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The map label for this gene is ttuB [H]

Identifier: 83719833

GI number: 83719833

Start: 2588666

End: 2589943

Strand: Direct

Name: ttuB [H]

Synonym: BTH_I2297

Alternate gene names: 83719833

Gene position: 2588666-2589943 (Clockwise)

Preceding gene: 83719128

Following gene: 83720963

Centisome position: 67.96

GC content: 67.06

Gene sequence:

>1278_bases
ATGTCCGCAACGCTTGCGATTCGCCGCTGGTGGACGATCATGCCGATCGTCTTCATCACGTACAGCCTCGCGTACCTCGA
TCGCGCGAACTACGGCTTCGCCGCCGCGGCCGGGATCAATCAGGACCTCGGCATCAGCAAGGGGTTGTCGTCGCTGATCG
GCGCGCTGTTCTTCCTCGGCTACTTCTTCTTCCAGATTCCGGGCGCGATCTATGCGGAGCGGCGCAGCGTGAAGACGCTC
GTGTTCTGGAGCCTCGTGCTGTGGGGCGCGTGCGCGTCGCTCACGGGCATCGTCAGCAACATCCCGTCGCTGATGGCGAT
CCGCTTCCTGCTCGGCGTCGTCGAGGCGGCCGTGATGCCCGCGATGCTGATCTTCATCAGCAACTGGTTCACGAAGCGCG
AGCGCTCGCGCGCGAATACGTTCCTCATTCTCGGCAATCCGGTCACGGTGCTGTGGATGTCGGTCGTCTCCGGCTATCTC
GTCCACGAGTTCGGCTGGCGCCACATGTTCGTCGCCGAAGGGCTGCCCGCGATCGTCTGGGCGGTGTGCTGGTGGTTCCT
CGTGCAGGACAAGCCCGCGCAGGCGAAGTGGCTCACCGAATCGGACAAGCGCGATCTCGACGCCGCGCTCGCGGCCGAGC
AGGCGGCGCTCAAGCCGGTGCGCAACTATCGCGACGCGTTTCGCTCGCCCGCCGTCGTCAAGCTCTGCGCGCAGTACTTC
TGCTGGAGCATCGGCGTGTACGGCTTCGTGCTGTGGCTGCCGTCGATCGTGAAGAACGGCTCGGCGCTCGGCATGGTCGA
AACGGGGTGGCTGTCCGCGCTGCCGTATCTCGCCGCGACGATCGCGATGCTCGCCGCGTCGTGGGCGTCCGACAGGCTCG
GCTCGCGCAAGGGTTTCGTGTGGCCGTTCCTGCTGATCGGCGCCGCCGCGTTCGCCGCGTCGTATGCGCTCGGCTCGACG
CATTTCTGGCTGTCGTACGCGCTGCTCGTCGTCGCGGGCGCGGCGATGTACGCGCCGTACGGGCCGTTCTTCGCGATCGT
GCCGGAGCTCCTGCCGAAGAACGTCTCGGGCGGCGCGATGGCGCTCATCAACAGCATGGGCGCGCTCGGCTCGTTCGTCG
GCTCGTACGTCGTCGGCTATCTGAACGGCGCGACGGGCTCGCCCGCCGCGTCCTACGCGTTCATGAGCGCCGCGCTCGTC
GCGGCCGTCGTGCTCACGCTGTCGGTGAAGCAGGCGGGCGCGACGCCGACGCTCGCCCATCCGTTGCAAGGAAAGTGA

Upstream 100 bases:

>100_bases
GCCGCTCGCGCGATAAACCGCCTGTCCCGACGCAGGACGGGCACAATCGCGGCGAATCCCGCGTTTCATACGGCGCCGCT
CGACACAGGAGACACACATC

Downstream 100 bases:

>100_bases
ATACATGAAGCATCGCATCGTCGTCTACAAGCCGCTTCCCGGCGACGTGCTCGCGACCCTGCGCGAGCGCGCCGACGTCG
TGCTCGTCGAGGGCGCCGAC

Product: major facilitator family transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MSATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKTL
VFWSLVLWGACASLTGIVSNIPSLMAIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYL
VHEFGWRHMFVAEGLPAIVWAVCWWFLVQDKPAQAKWLTESDKRDLDAALAAEQAALKPVRNYRDAFRSPAVVKLCAQYF
CWSIGVYGFVLWLPSIVKNGSALGMVETGWLSALPYLAATIAMLAASWASDRLGSRKGFVWPFLLIGAAAFAASYALGST
HFWLSYALLVVAGAAMYAPYGPFFAIVPELLPKNVSGGAMALINSMGALGSFVGSYVVGYLNGATGSPAASYAFMSAALV
AAVVLTLSVKQAGATPTLAHPLQGK

Sequences:

>Translated_425_residues
MSATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKTL
VFWSLVLWGACASLTGIVSNIPSLMAIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYL
VHEFGWRHMFVAEGLPAIVWAVCWWFLVQDKPAQAKWLTESDKRDLDAALAAEQAALKPVRNYRDAFRSPAVVKLCAQYF
CWSIGVYGFVLWLPSIVKNGSALGMVETGWLSALPYLAATIAMLAASWASDRLGSRKGFVWPFLLIGAAAFAASYALGST
HFWLSYALLVVAGAAMYAPYGPFFAIVPELLPKNVSGGAMALINSMGALGSFVGSYVVGYLNGATGSPAASYAFMSAALV
AAVVLTLSVKQAGATPTLAHPLQGK
>Mature_424_residues
SATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKTLV
FWSLVLWGACASLTGIVSNIPSLMAIRFLLGVVEAAVMPAMLIFISNWFTKRERSRANTFLILGNPVTVLWMSVVSGYLV
HEFGWRHMFVAEGLPAIVWAVCWWFLVQDKPAQAKWLTESDKRDLDAALAAEQAALKPVRNYRDAFRSPAVVKLCAQYFC
WSIGVYGFVLWLPSIVKNGSALGMVETGWLSALPYLAATIAMLAASWASDRLGSRKGFVWPFLLIGAAAFAASYALGSTH
FWLSYALLVVAGAAMYAPYGPFFAIVPELLPKNVSGGAMALINSMGALGSFVGSYVVGYLNGATGSPAASYAFMSAALVA
AVVLTLSVKQAGATPTLAHPLQGK

Specific function: Component of the tartrate utilization system and may allow entry of tartrate and tartrate dehydrogenase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI6912666, Length=245, Percent_Identity=25.7142857142857, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI9966811, Length=370, Percent_Identity=25.9459459459459, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI9945322, Length=367, Percent_Identity=24.7956403269755, Blast_Score=76, Evalue=5e-14,
Organism=Homo sapiens, GI21322234, Length=259, Percent_Identity=26.2548262548263, Blast_Score=70, Evalue=3e-12,
Organism=Homo sapiens, GI154350196, Length=363, Percent_Identity=23.4159779614325, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI87082071, Length=418, Percent_Identity=27.511961722488, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI87082320, Length=432, Percent_Identity=25, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789152, Length=442, Percent_Identity=23.0769230769231, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1789515, Length=428, Percent_Identity=24.7663551401869, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI2367379, Length=287, Percent_Identity=24.0418118466899, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17552542, Length=318, Percent_Identity=26.4150943396226, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560030, Length=278, Percent_Identity=23.3812949640288, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17535049, Length=438, Percent_Identity=25.7990867579909, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI86561091, Length=334, Percent_Identity=25.748502994012, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533556, Length=362, Percent_Identity=23.7569060773481, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI115533554, Length=362, Percent_Identity=23.7569060773481, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=334, Percent_Identity=25.748502994012, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI25141316, Length=334, Percent_Identity=25.748502994012, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI193205400, Length=273, Percent_Identity=24.9084249084249, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565916, Length=193, Percent_Identity=24.3523316062176, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=276, Percent_Identity=26.0869565217391, Blast_Score=72, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI32565914, Length=193, Percent_Identity=24.3523316062176, Blast_Score=72, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17566884, Length=181, Percent_Identity=25.9668508287293, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71991453, Length=251, Percent_Identity=24.3027888446215, Blast_Score=65, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI71991448, Length=251, Percent_Identity=24.3027888446215, Blast_Score=65, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322612, Length=207, Percent_Identity=24.6376811594203, Blast_Score=74, Evalue=4e-14,
Organism=Drosophila melanogaster, GI45550460, Length=409, Percent_Identity=24.2053789731051, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24580790, Length=349, Percent_Identity=24.3553008595989, Blast_Score=91, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24655255, Length=371, Percent_Identity=24.5283018867925, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24583789, Length=356, Percent_Identity=23.0337078651685, Blast_Score=83, Evalue=4e-16,
Organism=Drosophila melanogaster, GI24655271, Length=411, Percent_Identity=23.6009732360097, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI20130135, Length=404, Percent_Identity=23.7623762376238, Blast_Score=82, Evalue=9e-16,
Organism=Drosophila melanogaster, GI28573299, Length=300, Percent_Identity=23, Blast_Score=78, Evalue=9e-15,
Organism=Drosophila melanogaster, GI24584153, Length=392, Percent_Identity=22.1938775510204, Blast_Score=76, Evalue=4e-14,
Organism=Drosophila melanogaster, GI28573708, Length=264, Percent_Identity=23.4848484848485, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI28573707, Length=264, Percent_Identity=23.4848484848485, Blast_Score=75, Evalue=9e-14,
Organism=Drosophila melanogaster, GI19922400, Length=260, Percent_Identity=23.0769230769231, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24648416, Length=273, Percent_Identity=23.4432234432234, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI21356189, Length=273, Percent_Identity=23.4432234432234, Blast_Score=72, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24653727, Length=377, Percent_Identity=24.4031830238727, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI24654215, Length=260, Percent_Identity=23.0769230769231, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI19920686, Length=362, Percent_Identity=23.4806629834254, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639764, Length=297, Percent_Identity=22.8956228956229, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI62484226, Length=295, Percent_Identity=24.406779661017, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24641682, Length=174, Percent_Identity=25.2873563218391, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24658674, Length=282, Percent_Identity=22.3404255319149, Blast_Score=69, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 45920; Mature: 45789

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCC
>Mature Secondary Structure 
SATLAIRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLG
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHH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CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7592429 [H]