Click here to switch to the map view.

The map label for this gene is coaE

Identifier: 83721162

GI number: 83721162

Start: 1279710

End: 1280321

Strand: Reverse

Name: coaE

Synonym: BTH_I1133

Alternate gene names: 83721162

Gene position: 1280321-1279710 (Counterclockwise)

Preceding gene: 83718694

Following gene: 83721262

Centisome position: 33.61

GC content: 66.34

Gene sequence:

>612_bases
ATGTTCTCGGTGGGATTGACGGGTGGGATCGGCAGCGGCAAAACGACCGTCTCCAATCTGTTCGGCGCGCTCGGTGCAAC
GATCGTCGACACCGATTTGATCGCGCACCGCATCACCGCGCCGCACGGCCTCGCGATGCCATTCATCGAGCGCGAATTCG
GCGCACAGTTCGTCGCGGCCGACGGTTCGCTCGATCGCGCAAAGATGCGCGCGCTGATCTTCAGCGACGAATCCGCGCGC
AAGCGGCTCGAAGCGATCACGCATCCGCTCATCCGCGAGGAGACCGAACGCGAGGCGGGCGCGGCGCACGGCGCGTACGT
CGTCTTCGTCGTGCCGCTGCTCGTCGAATCGGGAACGTGGGAGGCTCGCGTCGACCGCGTGCTCGTTGTCGATTGCGACG
TCGAGACGCAAATCGCGCGCGTGATGTCCCGCAACGGCTTCGCCCGCGAGCAGGTGGAAGCGATCGTCGCGCGACAGGCG
TCGCGCGACGCGCGTCTCGCCGCCGCGGACGACGTGATCGTCAACGATAATGCGTCGCTCGACGAGCTCGCAGCCGAGGT
CGCCGCACTGCACCAACGCTATCTCGGATACGCGGCAGCCGCACCAAATTGA

Upstream 100 bases:

>100_bases
CTTCGAGGAGCCGCTGCCGTTCGGCCCGTTCCTTGCGGCGGGCGGCGCCGCGACCCTCTTTTTCGGCACGCCGTTCTACC
TGCTGCTAGGAGGCTGAACC

Downstream 100 bases:

>100_bases
CGAGCTTGCTGCGTGCATGTTGCGTCCGGCGCACGAAACCGCGCGGCGCGCCGGACACCTCCGAAAAATGGCGCGATTGC
TAGGGTAGACAGTGGGCATT

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MFSVGLTGGIGSGKTTVSNLFGALGATIVDTDLIAHRITAPHGLAMPFIEREFGAQFVAADGSLDRAKMRALIFSDESAR
KRLEAITHPLIREETEREAGAAHGAYVVFVVPLLVESGTWEARVDRVLVVDCDVETQIARVMSRNGFAREQVEAIVARQA
SRDARLAAADDVIVNDNASLDELAAEVAALHQRYLGYAAAAPN

Sequences:

>Translated_203_residues
MFSVGLTGGIGSGKTTVSNLFGALGATIVDTDLIAHRITAPHGLAMPFIEREFGAQFVAADGSLDRAKMRALIFSDESAR
KRLEAITHPLIREETEREAGAAHGAYVVFVVPLLVESGTWEARVDRVLVVDCDVETQIARVMSRNGFAREQVEAIVARQA
SRDARLAAADDVIVNDNASLDELAAEVAALHQRYLGYAAAAPN
>Mature_203_residues
MFSVGLTGGIGSGKTTVSNLFGALGATIVDTDLIAHRITAPHGLAMPFIEREFGAQFVAADGSLDRAKMRALIFSDESAR
KRLEAITHPLIREETEREAGAAHGAYVVFVVPLLVESGTWEARVDRVLVVDCDVETQIARVMSRNGFAREQVEAIVARQA
SRDARLAAADDVIVNDNASLDELAAEVAALHQRYLGYAAAAPN

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain

Homologues:

Organism=Homo sapiens, GI191252797, Length=162, Percent_Identity=37.6543209876543, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI191252795, Length=162, Percent_Identity=37.6543209876543, Blast_Score=110, Evalue=1e-24,
Organism=Homo sapiens, GI110227607, Length=166, Percent_Identity=28.9156626506024, Blast_Score=72, Evalue=4e-13,
Organism=Homo sapiens, GI110227605, Length=166, Percent_Identity=28.9156626506024, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI110227603, Length=166, Percent_Identity=28.9156626506024, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI110227601, Length=166, Percent_Identity=28.9156626506024, Blast_Score=71, Evalue=6e-13,
Organism=Homo sapiens, GI205277394, Length=166, Percent_Identity=28.9156626506024, Blast_Score=71, Evalue=7e-13,
Organism=Escherichia coli, GI1786292, Length=198, Percent_Identity=46.969696969697, Blast_Score=169, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17554944, Length=192, Percent_Identity=33.8541666666667, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6320402, Length=201, Percent_Identity=32.3383084577114, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=30.5699481865285, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24658602, Length=177, Percent_Identity=28.2485875706215, Blast_Score=78, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAE_BURTA (Q2SZG8)

Other databases:

- EMBL:   CP000086
- RefSeq:   YP_441681.1
- ProteinModelPortal:   Q2SZG8
- SMR:   Q2SZG8
- STRING:   Q2SZG8
- GeneID:   3847692
- GenomeReviews:   CP000086_GR
- KEGG:   bte:BTH_I1133
- TIGR:   BTH_I1133
- eggNOG:   COG0237
- HOGENOM:   HBG650290
- OMA:   IIAREVV
- ProtClustDB:   PRK00081
- BioCyc:   BTHA271848:BTH_I1133-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00376
- InterPro:   IPR001977
- TIGRFAMs:   TIGR00152

Pfam domain/function: PF01121 CoaE

EC number: =2.7.1.24

Molecular weight: Translated: 21731; Mature: 21731

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS51219 DPCK; PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSVGLTGGIGSGKTTVSNLFGALGATIVDTDLIAHRITAPHGLAMPFIEREFGAQFVAA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEC
DGSLDRAKMRALIFSDESARKRLEAITHPLIREETEREAGAAHGAYVVFVVPLLVESGTW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
EARVDRVLVVDCDVETQIARVMSRNGFAREQVEAIVARQASRDARLAAADDVIVNDNASL
HHHHCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCH
DELAAEVAALHQRYLGYAAAAPN
HHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MFSVGLTGGIGSGKTTVSNLFGALGATIVDTDLIAHRITAPHGLAMPFIEREFGAQFVAA
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCEEEEC
DGSLDRAKMRALIFSDESARKRLEAITHPLIREETEREAGAAHGAYVVFVVPLLVESGTW
CCCCCHHHHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
EARVDRVLVVDCDVETQIARVMSRNGFAREQVEAIVARQASRDARLAAADDVIVNDNASL
HHHHCEEEEEECCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCEEECCCEEECCCCCH
DELAAEVAALHQRYLGYAAAAPN
HHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA