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The map label for this gene is sucD [H]

Identifier: 83720356

GI number: 83720356

Start: 745212

End: 746093

Strand: Direct

Name: sucD [H]

Synonym: BTH_I0647

Alternate gene names: 83720356

Gene position: 745212-746093 (Clockwise)

Preceding gene: 83721087

Following gene: 83719287

Centisome position: 19.56

GC content: 65.76

Gene sequence:

>882_bases
ATGTCGATTCTGATCAACAAAGACACGAAGGTCATCACGCAGGGCATCACCGGCAAGACCGGCCAGTTCCACACGCGCGC
CTGCCGTGAATACGCAAACGGCCGCGAAGCGTTCGTCGCGGGCGTGAACCCGAAGCGCGCCGGCGAAGATTTCGAAGGCA
TTCCGATCTACGCGAGCGTCAAGGAAGCGAAGGCGGAAACCGGCGCGACCGTGTCGGTCATCTACGTGCCGCCCGCGGGC
GCCGCCGCGGCGATCTGGGAAGCGGTCGAGGCCGATCTCGATCTCGCGATCTGCATCACGGAAGGCATCCCCGTGCGCGA
CATGATCGAAGTGAAGGACCGCATGCGCCGCGAAGGCCGCAAGACGCTGCTGCTCGGGCCGAACTGCCCGGGCACGATCA
CGCCGGACGAGCTGAAGATCGGCATCATGCCGGGCCACATCCACCGCAAGGGCCGCATCGGCGTCGTGTCGCGCTCGGGC
ACGCTGACGTACGAGGCGGTCGCGCAACTGACGGCGCTTGGCCTTGGCCAATCGTCGGCGGTCGGCATCGGCGGCGACCC
GATCAACGGCCTGAAGCACATCGACGTGATGAAGATGTTCAACGACGATCCGGATACGGACGCGGTCGTGATGATCGGCG
AGATCGGCGGTCCGGACGAGGCCAACGCGGCGCAGTGGATCAAGGACAACATGAAGAAGCCCGTCGTTGGCTTCATCGCG
GGCGTCACGGCGCCTCCGGGCAAGCGCATGGGCCACGCCGGCGCGCTGATCTCGGGCGGTGCGGACACGGCCGAAGCGAA
GCTGGAAATCATGGAAGCGTGCGGCATCAAGGTCACGCGCAATCCGTCGGAAATGGGCCGCCTGCTGAAGGCCGCGCTGT
AA

Upstream 100 bases:

>100_bases
CGGGAAGACTCGGGCAGTCCCGCGTTTTTCCGAGCGCAACATTGAACACGCATGGCGGCGCGGTTTCTTTTCGCGACGCC
GATCGAACAGAGGTCATTAC

Downstream 100 bases:

>100_bases
GCGCCGGTTCCATCGCCACAAAAAACGCCGGTTCCGCCGGCGTTTTTTGTTATGCTCGCGCAATCGTTTCGTAAGGCCCC
CCGTCGGGCGGCCCGTCGCG

Product: succinyl-CoA synthetase subunit alpha

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit alpha; SCS-alpha; Vegetative protein 239; VEG239 [H]

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKRAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAQWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGIKVTRNPSEMGRLLKAAL

Sequences:

>Translated_293_residues
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKRAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAG
AAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSG
TLTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAQWIKDNMKKPVVGFIA
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGIKVTRNPSEMGRLLKAAL
>Mature_292_residues
SILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKRAGEDFEGIPIYASVKEAKAETGATVSVIYVPPAGA
AAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGRKTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGT
LTYEAVAQLTALGLGQSSAVGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAQWIKDNMKKPVVGFIAG
VTAPPGKRMGHAGALISGGADTAEAKLEIMEACGIKVTRNPSEMGRLLKAAL

Specific function: Unknown

COG id: COG0074

COG function: function code C; Succinyl-CoA synthetase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the succinate/malate CoA ligase alpha subunit family [H]

Homologues:

Organism=Homo sapiens, GI109452591, Length=288, Percent_Identity=54.8611111111111, Blast_Score=270, Evalue=9e-73,
Organism=Homo sapiens, GI38569423, Length=208, Percent_Identity=30.2884615384615, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI38569421, Length=208, Percent_Identity=30.2884615384615, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1786949, Length=293, Percent_Identity=54.9488054607508, Blast_Score=317, Evalue=7e-88,
Organism=Escherichia coli, GI1786513, Length=185, Percent_Identity=28.1081081081081, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17550194, Length=296, Percent_Identity=53.0405405405405, Blast_Score=299, Evalue=1e-81,
Organism=Caenorhabditis elegans, GI17553126, Length=296, Percent_Identity=53.0405405405405, Blast_Score=295, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI17557344, Length=254, Percent_Identity=26.3779527559055, Blast_Score=78, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17551266, Length=254, Percent_Identity=26.3779527559055, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6324716, Length=296, Percent_Identity=47.972972972973, Blast_Score=265, Evalue=6e-72,
Organism=Drosophila melanogaster, GI21356559, Length=292, Percent_Identity=49.3150684931507, Blast_Score=284, Evalue=5e-77,
Organism=Drosophila melanogaster, GI28574296, Length=292, Percent_Identity=53.4246575342466, Blast_Score=274, Evalue=4e-74,
Organism=Drosophila melanogaster, GI281363477, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363475, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI281363473, Length=253, Percent_Identity=26.8774703557312, Blast_Score=76, Evalue=3e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017440
- InterPro:   IPR003781
- InterPro:   IPR005810
- InterPro:   IPR005811
- InterPro:   IPR016040
- InterPro:   IPR016102 [H]

Pfam domain/function: PF02629 CoA_binding; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 30821; Mature: 30690

Theoretical pI: Translated: 7.03; Mature: 7.03

Prosite motif: PS01216 SUCCINYL_COA_LIG_1 ; PS00399 SUCCINYL_COA_LIG_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKRAGEDFEGIPIYASV
CEEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCCEEEEEH
KEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGR
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSA
EEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAQWIKDNMKKPVVGFIA
ECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCHHHHEE
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGIKVTRNPSEMGRLLKAAL
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHCC
>Mature Secondary Structure 
SILINKDTKVITQGITGKTGQFHTRACREYANGREAFVAGVNPKRAGEDFEGIPIYASV
EEEEECCCEEEEECCCCCCCCHHHHHHHHHCCCCEEEEECCCHHHCCCCCCCCEEEEEH
KEAKAETGATVSVIYVPPAGAAAAIWEAVEADLDLAICITEGIPVRDMIEVKDRMRREGR
HHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCC
KTLLLGPNCPGTITPDELKIGIMPGHIHRKGRIGVVSRSGTLTYEAVAQLTALGLGQSSA
EEEEECCCCCCCCCCCCEEEEEECCCEECCCCEEEEECCCCCHHHHHHHHHHHCCCCCCE
VGIGGDPINGLKHIDVMKMFNDDPDTDAVVMIGEIGGPDEANAAQWIKDNMKKPVVGFIA
ECCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHCCCCCHHHHEE
GVTAPPGKRMGHAGALISGGADTAEAKLEIMEACGIKVTRNPSEMGRLLKAAL
CCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHCCCEEECCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377; 9298659 [H]