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The map label for this gene is dppA [H]

Identifier: 83719763

GI number: 83719763

Start: 388228

End: 389814

Strand: Reverse

Name: dppA [H]

Synonym: BTH_I0349

Alternate gene names: 83719763

Gene position: 389814-388228 (Counterclockwise)

Preceding gene: 83720267

Following gene: 83718821

Centisome position: 10.23

GC content: 65.66

Gene sequence:

>1587_bases
ATGCGCTTCACGCACATCGCCGCCGCCGCGCTCGCCGCCGCTTCCGCCGTCGCCGTCGCCAAACCGCTGACGGTCTGCAC
CGAGTCGAGCCCGGACGGCTTCGACGTCGTCCAATACAACTCGCTCGTCACGACGAACGCATCCGCCGACGTCATCTTCA
ACACGCTCGTGTCGTACGACGAAGCAGCGAAGAAGGTGGTGCCCGCGCTCGCGGACAAATGGGACGTCAGCGCCGATGGC
CTCACGTACACGTTCCATCTGCGCCCGAACGTCGCGTTCCAGACGACCGACTACTTCAAGCCGACGCGCGCGCTCGACGC
GGACGACGTCGTCTTCACGTTCAGCCGGATGCTTGACGACGCGAATCCGTGGCACAAGGTCGCGGGCGCGAGCGGCTTTC
CGCACGCGCAATCGATGGGCCTCACGAAGCTCGTGAAGGCCGTCACGAAGCTCGACGATTCGACCGTGAAGTTCGAGCTG
AACGAGCCGAACGCGACGTTCGTGCCGATCCTGACGATGGGCTTCGCATCGATCTATTCGGCCGAATACGCGGGCCAGCT
GCTGAAGGCGGGCAAGCAGGCGGACCTGAACGCGAAGCCGGTCGGCACCGGGCCGTTCGCGCTGAAGAGCTACACGAAGG
ACGCGGTGATCCGCTACGAGGCGAACCCCACGTACTGGGGGCCGAAGCCGAAGGTCGAGCGCCTCATCTACGCGATCACG
CCCGATCCGTCGGTGCGCGCGCAGAAGGTGAAGGCGGGCGAATGCCAGATCGCGCTGTCGCCGAAGCCGCAGGACGTCGC
GGCCGCGAAGGCCGACCGCACGCTGAAGGTCGTCGAGACGCCCGCGTTCATGACCGCGTTCGTCGCGCTCAACACGCAGA
AGAAGCCGCTCGACAACGACAAGGTTCGCGAGGCGCTCAATCTCGCGTTCGATCGCGCGACGTACCTGAAGGTCGTGTTC
GACAACACCGCGACGCCCGCGACGAACCCGTATCCGCCGAACACGTGGAGCTACGCGAAATCGATCGCGCCGTATCCGTA
CGATCCGGCGAAGGCGAAGCAGTTGCTCGCCGCGGCGGGCTTCCCGAACGGCTTCTCGACGACGATCTGGGTGCGCCCGA
CGGGCAGCGTGCTGAATCCGAACCCCAAGGCGGGCGCGGAGCTGCTGCAGGCGGACCTCGCGAAGATCGGCGTGAAGGCG
GACGTGAAGGTGATCGAATGGGGCGAGCTGATCAAGCAGGCGAAGCTCGGCCAGCATGATCTGCTGTTCATGGGCTTCGC
GGGCGACAACGGCGATCCGGACAACATCCTCACGCCGCAATTCAGCTGCAACTCGGTGAAGTCGGGGCTGAACTTCGCGC
GCTATTGCGATCCGAAACTCGACAAGCTGATCGCCGACGCGAAGGAAACCGCCGACCAGGCGAAGCGCGCGAAGCTGTAC
GAGGCCGCGCAGAAGATCATCCACGACGAGGCGCTGTGGATTCCGCTCGGCTATCCGACCGCCGCGGCGATCACGCGGCC
GAACGTCGCCGGCTATCGCGTGAGCCCGTTCGGGCGGCAGCACTTCGACGCGGTGTCGGTGCAGTAG

Upstream 100 bases:

>100_bases
TAACGTCGAGCGCCCATTGACGGTATGCTATCCCGCTGGCGTGCGGCCGCTACGGCGTTGCCGCCCGCCGCCGTCAGAAT
TACGCCACGTGGGAGATCTC

Downstream 100 bases:

>100_bases
CGCGGCGACATCGCCGCCGCGGCCCGCGCGCAGCGCCGCGCGCCGGGCCGCGCTTGTCCGCATCGCGCGGCGCTTGCTAT
ACTCCCCGCACCTTTCCTCC

Product: peptide ABC transporter periplasmic peptide-binding protein

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 528; Mature: 528

Protein sequence:

>528_residues
MRFTHIAAAALAAASAVAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWDVSADG
LTYTFHLRPNVAFQTTDYFKPTRALDADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLTKLVKAVTKLDDSTVKFEL
NEPNATFVPILTMGFASIYSAEYAGQLLKAGKQADLNAKPVGTGPFALKSYTKDAVIRYEANPTYWGPKPKVERLIYAIT
PDPSVRAQKVKAGECQIALSPKPQDVAAAKADRTLKVVETPAFMTAFVALNTQKKPLDNDKVREALNLAFDRATYLKVVF
DNTATPATNPYPPNTWSYAKSIAPYPYDPAKAKQLLAAAGFPNGFSTTIWVRPTGSVLNPNPKAGAELLQADLAKIGVKA
DVKVIEWGELIKQAKLGQHDLLFMGFAGDNGDPDNILTPQFSCNSVKSGLNFARYCDPKLDKLIADAKETADQAKRAKLY
EAAQKIIHDEALWIPLGYPTAAAITRPNVAGYRVSPFGRQHFDAVSVQ

Sequences:

>Translated_528_residues
MRFTHIAAAALAAASAVAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWDVSADG
LTYTFHLRPNVAFQTTDYFKPTRALDADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLTKLVKAVTKLDDSTVKFEL
NEPNATFVPILTMGFASIYSAEYAGQLLKAGKQADLNAKPVGTGPFALKSYTKDAVIRYEANPTYWGPKPKVERLIYAIT
PDPSVRAQKVKAGECQIALSPKPQDVAAAKADRTLKVVETPAFMTAFVALNTQKKPLDNDKVREALNLAFDRATYLKVVF
DNTATPATNPYPPNTWSYAKSIAPYPYDPAKAKQLLAAAGFPNGFSTTIWVRPTGSVLNPNPKAGAELLQADLAKIGVKA
DVKVIEWGELIKQAKLGQHDLLFMGFAGDNGDPDNILTPQFSCNSVKSGLNFARYCDPKLDKLIADAKETADQAKRAKLY
EAAQKIIHDEALWIPLGYPTAAAITRPNVAGYRVSPFGRQHFDAVSVQ
>Mature_528_residues
MRFTHIAAAALAAASAVAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYDEAAKKVVPALADKWDVSADG
LTYTFHLRPNVAFQTTDYFKPTRALDADDVVFTFSRMLDDANPWHKVAGASGFPHAQSMGLTKLVKAVTKLDDSTVKFEL
NEPNATFVPILTMGFASIYSAEYAGQLLKAGKQADLNAKPVGTGPFALKSYTKDAVIRYEANPTYWGPKPKVERLIYAIT
PDPSVRAQKVKAGECQIALSPKPQDVAAAKADRTLKVVETPAFMTAFVALNTQKKPLDNDKVREALNLAFDRATYLKVVF
DNTATPATNPYPPNTWSYAKSIAPYPYDPAKAKQLLAAAGFPNGFSTTIWVRPTGSVLNPNPKAGAELLQADLAKIGVKA
DVKVIEWGELIKQAKLGQHDLLFMGFAGDNGDPDNILTPQFSCNSVKSGLNFARYCDPKLDKLIADAKETADQAKRAKLY
EAAQKIIHDEALWIPLGYPTAAAITRPNVAGYRVSPFGRQHFDAVSVQ

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=523, Percent_Identity=43.4034416826004, Blast_Score=471, Evalue=1e-134,
Organism=Escherichia coli, GI1787551, Length=502, Percent_Identity=35.4581673306773, Blast_Score=317, Evalue=1e-87,
Organism=Escherichia coli, GI1787052, Length=517, Percent_Identity=31.9148936170213, Blast_Score=229, Evalue=3e-61,
Organism=Escherichia coli, GI1789887, Length=496, Percent_Identity=26.008064516129, Blast_Score=138, Evalue=7e-34,
Organism=Escherichia coli, GI1787762, Length=477, Percent_Identity=25.7861635220126, Blast_Score=129, Evalue=5e-31,
Organism=Escherichia coli, GI1787495, Length=529, Percent_Identity=24.3856332703214, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI87081878, Length=525, Percent_Identity=25.1428571428571, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1789397, Length=494, Percent_Identity=25.5060728744939, Blast_Score=97, Evalue=3e-21,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 57185; Mature: 57185

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFTHIAAAALAAASAVAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYD
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHHHHH
EAAKKVVPALADKWDVSADGLTYTFHLRPNVAFQTTDYFKPTRALDADDVVFTFSRMLDD
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
ANPWHKVAGASGFPHAQSMGLTKLVKAVTKLDDSTVKFELNEPNATFVPILTMGFASIYS
CCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHH
AEYAGQLLKAGKQADLNAKPVGTGPFALKSYTKDAVIRYEANPTYWGPKPKVERLIYAIT
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEC
PDPSVRAQKVKAGECQIALSPKPQDVAAAKADRTLKVVETPAFMTAFVALNTQKKPLDND
CCCCCCHHEECCCCEEEEECCCCCHHHHHHCCCEEEEEECCHHHEEHEEECCCCCCCCHH
KVREALNLAFDRATYLKVVFDNTATPATNPYPPNTWSYAKSIAPYPYDPAKAKQLLAAAG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCC
FPNGFSTTIWVRPTGSVLNPNPKAGAELLQADLAKIGVKADVKVIEWGELIKQAKLGQHD
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCC
LLFMGFAGDNGDPDNILTPQFSCNSVKSGLNFARYCDPKLDKLIADAKETADQAKRAKLY
EEEEEECCCCCCCCCEECCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAAQKIIHDEALWIPLGYPTAAAITRPNVAGYRVSPFGRQHFDAVSVQ
HHHHHHHCCCEEEEECCCCCHHHEECCCCCCEEECCCCCCCCCEECCC
>Mature Secondary Structure
MRFTHIAAAALAAASAVAVAKPLTVCTESSPDGFDVVQYNSLVTTNASADVIFNTLVSYD
CCCHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCEEEEECCEEECCCCHHHHHHHHHHHH
EAAKKVVPALADKWDVSADGLTYTFHLRPNVAFQTTDYFKPTRALDADDVVFTFSRMLDD
HHHHHHHHHHHHCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHHCC
ANPWHKVAGASGFPHAQSMGLTKLVKAVTKLDDSTVKFELNEPNATFVPILTMGFASIYS
CCCHHHHCCCCCCCCHHHCCHHHHHHHHHHCCCCEEEEEECCCCCEEEHHHHHHHHHHHH
AEYAGQLLKAGKQADLNAKPVGTGPFALKSYTKDAVIRYEANPTYWGPKPKVERLIYAIT
HHHHHHHHHCCCCCCCCCCCCCCCCHHHHHCCCCEEEEEECCCCCCCCCCCCCEEEEEEC
PDPSVRAQKVKAGECQIALSPKPQDVAAAKADRTLKVVETPAFMTAFVALNTQKKPLDND
CCCCCCHHEECCCCEEEEECCCCCHHHHHHCCCEEEEEECCHHHEEHEEECCCCCCCCHH
KVREALNLAFDRATYLKVVFDNTATPATNPYPPNTWSYAKSIAPYPYDPAKAKQLLAAAG
HHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHCC
FPNGFSTTIWVRPTGSVLNPNPKAGAELLQADLAKIGVKADVKVIEWGELIKQAKLGQHD
CCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHHCCCCC
LLFMGFAGDNGDPDNILTPQFSCNSVKSGLNFARYCDPKLDKLIADAKETADQAKRAKLY
EEEEEECCCCCCCCCEECCCCCHHHHHHCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
EAAQKIIHDEALWIPLGYPTAAAITRPNVAGYRVSPFGRQHFDAVSVQ
HHHHHHHCCCEEEEECCCCCHHHEECCCCCCEEECCCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]