Identity=28.7009063444109, Blast_Score=102, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45552499, Length=335, Percent_Identity=26.865671641791, Blast_Score=97, Evalue=1e-19,
Organism=Drosophila melanogaster, GI281360303, Length=331, Percent_Identity=26.8882175226586, Blast_Score=96, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140008; Mature: 139877

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGMA
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DLSDGHADGDEDGAPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASL
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
APDVQSMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDAL
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
IRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
HHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHH
EQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYD
HHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLELSLDLLEALCFDSELAGWNGIGFVVQAYQKRCPFVIDYLVDLARRS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHE
HCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRIADKTVSVKELVADPVEEAAKVVPLGAPHAKIALPREL
HHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCCCEECCHHH
YGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALAHAEPRDVRNPADLR
HCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHH
DVVGTVSEATPEEVGAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH
AALAAGNTVLAKPAEQTPLIAAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRA
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCCE
VMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVLQSSF
EEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHH
DSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
HIAAMKDKGHAVTQLEMPEACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLD
HHHHHHCCCCEEEEECCCHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSG
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCCC
TGPKAGGALYLQRLLATRPAGLPRSLEASLVADAPQEGETRDNPSAALTALRDWLIEQRE
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAVLAT
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHEEEC
GNRALFASAAGEALAAALPAPLKAHAAVRKQADAAFDAVLFEGDSDELLALVKEVAQRPG
CCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCC
PIVSVQGVAAGAFENGGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
CEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRARLKDAASRLERTPHWLIKQAIFAYLERIEHGQLPPELSGHTGMA
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
DLSDGHADGDEDGAPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLIGEARLPASL
CCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEEECCCCCCCCC
APDVQSMAAGLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDAL
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHHH
IRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGKGGEPLI
HHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHHH
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDALRYYASY
HHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHHH
EQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQERTMNELLPRVRSLALLARRYD
HHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
IGLNIDAEEADRLELSLDLLEALCFDSELAGWNGIGFVVQAYQKRCPFVIDYLVDLARRS
CCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHH
RHRLMIRLVKGAYWDSEVKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLAAPDAVYPQF
HHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCH
ATHNAYTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHE
HCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCHH
TLLAYLVRRLLENGANTSFVNRIADKTVSVKELVADPVEEAAKVVPLGAPHAKIALPREL
HHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHEECCCCCCCCEECCHHH
YGASRVNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALAHAEPRDVRNPADLR
HCHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCCCCCHHHH
DVVGTVSEATPEEVGAALAHAVAAAPIWQATPVDARADCLARAADLLEAQMHTLMGLIVR
HHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAGKSLPNAIAEIREAVDFLRYYSAQIRDEFSNDTHRPLGPVVCISPWNFPLAIFMGQVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHH
AALAAGNTVLAKPAEQTPLIAAQAVRLLRDAGVPAGAVQLLPGNGETVGAALVADPRTRA
HHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCEEEEEEEECCCCCE
VMFTGSTEVARLINKTLSSRLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVLQSSF
EEEECCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHHH
DSAGQRCSALRVLCLQDDVADRTLTMLKGAMRELALGNPDRLSVDVGPVIDADAKRTIDA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHH
HIAAMKDKGHAVTQLEMPEACAQGTFVPPTIIEIGNVDELKREVFGPVLHVVRYRRSGLD
HHHHHHCCCCEEEEECCCHHHHCCCCCCCHHEECCCHHHHHHHHHHHHHHHHHHHHHHHH
KLLEQIRATGYGLTLGIHTRIDETIAHVISRAHVGNIYVNRNVIGAVVGVQPFGGEGLSG
HHHHHHHHCCCEEEEEEHHHHHHHHHHHHHHHHHCEEEECCCCEEEEEECCCCCCCCCCC
TGPKAGGALYLQRLLATRPAGLPRSLEASLVADAPQEGETRDNPSAALTALRDWLIEQRE
CCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCC
PALAARCDGYLSHVLAGATAVLSGPTGERNTYTLGARGTVLCIAATASGARAQFAAVLAT
CHHHHHHHHHHHHHHHHHHHEECCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHHEEEC
GNRALFASAAGEALAAALPAPLKAHAAVRKQADAAFDAVLFEGDSDELLALVKEVAQRPG
CCCEEEEHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHEEEECCCHHHHHHHHHHHHCCC
PIVSVQGVAAGAFENGGDEDYALERLLTERSVSVNTAAAGGNANLMTIG
CEEEECCCEECCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]