| Definition | Burkholderia thailandensis E264 chromosome chromosome I, complete sequence. |
|---|---|
| Accession | NC_007651 |
| Length | 3,809,201 |
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The map label for this gene is ydfG [H]
Identifier: 83720333
GI number: 83720333
Start: 1554502
End: 1555248
Strand: Reverse
Name: ydfG [H]
Synonym: BTH_I1378
Alternate gene names: 83720333
Gene position: 1555248-1554502 (Counterclockwise)
Preceding gene: 83719443
Following gene: 83719384
Centisome position: 40.83
GC content: 70.15
Gene sequence:
>747_bases ATGATCGTGTTCGTCACCGGTGCGTCGGCAGGTTTCGGCGCCGCCATCGCCCGCGCCTTCGTCAAGGGCGGCCACCGCGT CGTCGCCTCCGCTCGCCGCAAGGAGCGCCTCGATGCGCTCGCCGCCGAGCTCGGCGGCGCCCTGCTGCCGATCGAGCTCG ACGTGCGCGACCGCGCGGCCGTCGAGGCCGTGCCGGCCGCGCTGCCTGCGGAATTCGCCGCGATCGACGTCCTCGTCAAC AACGCGGGCCTCGCGCTCGGCGTCGAGCCCGCGCATCGGGCGAGCCTCGACGAGTGGCAGACGATGATCGACACCAACTG CTCGGGCCTCGTCACGGTCACGCGCACGCTGCTGCCCGGCATGGTCGAGCGCGGCCGCGGCCACATCTTCAACCTCGGCT CGGTCGCGGGCAGCTATCCATACCCGGGCGGCAACGTCTATGGCGCGACCAAGGCGTTCGTGCGCCAGTTCAGCCTGAAC CTGCGCGCCGACCTGATCGGCACGCCGCTGCGCGTCACCGATATCGAACCGGGCCTCTGCGGCGGCACCGAATTCTCGAA CGTGCGCTACCGCGGCGACGACGAGAAGGCGGCGAACGTCTACGCAAACGTCCAGCCGCTCACCGCCGAGGACATCGCCG ACACGATCTACTGGATCGCAACCCGTCCCGCGCACGTGAACATCAACACGATCGAGATGATGCCTGTCGCGCAGGCGCCC GCCGGTCTCACCGTCCATCGCGGCTGA
Upstream 100 bases:
>100_bases GCGAGCGTCGCAGACGGGCGCGCCGCTCCTTGCCGCACCGCCGCGATGTCAGTAGGCTAACGAGTTCCCCCCAGCAAGCA TCGTTTTAGGAGCTGCAGCA
Downstream 100 bases:
>100_bases TCGCGCCGCCGGGCCGTATAGGCGGCCCGGCGAAGGCAACATTCCGTTACGAATCAGGGGAATCGGGGTCGCCTGTTCCG GTAGAATGCGCGCCATGATC
Product: short chain dehydrogenase/reductase family oxidoreductase
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 248; Mature: 248
Protein sequence:
>248_residues MIVFVTGASAGFGAAIARAFVKGGHRVVASARRKERLDALAAELGGALLPIELDVRDRAAVEAVPAALPAEFAAIDVLVN NAGLALGVEPAHRASLDEWQTMIDTNCSGLVTVTRTLLPGMVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLN LRADLIGTPLRVTDIEPGLCGGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP AGLTVHRG
Sequences:
>Translated_248_residues MIVFVTGASAGFGAAIARAFVKGGHRVVASARRKERLDALAAELGGALLPIELDVRDRAAVEAVPAALPAEFAAIDVLVN NAGLALGVEPAHRASLDEWQTMIDTNCSGLVTVTRTLLPGMVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLN LRADLIGTPLRVTDIEPGLCGGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP AGLTVHRG >Mature_248_residues MIVFVTGASAGFGAAIARAFVKGGHRVVASARRKERLDALAAELGGALLPIELDVRDRAAVEAVPAALPAEFAAIDVLVN NAGLALGVEPAHRASLDEWQTMIDTNCSGLVTVTRTLLPGMVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLN LRADLIGTPLRVTDIEPGLCGGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP AGLTVHRG
Specific function: Catalyzes the NADP-dependent oxidation of L-allo- threonine and L-serine [H]
COG id: COG4221
COG function: function code R; Short-chain alcohol dehydrogenase of unknown specificity
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI109715829, Length=248, Percent_Identity=34.2741935483871, Blast_Score=130, Evalue=1e-30, Organism=Homo sapiens, GI7706318, Length=186, Percent_Identity=36.5591397849462, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI20149619, Length=186, Percent_Identity=30.6451612903226, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI40548397, Length=179, Percent_Identity=32.9608938547486, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI214010158, Length=179, Percent_Identity=32.9608938547486, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI214010156, Length=179, Percent_Identity=32.9608938547486, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI22758144, Length=179, Percent_Identity=32.9608938547486, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI157739938, Length=186, Percent_Identity=29.5698924731183, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI7657478, Length=183, Percent_Identity=36.0655737704918, Blast_Score=85, Evalue=6e-17, Organism=Homo sapiens, GI150247226, Length=183, Percent_Identity=34.9726775956284, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI4557649, Length=178, Percent_Identity=30.8988764044944, Blast_Score=82, Evalue=6e-16, Organism=Homo sapiens, GI22507405, Length=178, Percent_Identity=32.5842696629214, Blast_Score=81, Evalue=9e-16, Organism=Homo sapiens, GI7705855, Length=193, Percent_Identity=29.0155440414508, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI10190704, Length=228, Percent_Identity=28.0701754385965, Blast_Score=74, Evalue=1e-13, Organism=Homo sapiens, GI32483357, Length=210, Percent_Identity=27.6190476190476, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI19743808, Length=178, Percent_Identity=28.6516853932584, Blast_Score=71, Evalue=8e-13, Organism=Homo sapiens, GI19923817, Length=187, Percent_Identity=26.2032085561497, Blast_Score=70, Evalue=2e-12, Organism=Homo sapiens, GI40254992, Length=178, Percent_Identity=29.2134831460674, Blast_Score=69, Evalue=6e-12, Organism=Homo sapiens, GI50726952, Length=180, Percent_Identity=31.6666666666667, Blast_Score=65, Evalue=7e-11, Organism=Escherichia coli, GI1787820, Length=247, Percent_Identity=66.3967611336032, Blast_Score=352, Evalue=1e-98, Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=30.8016877637131, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI87082100, Length=180, Percent_Identity=34.4444444444444, Blast_Score=73, Evalue=2e-14, Organism=Escherichia coli, GI1786812, Length=242, Percent_Identity=27.6859504132231, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1786701, Length=200, Percent_Identity=28.5, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI71994604, Length=238, Percent_Identity=25.2100840336134, Blast_Score=80, Evalue=8e-16, Organism=Caenorhabditis elegans, GI71994600, Length=239, Percent_Identity=24.6861924686192, Blast_Score=77, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17559104, Length=241, Percent_Identity=25.7261410788382, Blast_Score=75, Evalue=2e-14, Organism=Caenorhabditis elegans, GI17538480, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562908, Length=188, Percent_Identity=28.7234042553192, Blast_Score=75, Evalue=4e-14, Organism=Caenorhabditis elegans, GI17562910, Length=247, Percent_Identity=26.3157894736842, Blast_Score=75, Evalue=5e-14, Organism=Caenorhabditis elegans, GI17560332, Length=245, Percent_Identity=27.7551020408163, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17560150, Length=184, Percent_Identity=28.804347826087, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17562990, Length=186, Percent_Identity=29.5698924731183, Blast_Score=70, Evalue=7e-13, Organism=Caenorhabditis elegans, GI17560676, Length=200, Percent_Identity=27, Blast_Score=70, Evalue=9e-13, Organism=Caenorhabditis elegans, GI17544670, Length=245, Percent_Identity=25.3061224489796, Blast_Score=68, Evalue=5e-12, Organism=Caenorhabditis elegans, GI17563726, Length=238, Percent_Identity=26.890756302521, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI193204405, Length=189, Percent_Identity=28.042328042328, Blast_Score=66, Evalue=2e-11, Organism=Caenorhabditis elegans, GI17562906, Length=188, Percent_Identity=26.5957446808511, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17560220, Length=191, Percent_Identity=28.2722513089005, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17565030, Length=249, Percent_Identity=28.1124497991968, Blast_Score=65, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17562904, Length=240, Percent_Identity=27.9166666666667, Blast_Score=64, Evalue=5e-11, Organism=Caenorhabditis elegans, GI17538182, Length=190, Percent_Identity=29.4736842105263, Blast_Score=64, Evalue=6e-11, Organism=Caenorhabditis elegans, GI71982365, Length=140, Percent_Identity=32.1428571428571, Blast_Score=64, Evalue=7e-11, Organism=Saccharomyces cerevisiae, GI6323882, Length=245, Percent_Identity=39.5918367346939, Blast_Score=169, Evalue=4e-43, Organism=Saccharomyces cerevisiae, GI6322067, Length=176, Percent_Identity=29.5454545454545, Blast_Score=73, Evalue=4e-14, Organism=Saccharomyces cerevisiae, GI6322227, Length=196, Percent_Identity=23.9795918367347, Blast_Score=66, Evalue=5e-12, Organism=Drosophila melanogaster, GI116007236, Length=251, Percent_Identity=33.4661354581673, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI21358495, Length=185, Percent_Identity=33.5135135135135, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI281364494, Length=247, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=1e-21, Organism=Drosophila melanogaster, GI116007238, Length=186, Percent_Identity=35.4838709677419, Blast_Score=94, Evalue=7e-20, Organism=Drosophila melanogaster, GI23397609, Length=229, Percent_Identity=29.6943231441048, Blast_Score=92, Evalue=5e-19, Organism=Drosophila melanogaster, GI28571526, Length=236, Percent_Identity=30.0847457627119, Blast_Score=91, Evalue=7e-19, Organism=Drosophila melanogaster, GI24584748, Length=179, Percent_Identity=32.4022346368715, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI161076933, Length=179, Percent_Identity=32.4022346368715, Blast_Score=89, Evalue=3e-18, Organism=Drosophila melanogaster, GI116007234, Length=251, Percent_Identity=32.6693227091633, Blast_Score=88, Evalue=5e-18, Organism=Drosophila melanogaster, GI24641232, Length=255, Percent_Identity=29.4117647058824, Blast_Score=88, Evalue=6e-18, Organism=Drosophila melanogaster, GI24663911, Length=248, Percent_Identity=29.4354838709677, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI21357041, Length=236, Percent_Identity=28.8135593220339, Blast_Score=86, Evalue=2e-17, Organism=Drosophila melanogaster, GI24643142, Length=176, Percent_Identity=32.3863636363636, Blast_Score=86, Evalue=3e-17, Organism=Drosophila melanogaster, GI24641388, Length=250, Percent_Identity=31.2, Blast_Score=83, Evalue=2e-16, Organism=Drosophila melanogaster, GI28571387, Length=250, Percent_Identity=29.6, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24644339, Length=234, Percent_Identity=27.3504273504274, Blast_Score=79, Evalue=2e-15, Organism=Drosophila melanogaster, GI24640442, Length=192, Percent_Identity=28.125, Blast_Score=79, Evalue=3e-15, Organism=Drosophila melanogaster, GI28574402, Length=185, Percent_Identity=32.4324324324324, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24584744, Length=185, Percent_Identity=32.4324324324324, Blast_Score=78, Evalue=6e-15, Organism=Drosophila melanogaster, GI24580925, Length=230, Percent_Identity=30.4347826086957, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24648693, Length=249, Percent_Identity=29.3172690763052, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI21355889, Length=249, Percent_Identity=29.3172690763052, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI24648944, Length=239, Percent_Identity=27.6150627615063, Blast_Score=72, Evalue=4e-13, Organism=Drosophila melanogaster, GI21355631, Length=169, Percent_Identity=28.4023668639053, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584752, Length=180, Percent_Identity=30.5555555555556, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI116007232, Length=186, Percent_Identity=35.4838709677419, Blast_Score=69, Evalue=3e-12, Organism=Drosophila melanogaster, GI281364892, Length=198, Percent_Identity=29.7979797979798, Blast_Score=67, Evalue=9e-12, Organism=Drosophila melanogaster, GI17737361, Length=192, Percent_Identity=30.7291666666667, Blast_Score=66, Evalue=2e-11,
Paralogues:
None
Copy number: 1300 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: 1.-.-.- [C]
Molecular weight: Translated: 26189; Mature: 26189
Theoretical pI: Translated: 6.36; Mature: 6.36
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 2.0 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIVFVTGASAGFGAAIARAFVKGGHRVVASARRKERLDALAAELGGALLPIELDVRDRAA CEEEEECCCCCHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHH VEAVPAALPAEFAAIDVLVNNAGLALGVEPAHRASLDEWQTMIDTNCSGLVTVTRTLLPG HHHHCCCCCHHHEEEEEEEECCCEEEECCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH MVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLNLRADLIGTPLRVTDIEPGLC HHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHCCCCEEEEECCCCCC GGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP CCCCCCCEEECCCCCHHHEEEECCCCCCHHHHHHHEEEEEECCCEEEEEEEEEEECCCCC AGLTVHRG CCEEEECC >Mature Secondary Structure MIVFVTGASAGFGAAIARAFVKGGHRVVASARRKERLDALAAELGGALLPIELDVRDRAA CEEEEECCCCCHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHCCEEEEEEECCCCHHH VEAVPAALPAEFAAIDVLVNNAGLALGVEPAHRASLDEWQTMIDTNCSGLVTVTRTLLPG HHHHCCCCCHHHEEEEEEEECCCEEEECCCHHHCCHHHHHHHHHCCCCCHHHHHHHHHHH MVERGRGHIFNLGSVAGSYPYPGGNVYGATKAFVRQFSLNLRADLIGTPLRVTDIEPGLC HHHCCCCCEEECCCCCCCCCCCCCCCCHHHHHHHHHHHCCCEEHHCCCCEEEEECCCCCC GGTEFSNVRYRGDDEKAANVYANVQPLTAEDIADTIYWIATRPAHVNINTIEMMPVAQAP CCCCCCCEEECCCCCHHHEEEECCCCCCHHHHHHHEEEEEECCCEEEEEEEEEEECCCCC AGLTVHRG CCEEEECC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11677608; 12644504 [H]