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The map label for this gene is sir1 [H]

Identifier: 83720632

GI number: 83720632

Start: 928230

End: 929999

Strand: Direct

Name: sir1 [H]

Synonym: BTH_I0814

Alternate gene names: 83720632

Gene position: 928230-929999 (Clockwise)

Preceding gene: 83719248

Following gene: 83721577

Centisome position: 24.37

GC content: 66.38

Gene sequence:

>1770_bases
ATGGCCGACTCGGCGCGGACGGTGCAGGATTCGGGCGCGGCGTGGCTAGGACGCCGCGCGGTCATATCGAGCAAACCCTG
GGGTCCCCGAATGTACCAGTACGACCAGTACGATCAGACGATCGTCGACGAGCGCGTCGCGCAGTACCGCGACCAGGTCC
GCCGCCGCTTGTCCGGCGAATTGAGCGAGGACGAGTTCCGTCCGTTGCGGCTGCAGAACGGCCTGTACATGCAGCGCCAC
GCGTACATGCACCGCATCGCGATTCCCTACGGCAATCTCCGCAGCGTCCAGTTGCGCATGCTCGCACGCATCGCGCGCGA
GCACGATCGCGGCTACGGCCACTTCTCGACGCGCTCGAACATCCAGTACAACTGGGTGAAGCTCGAGGAAACGCCCGAGA
TCCTCGCGAAGCTCGCGTCGGTGCAGATGCACGCGATCCAGACGTCCGGCAACTGCATCCGCAACATCACCGCCGACCAG
TTCGCGGGCGTGGCTCAGGATGAGGAGATCGATCCGCGTCCGTGGGCCGAGATCCTGCGCCAATGGTCGACGTTCCATCC
CGAATTCGCGTGGCTGCCGCGCAAGTTCAAGATCGCCGTGTCCGGCTCGAAGGCAGACCGCGCGGCCGTGCAGATCCACG
ATCTCGGCGTCTACCTGAAGAAGAACGAGGCGGGCGAAGTGGTCGCTAGCATCCTCGCGGGCGGCGGCCTCGGCCGCACG
CCGATCGTCGGCGCGATTATCCGCGAGAACCTGCCGTGGCAGCACCTCCTCACCTATTGCGAGGCGGCGCTGCGCGTCTA
CAACCGCTTCGGCCGCCGCGACAACCTGTTCAAGGCGCGGATCAAGATCCTCGTGAAGGCGCTGTCGCCTGCGAAGTTCT
CGCAGATGGTCGAAGAGGAATGGCAGCATCTGAAGGACGGCCCGTCGACGCTCACGCAAGCCGAAGTCGACCGCGTGTCG
CAGTTCTTCCAGCCGCCCGCCTACGAGAAGCTCGCCGACACCGACGCGTCGTTCGAGCAGCATCTGCTCGAGAACCGCGC
GTTCGCGCGCTGGGTCGAGCGCAACGTCGCGCCGCACAAGGTGCCGGGGTACGCCGCCGTCACGCTTTCGCTGAAGAACC
ATCGCGTCGCGCCCGGCGACGCGAGCGCCGAGCAGATGGAGCAGGTCGCCGACTGGGCCGACGCCTATTCGTTCGGCGAG
CTGCGCGTGTCGCACGAGCAGAACCTGATTCTCGCGAACGTGAAGAAGCGCGATCTGTTCGCGGTATGGGAAAAGGCGAA
GGCGGCCGGCTTCGCGACGCCGAACGTCGGCCTGCTGACCGACATCATCGCGTGCCCGGGCGGCGACTTCTGCTCGCTCG
CGAACGCGAAGTCGATTCCGATCGCGCTCGCGATCCAGCAGCGCTTCGACGATCTCGACTACGTGTACGACCTGGGCGAC
GTGTCGCTCAACATCTCGGGCTGCATGAACTCGTGCGGACACCACCACGTCGGCAACATCGGCATTCTCGGCGTCGACAA
GGACGGCGCCGAGTGGTATCAGGTGTCGCTCGGCGGCGAGCAGGGCACGGGCGCGGGCGGCGCGCGCCTCGGCCGCGTGA
TCGGCCCGTCGTTCTCCGCGGAGGAGGTGCCCGACGTGATCTCGAAGCTGATCGACACGTTCGTCGAGTCGCGCATCGAC
GGCGAGCGCTTCATCGACACGTACGATCGCATCGGCATCGCGCCGTTCAAGGAGCGCGTCTACGCGGCGCGCCAGACCGC
GCACGCGTAA

Upstream 100 bases:

>100_bases
TTTTAGTCGTTTGAAATATAAGGGGAGTTTATTACGATTGCCCCGTGTTTTTCAAATATGGATATCTGTAATCGTCATTT
GCACATGACCGGCCGGGCGG

Downstream 100 bases:

>100_bases
CCCAGCGTAGAGGAATCTGCAGATGGCTTTGATTATCAAGAATCGCGAAGTGATCGACGACGCGTGGCAGGTCGTGCGCG
CGGCCGAAGACGGCACGCTG

Product: sulfite reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 589; Mature: 588

Protein sequence:

>589_residues
MADSARTVQDSGAAWLGRRAVISSKPWGPRMYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRH
AYMHRIAIPYGNLRSVQLRMLARIAREHDRGYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQ
FAGVAQDEEIDPRPWAEILRQWSTFHPEFAWLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNEAGEVVASILAGGGLGRT
PIVGAIIRENLPWQHLLTYCEAALRVYNRFGRRDNLFKARIKILVKALSPAKFSQMVEEEWQHLKDGPSTLTQAEVDRVS
QFFQPPAYEKLADTDASFEQHLLENRAFARWVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGE
LRVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGD
VSLNISGCMNSCGHHHVGNIGILGVDKDGAEWYQVSLGGEQGTGAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRID
GERFIDTYDRIGIAPFKERVYAARQTAHA

Sequences:

>Translated_589_residues
MADSARTVQDSGAAWLGRRAVISSKPWGPRMYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRH
AYMHRIAIPYGNLRSVQLRMLARIAREHDRGYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQ
FAGVAQDEEIDPRPWAEILRQWSTFHPEFAWLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNEAGEVVASILAGGGLGRT
PIVGAIIRENLPWQHLLTYCEAALRVYNRFGRRDNLFKARIKILVKALSPAKFSQMVEEEWQHLKDGPSTLTQAEVDRVS
QFFQPPAYEKLADTDASFEQHLLENRAFARWVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGE
LRVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGD
VSLNISGCMNSCGHHHVGNIGILGVDKDGAEWYQVSLGGEQGTGAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRID
GERFIDTYDRIGIAPFKERVYAARQTAHA
>Mature_588_residues
ADSARTVQDSGAAWLGRRAVISSKPWGPRMYQYDQYDQTIVDERVAQYRDQVRRRLSGELSEDEFRPLRLQNGLYMQRHA
YMHRIAIPYGNLRSVQLRMLARIAREHDRGYGHFSTRSNIQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQF
AGVAQDEEIDPRPWAEILRQWSTFHPEFAWLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNEAGEVVASILAGGGLGRTP
IVGAIIRENLPWQHLLTYCEAALRVYNRFGRRDNLFKARIKILVKALSPAKFSQMVEEEWQHLKDGPSTLTQAEVDRVSQ
FFQPPAYEKLADTDASFEQHLLENRAFARWVERNVAPHKVPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGEL
RVSHEQNLILANVKKRDLFAVWEKAKAAGFATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGDV
SLNISGCMNSCGHHHVGNIGILGVDKDGAEWYQVSLGGEQGTGAGGARLGRVIGPSFSAEEVPDVISKLIDTFVESRIDG
ERFIDTYDRIGIAPFKERVYAARQTAHA

Specific function: This Enzyme Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. [C]

COG id: COG0155

COG function: function code P; Sulfite reductase, beta subunit (hemoprotein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nitrite and sulfite reductase 4Fe-4S domain family [H]

Homologues:

None

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005117
- InterPro:   IPR006067
- InterPro:   IPR006066 [H]

Pfam domain/function: PF01077 NIR_SIR; PF03460 NIR_SIR_ferr [H]

EC number: =1.8.7.1 [H]

Molecular weight: Translated: 65963; Mature: 65832

Theoretical pI: Translated: 7.29; Mature: 7.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSARTVQDSGAAWLGRRAVISSKPWGPRMYQYDQYDQTIVDERVAQYRDQVRRRLSGE
CCCCCCCHHCCCCHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LSEDEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSVQLRMLARIAREHDRGYGHFSTRSN
CCCCCCCCEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
IQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQFAGVAQDEEIDPRPWAEILR
CEEEEEEECCCHHHHHHHHHHHHHEEECCCCHHHCCCHHHHCCCCCCCCCCCCHHHHHHH
QWSTFHPEFAWLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNEAGEVVASILAGGGLGRT
HHHCCCCCHHCCCCEEEEEECCCCCCHHEEEEEECEEEEECCCHHHHHHHHHHCCCCCCC
PIVGAIIRENLPWQHLLTYCEAALRVYNRFGRRDNLFKARIKILVKALSPAKFSQMVEEE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
WQHLKDGPSTLTQAEVDRVSQFFQPPAYEKLADTDASFEQHLLENRAFARWVERNVAPHK
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGELRVSHEQNLILANVKKRDLF
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCHHHHH
AVWEKAKAAGFATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGD
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHCCCHHHHEECCC
VSLNISGCMNSCGHHHVGNIGILGVDKDGAEWYQVSLGGEQGTGAGGARLGRVIGPSFSA
CEEEHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCH
EEVPDVISKLIDTFVESRIDGERFIDTYDRIGIAPFKERVYAARQTAHA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ADSARTVQDSGAAWLGRRAVISSKPWGPRMYQYDQYDQTIVDERVAQYRDQVRRRLSGE
CCCCCCHHCCCCHHHCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
LSEDEFRPLRLQNGLYMQRHAYMHRIAIPYGNLRSVQLRMLARIAREHDRGYGHFSTRSN
CCCCCCCCEECCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
IQYNWVKLEETPEILAKLASVQMHAIQTSGNCIRNITADQFAGVAQDEEIDPRPWAEILR
CEEEEEEECCCHHHHHHHHHHHHHEEECCCCHHHCCCHHHHCCCCCCCCCCCCHHHHHHH
QWSTFHPEFAWLPRKFKIAVSGSKADRAAVQIHDLGVYLKKNEAGEVVASILAGGGLGRT
HHHCCCCCHHCCCCEEEEEECCCCCCHHEEEEEECEEEEECCCHHHHHHHHHHCCCCCCC
PIVGAIIRENLPWQHLLTYCEAALRVYNRFGRRDNLFKARIKILVKALSPAKFSQMVEEE
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
WQHLKDGPSTLTQAEVDRVSQFFQPPAYEKLADTDASFEQHLLENRAFARWVERNVAPHK
HHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
VPGYAAVTLSLKNHRVAPGDASAEQMEQVADWADAYSFGELRVSHEQNLILANVKKRDLF
CCCEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCCEEEEECCHHHHH
AVWEKAKAAGFATPNVGLLTDIIACPGGDFCSLANAKSIPIALAIQQRFDDLDYVYDLGD
HHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEHHHCCCHHHHEECCC
VSLNISGCMNSCGHHHVGNIGILGVDKDGAEWYQVSLGGEQGTGAGGARLGRVIGPSFSA
CEEEHHHHHHCCCCCCCCCEEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHCCCCCH
EEVPDVISKLIDTFVESRIDGERFIDTYDRIGIAPFKERVYAARQTAHA
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA