Click here to switch to the map view.

The map label for this gene is xseA [H]

Identifier: 83719967

GI number: 83719967

Start: 852318

End: 854003

Strand: Direct

Name: xseA [H]

Synonym: BTH_I0743

Alternate gene names: 83719967

Gene position: 852318-854003 (Clockwise)

Preceding gene: 83718572

Following gene: 83719621

Centisome position: 22.38

GC content: 71.65

Gene sequence:

>1686_bases
ATGCGGCGCCCGCCTCGCCGCCGCGCATTCGAGCCGCCTGTGGATAACTCTGTGAAAAACTCCGCATCGAAGCGTGCGGC
GAGGCCATATGGCGGGCCTCCGGTCGGCGGGGGGGCGGGTTGGATTCGAAAAAAATCCATTGGAATCATATATTTGATCG
AAATCATCAGGGGTTTCGGGGCGATTGTTACAACACCGTCCCTGTTTCGCGCGCCGTGTGGACACCTGGGCGGCGCGCAC
GTGCGGCTTGCCGTGCGCGCCGAGGCGGTCTATCGTTGGGCGCCCGAAATCTCCCGATCGTCCATGCATTCCGAAACCAC
TTTCGCCGGCTCCGGCGGCGCGCCTGCCGGCGACGGCGTCATTCCCGTGTCCGCGCTCAACCGCGCGATCGGCACGATGC
TCGAGCGCACGTTCCCGCTGCTGTGGGTGGCGGGCGAAGTGTCGAACTTCACGCGCGCGGCGAGCGGCCACTGGTATTTC
TCGATCAAGGATCAGCAGGCGCAGATGCGTTGCGTGATGTTCCGCGGCCGCGCGCAGCATGCGGAGTTCACGCCGCGCGA
AGGAGACAAGATCGAAGTGCGCGCGCTCGTCACGATGTACGAGCCGCGCGGCGAAGTGCAACTGAACGTCGAGGCGGTTC
GGCGCACCGGGCAGGGGCGGCTTTACGAAGCGTTCCTGCGGCTGAAGGCGCAGCTCGAGGCCGAAGGGCTCTTCGCGCCC
GAGCGCAAGCGGGCGCTGCCGACGCATCCGCGCGCGATCGGCGTCGTCACGTCGCTGCAGGCGGCCGCGTTGCGCGACGT
GCTGACGACGCTCGCGCGCCGCGCGCCGCACGTGCCGGTGATCGTCTATCCGGCGCCCGTGCAGGGCGCGGGCGCGGCGG
AGAAGCTCGCCGCGATGGTCGCGACCGCGAGCGCGCGGCGCGAGGTCGACGTGCTGATCGTCTGCCGCGGCGGCGGCTCG
ATCGAGGACTTGTGGTCGTTCAACGACGAGGCGCTCGCGCGCGCGATCGCGGCGAGCGAGGTGCCTGTCGTGTGCGGCGT
CGGCCACGAGACCGATTTCACGATCGCCGATTTCGCGGCCGACGTGCGCGCGCCGACGCCGACCGGCGCGGCCGAGCTCG
TGAGCCCGCAGCGCGCGCTGTTGCTGCGCGAGCTGGGCGAGCGGCAGAACGCGCTCGCGCGCGGCCTGCGGCGCGGCCTC
GATGCGCGCGCGCAACAGCTCGACTGGCTCGCGCGCCGGCTGATCAGCCCGGCCGAGCGTCTGCAGCGTCAGTCCATGCA
CGTGGGACAGCTCGCCGCGCGGCTCGCGGCGGCGGGCGCGCGGCCGGTGCGCGATGCGCGCGCGCGTTTCGCGCTCGTGC
AACTGCGCTGGCAGCGCGCGCGGCCCGACGTCGCGCCCGCGCGGCAGGTGCTCGCGACGCTCGCGCAAAGGCTCGATGCG
ACGCTGCGGCGACGCGTCGAACGCGATACCGCGCGCGTCGCCGCATGCGCGGCGCGGCTCGAGGTGCTGAGCCCGCAGCG
CACGCTGGAGCGCGGCTATGCCGCACTCATCGACACGCAGACGGGCCGCGCGGTGCGCGCGCCCGCGGCGCTCAAGCCGC
AGCGCCGGCTGACCGTGCATCTCGCGGAAGGCTCCGCCGACGTGTCGCTCGCCGACGTGCAACCGCGCCTTTCGGATACG
TTCTGA

Upstream 100 bases:

>100_bases
ACGTTTCTCCGGATGGCGGCGGGCGGCCGCGCGGTCTTCTCTTCGAAAGGCGGCACTCTAGCGCGCCCGCCGCGCGGCCC
GCAAGTCGCGCGGGCGCCGC

Downstream 100 bases:

>100_bases
AGACGCGCCGCGCGTGCGGCACGCGGTGCGCGCGCGCCGTTTGGCGCGTCGCGCATGCCGCGTCGACGTCGATTTTTCGG
ATATGACGGATAAAGGCCCG

Product: exodeoxyribonuclease VII large subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease VII large subunit; Exonuclease VII large subunit [H]

Number of amino acids: Translated: 561; Mature: 561

Protein sequence:

>561_residues
MRRPPRRRAFEPPVDNSVKNSASKRAARPYGGPPVGGGAGWIRKKSIGIIYLIEIIRGFGAIVTTPSLFRAPCGHLGGAH
VRLAVRAEAVYRWAPEISRSSMHSETTFAGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYF
SIKDQQAQMRCVMFRGRAQHAEFTPREGDKIEVRALVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAP
ERKRALPTHPRAIGVVTSLQAAALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMVATASARREVDVLIVCRGGGS
IEDLWSFNDEALARAIAASEVPVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQNALARGLRRGL
DARAQQLDWLARRLISPAERLQRQSMHVGQLAARLAAAGARPVRDARARFALVQLRWQRARPDVAPARQVLATLAQRLDA
TLRRRVERDTARVAACAARLEVLSPQRTLERGYAALIDTQTGRAVRAPAALKPQRRLTVHLAEGSADVSLADVQPRLSDT
F

Sequences:

>Translated_561_residues
MRRPPRRRAFEPPVDNSVKNSASKRAARPYGGPPVGGGAGWIRKKSIGIIYLIEIIRGFGAIVTTPSLFRAPCGHLGGAH
VRLAVRAEAVYRWAPEISRSSMHSETTFAGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYF
SIKDQQAQMRCVMFRGRAQHAEFTPREGDKIEVRALVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAP
ERKRALPTHPRAIGVVTSLQAAALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMVATASARREVDVLIVCRGGGS
IEDLWSFNDEALARAIAASEVPVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQNALARGLRRGL
DARAQQLDWLARRLISPAERLQRQSMHVGQLAARLAAAGARPVRDARARFALVQLRWQRARPDVAPARQVLATLAQRLDA
TLRRRVERDTARVAACAARLEVLSPQRTLERGYAALIDTQTGRAVRAPAALKPQRRLTVHLAEGSADVSLADVQPRLSDT
F
>Mature_561_residues
MRRPPRRRAFEPPVDNSVKNSASKRAARPYGGPPVGGGAGWIRKKSIGIIYLIEIIRGFGAIVTTPSLFRAPCGHLGGAH
VRLAVRAEAVYRWAPEISRSSMHSETTFAGSGGAPAGDGVIPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYF
SIKDQQAQMRCVMFRGRAQHAEFTPREGDKIEVRALVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAP
ERKRALPTHPRAIGVVTSLQAAALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMVATASARREVDVLIVCRGGGS
IEDLWSFNDEALARAIAASEVPVVCGVGHETDFTIADFAADVRAPTPTGAAELVSPQRALLLRELGERQNALARGLRRGL
DARAQQLDWLARRLISPAERLQRQSMHVGQLAARLAAAGARPVRDARARFALVQLRWQRARPDVAPARQVLATLAQRLDA
TLRRRVERDTARVAACAARLEVLSPQRTLERGYAALIDTQTGRAVRAPAALKPQRRLTVHLAEGSADVSLADVQPRLSDT
F

Specific function: Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides [H]

COG id: COG1570

COG function: function code L; Exonuclease VII, large subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xseA family [H]

Homologues:

Organism=Escherichia coli, GI1788856, Length=441, Percent_Identity=40.8163265306122, Blast_Score=326, Evalue=3e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003753
- InterPro:   IPR020579
- InterPro:   IPR004365 [H]

Pfam domain/function: PF02601 Exonuc_VII_L; PF01336 tRNA_anti [H]

EC number: =3.1.11.6 [H]

Molecular weight: Translated: 60962; Mature: 60962

Theoretical pI: Translated: 11.58; Mature: 11.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRPPRRRAFEPPVDNSVKNSASKRAARPYGGPPVGGGAGWIRKKSIGIIYLIEIIRGFG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCC
AIVTTPSLFRAPCGHLGGAHVRLAVRAEAVYRWAPEISRSSMHSETTFAGSGGAPAGDGV
HHHCCCHHHHCCCCCCCCCEEEEEEEHHHHHHHCCHHHHHHCCCCCEECCCCCCCCCCCE
IPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQH
EEHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCC
AEFTPREGDKIEVRALVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAP
CCCCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
ERKRALPTHPRAIGVVTSLQAAALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
ATASARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASEVPVVCGVGHETDFTIADFAA
HHHHCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHH
DVRAPTPTGAAELVSPQRALLLRELGERQNALARGLRRGLDARAQQLDWLARRLISPAER
HCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHH
LQRQSMHVGQLAARLAAAGARPVRDARARFALVQLRWQRARPDVAPARQVLATLAQRLDA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TLRRRVERDTARVAACAARLEVLSPQRTLERGYAALIDTQTGRAVRAPAALKPQRRLTVH
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCEEECCCCCCCCCEEEEE
LAEGSADVSLADVQPRLSDTF
EECCCCCEEEECCCCHHCCCC
>Mature Secondary Structure
MRRPPRRRAFEPPVDNSVKNSASKRAARPYGGPPVGGGAGWIRKKSIGIIYLIEIIRGFG
CCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHCC
AIVTTPSLFRAPCGHLGGAHVRLAVRAEAVYRWAPEISRSSMHSETTFAGSGGAPAGDGV
HHHCCCHHHHCCCCCCCCCEEEEEEEHHHHHHHCCHHHHHHCCCCCEECCCCCCCCCCCE
IPVSALNRAIGTMLERTFPLLWVAGEVSNFTRAASGHWYFSIKDQQAQMRCVMFRGRAQH
EEHHHHHHHHHHHHHHHCCEEEEECCHHHHHHHCCCCEEEEECCCHHHHHHHHHCCCCCC
AEFTPREGDKIEVRALVTMYEPRGEVQLNVEAVRRTGQGRLYEAFLRLKAQLEAEGLFAP
CCCCCCCCCEEEEEEEEEEECCCCCEEEEHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCC
ERKRALPTHPRAIGVVTSLQAAALRDVLTTLARRAPHVPVIVYPAPVQGAGAAEKLAAMV
HHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHH
ATASARREVDVLIVCRGGGSIEDLWSFNDEALARAIAASEVPVVCGVGHETDFTIADFAA
HHHHCCCCEEEEEEECCCCCHHHHHCCCHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHH
DVRAPTPTGAAELVSPQRALLLRELGERQNALARGLRRGLDARAQQLDWLARRLISPAER
HCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCHHHH
LQRQSMHVGQLAARLAAAGARPVRDARARFALVQLRWQRARPDVAPARQVLATLAQRLDA
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
TLRRRVERDTARVAACAARLEVLSPQRTLERGYAALIDTQTGRAVRAPAALKPQRRLTVH
HHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCEEEEECCCCCEEECCCCCCCCCEEEEE
LAEGSADVSLADVQPRLSDTF
EECCCCCEEEECCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA