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The map label for this gene is phoA [H]

Identifier: 83720832

GI number: 83720832

Start: 368389

End: 370062

Strand: Direct

Name: phoA [H]

Synonym: BTH_I0332

Alternate gene names: 83720832

Gene position: 368389-370062 (Clockwise)

Preceding gene: 83720592

Following gene: 83721540

Centisome position: 9.67

GC content: 68.22

Gene sequence:

>1674_bases
GTGGCCCAAGGCCGGCGCAGCCGCACCGACGCGGGCCGCCCCGCTTGCCGCCCCGGCCCCCCCGGCAACGGCCGGTCGCG
ACCGGAAGCCGTCCGCCGGCGGCATCCGTCTGCCGCGCGAAACCATTCGATTTCCATTCTTCAGTCTTTCAATTTCATTC
ATATTCGCGTCATATCGCCCCCGTATCGTCCTCGCGTTTCTGAAAGAAATCACACCAACGGGAAGCCGAAAAACATGAAG
CGAGTGAGACTGGCCGCGCTCCTTTGCGCGAGCGTCTTCGCGGCGGCGGGCTGCGGCAGCGACGAGCCGAAGACGCCGGG
CGCATCGGACGACGGCGCGCGAACGAGCGCCGCGCGCAACGTCATCTTCTTTCTGGGCGACGGGATGGGGATGACGACGC
TCACGGCCGCGCGGATCTATGTGGTCGGCGAGGACGGCGCGCTCACGCTCGACACGCTGCCCGAGACCGCGTTCGTGAAG
ACCTATTCGAACGATGCGCAGGTGACGGACAGCGCGCCGTCGATGTCCGCGTACATGACGGGCGTGAAGACGAACAACGA
AGTGATCTCGATGACGCCCGACACGAAGGCGATCGAGCCGAGCGCGAGTCTCACCGGCAACTGCGGCGCGAACAACGGCA
AGCCGGTGCCGACGCTGCTCGAGATCGCGAAGGCGAAGGGGCTCGCGACGGGCGTCGTCACGACGACCCGCGTCACGCAC
GCGACGCCCGCCGCGACCTACGCGCACGTGTGCCACCGCGACGCCGAGAACGACATCGCCGCGCAGCTCGTGCCGGGCGG
CGCGGGCTACAACGCAGCGCTCGGCGGCGGCGTCGACGTCGTGCTGGGCGGCGGCGCGCAGTTCTTCGTGCCGAAGGACG
CCGGCGGCAAGCGCGCGGACGGCCGCAATCTCGTGAACGAGCTGAAGGCGAAGGGCTATGCGATCGCGCAGAACCGCGAC
GAGCTCCTCGCCGCCGATGCGACGAAGAGCGGCAAGCTCGCGGGCCTGTTCGCATCGAGCCACATGAGCTACGACCTCGA
CCGCGGCGCGACGAAGGAGCCGAGCCTGGCGGACATGGCGACGCGCGCGCTCGACGTGTTGCAGAAGAACCCGAACGGCT
ATTTCCTGATGGTCGAAGGCGGGCGGATCGATCACGCGCTGCACGACACGAACGCGAAGCGTGCGCTGCAGGACACGGTT
GCGTTCGACAACGCGATCAAGGCGACGCTCGACAAGGTCCGTCAGACCGATCCGGACCTGAAGAACACGTTGATCGTCGT
GACGGCCGACCACGACCACACGCTGGTGCTCAACGGTTACGCGGCGCGCACGGGCAAGACGGAAGCGGGCAAGCCGGGCG
TGCTCGGCGTGCTGCGCAACTATCAGACGGGTGCGGTCGCGAAGGACGCGGACGGCGCGCCGTACACGATCATCGGCTTC
GGCAACGGCGAGAACCGCGTGCAAGGCAGCCGCGCGGGCACGAACCTTACCGACGCGGTGACGGGCGCGGACGACTATCG
CCAGGAGGCGGTCGTGCGAATGGCGAAGGGCAGCGAGACGCACGGCGGCACCGACGTGTTCCTCGGCGCGATCGGCCGCG
GCGCGGAGGGCTTTCACGGCGTGATCGAGAACAACAAGGTGTTCGAGCTCGTGCGCGGCGCGGCGCAGCTCTGA

Upstream 100 bases:

>100_bases
TCAGGCGCGCGGCATGATGAACGCGCGGCGCCATCGCGGGTTCGTCGCCGGCGGCTGATCCGGCGCTCGTTCGCCGGGAA
TCACTCGCGGCGGGGCATGC

Downstream 100 bases:

>100_bases
GCGCGGCCTCGACGGAACAGGGGAATACAGGATGTCGACTATCAAGCGCATCGCGGCGGCGTTCGCCGCGGCGGCCCTTT
CGGGCGGTGTCGGCCAGGCG

Product: alkaline phosphatase family protein

Products: NA

Alternate protein names: APase [H]

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MAQGRRSRTDAGRPACRPGPPGNGRSRPEAVRRRHPSAARNHSISILQSFNFIHIRVISPPYRPRVSERNHTNGKPKNMK
RVRLAALLCASVFAAAGCGSDEPKTPGASDDGARTSAARNVIFFLGDGMGMTTLTAARIYVVGEDGALTLDTLPETAFVK
TYSNDAQVTDSAPSMSAYMTGVKTNNEVISMTPDTKAIEPSASLTGNCGANNGKPVPTLLEIAKAKGLATGVVTTTRVTH
ATPAATYAHVCHRDAENDIAAQLVPGGAGYNAALGGGVDVVLGGGAQFFVPKDAGGKRADGRNLVNELKAKGYAIAQNRD
ELLAADATKSGKLAGLFASSHMSYDLDRGATKEPSLADMATRALDVLQKNPNGYFLMVEGGRIDHALHDTNAKRALQDTV
AFDNAIKATLDKVRQTDPDLKNTLIVVTADHDHTLVLNGYAARTGKTEAGKPGVLGVLRNYQTGAVAKDADGAPYTIIGF
GNGENRVQGSRAGTNLTDAVTGADDYRQEAVVRMAKGSETHGGTDVFLGAIGRGAEGFHGVIENNKVFELVRGAAQL

Sequences:

>Translated_557_residues
MAQGRRSRTDAGRPACRPGPPGNGRSRPEAVRRRHPSAARNHSISILQSFNFIHIRVISPPYRPRVSERNHTNGKPKNMK
RVRLAALLCASVFAAAGCGSDEPKTPGASDDGARTSAARNVIFFLGDGMGMTTLTAARIYVVGEDGALTLDTLPETAFVK
TYSNDAQVTDSAPSMSAYMTGVKTNNEVISMTPDTKAIEPSASLTGNCGANNGKPVPTLLEIAKAKGLATGVVTTTRVTH
ATPAATYAHVCHRDAENDIAAQLVPGGAGYNAALGGGVDVVLGGGAQFFVPKDAGGKRADGRNLVNELKAKGYAIAQNRD
ELLAADATKSGKLAGLFASSHMSYDLDRGATKEPSLADMATRALDVLQKNPNGYFLMVEGGRIDHALHDTNAKRALQDTV
AFDNAIKATLDKVRQTDPDLKNTLIVVTADHDHTLVLNGYAARTGKTEAGKPGVLGVLRNYQTGAVAKDADGAPYTIIGF
GNGENRVQGSRAGTNLTDAVTGADDYRQEAVVRMAKGSETHGGTDVFLGAIGRGAEGFHGVIENNKVFELVRGAAQL
>Mature_556_residues
AQGRRSRTDAGRPACRPGPPGNGRSRPEAVRRRHPSAARNHSISILQSFNFIHIRVISPPYRPRVSERNHTNGKPKNMKR
VRLAALLCASVFAAAGCGSDEPKTPGASDDGARTSAARNVIFFLGDGMGMTTLTAARIYVVGEDGALTLDTLPETAFVKT
YSNDAQVTDSAPSMSAYMTGVKTNNEVISMTPDTKAIEPSASLTGNCGANNGKPVPTLLEIAKAKGLATGVVTTTRVTHA
TPAATYAHVCHRDAENDIAAQLVPGGAGYNAALGGGVDVVLGGGAQFFVPKDAGGKRADGRNLVNELKAKGYAIAQNRDE
LLAADATKSGKLAGLFASSHMSYDLDRGATKEPSLADMATRALDVLQKNPNGYFLMVEGGRIDHALHDTNAKRALQDTVA
FDNAIKATLDKVRQTDPDLKNTLIVVTADHDHTLVLNGYAARTGKTEAGKPGVLGVLRNYQTGAVAKDADGAPYTIIGFG
NGENRVQGSRAGTNLTDAVTGADDYRQEAVVRMAKGSETHGGTDVFLGAIGRGAEGFHGVIENNKVFELVRGAAQL

Specific function: Unknown

COG id: COG1785

COG function: function code P; Alkaline phosphatase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alkaline phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI157266296, Length=476, Percent_Identity=36.9747899159664, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI94721246, Length=476, Percent_Identity=36.9747899159664, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI116734717, Length=471, Percent_Identity=36.3057324840764, Blast_Score=251, Evalue=1e-66,
Organism=Homo sapiens, GI157266292, Length=474, Percent_Identity=37.1308016877637, Blast_Score=249, Evalue=7e-66,
Organism=Homo sapiens, GI294660770, Length=463, Percent_Identity=35.85313174946, Blast_Score=241, Evalue=2e-63,
Organism=Homo sapiens, GI294660772, Length=429, Percent_Identity=34.4988344988345, Blast_Score=210, Evalue=2e-54,
Organism=Escherichia coli, GI48994877, Length=424, Percent_Identity=32.311320754717, Blast_Score=149, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6320689, Length=339, Percent_Identity=33.6283185840708, Blast_Score=153, Evalue=7e-38,
Organism=Drosophila melanogaster, GI21355151, Length=470, Percent_Identity=37.6595744680851, Blast_Score=255, Evalue=6e-68,
Organism=Drosophila melanogaster, GI85725200, Length=459, Percent_Identity=36.6013071895425, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI85815833, Length=459, Percent_Identity=36.6013071895425, Blast_Score=251, Evalue=8e-67,
Organism=Drosophila melanogaster, GI24585213, Length=469, Percent_Identity=35.8208955223881, Blast_Score=235, Evalue=5e-62,
Organism=Drosophila melanogaster, GI21355981, Length=458, Percent_Identity=35.1528384279476, Blast_Score=232, Evalue=4e-61,
Organism=Drosophila melanogaster, GI21358067, Length=480, Percent_Identity=35.8333333333333, Blast_Score=231, Evalue=1e-60,
Organism=Drosophila melanogaster, GI24651554, Length=479, Percent_Identity=36.9519832985386, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI18859923, Length=462, Percent_Identity=36.7965367965368, Blast_Score=222, Evalue=6e-58,
Organism=Drosophila melanogaster, GI19921912, Length=485, Percent_Identity=34.2268041237113, Blast_Score=219, Evalue=3e-57,
Organism=Drosophila melanogaster, GI21355149, Length=475, Percent_Identity=32.8421052631579, Blast_Score=214, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24657827, Length=475, Percent_Identity=34.1052631578947, Blast_Score=206, Evalue=4e-53,
Organism=Drosophila melanogaster, GI24651556, Length=468, Percent_Identity=36.1111111111111, Blast_Score=205, Evalue=8e-53,
Organism=Drosophila melanogaster, GI24657835, Length=470, Percent_Identity=32.7659574468085, Blast_Score=195, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24657842, Length=473, Percent_Identity=31.5010570824524, Blast_Score=192, Evalue=6e-49,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR001952
- InterPro:   IPR018299
- InterPro:   IPR017850 [H]

Pfam domain/function: PF00245 Alk_phosphatase [H]

EC number: =3.1.3.1 [H]

Molecular weight: Translated: 58425; Mature: 58294

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQGRRSRTDAGRPACRPGPPGNGRSRPEAVRRRHPSAARNHSISILQSFNFIHIRVISP
CCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCEEEEECCCEEEEEEECC
PYRPRVSERNHTNGKPKNMKRVRLAALLCASVFAAAGCGSDEPKTPGASDDGARTSAARN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCE
VIFFLGDGMGMTTLTAARIYVVGEDGALTLDTLPETAFVKTYSNDAQVTDSAPSMSAYMT
EEEEEECCCCCCEEEEEEEEEEECCCEEEECCCCCEEEEEEECCCCEECCCCCCCCHHEE
GVKTNNEVISMTPDTKAIEPSASLTGNCGANNGKPVPTLLEIAKAKGLATGVVTTTRVTH
ECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEECEEEEEEEEC
ATPAATYAHVCHRDAENDIAAQLVPGGAGYNAALGGGVDVVLGGGAQFFVPKDAGGKRAD
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC
GRNLVNELKAKGYAIAQNRDELLAADATKSGKLAGLFASSHMSYDLDRGATKEPSLADMA
HHHHHHHHHHCCEEEECCCCCEEEECCCCCCCEEEEEECCCCCEECCCCCCCCCCHHHHH
TRALDVLQKNPNGYFLMVEGGRIDHALHDTNAKRALQDTVAFDNAIKATLDKVRQTDPDL
HHHHHHHHCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KNTLIVVTADHDHTLVLNGYAARTGKTEAGKPGVLGVLRNYQTGAVAKDADGAPYTIIGF
HCEEEEEEECCCCEEEEECEECCCCCCCCCCCCHHHHHHCCCCCCCEECCCCCCEEEEEE
GNGENRVQGSRAGTNLTDAVTGADDYRQEAVVRMAKGSETHGGTDVFLGAIGRGAEGFHG
CCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCH
VIENNKVFELVRGAAQL
HHCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AQGRRSRTDAGRPACRPGPPGNGRSRPEAVRRRHPSAARNHSISILQSFNFIHIRVISP
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHCCCEEEEECCCEEEEEEECC
PYRPRVSERNHTNGKPKNMKRVRLAALLCASVFAAAGCGSDEPKTPGASDDGARTSAARN
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCE
VIFFLGDGMGMTTLTAARIYVVGEDGALTLDTLPETAFVKTYSNDAQVTDSAPSMSAYMT
EEEEEECCCCCCEEEEEEEEEEECCCEEEECCCCCEEEEEEECCCCEECCCCCCCCHHEE
GVKTNNEVISMTPDTKAIEPSASLTGNCGANNGKPVPTLLEIAKAKGLATGVVTTTRVTH
ECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCEECEEEEEEEEC
ATPAATYAHVCHRDAENDIAAQLVPGGAGYNAALGGGVDVVLGGGAQFFVPKDAGGKRAD
CCCHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCCCC
GRNLVNELKAKGYAIAQNRDELLAADATKSGKLAGLFASSHMSYDLDRGATKEPSLADMA
HHHHHHHHHHCCEEEECCCCCEEEECCCCCCCEEEEEECCCCCEECCCCCCCCCCHHHHH
TRALDVLQKNPNGYFLMVEGGRIDHALHDTNAKRALQDTVAFDNAIKATLDKVRQTDPDL
HHHHHHHHCCCCCEEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
KNTLIVVTADHDHTLVLNGYAARTGKTEAGKPGVLGVLRNYQTGAVAKDADGAPYTIIGF
HCEEEEEEECCCCEEEEECEECCCCCCCCCCCCHHHHHHCCCCCCCEECCCCCCEEEEEE
GNGENRVQGSRAGTNLTDAVTGADDYRQEAVVRMAKGSETHGGTDVFLGAIGRGAEGFHG
CCCCCCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCH
VIENNKVFELVRGAAQL
HHCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2129542 [H]