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The map label for this gene is yeaE [H]

Identifier: 83719990

GI number: 83719990

Start: 867602

End: 868447

Strand: Direct

Name: yeaE [H]

Synonym: BTH_I0755

Alternate gene names: 83719990

Gene position: 867602-868447 (Clockwise)

Preceding gene: 83721120

Following gene: 83721398

Centisome position: 22.78

GC content: 70.8

Gene sequence:

>846_bases
ATGACCAGCAGGCTCGAAACCGTCGCGCTGCCCGGCGGCGAACGCATACCGAAGCTCGGGCAGGGCACCTGGGAAATGGG
CGAGCGGCCCGCGAAGCGCGCGGCCGAGATCGCCGCGCTGCGCGAGGGCGTCGACCTCGGCATGACGCTCATCGATACGG
CCGAGATGTACGGCGACGGCGCGACCGAGACGCTCGTCGGCGACGCGCTCGCCGGCGTGCGCGACCGGCTGTTCACCGTG
AGCAAGGTGCTGCCGCATCATGCGAGCCGCGCGGGCGTTGTCGCCGCGTGCGAGGCGACGCTGAAACGCTTGCGCACCGA
TCGCGTCGATCTGTATCTGTTGCACTGGCGCGGCCCGGTTCCGCTCGCGGAGACGATCGCGGGCTTCGAAGCGCTGCGCG
ACGCCGGCAAGATCCGCTACTGGGGCGTCAGCAACTTCGACGTCGACGACATGGAGGCACTCGTCGCCGAAGCGGGCGGC
GCGGTGTGCGCGACGAACCAGATCCTCTACAACCTCGCACGCCGCGGCCCGGAGTTCGATCTGCTGCCGTGGCTCGCGCG
GCGCGGGATGCCGGCGATGGCGTACAGCCCGATCGATCACATGCGGTTGCCCAGGCGCACGGCGATCGACGAGATCGCGC
GCGAGCGCGGCGTGTCGCCGGCGCGCGTCGCGCTCGCATGGGTGCTCGGGCAGCCGAACGTGCTGGCGATTCCGAAGGCG
GGCAGCGTCGAACACGTGCGCGACAACCGCGCGGCGCTCGATTTCGTGCTGGGCGAGGACGAGCTCGCGCGGCTCGATGT
GCGGTTCAAGCCGCCGCGTGGCAAGCGGCCGCTCGAAATGCTGTAG

Upstream 100 bases:

>100_bases
CGCGCGATGCCGCCCGGCGCGCGTCGAATCGCTACACTGACGAATCACCCGCGGGCCGTGCGCGTCGCGCGCCGCGCTCG
AATACGTGACGAGGAACGAT

Downstream 100 bases:

>100_bases
CGCCGTGCGCGCCGCGGCAAGGCGGCCGGCTCGGGCAGCGGCTTGCTCGCGCAGCGTGCGGGCGGTGCGTCGCGGACGCC
ACGGCGCGCGCGGCCGATGC

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTSRLETVALPGGERIPKLGQGTWEMGERPAKRAAEIAALREGVDLGMTLIDTAEMYGDGATETLVGDALAGVRDRLFTV
SKVLPHHASRAGVVAACEATLKRLRTDRVDLYLLHWRGPVPLAETIAGFEALRDAGKIRYWGVSNFDVDDMEALVAEAGG
AVCATNQILYNLARRGPEFDLLPWLARRGMPAMAYSPIDHMRLPRRTAIDEIARERGVSPARVALAWVLGQPNVLAIPKA
GSVEHVRDNRAALDFVLGEDELARLDVRFKPPRGKRPLEML

Sequences:

>Translated_281_residues
MTSRLETVALPGGERIPKLGQGTWEMGERPAKRAAEIAALREGVDLGMTLIDTAEMYGDGATETLVGDALAGVRDRLFTV
SKVLPHHASRAGVVAACEATLKRLRTDRVDLYLLHWRGPVPLAETIAGFEALRDAGKIRYWGVSNFDVDDMEALVAEAGG
AVCATNQILYNLARRGPEFDLLPWLARRGMPAMAYSPIDHMRLPRRTAIDEIARERGVSPARVALAWVLGQPNVLAIPKA
GSVEHVRDNRAALDFVLGEDELARLDVRFKPPRGKRPLEML
>Mature_280_residues
TSRLETVALPGGERIPKLGQGTWEMGERPAKRAAEIAALREGVDLGMTLIDTAEMYGDGATETLVGDALAGVRDRLFTVS
KVLPHHASRAGVVAACEATLKRLRTDRVDLYLLHWRGPVPLAETIAGFEALRDAGKIRYWGVSNFDVDDMEALVAEAGGA
VCATNQILYNLARRGPEFDLLPWLARRGMPAMAYSPIDHMRLPRRTAIDEIARERGVSPARVALAWVLGQPNVLAIPKAG
SVEHVRDNRAALDFVLGEDELARLDVRFKPPRGKRPLEML

Specific function: Unknown

COG id: COG0656

COG function: function code R; Aldo/keto reductases, related to diketogulonate reductase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI310109922, Length=290, Percent_Identity=27.9310344827586, Blast_Score=89, Evalue=6e-18,
Organism=Homo sapiens, GI223468663, Length=296, Percent_Identity=27.7027027027027, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI24497577, Length=298, Percent_Identity=28.5234899328859, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI5174391, Length=298, Percent_Identity=28.5234899328859, Blast_Score=86, Evalue=5e-17,
Organism=Homo sapiens, GI24497585, Length=307, Percent_Identity=26.3843648208469, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI5453543, Length=310, Percent_Identity=26.4516129032258, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI45446745, Length=310, Percent_Identity=26.4516129032258, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI4503285, Length=310, Percent_Identity=26.4516129032258, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI310109920, Length=310, Percent_Identity=26.4516129032258, Blast_Score=82, Evalue=7e-16,
Organism=Homo sapiens, GI24497583, Length=312, Percent_Identity=25.9615384615385, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4502049, Length=303, Percent_Identity=28.3828382838284, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI41327764, Length=189, Percent_Identity=32.8042328042328, Blast_Score=65, Evalue=5e-11,
Organism=Homo sapiens, GI223718702, Length=187, Percent_Identity=29.9465240641711, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1788081, Length=281, Percent_Identity=49.1103202846975, Blast_Score=283, Evalue=8e-78,
Organism=Escherichia coli, GI1786400, Length=273, Percent_Identity=30.03663003663, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI87081735, Length=312, Percent_Identity=28.2051282051282, Blast_Score=101, Evalue=7e-23,
Organism=Escherichia coli, GI87082198, Length=280, Percent_Identity=29.6428571428571, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1787674, Length=281, Percent_Identity=28.8256227758007, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1788070, Length=303, Percent_Identity=26.7326732673267, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1789199, Length=324, Percent_Identity=30.5555555555556, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI48994888, Length=273, Percent_Identity=30.03663003663, Blast_Score=83, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17561298, Length=283, Percent_Identity=28.2685512367491, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=309, Percent_Identity=27.1844660194175, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI71998625, Length=271, Percent_Identity=25.830258302583, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI17552492, Length=275, Percent_Identity=25.4545454545455, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17537077, Length=300, Percent_Identity=26.3333333333333, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17550248, Length=302, Percent_Identity=25.1655629139073, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=302, Percent_Identity=24.1721854304636, Blast_Score=78, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6324694, Length=295, Percent_Identity=28.135593220339, Blast_Score=96, Evalue=6e-21,
Organism=Saccharomyces cerevisiae, GI6320576, Length=310, Percent_Identity=29.0322580645161, Blast_Score=88, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24657054, Length=306, Percent_Identity=27.4509803921569, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20129731, Length=300, Percent_Identity=27.6666666666667, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646159, Length=261, Percent_Identity=27.2030651340996, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 30790; Mature: 30659

Theoretical pI: Translated: 7.63; Mature: 7.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSRLETVALPGGERIPKLGQGTWEMGERPAKRAAEIAALREGVDLGMTLIDTAEMYGDG
CCCCCCEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCHHCCHHHHHHHHHHCCC
ATETLVGDALAGVRDRLFTVSKVLPHHASRAGVVAACEATLKRLRTDRVDLYLLHWRGPV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCC
PLAETIAGFEALRDAGKIRYWGVSNFDVDDMEALVAEAGGAVCATNQILYNLARRGPEFD
CHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCC
LLPWLARRGMPAMAYSPIDHMRLPRRTAIDEIARERGVSPARVALAWVLGQPNVLAIPKA
HHHHHHHCCCCCHHCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHEECCCCEEEECCC
GSVEHVRDNRAALDFVLGEDELARLDVRFKPPRGKRPLEML
CCHHHHHCCHHHEEEEECCCCCEEEEEEECCCCCCCCCCCC
>Mature Secondary Structure 
TSRLETVALPGGERIPKLGQGTWEMGERPAKRAAEIAALREGVDLGMTLIDTAEMYGDG
CCCCCEEECCCCCCCCCCCCCCHHHCCCHHHHHHHHHHHHHCHHCCHHHHHHHHHHCCC
ATETLVGDALAGVRDRLFTVSKVLPHHASRAGVVAACEATLKRLRTDRVDLYLLHWRGPV
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCEEEEEEECCCC
PLAETIAGFEALRDAGKIRYWGVSNFDVDDMEALVAEAGGAVCATNQILYNLARRGPEFD
CHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCCC
LLPWLARRGMPAMAYSPIDHMRLPRRTAIDEIARERGVSPARVALAWVLGQPNVLAIPKA
HHHHHHHCCCCCHHCCCHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHEECCCCEEEECCC
GSVEHVRDNRAALDFVLGEDELARLDVRFKPPRGKRPLEML
CCHHHHHCCHHHEEEEECCCCCEEEEEEECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]