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The map label for this gene is surA [H]

Identifier: 83720338

GI number: 83720338

Start: 657263

End: 658609

Strand: Direct

Name: surA [H]

Synonym: BTH_I0576

Alternate gene names: 83720338

Gene position: 657263-658609 (Clockwise)

Preceding gene: 83721035

Following gene: 83719957

Centisome position: 17.25

GC content: 68.52

Gene sequence:

>1347_bases
ATGAAGAAAACCCTTCGCTTCGCGGCTGTCGCAGCCGGTCTGGTCGCGTCGCTCATCACGGTCGCGCCGTCGGCGTCCGC
GCAGGCGCTGCGCGCGCAGGGCGCGTCGCTCGCCGACGAGGTGGTCGCCGTCGTCAACAACGACGTGATCACGGGGCGCG
AGCTCGATCAGCGCGTCGGCCTGATCGCGCGCCGCCTGCAGCAGCAGAAGGCGCCCGTGCCGCCGACGGACCAGTTGCGC
GCACAGGTGCTGAACCAGATGGTGCTAGAGCGCATCCAGGTCCAGCGGGCGAAGGACGATGGCATCGTCGTCGACAACGC
AACCGTGCAGGCGACGCTCGGCCGCCTCGCGCAAGCGAACGGGATGCCGCTCGACCAGTACAAGGCGCGCATCGAGGCCC
AGGGCGTGCCGTGGGATCTGTTCGTGCGCGACGCGCGCACCGAGCTGATGCTCTCGAAGCTGCGCGAGAAGGAGGTCGAC
AGCAAGATCACGGTGTCGGACGCCGAGGTCGCGAGCTACATCGCGAGCCAGCGCGGCCCGAATGCGGGCGCGCAGCAGGA
TCTGCGGCTCGAGCACATCTTCGTGAAGGCGCCGACCAACGCGCCGCAGGCCGATATCGACGCCGCGCAGAAGAAGGCCG
AAGGCCTGCTGCAGCAGGCGCTCGCGTCGGGGACCAATTTCGAGCGCCTTGCGAAGAGTCAATCGGAAGCCGACGACGCG
AAGAAGGGCGGCGACCTCGGCTTCAAGGCGCCGTCGTCGCTGCCTTCCGACGTCGTCGACGCCGTGTCGAAGCTGCGTCC
CGGCGAGGTCAACCCGACGCTGATCCGCGTGCCGGACGGCTTCGAGATCGTGCGTCTCGTCGACCGCCGCGCGAGCCAGA
ATCCGGCCGCGTCGCCGAAGATCGTGCAGACGCACGTGCGCCACATCCTGCTGCGCGTCGGCGAAGGCAAGTCGGAATCA
CAGGCGCGTCAGCAACTGATCGACATTCGCCGGCAGATCGAGGCGGGCGGCGATTTCGAGAAATTCGCGCGCACCTACTC
GCAGGACGGCTCGGCGTCGCAAGGCGGCGATCTCGGCTGGATCAGCCCGGGCGAGACGGTGCCCGAATTCGAGCGTGCGA
TGAACGCGCTGCAGGACGGCCAGGTCAGCAACCCGGTGCGCACGGAGTACGGCTACCACCTGATCCAGGTGCTCGGCCGC
CGCGACGCGGAAGGCTCGGTGCAGCAGCAGATGGACATCGCGCGCCAGGCGATCGGCCAGCGCAAGGCCGAGCAGGCGTA
TTCCGACTGGCTGCGCGAGCTGCGCGACTCGTCGTACGTGCAGATCAAGCTGCCCGTCGGCCAGTAA

Upstream 100 bases:

>100_bases
GGCGCCGCTGTCGCGCTTCAGCAATTACGATTAACCGCCGACGAGGCGTTCGCGGCGAGCGGCGTTCGCGCAGCCCGCTT
TCAATGGAGTACCTGTGGCA

Downstream 100 bases:

>100_bases
GCACAAGCCCATAGGCGCATTCATGTCCGCCCGTCCGCAGCCGCTGCGCATCGCGATCACGACCGGCGAGCCGGCCGGCG
TCGGCCCCGAGCTGACGGCG

Product: survival protein SurA

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 448; Mature: 448

Protein sequence:

>448_residues
MKKTLRFAAVAAGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVGLIARRLQQQKAPVPPTDQLR
AQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQANGMPLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVD
SKITVSDAEVASYIASQRGPNAGAQQDLRLEHIFVKAPTNAPQADIDAAQKKAEGLLQQALASGTNFERLAKSQSEADDA
KKGGDLGFKAPSSLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVDRRASQNPAASPKIVQTHVRHILLRVGEGKSES
QARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQVSNPVRTEYGYHLIQVLGR
RDAEGSVQQQMDIARQAIGQRKAEQAYSDWLRELRDSSYVQIKLPVGQ

Sequences:

>Translated_448_residues
MKKTLRFAAVAAGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVGLIARRLQQQKAPVPPTDQLR
AQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQANGMPLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVD
SKITVSDAEVASYIASQRGPNAGAQQDLRLEHIFVKAPTNAPQADIDAAQKKAEGLLQQALASGTNFERLAKSQSEADDA
KKGGDLGFKAPSSLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVDRRASQNPAASPKIVQTHVRHILLRVGEGKSES
QARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQVSNPVRTEYGYHLIQVLGR
RDAEGSVQQQMDIARQAIGQRKAEQAYSDWLRELRDSSYVQIKLPVGQ
>Mature_448_residues
MKKTLRFAAVAAGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVGLIARRLQQQKAPVPPTDQLR
AQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQANGMPLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVD
SKITVSDAEVASYIASQRGPNAGAQQDLRLEHIFVKAPTNAPQADIDAAQKKAEGLLQQALASGTNFERLAKSQSEADDA
KKGGDLGFKAPSSLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVDRRASQNPAASPKIVQTHVRHILLRVGEGKSES
QARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNALQDGQVSNPVRTEYGYHLIQVLGR
RDAEGSVQQQMDIARQAIGQRKAEQAYSDWLRELRDSSYVQIKLPVGQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=391, Percent_Identity=32.2250639386189, Blast_Score=194, Evalue=1e-50,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48800; Mature: 48800

Theoretical pI: Translated: 8.72; Mature: 8.72

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLRFAAVAAGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVG
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
LIARRLQQQKAPVPPTDQLRAQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQAN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCC
GMPLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVDSKITVSDAEVASYIASQRGP
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCC
NAGAQQDLRLEHIFVKAPTNAPQADIDAAQKKAEGLLQQALASGTNFERLAKSQSEADDA
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KKGGDLGFKAPSSLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVDRRASQNPAASPK
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHH
IVQTHVRHILLRVGEGKSESQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
ISPGETVPEFERAMNALQDGQVSNPVRTEYGYHLIQVLGRRDAEGSVQQQMDIARQAIGQ
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RKAEQAYSDWLRELRDSSYVQIKLPVGQ
HHHHHHHHHHHHHHCCCCEEEEEECCCC
>Mature Secondary Structure
MKKTLRFAAVAAGLVASLITVAPSASAQALRAQGASLADEVVAVVNNDVITGRELDQRVG
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHH
LIARRLQQQKAPVPPTDQLRAQVLNQMVLERIQVQRAKDDGIVVDNATVQATLGRLAQAN
HHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHHHHHHCC
GMPLDQYKARIEAQGVPWDLFVRDARTELMLSKLREKEVDSKITVSDAEVASYIASQRGP
CCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHCCC
NAGAQQDLRLEHIFVKAPTNAPQADIDAAQKKAEGLLQQALASGTNFERLAKSQSEADDA
CCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
KKGGDLGFKAPSSLPSDVVDAVSKLRPGEVNPTLIRVPDGFEIVRLVDRRASQNPAASPK
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHH
IVQTHVRHILLRVGEGKSESQARQQLIDIRRQIEAGGDFEKFARTYSQDGSASQGGDLGW
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCCCCCCCCC
ISPGETVPEFERAMNALQDGQVSNPVRTEYGYHLIQVLGRRDAEGSVQQQMDIARQAIGQ
CCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RKAEQAYSDWLRELRDSSYVQIKLPVGQ
HHHHHHHHHHHHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA