Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 83721087

GI number: 83721087

Start: 743899

End: 745065

Strand: Direct

Name: sucC [H]

Synonym: BTH_I0646

Alternate gene names: 83721087

Gene position: 743899-745065 (Clockwise)

Preceding gene: 83719184

Following gene: 83720356

Centisome position: 19.53

GC content: 63.24

Gene sequence:

>1167_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAATTCGGAGTCGCGGTACCGCGCGGCAAGCCGGCGTTCTC
GGTGGACGAGGCCGTCAAGGTGGCGGAAGAGCTGGGCGGCCCGGTCTGGGTCGTCAAGGCCCAGATTCATGCGGGCGGCC
GCGGCAAGGGCGGCGGCGTGAAGGTCGCGAAGTCGCTCGACCAAGTGCGCGAGTACGCGAACCAGATCCTCGGCATGCAG
CTGAAGACGCACCAGACGGGCCCGGAAGGCCAGAAGGTCAACCGTCTGCTGATCGAGGAAGGCGCGGACATCAAGAAGGA
ACTGTATGTCGGCATCGTGATCGATCGCGTGTCGCAGAAGGTCGTCGTGATGGCGTCGAGCGAAGGCGGCATGGACATCG
AGGAAGTCGCGGAAAAGACGCCGGAAGCGATCCACAAGGTCGCGGTCGAGCCGTCGACGGGCCTGCAGGACGCCGAAGCC
GACGATCTCGCGAAGAAGATCGGCGTGCCGGATGCGTCGATTCCGCAAGCGCGGGAAATCCTGAAGGGCCTGTACAAGTC
GTTCTGGGAAACGGACGCGTCGCTCGCCGAAATCAACCCGCTCGTGCTGACGGGCGACGGCAAGGTGATCGCGCTCGACG
CGAAGTTCAACTTCGATTCGAACGCGCTGTTCCGCCATCCGGAAATCGTCGCGTACCGCGATCTGGACGAAGAAGATCCG
GCTGAAATCGAAGCGTCGAAGTTCGACCTCGCGTACATCTCGCTCGACGGCAACATCGGCTGCCTCGTGAACGGCGCGGG
CCTCGCGATGGCGACGATGGACACGATCAAGCTGTTCGGCGGCGAACCGGCCAACTTCCTCGACGTGGGCGGCGGCGCGA
CGACCGAGAAGGTCACCGAAGCGTTCAAGCTGATGCTGAAGAACCCGGGCCTGAAGGCCATCCTTGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCGGAAGGCGTGATCGCCGGCTCGAAGGCGGTGAACCTGAACGTGCCGCTCGTCGT
GCGCATGAAGGGCACGAACGAAGACCTCGGCAAGAAGATGCTCGCGGAATCCGGCCTGCCGATCATCTCGGCGGACAGCA
TGGAAGAAGCGGCGCAGAAGGTCGTCGCGGCTGCTGCGGGCAAGTAA

Upstream 100 bases:

>100_bases
CTCGGACAGTGCGAAGGAATGAGGGCGAACGCTTGAATCGTCAGAAGAAGCGATCGTCAATCGACTTTTTTAGCCAACTC
ACAGACTGAAGGAATCACGC

Downstream 100 bases:

>100_bases
CGAGCGCCTGCATCCCTGGCGCCGCGCGCCAGGCCCCGAAGCGGGGCGGGAAGACTCGGGCAGTCCCGCGTTTTTCCGAG
CGCAACATTGAACACGCATG

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYANQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSTGLQDAEA
DDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK

Sequences:

>Translated_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYANQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSTGLQDAEA
DDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK
>Mature_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLDQVREYANQILGMQ
LKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQKVVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSTGLQDAEA
DDLAKKIGVPDASIPQAREILKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLAESGLPIISADSMEEAAQKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=47.8149100257069, Blast_Score=357, Evalue=7e-99,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=45.6919060052219, Blast_Score=327, Evalue=1e-89,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=45.6824512534819, Blast_Score=309, Evalue=3e-84,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=53.6082474226804, Blast_Score=404, Evalue=1e-114,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=46.8193384223919, Blast_Score=352, Evalue=2e-97,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=44.8717948717949, Blast_Score=329, Evalue=1e-90,
Organism=Saccharomyces cerevisiae, GI6321683, Length=393, Percent_Identity=47.0737913486005, Blast_Score=355, Evalue=9e-99,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=45.4081632653061, Blast_Score=334, Evalue=8e-92,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=44.1326530612245, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=44.1326530612245, Blast_Score=320, Evalue=1e-87,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=44.2748091603053, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=44.2748091603053, Blast_Score=319, Evalue=2e-87,
Organism=Drosophila melanogaster, GI281363475, Length=411, Percent_Identity=26.7639902676399, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363473, Length=411, Percent_Identity=26.7639902676399, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI281363477, Length=411, Percent_Identity=26.7639902676399, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41259; Mature: 41259

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLDQVREYANQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQK
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHEEEEEEECCCCE
VVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSTGLQDAEADDLAKKIGVPDASIPQAREI
EEEEECCCCCCCHHHHHHHCHHHHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHHCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LAESGLPIISADSMEEAAQKVVAAAAGK
HHHCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLDQVREYANQILGMQLKTHQTGPEGQKVNRLLIEEGADIKKELYVGIVIDRVSQK
HHHHHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHEEEEEEECCCCE
VVVMASSEGGMDIEEVAEKTPEAIHKVAVEPSTGLQDAEADDLAKKIGVPDASIPQAREI
EEEEECCCCCCCHHHHHHHCHHHHHHEECCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LKGLYKSFWETDASLAEINPLVLTGDGKVIALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHHCCCCHHHCCCEEEECCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEEHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LAESGLPIISADSMEEAAQKVVAAAAGK
HHHCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA