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The map label for this gene is lptD [H]

Identifier: 83721035

GI number: 83721035

Start: 654833

End: 657196

Strand: Direct

Name: lptD [H]

Synonym: BTH_I0575

Alternate gene names: 83721035

Gene position: 654833-657196 (Clockwise)

Preceding gene: 83721236

Following gene: 83720338

Centisome position: 17.19

GC content: 66.54

Gene sequence:

>2364_bases
ATGCCGCGTAAAACGTTACTCCCGCTCGTCCCAGCTTGCGATGCCGCGCCGCGCAGAAAACGGCTCGCGGCCGCGCTTTT
GGCCGTACCGGGCCTCGTGCCGGCGGTGTCGCAGGCCCAGTTGTCCGGCGCCGCGGCCGAGCCGCAGACGTTCGGCTCGC
CGTGGGACCTGCGCCTCGCGCCGCAGCTCGACGAGCATCCGCAAAAGCAGGGCGGCAAGCCCGCGACGTTCGTGCTCGCC
GACCACACGGGCGGCACCGCCGATCAGGACCTCGCCGCGAAGGGTTCGGCCGAGATCCGCCGCGGCAACGCGGTCGTCAA
GGCGGATGCGATCCACTACGATCAGGACACCGACATGGCCGACGCGTACGGCAAGGTCACGGTGGCCAACGGCGGCACGA
CGTTCTCGGGGCCCGAGGCGCATCTGAAGGTCGAGGCGAACCAGGGCTTCATGACGACGCCGAAGTACCATTTCACGGCG
ACGGGCGGCTCGGGCAGCGCCGAGCGCGTCCAGCTCCTCGACAGCGAACGCTCGGTGTTCACGAACGGCACGTACACGGG
CTGCCAGTGCTCGACGAACCCGGCGTGGTACATCAGGGGTAGCGAGTTCGATTTCGATACGGGCGCGGACGAGGGCGTCG
CGCGCAACGGCGTGCTGTTCTTTCAGGGCGTGCCGCTCTTCGGCAGCCCGTGGCTCACGTTTCCGCTGTCGGGCGAGCGG
CGCAGCGGCTTCCTGCCGCCGACGTTCTCGCCGTTCAGCTCGACGAACGGCATCGAGGTCTCGCTGCCGTACTATTTCAA
CATCGCGCCGAACCGCGACCTGACGATCACGCCGCACATCATTTCGAAGCGCGGGATCTTCACGCAGGCGACGTTCCGCT
ATCTGTCGACGAACTATTCGGGCGCGCTGACGGGCGAGTATCTGCCCGACGACCGCATTGCGCACCGCAACCGCTACGCG
ATCTTCTGGCAGCACCAGCAGAACTTCGGCAACGGTTTCGGCGGCTACATCTATTACAACAAGGTATCGGACAACCTGTA
TCCCGAAGAGCTCGGCTCGACGAACCAGTTCGTCAACGGGATCCAGACGGTGTATCAGCAGGAAGCCGGCCTGACCTACA
ACGACGGGCCGTGGTCGGTGCTCGGCCGTTACCAGCACTGGCAGACGCTGCCGCCGGCGGTCGCGCCGTACGGCCGCGAG
CCGCAGTTGAACGTGAAGTACGCGAAGTACAACGTCGGCGGCTTCGACTTCGGCGCGGAAGCCGATTATTCGCGCTTTAG
GATCACGACGGCCGACCAGCCGGAAGGCGACCGCGTGATGTTCAACCCGTACGTGTCGTACGGGCTGTACGGCCCCGGCT
ACTTCTTCGTGCCGAAGGCGCAGCTGCACATCGCATCGTACGACCTGACGACGACGACGGGCGGCGTGCCCGACCAGGCG
AAGCGCTTCACGTACTCGATCCCGACACTCAGCCTCGATACCGGGCTCGTGTTCGACCGCTCGGTGCGCCTGTTCGGCCA
GGACTACATCCAGACGCTGGAGCCGCGCCTGTTCTACGTGTACACGCCGTACCGGAACCAGTCGAACGCGCCGCTGTTCG
ACACGGCCGTGTCGGACTTCGGGCTCGCGGAGATCTTCACGCCGAACACGTTCGTCGGCAACGACCGGATCGCCGACGCG
AACCGTCTGACGGCCGCGCTCACGACCCGCTTCATCAATCCGGCGACGGGCGACGAGCGCGCGCGCTTCGTGATCGCGCA
GCAGTACTACTTCACCGACCAGCGCGTGACGCTCCTGCCGACCGAGGCGCCCGCGACCGCGCGGCACTCGGACCTGATCC
TCGGCGCGTCGGTCAAGCTCGGCGCGGGCTTCGCGTCGGAGACGGCGTTCCAGTACAACGTCGACAACAACCAGCTCGTG
AAGTCGAGCGTCGGCTTCGGCTACAGCCCGGGCGAGCGGCGCGTGATCAATGTCGGCTACCGCTACACGCGGCAGAATCC
GACGCTCAGCAACGAGCCGATCAACCAGATCCTCATGTCCGCGCAATGGCCGCTCACGCGGCGGCTCTACGCAGTCGGCC
GTCTCAACTACGATCTCGCGAGCAGCCGGGTTGTCGACGGTCTCGTCGGCTTCCAGTACGATGCCGACTGCTGGGCGTTC
GGCGTCGGCGTCCAGCGGTACGCGAACGGCCTGAACACGTCGGGGCAGCAGAATTCGTCGACTCGCGTGCTCGCGCAACT
CGTGCTCAAGGGTCTGACGAGCATCGACAACGGCCTCGTGACGGCGTTCCGGGCCGGCGTGCAGGGGTACACGCCGCTGC
CGCCCGCGCCGGCGCCGCTGTCGCGCTTCAGCAATTACGATTAA

Upstream 100 bases:

>100_bases
CCCGCTTCCCCCGGTATGCGCGAAGCCGCAGTCACGGTTCGATTGCGCGGGCGCGGCATGTGGAGGCCGGGCTTGACAGG
GGCGATTCGCCGAACGATAG

Downstream 100 bases:

>100_bases
CCGCCGACGAGGCGTTCGCGGCGAGCGGCGTTCGCGCAGCCCGCTTTCAATGGAGTACCTGTGGCAATGAAGAAAACCCT
TCGCTTCGCGGCTGTCGCAG

Product: organic solvent tolerance protein

Products: NA

Alternate protein names: Organic solvent tolerance protein [H]

Number of amino acids: Translated: 787; Mature: 786

Protein sequence:

>787_residues
MPRKTLLPLVPACDAAPRRKRLAAALLAVPGLVPAVSQAQLSGAAAEPQTFGSPWDLRLAPQLDEHPQKQGGKPATFVLA
DHTGGTADQDLAAKGSAEIRRGNAVVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYHFTA
TGGSGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIRGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGER
RSGFLPPTFSPFSSTNGIEVSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGALTGEYLPDDRIAHRNRYA
IFWQHQQNFGNGFGGYIYYNKVSDNLYPEELGSTNQFVNGIQTVYQQEAGLTYNDGPWSVLGRYQHWQTLPPAVAPYGRE
PQLNVKYAKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHIASYDLTTTTGGVPDQA
KRFTYSIPTLSLDTGLVFDRSVRLFGQDYIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADA
NRLTAALTTRFINPATGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLV
KSSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
GVGVQRYANGLNTSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD

Sequences:

>Translated_787_residues
MPRKTLLPLVPACDAAPRRKRLAAALLAVPGLVPAVSQAQLSGAAAEPQTFGSPWDLRLAPQLDEHPQKQGGKPATFVLA
DHTGGTADQDLAAKGSAEIRRGNAVVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYHFTA
TGGSGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIRGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGER
RSGFLPPTFSPFSSTNGIEVSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGALTGEYLPDDRIAHRNRYA
IFWQHQQNFGNGFGGYIYYNKVSDNLYPEELGSTNQFVNGIQTVYQQEAGLTYNDGPWSVLGRYQHWQTLPPAVAPYGRE
PQLNVKYAKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHIASYDLTTTTGGVPDQA
KRFTYSIPTLSLDTGLVFDRSVRLFGQDYIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADA
NRLTAALTTRFINPATGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLV
KSSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
GVGVQRYANGLNTSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD
>Mature_786_residues
PRKTLLPLVPACDAAPRRKRLAAALLAVPGLVPAVSQAQLSGAAAEPQTFGSPWDLRLAPQLDEHPQKQGGKPATFVLAD
HTGGTADQDLAAKGSAEIRRGNAVVKADAIHYDQDTDMADAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYHFTAT
GGSGSAERVQLLDSERSVFTNGTYTGCQCSTNPAWYIRGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGERR
SGFLPPTFSPFSSTNGIEVSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYSGALTGEYLPDDRIAHRNRYAI
FWQHQQNFGNGFGGYIYYNKVSDNLYPEELGSTNQFVNGIQTVYQQEAGLTYNDGPWSVLGRYQHWQTLPPAVAPYGREP
QLNVKYAKYNVGGFDFGAEADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHIASYDLTTTTGGVPDQAK
RFTYSIPTLSLDTGLVFDRSVRLFGQDYIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDFGLAEIFTPNTFVGNDRIADAN
RLTAALTTRFINPATGDERARFVIAQQYYFTDQRVTLLPTEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVK
SSVGFGYSPGERRVINVGYRYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAFG
VGVQRYANGLNTSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPLSRFSNYD

Specific function: Involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis [H]

COG id: COG1452

COG function: function code M; Organic solvent tolerance protein OstA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptD family [H]

Homologues:

Organism=Escherichia coli, GI1786239, Length=773, Percent_Identity=27.4256144890039, Blast_Score=260, Evalue=3e-70,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020889
- InterPro:   IPR007543 [H]

Pfam domain/function: PF04453 OstA_C [H]

EC number: NA

Molecular weight: Translated: 86451; Mature: 86320

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKTLLPLVPACDAAPRRKRLAAALLAVPGLVPAVSQAQLSGAAAEPQTFGSPWDLRLA
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEC
PQLDEHPQKQGGKPATFVLADHTGGTADQDLAAKGSAEIRRGNAVVKADAIHYDQDTDMA
CCCCCCHHHCCCCCEEEEEEECCCCCCCCHHHCCCCCEEECCCEEEEEEEEECCCCCCHH
DAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYHFTATGGSGSAERVQLLDSERSVF
HCCCEEEEECCCCCCCCCCEEEEEECCCCEEECCCEEEEEECCCCCHHHEEEECCCCCEE
TNGTYTGCQCSTNPAWYIRGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGER
ECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCC
RSGFLPPTFSPFSSTNGIEVSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYS
CCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEECCHHHCCCCCCHHHHHHHHHCCCC
GALTGEYLPDDRIAHRNRYAIFWQHQQNFGNGFGGYIYYNKVSDNLYPEELGSTNQFVNG
CEEECCCCCCCHHCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHCCCHHHHHHH
IQTVYQQEAGLTYNDGPWSVLGRYQHWQTLPPAVAPYGREPQLNVKYAKYNVGGFDFGAE
HHHHHHHHCCCEECCCCHHHHCCCHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
ADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHIASYDLTTTTGGVPDQA
CCCCEEEEEECCCCCCCEEEECCEEECCCCCCCEEEECCCEEEEEEEEEECCCCCCCCHH
KRFTYSIPTLSLDTGLVFDRSVRLFGQDYIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDF
CEEEEECCEEECCCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCC
GLAEIFTPNTFVGNDRIADANRLTAALTTRFINPATGDERARFVIAQQYYFTDQRVTLLP
CCEEEECCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCEEEEEE
TEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVKSSVGFGYSPGERRVINVGY
CCCCCCCCCCCEEEECCEEECCCCCCCCEEEEECCCCEEEHHCCCCCCCCCCCEEEEECE
RYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
EEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEE
GVGVQRYANGLNTSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPL
CCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCH
SRFSNYD
HHCCCCC
>Mature Secondary Structure 
PRKTLLPLVPACDAAPRRKRLAAALLAVPGLVPAVSQAQLSGAAAEPQTFGSPWDLRLA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCCCCCCCEEEC
PQLDEHPQKQGGKPATFVLADHTGGTADQDLAAKGSAEIRRGNAVVKADAIHYDQDTDMA
CCCCCCHHHCCCCCEEEEEEECCCCCCCCHHHCCCCCEEECCCEEEEEEEEECCCCCCHH
DAYGKVTVANGGTTFSGPEAHLKVEANQGFMTTPKYHFTATGGSGSAERVQLLDSERSVF
HCCCEEEEECCCCCCCCCCEEEEEECCCCEEECCCEEEEEECCCCCHHHEEEECCCCCEE
TNGTYTGCQCSTNPAWYIRGSEFDFDTGADEGVARNGVLFFQGVPLFGSPWLTFPLSGER
ECCCCCCEEECCCCEEEEECCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCEEEECCCCC
RSGFLPPTFSPFSSTNGIEVSLPYYFNIAPNRDLTITPHIISKRGIFTQATFRYLSTNYS
CCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCEEECCHHHCCCCCCHHHHHHHHHCCCC
GALTGEYLPDDRIAHRNRYAIFWQHQQNFGNGFGGYIYYNKVSDNLYPEELGSTNQFVNG
CEEECCCCCCCHHCCCCEEEEEEEECCCCCCCCCCEEEEEECCCCCCHHHCCCHHHHHHH
IQTVYQQEAGLTYNDGPWSVLGRYQHWQTLPPAVAPYGREPQLNVKYAKYNVGGFDFGAE
HHHHHHHHCCCEECCCCHHHHCCCHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCCCCCC
ADYSRFRITTADQPEGDRVMFNPYVSYGLYGPGYFFVPKAQLHIASYDLTTTTGGVPDQA
CCCCEEEEEECCCCCCCEEEECCEEECCCCCCCEEEECCCEEEEEEEEEECCCCCCCCHH
KRFTYSIPTLSLDTGLVFDRSVRLFGQDYIQTLEPRLFYVYTPYRNQSNAPLFDTAVSDF
CEEEEECCEEECCCCEEEECHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHHHCCC
GLAEIFTPNTFVGNDRIADANRLTAALTTRFINPATGDERARFVIAQQYYFTDQRVTLLP
CCEEEECCCEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEEEEEEECCCEEEEEE
TEAPATARHSDLILGASVKLGAGFASETAFQYNVDNNQLVKSSVGFGYSPGERRVINVGY
CCCCCCCCCCCEEEECCEEECCCCCCCCEEEEECCCCEEEHHCCCCCCCCCCCEEEEECE
RYTRQNPTLSNEPINQILMSAQWPLTRRLYAVGRLNYDLASSRVVDGLVGFQYDADCWAF
EEECCCCCCCCCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCEECCCCEEE
GVGVQRYANGLNTSGQQNSSTRVLAQLVLKGLTSIDNGLVTAFRAGVQGYTPLPPAPAPL
CCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCH
SRFSNYD
HHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA